Abstracts tagged "Allopurinol"

Abstract Number: L10 • 2014 ACR/ARHP Annual Meeting
Lesinurad, a Novel Selective Uric Acid Reabsorption Inhibitor, in Two Phase III Clinical Trials: Combination Study of Lesinurad in Allopurinol Standard of Care Inadequate Responders (CLEAR 1 and 2)
Kenneth G. Saag¹, Scott Adler², Nihar Bhakta³, Maple Fung³, Jeff Kopicko³, Chris Storgard³ and Thomas Bardin⁴, ¹Immunology & Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, ²AstraZeneca Pharmaceuticals, Wilmington, DE, ³Ardea Biosciences, Inc., San Diego, CA, ⁴Clinique de Rhumatologie. Service de Rhumatologie. Centre Viggo Petersen., Hôpital Lariboisière, Paris, France
Background/Purpose: Inadequate response to allopurinol monotherapy is common. Lesinurad (RDEA594) is a selective uric acid reabsorption inhibitor (SURI) under investigation for treatment of gout in…