ACR Meeting Abstracts

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Abstracts tagged "Angiogenesis and rheumatoid arthritis (RA)"

  • Abstract Number: 1066 • 2018 ACR/ARHP Annual Meeting

    Tocilizumab Effect on Serum Angiogenic Factors in Rheumatoid Arthritis Patients

    Muna Elias1, Michal Amit Rahat2, Joy Feld1, Itzhak Rosner3, Lisa Kaly4, Idit Lavi5, Tal Gazitt6 and Devy Zisman7, 1Rheumatology Unit Carmel Medical Center, Haifa, Israel, 2Immunotherapy laboratory, Carmel medical center, Haifa, Israel, 3Rheumaoloy Unit, Bnai Zion Medical Center, Haifa, Israel, 4Rheumatology unit, Bnai-Zion Medical Center, Haifa, Israel, 5Epidemiology Unit Carmel Medical Center, Haifa, Israel, 6Rheumatology unit, Carmel medical center, Haifa, Israel, 7Rheumatology Unit, Carmel Medical Center, Haifa, Israel

    Background/Purpose: Several inducers of angiogenesis have been shown to play a central role in rheumatoid arthritis (RA) pathogenesis: VEGF (Vascular Endothelial Growth Factor), EMMPRIN (Extracellular…
  • Abstract Number: 1062 • 2018 ACR/ARHP Annual Meeting

    Linking Systemic Angiogenic Markers to Synovial Vascularization in Rheumatoid Arthritis

    Agathe Leblond1, Sonia Pezet1, Anne priscille Trouvin2, Muriel Elhai2, Virginie Gonzalez1, Yannick Allanore3 and Jérôme Avouac2, 1Université Paris Descartes, Sorbonne Paris Cité, INSERM U1016, Institut Cochin, CNRS UMR8104, Paris, France, Paris, France, 2Université Paris Descartes, Sorbonne Paris Cité, Service de Rhumatologie A, Hôpital Cochin, Paris, France, Paris, France, 3Service de Rhumatologie A, Hôpital Cochin, Paris, France

    Background/Purpose: Neoangiogenesis is a crucial event to promote the development of the hyperplasic proliferative pathologic synovium in Rheumatoid arthritis (RA). Ultrasound (US) is sensitive for…
  • Abstract Number: 2576 • 2016 ACR/ARHP Annual Meeting

    uPAR Promotes Tumor-like Biologic Role of Fibroblast-like Synoviocytes through PI3K/Akt Signaling Pathway in Patients with Rheumatoid Arthritis

    Yan Liu1, Yunfeng Pan2 and Song Guo Zheng3, 1Center for Clinic Immunology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Guangzhou, China, 2Rheumatology, third affiliated hospital of Sun Yat-sen Universtiy, Guangzhou, China, 3Medicine/Rheumatology, Penn State Hershey Medical Center, Hershey, PA

    Background/Purpose: Urokinase-type plasminogen activator receptor (uPAR), is a multi-functional receptor on cell surface, widely present in endothelial cells, fibroblasts, and a variety of malignant cells.…
  • Abstract Number: 10 • 2015 ACR/ARHP Annual Meeting

    CD13/Aminopeptidase N Contributes to Angiogenesis and Monocyte Chemotaxis in Rheumatoid Arthritis

    Rachel Morgan1, M. Asif Amin1, Jeffrey Ruth1, Gautam Edhayan2, Stephanie Rasmussen3 and David A. Fox1, 1Internal Medicine, Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, MI, 2Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, MI, 3Division of Rheumatology, University of Michigan, Ann Arbor, MI

    Background/Purpose: Aminopeptidase N (CD13, EC 3.4.11.2) is a metalloproteinase expressed on the surface of fibroblast like synoviocytes (FLS), and as a soluble protein in serum…
  • Abstract Number: 17 • 2015 ACR/ARHP Annual Meeting

    Disentangling the Role of Hypoxia-Inducible Factor 1 and 2 in the Adaption Process of Human Microvascular Endothelial Cells to Pathophysiological Hypoxia

    Martin Hahne1, Peggy Kunath2, Mathias Mursell3, Cindy Strehl2, Gerd Burmester4, Frank Buttgereit2 and Timo Gaber2, 1Miltenyi Biotec GmbH, Berlin, Germany, 2Department of Rheumatology and Clinical Immunology, Charité – Universitätsmedizin Berlin, Berlin, Germany, 3German Rheumatism Research Center (DRFZ), Berlin, Germany, 4Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany

    Background/Purpose: Angiogenesis is a prominent feature of the pathogenesis of RA. Although new blood vessels deliver oxygen to the augmented inflammatory cell mass, the neovascular…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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