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Abstracts tagged "Ankylosing spondylitis (AS)"

  • Abstract Number: 1030 • ACR Convergence 2022

    Diagnostic Usefulness of Anti-PPM1A-IgM in Patients with Ankylosing Spondylitis

    Yeo jin lee1, Eun-Ju Lee2, Soo Min Ahn2, Seokchan Hong2, Ji Seon Oh3, Chang Keun Lee2, Bin Yoo2 and Yong Gil Kim2, 1Asan medical center, Seoul, Republic of Korea, 2Department of Rheumatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea, Seoul, Republic of Korea, 3Department of Information Medicine, Big Data Research Center, Asan Medical Center, Seoul, Republic of Korea

    Background/Purpose: Ankylosing spondylitis (AS) has been known to have auto-inflammatory nature, hence, the efficacy of autoantibodies is low. However, studies on autoantibodies are ongoing, with…
  • Abstract Number: 1425 • ACR Convergence 2022

    Treatment Persistence and Switching Patterns of ABP 501 (AMGEVITA®) in German Patients with Rheumatic Diseases

    Ran Jin1, Silvia Kruppert2, Florian Scholz2, Marc Hammer2, Greg Kricorian1, David Collier3 and Jonathan Kay4, 1Amgen, Inc., Thousand Oaks, CA, 2IQVIA, Frankfurt, Germany, 3Amgen Inc., Simi Valley, CA, 4Division of Rheumatology, Department of Medicine, UMass Chan Medical School and UMass Memorial Medical Center, Worcester, MA

    Background/Purpose: ABP 501 is the first adalimumab (ADA) biosimilar approved by the European Medical Association and the Food and Drug Administration for the treatment of…
  • Abstract Number: PP07 • ACR Convergence 2022

    Remissions and Vigilance

    Michael Scepaniak, Cockeysville, MD

    Background/Purpose: I've been diagnosed with spondyloarthritis (SpA) for a little more than 7 1/2 years. That diagnosis was preceded by roughly 9 months of significant…
  • Abstract Number: 0399 • ACR Convergence 2022

    ASAS Recommendations for Requesting and Reporting Imaging in Patients with Suspected Axial Spondyloarthritis

    Torsten Diekhoff1, Iris Eshed2, Chiara Giraudo3, Hildrun Haibel4, Kay-Geert Hermann5, Manouk de Hooge6, Lennart Jans7, Anne Jurik8, Robert G Lambert9, Pedro Machado10, Walter P Maksymowych11, Michael Mallinson12, Helena Marzo-Ortega13, Victoria Navarro-Compán14, Susanne Pedersen15, Mikkel Østergaard16, Monique Reijnierse17, Martin Rudwaleit18, Fernando Andres Sommerfleck19, Ulrich Weber20, Xenofon Baraliakos21 and Denis Poddubnyy22, 1Charité – Universitätsmedizin Berlin, Berlin, Germany, 2Sheba Medical Center, Tel Aviv, Israel, 3University of Padova, Padova, Italy, 4Charité - Universitätsmedizin, Berlin, Berlin, Germany, 5Charité - Universitätsmedizin Berlin, Berlin, Germany, 6Ghent University Hospital, Luxembourg, Luxembourg, 7Ghent University Hospital, Ghent, Belgium, 8Aarhus University Hospital, Aarhus, Denmark, 9University of Alberta, Edmonton, AB, Canada, 10University College London, London, United Kingdom, 11Department of Medicine, University of Alberta, Edmonton, AB, Canada, 12ASIF Axial Spondyloarthritis International Federation, London, United Kingdom, 13Leeds Teaching Hospitals Trust and University of Leeds, Leeds, United Kingdom, 14Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain, 15Rigshospitalet, København, Denmark, 16Rigshospitalet, University of Copenhagen, Glostrup, Denmark, 17Leiden University Medical Center, Leiden, Netherlands, 18University of Bielefeld, Klinikum Bielefeld, Bielefeld; Germany Klinikum Bielefeld and Charité Berlin, Germany, and Gent University, Gent, Belgium, 19Sanatorio Julio Mendez, Buenos Aires, Argentina, 20Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, 21Rheumazentrum Ruhrgebiet Herne, Herne, Germany, 22Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité – Universitätsmedizin Berlin, Berlin, Germany

    Background/Purpose: Clinicians face uncertainties in their daily practice when requesting imaging for patients with suspicion of axial spondyloarthritis (axSpA) or producing a report because requirements…
  • Abstract Number: 0424 • ACR Convergence 2022

    The Efficacy and Safety of CT-P13 as First-line and Subsequent-line Therapy in Patients with Ankylosing Spondylitis: Real-life Data from TURKBIO Cohort

    Sadettin Uslu1, Semih Gulle1, Gercek Can2, Soner Senel3, Sedat Capar4, Huseyin ediz dalkilic5, Servet Akar6, Suleyman Serdar Koca7, Abdurrahman Tufan8, Ayten Yazici9, Sema Yilmaz10, Nevsun Inanc11, Merih Birlik1, Dilek Solmaz12, Ayse Cefle9, Berna Goker13, Servet Yolbas14, Niels Steen Krough15, Neslihan Yilmaz16, Sukran Erten17, Cemal Bes18, Ozgul Soysal19, Mehmet Akif Ozturk13, Seminur Haznedaroglu13, Sule Yavuz16, Haner Direskeneli20, Fatoş Onen21 and Ismail Sari22, 1Dokuz Eylul University School of Medicine Division of Rheumatology, Izmir, Turkey, 2Dokuz Eylul University School of Medicine Division of Rheumatology, Istanbul, Turkey, 3Erciyes University School of Medicine Division of Rheumatology, Kayseri, Turkey, 4Dokuz Eylul University Faculty of Science Department of Statistics, Izmir, Turkey, 5Uludag University School of Medicine Division of Rheumatology, Bursa, Turkey, 6Izmir Katip Celebi University School of Medicine, Izmir, Turkey, 7Firat University School of Medicine Division of Rheumatology, Elazıg, Turkey, 8Gazi University Medical Faculty Hospital, Istanbul, Turkey, 9Kocaeli University School of Medicine Division of Rheumatology, Kocaeli, Turkey, 10Selcuk University School of Medicine Division of Rheumatology, Konya, Turkey, 11Marmara University School of Medicine, Division of Rheumatology, Istanbul, Turkey, 12Kâtip Celebi University School of Medicine Division of Rheumatology, Izmir, Turkey, 13Gazi University School of Medicine Division of Rheumatology, Ankara, Turkey, 14Inonu University School of Medicine Division of Rheumatology, Malatya, Turkey, 15Zitelab Aps, Kopenhag, Denmark, 16Demiroglu Bilim University School of Medicine Division of Rheumatology, Istanbul, Turkey, 17Yildirim Beyazit University School of Medicine Division of Rheumatology, Ankara, Turkey, 18Basaksehir Cam and Sakura ospital, Division of Rheumatology, Istanbul, Turkey, 19Celal Bayar University, School of Medicine Division of Rheumatology, Manisa, Turkey, 20Marmara University School of Medicine Division of Rheumatology, Istanbul, Turkey, 21Dokuz Eylul University, Faculty of Medicine, Rheumatology, İzmir, Turkey, 22Dokuz Eylul University School of Medicine Division of Rheumatology, İzmir, Turkey

    Background/Purpose: In this study, it was aimed to evaluate the long-term drug survival, efficacy and safety of infliximab biosimilar CT-P13 in Turkish patients diagnosed with…
  • Abstract Number: 1034 • ACR Convergence 2022

    Characterization of Non-radiographic Axial Spondyloarthritis Patients and the Burden of Disease in Routine Clinical Practice

    Kathryn Starzyk, Pam Kumparatana and roger Meng, OM1, Inc., Boston, MA

    Background/Purpose: Axial spondyloarthritis [AxSpA and particularly non-radiographic (nr)AxSpA] has one of the longest diagnostic delays in rheumatology. Although improving, lack of radiographic evidence of disease…
  • Abstract Number: 1426 • ACR Convergence 2022

    Year-two Follow-up Results of an Observational Study Conducted in Rheumatoid Arthritis, Ankylosing Spondylitis and Psoriatic Arthritis Patients Treated with Infliximab Biosimilar CT-P13 in a Real-life Setting

    Bruno Fautrel1, Maryse Assing2, Nadir Mammar2, Yves Brault2 and Hubert Marotte3, 1Sorbonne University Paris, France and Pierre Louis Institute of Epidemiology and Public Health, Paris, France, Paris, France, 2Pfizer, Paris, France, 3INSERM 1059, Saint-Etienne, France

    Background/Purpose: ReFLECT study has been carried out to investigate real life use of CT-P13, the first monoclonal antibody biosimilar to infliximab (IFX) originator.Methods: ReFLECT is…
  • Abstract Number: PP11 • ACR Convergence 2022

    Exercise as a Supportive Treatment for My Ankylosing Spondylitis

    Sara King-Dowling, Children's Hospital of Philadelphia, Philadelphia, PA

    Background/Purpose: Patients with autoimmune rheumatic diseases (ARDs) are often caught in a paradox as they experience mobility challenges, but long periods of immobility cause increased…
  • Abstract Number: 0402 • ACR Convergence 2022

    Opioid Use and Healthcare Utilization in Adults with PsA and AS

    Alexis Ogdie1, Sofia Pedro2, Jean Liew3 and Kaleb Michaud4, 1Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2Forward, The National Databank for Rheumatic Diseases, Wichita, KS, 3Boston University, Boston, MA, 4University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Opioid use among individuals with spondyloarthritis is common, reported to be ~20-30% in some cohorts. Data on whether this subset of patients have higher…
  • Abstract Number: 0425 • ACR Convergence 2022

    Upadacitinib Pharmacokinetics and Exposure-Response Relationships for Efficacy and Safety in Axial Spondyloarthritis – Analyses of the Phase 3 Studies (SELECT-AXIS 1 and 2)

    Sumit Bhatnagar1, Doerthe Eckert2, Sven Stodtmann2, In-Ho Song3, Peter Wung3, Wei Liu3 and Mohamed-Eslam Mohamed3, 1AbbVie, Highland Park, IL, 2AbbVie, Ludwigshafen, Germany, 3AbbVie, Inc., North Chicago, IL

    Background/Purpose: The efficacy and safety profile of 15 mg once-daily (QD) upadacitinib (UPA), an oral, reversible, JAK inhibitor has been established in axial spondyloarthritis (axSpA),…
  • Abstract Number: 1036 • ACR Convergence 2022

    Efficacy and Safety of Tofacitinib in Patients with Psoriatic Arthritis or Ankylosing Spondylitis by History of Cigarette Smoking

    Alexis Ogdie1, Lars Erik Kristensen2, Enrique R Soriano3, Servet Akar4, Yanhui Sun5, David Gruben6, Lara Fallon7, Cassandra D Kinch8 and Dafna Gladman9, 1Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2The Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark, 3Rheumatology Unit and University Institute, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 4Izmir Katip Celebi University School of Medicine, Izmir, Turkey, 5Pfizer CRDC, Shanghai, China, 6Pfizer Inc, Groton, CT, 7Pfizer Inc, Montréal, QC, Canada, 8Pfizer Canada ULC, Kirkland, Canada, 9Toronto Western Hospital, Schroeder Arthritis Institute, Toronto, ON, Canada

    Background/Purpose: In patients (pts) with PsA and AS, smoking may be associated with an increased comorbidity burden, and greater responses to TNF inhibitors (TNFi) are…
  • Abstract Number: 1489 • ACR Convergence 2022

    Incidence of Herpes Zoster Events After the Three Doses of the BNT162b2 mRNA Vaccine in Patients with Spondyloarthritis

    Devy Zisman1, Noa Hayat1, Amir Haddad2, Joy Feld3, Tal Gazitt1, Idit Lavi1, Ilan feldhamer4, ARNON DOV COHEN4 and Walid Saliba1, 1Carmel Medical Center, Haifa, Israel, 2Carmel Medical Centre, Haifa, Israel, 3Carmel and Zvulun Medical Centre, Haifa, Israel, 4Clalit Health Services, Tel Aviv, Israel

    Background/Purpose: The importance and efficacy of anti COVID-19 vaccine in coping with the pandemic are well established, but inconsistencies remain in the data regarding side…
  • Abstract Number: PP25 • ACR Convergence 2022

    From Denial of Spondyloarthritis to Becoming a Support Group Leader and Medical Doctor of Rheumatology: A Patient’s Perspective

    Shung Chiu1 and Mei Nee Chiu2, 1Spondylitis Association of America, Ludhiana, Punjab, India, 2University Institute of Pharmaceutical Sciences, Panjab University, Ludhiana, Punjab, India

    Background/Purpose: From being a table tennis champion to getting into medical school, I thought my life was smooth sailing. But little did I know it…
  • Abstract Number: 0014 • ACR Convergence 2022

    The Expanded CD21 Low B Cell Subpopulation in Ankylosing Spondylitis Consists Mainly of Antigen-Inexperienced Cells

    Rick Wilbrink1, Linda van der Weele2, Anneke Spoorenberg1, Niek De Vries2, Frans Kroese1 and Gwenny Verstappen1, 1University Medical Center Groningen, Groningen, Netherlands, 2University Medical Center Amsterdam, Amsterdam, Netherlands

    Background/Purpose: The role of B cells in the pathogenesis of ankylosing spondylitis (AS) remains relatively understudied. Nevertheless, available evidence shows presence of B cells at…
  • Abstract Number: 0403 • ACR Convergence 2022

    Efficacy and Safety of Ixekizumab in Chinese Patients with Radiographic Axial Spondyloarthritis: 16-Week Results from a Phase 3 Study

    Yu Xue1, Jiankang Hu2, Dongzhou Liu3, Jingyang Li4, Huaxiang Wu5, Chunyu Tan6, Lie Dai7, Mengru Liu8, Hongying Li8 and Hejian Zou1, 1Huashan Hospital affiliated to Fudan University, Shanghai, China, 2Jiangxi Pingxiang People’s Hospital, Shanghai, China, 3Shenzhen People’s Hospital (The Second Clinical Medical College of Jinan University), Shanghai, China, 4Zhuzhou Central Hospital, Shanghai, China, 5The Second Affiliated Hospital Zhejiang University School of Medicine, Shanghai, China, 6West China Hospital of Sichuan University, Shanghai, China, 7Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Shanghai, China, 8Eli Lilly and Company, Shanghai, China

    Background/Purpose: Ixekizumab, a high-affinity monoclonal antibody that selectively targets interleukin-17A, has demonstrated efficacy in global clinical trials in patients with radiographic axial spondyloarthritis (r-axSpA)/ankylosing spondylitis…
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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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