Abstract Number: 1066 • 2018 ACR/ARHP Annual Meeting
Tocilizumab Effect on Serum Angiogenic Factors in Rheumatoid Arthritis Patients
Background/Purpose: Several inducers of angiogenesis have been shown to play a central role in rheumatoid arthritis (RA) pathogenesis: VEGF (Vascular Endothelial Growth Factor), EMMPRIN (Extracellular…Abstract Number: 1062 • 2018 ACR/ARHP Annual Meeting
Linking Systemic Angiogenic Markers to Synovial Vascularization in Rheumatoid Arthritis
Background/Purpose: Neoangiogenesis is a crucial event to promote the development of the hyperplasic proliferative pathologic synovium in Rheumatoid arthritis (RA). Ultrasound (US) is sensitive for…Abstract Number: 2576 • 2016 ACR/ARHP Annual Meeting
uPAR Promotes Tumor-like Biologic Role of Fibroblast-like Synoviocytes through PI3K/Akt Signaling Pathway in Patients with Rheumatoid Arthritis
Background/Purpose: Urokinase-type plasminogen activator receptor (uPAR), is a multi-functional receptor on cell surface, widely present in endothelial cells, fibroblasts, and a variety of malignant cells.…Abstract Number: 10 • 2015 ACR/ARHP Annual Meeting
CD13/Aminopeptidase N Contributes to Angiogenesis and Monocyte Chemotaxis in Rheumatoid Arthritis
Background/Purpose: Aminopeptidase N (CD13, EC 3.4.11.2) is a metalloproteinase expressed on the surface of fibroblast like synoviocytes (FLS), and as a soluble protein in serum…Abstract Number: 17 • 2015 ACR/ARHP Annual Meeting
Disentangling the Role of Hypoxia-Inducible Factor 1 and 2 in the Adaption Process of Human Microvascular Endothelial Cells to Pathophysiological Hypoxia
Background/Purpose: Angiogenesis is a prominent feature of the pathogenesis of RA. Although new blood vessels deliver oxygen to the augmented inflammatory cell mass, the neovascular…