Abstract Number: 1221 • ACR Convergence 2020
Evaluation of Methotrexate Efficacy and Exploration of Metabolites Associated with Disease Activity in Collagen-induced Arthritis Mouse Model
Background/Purpose: Methotrexate (MTX) is cornerstone of therapy for rheumatoid arthritis. However, response to MTX is variable and unpredictable among patients. Therefore, there is a critical…Abstract Number: 1410 • ACR Convergence 2020
Resident Memory T Cells Persist in Joints of Anakinra-Treated Mice in Spontaneous Arthritis Model
Background/Purpose: Inflammatory arthritis is characterized by chronic inflammation of joints which can be suppressed with immunomodulatory therapy. However, two-thirds of patients will have an arthritis…Abstract Number: 1447 • ACR Convergence 2020
Vitamin D Deficiency Enhances Antiphospholipid Antibody-Mediated Thrombosis in a Passive Immunization Mouse Model
Background/Purpose: Abnormal vitamin D levels occur frequently in antiphospholipid (APS) patients and are correlated with thrombosis. It remains unclear however if vitamin D deficiency observed…
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