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Abstracts tagged "ANCA"

  • Abstract Number: 2516 • ACR Convergence 2025

    Mortality Trends in Primary Systemic Vasculitis in the United States (1999–2023)

    Rameez Qasim1, Sabah Mohib2, Muhammad Ali3 and Khadija Mohib4, 1Allama Iqbal Medical College Lahore, Lahore, Pakistan, 2N/A, Reseda, CA, 3Dow International Medical College, Karachi, Sindh, Pakistan, 4Kirk Kerkorian School of Medicine at UNLV, Las Vegas, NV

    Background/Purpose: Primary systemic vasculitides comprise a group of immunological disorders that inflame blood vessel walls and are categorized by the size of the blood vessels…
  • Abstract Number: 2504 • ACR Convergence 2025

    Variables Associated with In-Hospital Mortality in Adult Eosinophilic Granulomatosis with Polyangiitis from the National Inpatient Sample Database 2017-2021

    Anuya Natu1, Isadora Small2, Shilpa Arora3 and Augustine Manadan4, 1John H Stroger, Jr. Hospital of Cook County, Chicago, IL, 2The Latin School of Chicago, Chicago, IL, 3Cook County Hospital, Chicago, IL, 4Rush University Medical Center, Chicago, IL

    Background/Purpose: Eosinophilic Granulomatosis with Polyangiitis (EGPA) is a rare systemic vasculitis that can lead to significant morbidity and mortality. This study aims to evaluate the…
  • Abstract Number: 1912 • ACR Convergence 2025

    Cutaneous manifestations of vasculitis: A cross-sectional analysis from an international cohort

    Robert Micheletti1, William Song1, Brian Chu2, Lynne Allen-Taylor3, Joel Gelfand3, Peter Grayson4, Cristina Ponte5, Joanna Robson6, Ravi Suppiah7, Raashid Luqmani8, Richard Watts9 and Peter Merkel10, 1Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 2Brown University Health, Providence, RI, 3University of Pennsylvania, Philadelphia, 4National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Chevy Chase, MD, 5Unidade Local de Saúde de Santa Maria, Lisbon, Portugal, 6University of the West of England Bristol, Bristol, United Kingdom, 7Health New Zealand - Te Toka Tumai, Auckland, New Zealand, 8University of Oxford, Oxford, United Kingdom, 9University of East Anglia, Norwich, United Kingdom, 10University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Vasculitis is a group of rare, multisystem diseases which may involve the skin. Characterization of the frequency, type, and significance of cutaneous manifestations in…
  • Abstract Number: 1693 • ACR Convergence 2025

    Characterizing ANCA-specific B Cells in ANCA-associated Vasculitis

    Laura van Dam1, Mengrui Zhang1, Shima Parsafar2, Audra Horomanski3, Sajede Rasouli2, Orr Sharpe2, Jolijn van Leeuwen4, Tobias Lanz2, Cees van Kooten4, Onno Teng5 and William H. Robinson3, 1Stanford University, Stanford, CA, 2Stanford University, Stanford, 3Stanford University, Palo Alto, CA, 4Leiden University Medical Center, Leiden, Netherlands, 5Leiden University Medical Center, Leiderdorp, Netherlands

    Background/Purpose: Anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) is a severe autoimmune disease, characterized by ANCAs targeting myeloperoxidase (MPO) or proteinase-3 (PR3). ANCA-specific B cells have…
  • Abstract Number: 1605 • ACR Convergence 2025

    Combined Anti-IL-5/IL-5R and Dupilumab Therapy in Eosinophilic Granulomatosis with Polyangiitis: A European Retrospective Study

    Miriam Guerini1, Pavel Novikov2, Roberto Padoan3, Georgina Espigol-Frigole4, Jan Willem Cohen Tervaert5, Vincent Grobost6, Laurent Guilleminault7, Jan Walter Schroeder8, Bernhard Hellmich9, Joana Martins-Martinho10, Camillo Ribi11, Mathieu Groh12 and Benjamin Terrier13, 1IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy, 2Sechenov University, Moscow, Russia, 3University of Padova, Padova, Italy, 4Hospital Clínic de Barcelona, Barcelona, Spain, 5University of Alberta, Edmonton, AB, Canada, 6Internal medicine, CHU Clermont Ferrand Estaing, Clermont Ferrand, France, 7CHU Toulouse, Toulouse University, Toulouse, France, 8ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy, 9Klinik für Innere Medizin, Rheumatologie und Immunologie, medius Klinik Kirchheim, Kirchheim unter Teck, Germany, 10ULS Santa Maria, Lisbon, Portugal, 11Lausanne University Hospital / University of Lausanne, Lausanne, Switzerland, 12Hôpital Foch, Suresnes, France, 13Cochin Hospital, Paris, France

    Background/Purpose: Eosinophilic granulomatosis with polyangiitis (EGPA) is a small-vessel vasculitis characterized by asthma, ear, nose, and throat (ENT) symptoms, eosinophilia, and systemic involvement. Despite the…
  • Abstract Number: 1597 • ACR Convergence 2025

    Effectiveness and Safety of Rituximab Biosimilars in Small Vessel Vasculitis: a Systematic Literature Review

    Caitlyn Kanters1, Joo Young Lee2, Christian Pagnoux3, Lillian Barra4, Jean-Paul Makhzoum5 and Arielle Mendel6, 1McGill University, Montreal, Canada, 2Research institute of the McGill University Health Center, Montreal, QC, Canada, 3Mount Sinai Hospital, University Health Network, Toronto, and Canadian Vasculitis Research Network (CanVasc), Toronto, ON, Canada, 4Western University, London, ON, Canada, 5University of Montreal, Montreal, 6McGill University Health Centre, Montreal, Canada

    Background/Purpose: To evaluate the safety and effectiveness of rituximab biosimilars in the treatment of small vessel vasculitis.Methods: The Medline, CINAHL, Cochrane, Embase and Web of…
  • Abstract Number: 1162 • ACR Convergence 2025

    Antineutrophil cytoplasmic antibody-associated isolated interstitial lung disease

    Javier Narváez1, Pol Maymó-Paituvi2, Vanesa Vicens Zygmunt3, Guadalupe Bermudo4, Martí Aguilar-Coll5, Montserrat Roig Kim2, Laia De Daniel Bisbe2, Joan Miquel Nolla2 and Maria Molina-Molina4, 1Hospital Universitario de Bellvitge, Barcelona, Spain, 2Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Spain, 3Interstitial Lung Disease Unit. Department of Pneumology. Hospital Universitario de Bellvitge, Barcelona, Spain, 4Interstitial Lung Disease Unit. Department of Pneumology. Hospital Universitario de Bellvitge., Barcelona, Spain, 5Department of Rheumatology. Hospital Universitario de Bellvitge, Barcelona, Spain

    Background/Purpose: There is increasing evidence of the association between interstitial lung disease (ILD) and ANCA positivity without other manifestations of systemic vasculitis. The prognosis of…
  • Abstract Number: 0715 • ACR Convergence 2025

    Supervised machine learning algorithm to identify patients with eosinophilic granulomatosis with polyangiitis in France

    Benjamin Terrier1, Solenne Tauty2, Anouar Salhi2, Francoise Bugnard2, Steve Benard2, Vincent Cottin3, Camille Taillé4 and Xavier Puéchal5, 1Cochin Hospital, Paris, France, 2Steve Consultants, Lyon, France, 3National Reference Center for Rare Pulmonary Diseases, Louis Pradel Hospital, Hospices Civils de Lyon, Claude Bernard University Lyon 1, UMR 754, ERN-LUNG, Lyon, France, Lyon, France, 4Bichat hospital, APHP, Paris, France, 5Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hospital Cochin, and Université Paris Cité, Paris ( 75014 ), Ile-de-France, France

    Background/Purpose: Identifying patients with eosinophilic granulomatosis with polyangiitis (EGPA) in claims databases such as the French National Health Data System (SNDS) is a major challenge…
  • Abstract Number: 0727 • ACR Convergence 2025

    Higher rates of severe sensorineural hearing loss in granulomatosis with polyangiitis (GPA) compared to other antineutrophil cytoplasmic antibody (ANCA) associated vasculitis

    Sehreen Mumtaz1, Kindalem Fentie2, Joseph Parker2, Emily Craver1, Vikas Majithia3 and Andy Abril4, 1Mayo Clinic Florida, Jacksonville, FL, 2Mayo Clinic, Florida, Jacksonville, FL, 3Mayo Clinic Hospital, Jacksonville, FL, 4Mayo Clinic Florida, Jacksonville

    Background/Purpose: Hearing loss in antineutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is one of the commonly reported manifestations of organ damage in AAV with predominantly…
  • Abstract Number: 0728 • ACR Convergence 2025

    Incidence and Clinical Characteristics of ANCA-Associated Vasculitis: A Nationwide Study in Spain

    Susana Romero-Yuste1, Marta Domínguez-Álvaro2, Antonio Fernández-Nebro3, Miquel Blasco4, Beatriz Ventosa5, Javier Narváez6, Gema Fernández7, Iñigo Rúa-Figueroa8, Desirée Luis-Rodríguez9 and Manuel Macía10, 1University Hospital Complex of Pontevedra, Pontevedra, Spain, 2Sociedad Española de Reumatología, Madrid, Spain, 3Hospital Regional Universitario de Malaga, Malaga, Spain, Malaga, Spain, 4Hospital clinic Barcelona, Barcelona Spain, Spain, 5Spanish Society of Rheumatology, Madrid, Spain, 6Hospital Universitario de Bellvitge, Barcelona, Spain, 7Hospital la Paz, Madrid, Madrid, Spain, 8Hospital de Gran Canaria Doctor Negrin, Las Palmas GC, Spain, 9Hospital Universitario Nuestra Señora de Candelaria, Tenerife, Spain, 10Hospital Universitario Nuestra Señora de Candelaria,, Tenerife, Spain

    Background/Purpose: ANCA-associated vasculitides (AAV)—granulomatosis with polyangiitis (GPA), eosinophilic granulomatosis with polyangiitis (EGPA), and microscopic polyangiitis (MPA)are rare but severe systemic vasculitides with significant morbidity and…
  • Abstract Number: 0724 • ACR Convergence 2025

    Risk of Drug Induced Liver Injury with Use of Avacopan in ANCA Vasculitis – Results from Real-World Data

    Milad Heydari-Kamjani1, Elleson Harper2 and Haseeb Chaudhary3, 1University Hospitals Cleveland Medical Center/ Case Western Reserve University, Cleveland, OH, 2University Hospitals Cleveland Medical Center/Case Western Reserve University, Cleveland, OH, 3Case Western Reserve University, Westlake, OH

    Background/Purpose: Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a systemic autoimmune vasculitis. Avacopan, a novel oral C5a receptor inhibitor, has emerged as an adjunct therapy…
  • Abstract Number: 0150 • ACR Convergence 2025

    Mortality in Anca-associated Vasculitis

    Fabricio Benavides Villanueva1, Vanesa Calvo-Río2, Diana Prieto-Peña3, Monica Renuncio-García4, Adrian Martin-Gutierrez5, Amparo Sanchez-Lopez6, Claudia Poo-fernandez7, Clara Escagedo-Cagigas8, maria Rodríguez-Vidriales8 and Ricardo Blanco2, 1Division of Rheumatology, Hospital Universitario Marques de Valdecilla, IDIVAL, Immunopathology Group,Santander, Spain, Santander, Spain, 2Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain, Santander, Cantabria, Spain, 3Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain., Santander, Spain, 4Division of Immunology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain., Santander, Cantabria, Spain, 5Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain., Renedo de Piélagos, Spain, 6Division of Dermatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain., Santander, Cantabria, Spain, 7Division of Pneumology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain., Santander, Cantabria, Spain, 8Division of Nephrology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain., Santander, Cantabria, Spain

    Background/Purpose: Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), include Granulomatosis with Polyangiitis (GPA), Microscopic Polyangiitis (MPA), and Eosinophilic Granulomatosis with Polyangiitis (EGPA). Mortality rates are scare,…
  • Abstract Number: 0729 • ACR Convergence 2024

    Factors Associated with Pauci-immune Glomerulonephritis in Patients Undergoing Renal Biopsy with Positive ANCA Results

    Jiyun Lee1, Yeo-Jin Lee2, Mi-Ra Cho3, Young-Eun Kim4, Soo Min Ahn4, Ji Seon Oh3, Yong-Gil Kim3, Chang-Keun Lee3, Bin Yoo3 and Seokchan Hong3, 1University of Ulsan College of Medicine, Seoul, Republic of Korea, 2Asan medical center, Seoul, South Korea, 3Asan Medical Center, Seoul, Republic of Korea, 4Asan medical center, University of Ulsan College of Medicine, Seoul, Republic of Korea

    Background/Purpose: Pauci-immune glomerulonephritis (GN) is a renal manifestation of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). When patients present with positive ANCA results and urinary abnormalities…
  • Abstract Number: 2512 • ACR Convergence 2024

    French Multicenter Retrospective Study of Patients with Cocaine- and/or Levamisole-induced Vasculitis and Vasculopathy

    Kevin Chevalier1, François Chasset2, Yoann Zerbib3, Pierre-André Jarrot4, Romain Muller4, Thomas Pires5, Saroumadi Adavane6, Didier Bessis7, Alban Deroux8, Vincent Descamps9, Fanny Domont10, Joëlle Faddoul10, Pierre-Edouard gavand11, Tiphaine Goulenok12, Baptiste Gramont13, Vincent Jachiet14, Gaëlle Leroux15, Matthieu Mahevas16, Julie Merindol17, Loïc Meudec18, Martin Michaud19, Morgane Mourguet20, Héloïse Munos pons21, Yann Nguyen22, Bénédicte Oules23, Thomas Papo24, Jacques Pouchot25, Sébastien Rivière14, Oscar Robert26, Charles ronsin27, Benjamin Rossi28, Delphine Staumont-salle29, Benjamin Terrier30, Nathalie Tieule31, Vollmer Olivier32, Pierre Wolkenstein33, Xavier Puéchal34, Jean-David Bouaziz35, Nicolas Dupin23, Gilles Peytavin36, Jean-Claude Alvarez37, Luc Mouthon38 and Alexis Régent34, 1Department of Internal Medicine, National Reference Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Université Paris Cité, Paris, France, Paris, France, 2Dermatology, Hôpital Tenon, Paris, France, 3Medical Intensive Care Unit and MP3CV-EA7517, Amiens University Hospital, Amiens, France, Amiens, France, 4Service de Médecine Interne et Immunologie Clinique, Hôpital de La Conception, Marseille, Marseille, France, 5Department of Internal Medicine, CHU Bordeaux, Bordeaux, France., Bordeaux, France, 6Service de Cardiologie, Hôpitaux Saint-Antoine and Tenon, AP-HP, 75012 Paris, France., Paris, France, 7Department of Dermatology and Reference Center for Rare Skin Diseases (MAGEC), Saint-Eloi Hospital, University of Montpellier and INSERM U1058, Montpellier, France., Montpellier, France, 8Clinique Universitaire de Médecine Interne, Department of Internal Medicine, Grenoble University Hospital, Grenoble, France, 9Department of Dermatology, APHP, Bichat Hospital, Paris, France., Paris, France, 10AP-HP. Centre de Référence des Maladies Auto-Immunes Systémiques Rares, Centre de Référence des Maladies Auto-Inflammatoires et de l'Amylose Inflammatoire, F-75013 Paris, France., Paris, France, 11Department of Internal Medicine, Clinique Rhena, Strasbourg, France., Strasbourg, France, 12Assistance Publique Hôpitaux de Paris, Paris, France, 13Internal Medicine Departement, Saint Etienne, Saint Etienne, France, 14Service de médecine interne, AP-HP, Hôpital Saint Antoine, Sorbonne Universite, Paris, France., Paris, France, 15Service de Médecine Interne, AP-HP Hôpital Pitié-Salpêtrière, Paris, France., Paris, France, 16Department of Internal Medicine, APHP, Mondor Hospital, Paris, France., Créteil, France, 17Internal Medicine Department, University Hospital of Nice, Côte d'Azur University, Nice, Provence-Alpes-Côte d'Azur, France., Nice, France, 18Department of Rheumatology, Université Paris-Saclay, Hôpital Bicêtre, Assistance Publique-Hôpitaux de Paris, Le Kremlin Bicêtre, France., Kremlin Bicêtre, France, 19Department of Internal Medicine, Clinique Saint-Exupery, Toulouse, France., Toulouse, France, 20service de médecine interne CHU Toulouse RANGUEIL, Toulouse, France, 21Department of Internal Medicine, Saint-Etienne University Hospital, Saint-Etienne, France., Saint Etienne, France, 22Université Paris Saclay, Clichy, Ile-de-France, France, 23Dermatology Department, Cochin Hospital, Paris, France., Paris, France, 24Université Paris Cité, Paris, France, 25Service de médecine Interne, Centre National de Référence des syndromes drépanocytaires majeurs de l'adulte, AP-HP, Hôpital Européen Georges Pompidou, Paris, France, Paris, France, 26Groupe Hospitalier Pitié Salpêtrière, Assistance Publique Hopitaux de Paris, Service de Pneumologie et Réanimation Médicale, Paris, France; [email protected]., Paris, France, 27cHD Vendée, La Roche sur Yon, La Roche sur Yon, France, 28Service de médecine interne, maladies infectieuses, Centre hospitalier intercommunal de Robert Ballenger, Aulnay-sous-bois, France., Aulnay-sous-bois, France, 29Service de dermatologie, CHU de Lille, université de Lille, 59000 Lille, France., Lille, France, 30Service de Médecine interne, Hôpital Cochin, AP-HP, Paris, Ile-de-France, France, 31Rhumatologie, Centre Hospitalier Universitaire Nice, Hôpital Pasteur, Nice, France, 32Department of Immunology and Internal Medicine, Strasbourg University Hospital, Strasbourg, France., Strasbourg, France, 33Department of Dermatology, National Referral Center for Neurofibromatosis, Henri Mondor University Hospital, Assistance Publique- Hôpitaux de Paris, Creteil, France., Créteil, France, 34National Referral Center For Rare Systemic Autoimmune Diseases, Paris, France, 35Dermatology, Hopital Saint-Louis, Paris, Île-de-France, France., Paris, France, 36Service de Pharmacologie, Université Paris Cité, INSERM, IAME, UMR 1137, AP-HP, Hôpital Bichat-Claude Bernard, Paris, France., Paris, France, 37Service de Pharmacologie‑Toxicologie, Hôpital Raymond Poincaré, Groupe Hospitalier Universitaires AP-HP.Paris-Saclay, Garches, 92380, France, Paris, France, 38Service de Médecine Interne, Centre de Référence Maladies Systémiques Autoimmunes et Autoinflammatoires Rares d'Ile de France de l’Est et de l’Ouest, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France

    Background/Purpose: Levamisole, an imidazothiazole formerly used as an anthelmintic, is also used as a cutting agent to enhance the effects and duration of cocaine. In…
  • Abstract Number: 0731 • ACR Convergence 2024

    Differentiating Primary Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis from Secondary Forms

    Adil Vural1, Kinanah Yaseen2, Cassandra Calabrese3 and Adam Brown4, 1Cleveland Clinic, Avon, OH, 2Cleveland Clinic, Cleveland, OH, 3Cleveland Clinic Foundation, Cleveland Heights, OH, 4Cleveland Clinic Foundation, Cleveland, OH

    Background/Purpose: ANCA associated vasculitis (AAV) is a severe autoimmune disorder with substantial morbidity and mortality. Establishing the diagnosis might be challenging due to the existence…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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