ACR Meeting Abstracts

ACR Meeting Abstracts

  • Home
  • Meetings Archive
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018 ACR/ARHP Annual Meeting
    • 2017 ACR/ARHP Annual Meeting
    • 2017 ACR/ARHP PRSYM
    • 2016-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • Register
    • View and print all favorites
    • Clear all your favorites
  • Meeting Resource Center

Abstracts tagged "ANA"

  • Abstract Number: 2712 • 2018 ACR/ARHP Annual Meeting

    Evaluation of Longitudinal Outcomes in Scleroderma Patients with Negative Immunofluorescent Anti-Nuclear Antibodies

    Mayce Haj-Ali1, Derek Jones2, Sean McNish3, Sarah Stupp3, Marissa Mangini3 and Victoria Shanmugam4, 1Department of Medicince, The George Washington University School of Medicine and Health Sciences, Washington, DC, 2The George Washington University, Washington, DC, 3The George Washington University School of Medicine and Health Sciences, Washington, DC, 4Rheumatology, The George Washington University, Washington, DC

    Background/Purpose: Systemic Sclerosis (SSc) is an autoimmune disease characterized by inflammation, fibrosis, and vasculopathy. Historical data indicates approximately 90% of patients with SSc test positive…
  • Abstract Number: 2578 • 2017 ACR/ARHP Annual Meeting

    RAB4A Protects from Antinuclear Antibody Production and Nephritis in the Pristane-Induced Model of SLE

    Gourav Choudhary1, Nick Huang2, Thomas Winans3, Ryan Kelly4, Sarah Blair3, Miguel Beckford3 and Andras Perl2, 1Department of Biochemistry and Mol. Biology, SUNY Upstate Medical University, Syracuse, NY, 2Medicine, SUNY Upstate Medical University, Syracuse, NY, 3SUNY Upstate Medical University, Syracuse, NY, 4SUNY, Syracuse, NY

    Background/Purpose: Systematic lupus erythematosus (SLE) is a multisystem chronic inflammatory disease characterized by circulating antinuclear autoantibodies and dysfunction of B cells, T cells, and dendritic…
  • Abstract Number: 43 • 2017 ACR/ARHP Annual Meeting

    Regulation of TLR7 Signalling By UBE2L3 Dependent Linear Ubiquitination Explains Dimethyl Fumarate Suppression of Autoreactive B Cell Development in SLE

    Daniele Mauro1, Victoria Tsang2, Isabelle A. Clayton-Lucey3, Sara Pagani2, Farah Alam2, Elena Pontarini2, Alessandra Nerviani2, Angela Pakozdi4, Andrea Cove-Smith4, Ravindra Rajakariar4, Debasish Pyne4, Timothy J Vyse5, Costantino Pitzalis2 and Myles J. Lewis4,6, 1Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London, School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom, 2Experimental Medicine & Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, United Kingdom, 3Experimental Medicine & Rheumatology, William Harvey Research Institute, Queen Mary University of London, EC1M 6BQ, United Kingdom, 4Barts Lupus Centre, Barts Health NHS Trust, London, United Kingdom, 5Division of Genetics and Molecular Medicine, King's College London, Guy's Hospital, London, United Kingdom, 6Rheumatology, Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London, School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

    Background/Purpose: A single risk haplotype spanning UBE2L3 is strongly associated with SLE and multiple autoimmune diseases. The E2 ubiquitin-conjugating enzyme UBE2L3 regulates TNFα and CD40…
  • Abstract Number: 198 • 2017 ACR/ARHP Annual Meeting

    The Impact of Electronic Consults (E-Consults) on Positive ANA Referrals in a Veteran Population

    Veena Patel1,2, Diana Stewart2,3 and Molly Horstman1,2,4, 1Internal Medicine, Baylor College of Medicine, Houston, TX, 2Internal Medicine, Michael E. DeBakey VA Medical Center, Houston, TX, 3Internal Medicine and Pediatrics, Baylor College of Medicine, Houston, TX, 4Center for Innovations in Quality, Effectiveness and Safety (iQUEST), Houston, TX

    Background/Purpose: Referrals to rheumatology for positive ANA in the absence of clinical signs and symptoms is a common practice, which may lead to unnecessary resource…
  • Abstract Number: 476 • 2017 ACR/ARHP Annual Meeting

    Novel Interaction between Anti-Citrulline Monoclonal Antibodies and Apoptotic Cells Is Mediated through Citrullinated Nuclear Antigens

    Katy A. Lloyd1, Peter Sahlström2, Johanna Steen1, Philip J. Titcombe3,4, Diana Zhou1, Christina Lundqvist5, Olov Ekwall6,7, Jimmy Ytterberg1, Johan Rönnelid8, Daniel L. Mueller3, Lars Klareskog1, Vivianne Malmström1 and Caroline Grönwall9, 1Dept. of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, 2Dept. of Medicine, Rheumatology Unit, Karolinska Institutet, Stockholm, Sweden, 3Dept. of Medicine, University of Minnesota Medical School, Minneapolis, MN, 4Dept. of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Sweden, Sweden, 5Dept. of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden, 6Dept. of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy University of Gothenburg, Göteborg, Sweden, 7Dept of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden, 8Department of Immunology Genetics and Pathology, Uppsala University, Uppsala, Sweden, 9Dep. of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

    Background/Purpose: Anti-citrullinated protein antibodies (ACPA) display broad cross-reactivities and target proteins including a-enolase, filaggrin, vimentin, fibrinogen, and histones. However, every monoclonal ACPA has a distinct…
  • Abstract Number: 559 • 2017 ACR/ARHP Annual Meeting

    Performance of Multiple Platforms for Autoantibody Testing in Sjogren’s Syndrome

    Astrid Rasmussen1, Kiely Grundahl2, Lida Radfar3, C. Erick Kaufman4, David M. Lewis5, Barbara M. Segal6, Nelson L. Rhodus7, Harini Bagavant1, Umesh Deshmukh8, Christopher J Lessard8, R. Hal Scofield1 and Kathy L. Sivils1, 1Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 2Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma CIty, OK, 3Department of Oral Diagnosis and Radiology, University of Oklahoma College of Dentistry, Oklahoma City, OK, 4College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 5Department of Oral Pathology, University of Oklahoma College of Dentistry, Oklahoma City, OK, 6Rheumatology, Hennepin County Medical Center, Minneapolis, MN, 7Department of Diagnostic and Biological Sciences, University of Minnesota School of Dentistry, Minneapolis, MN, 8Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK

    Background/Purpose: The research classification and clinical diagnosis of SjšgrenÕs syndrome (SS) relies heavily on the detection of autoantibodies against Ro/SSA and La/SSB, particularly in the…
  • Abstract Number: 673 • 2017 ACR/ARHP Annual Meeting

    Cell Bound Complement Activation Products Distinguish Systemic Lupus Erythematosus from Other Diseases Among Patients with High Antinuclear Antibody Titers and Normal Complement

    Daniel J. Wallace1, Elena Massarotti2, Rosalind Ramsey-Goldman3, Christopher E. Collins4, Anca Askanase5, Jill P. Buyon6, Richard Furie7, Sonali Narain7, Amit Saxena8, Kenneth C. Kalunian9, Cristina Arriens10, Chaim Putterman11, John Conklin12, Roberta Alexander12, Claudia Ibarra12, Tyler O'Malley13, Tarun Chandra14, Joseph Ahearn15, Susan Manzi16, Arthur Weinstein17 and Thierry Dervieux12, 1Cedars-Sinai Medical Center, UCLA, Los Angeles, CA, 2Brigham and Women's Hospital, Boston, MA, 3FSM, Northwestern University, Chicago, IL, 4Rheumatology, MedStar Washington Hospital Center, Washington, DC, 5Department of Medicine, Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, 6Rheumatology, NYU Langone Medical Center, New York, NY, 7Northwell Health, Great Neck, NY, 8NYU Langone Medical Center, New York, NY, 9Division of Rheumatology, Allergy and Immunology, UCSD School of Medicine, La Jolla, CA, 10Arthritis & Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 11Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, USA, Bronx, NY, 12Exagen Diagnostics, Inc., Vista, CA, 13Research and Development, Exagen Diagnostics, Inc., Vista, CA, 14EmpiriQA LLC, Long Grove, IL, 15Lupus Center of Excellence, West Penn Allegheny Health System, Pittsburgh, PA, 16Medicine, Allegheny Health Network, Pittsburgh, PA, 17Rheumatology, MedStar Washington Hospital Center/Georgetown University Medical Center, Washington, DC

    Background/Purpose: Patients are often referred to the rheumatologist because of elevated anti-nuclear antibody (ANA) titers. We sought to evaluate the association of cell bound complement…
  • Abstract Number: 700 • 2017 ACR/ARHP Annual Meeting

    Variability in Method of Testing for Antinuclear Antibodies (ANA): A Survey of Participants in the College of American Pathologist’s (CAP) Proficiency Testing Program

    Stanley J. Naides1, Jonathan Genzen2, Gyorgy Abel3, Christine Bashleben4 and Mohammad Qasim Ansari5, 1Immunology, Quest Diagnostics Nichols Institute, San Juan Capistrano, CA, 2ARUP Laboratories Inc, Salt Lake City, UT, 3Department of Pathology and Laboratory Medicine, Lahey Clinic Burlington, Burlington, VT, 4College of American Pathologists, Northfield, IL, 5Department of Pathology and Laboratory Medicine, Louis Stokes VAMC, Cleveland, OH

    Background/Purpose: A 2010 American College of Rheumatology position paper designated indirect immunofluorescence assay (IFA) on HEp-2 cells the “gold standard” for ANA testing and that…
  • Abstract Number: 1097 • 2017 ACR/ARHP Annual Meeting

    Investigating Opportunities for Cost Conscious Care: A Review of Physician Practice in Ordering Anti-Nuclear Antibody Testing at an Academic Community Hospital

    Hrudya Abraham, Jorge Espinal and Sindhu Joseph, Internal Medicine, MacNeal Hospital, Berwyn, IL

    Background/Purpose: More than 94,000 ANA tests are performed each year resulting in an estimated cost of 2.24 million dollars annually. The American College of Rheumatology…
  • Abstract Number: 1047 • 2016 ACR/ARHP Annual Meeting

    Negative Results of Antinuclear Antibody (ANA) Testing in Clinical Trials of Systemic Lupus Erythematosus (SLE) May be Due to Assay Variability

    David Pisetsky1, Dana Thompson1, Joseph Wajdula2, Annette Diehl2 and Sudhakar Sridharan3, 1Duke University Medical Center and Durham VAMC, Durham, NC, 2Global Product Development, Pfizer Inc, Collegeville, PA, 3PPD Inc, Rockville, MD

    Background/Purpose:   SLE clinical trials typically require that patients have either a positive ANA serology at a central laboratory during screening or have prior positive…
  • Abstract Number: 1049 • 2016 ACR/ARHP Annual Meeting

    High Titer ANA Not Necessarily a Valid Criterion for Lupus – Proposal of a Modification to the Criteria for Classification of SLE

    Luis E C Andrade1, Jan Damoiseaux2, Minoru Satoh3, Edward K.L. Chan4, Mônica Prado5, Henrique Mariz6, Renan Agustinelli7 and Alessandra Dellavance8, 1Pediatric Rheumatology Unit, Universidade Federal de São Paulo, São Paulo, Brazil, 2Central Diagnostic Laboratory, Maastricht University Medical Center, Maastricht, Netherlands, 3Department of Clinical Nursing, School of Health Sciences, University of Occupational and Environmental Health, Kitakyushu, Japan, 4Dept of Oral Biology, University of Florida, Gainesville, FL, 5Rheumatology, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil, 6Internal Medicine, Hospital das Clínicas - UFPE, Recife, Brazil, 7Rheumatology Division, Escola Paulista de Medicina, São Paulo, Brazil, 8Research and Development Department, Fleury Medicine and Health Laboratories, São Paulo, Brazil

    Background/Purpose:  A positive ANA test is one of ACR Revised Criteria for Classification of SLE, as well as the SLICC classification. The ANA test provides…
  • Abstract Number: 1346 • 2016 ACR/ARHP Annual Meeting

    Factors That Influence Therapy in Patients with Undifferentiated Connective Tissue Disease

    Diana P. Pena1 and Anca D. Askanase2, 1Rheumatology, Universidad Militar Nueva Granada, Bogotá, Colombia, 2Department of Medicine, Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY

    Background/Purpose: To compare clinical and immunological characteristics in patients with undifferentiated connective tissue disease (UCTD) treated with hydroxycholoroquine (HCQ) in a large academic clinical practice.…
  • Abstract Number: 1769 • 2016 ACR/ARHP Annual Meeting

    Fatigue in Anti-Nuclear Antibody Positive Individuals with Insufficient Criteria to Diagnose a Systemic Autoimmune Rheumatic Disease

    Rawad Nori1, Babak Noamani2, Dennisse Bonilla2, Larissa Lisnevskaia3, Earl Silverman4, Arthur Bookman5, Sindhu R. Johnson1, Carolina Landolt-Marticorena2 and Joan Wither2, 1Rheumatology, Mount Sinai Hospital and University Health Network, Toronto, ON, Canada, 2Krembil Research Institute, University Health Network, Toronto, ON, Canada, 3Lakeridge Health Services, Oshawa, ON, Canada, 4University of Toronto, Toronto, ON, Canada, 5Rheumatology, University Health Network, Toronto, ON, Canada

    Background/Purpose:  Fatigue is a common symptom of Systemic Autoimmune Rheumatic Disease (SARD) and has been proposed to result from the elaboration of pro-inflammatory factors in…
  • Abstract Number: 1874 • 2016 ACR/ARHP Annual Meeting

    Low Rate of Progression in Cases of Isolated Raynaud’s Phenomenon Screened By Nailfold Videocapillaroscopy and Antinuclear Antibody Status Supports Negative Predictive Value of These Tests

    Louise Parker1, Kevin Howell2, Voon H. Ong3 and Christopher P.Denton4, 1Centre for Rheumatology and Connective Diseases, UCL Medical School and Royal Free Hosp, London, United Kingdom, 2Institute of Immunity and Transplantation, University College London, Royal Free Campus, London, United Kingdom, 3Rheumatology, UCL Division of Medicine, London, United Kingdom, 4Centre of Rheumatology and Connective Tissue Diseases, University College London, London, United Kingdom

    Background/Purpose:   Raynaud’s phenomenon is common but can progress to definite connective tissue disease. We have observed long term follow up of an unselected consecutive…
  • Abstract Number: 2147 • 2016 ACR/ARHP Annual Meeting

    Lack of Pro-Inflammatory Cyto/Chemokines in ANA+ Individuals with Insufficient Criteria for a Diagnosis of Systemic Autoimmune Rheumatic Disease

    Waleed Hafiz1, Nan-Hua Chang2, Babak Noamani3, Dennisse Bonilla3, Larissa Lisnevskaia4, Earl Silverman5, Arthur Bookman6, Sindhu R. Johnson7, Carolina Landolt-Marticorena3 and Joan Wither3, 1Rheumatology, University of Toronto, Toronto, ON, Canada, 2Genetics and Development, Krembil Research Institute, University Health Network, Toronto, ON, Canada, 3Krembil Research Institute, University Health Network, Toronto, ON, Canada, 4Lakeridge Health Services, Oshawa, ON, Canada, 5Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 6Rheumatology, University Health Network, Toronto, ON, Canada, 7Rheumatology, Mount Sinai Hospital and University Health Network, Toronto, ON, Canada

    Background/Purpose: Patients with Systemic Autoimmune Rheumatic Disease (SARD) often have a prolonged pre-clinical phase during which they are anti-nuclear antibody (ANA) positive but lack clinical…
  • « Previous Page
  • 1
  • 2
  • 3
  • 4
  • 5
  • Next Page »
Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

ACR Convergence: Where Rheumatology Meets. All Virtual. November 5-9.

ACR Pediatric Rheumatology Symposium 2020

© COPYRIGHT 2021 AMERICAN COLLEGE OF RHEUMATOLOGY

Wiley

  • Home
  • Meetings Archive
  • Advanced Search
  • Meeting Resource Center
  • Online Journal
  • Privacy Policy
  • Permissions Policies
This site uses cookies: Find out more.