Abstract Number: 2199 • 2016 ACR/ARHP Annual Meeting
Peri-Aortic Adipose Tissue Volume Is Directly Associated with Fat Accumulation in Adjacent Trunk Muscles Independent of Other Fat Depots: The Framingham Study
Background/Purpose: Multidetector CT abdominal imaging measured PAAT volume (cm3), as well as cross-sectional area (mm2) and attenuation (HU), a marker of fat content, of the…Abstract Number: 2572 • 2016 ACR/ARHP Annual Meeting
Study of Two Biomarkers of Biological Age in the Blood of Patients with Rheumatoid Arthritis
Background/Purpose: Accelerated biological aging of blood cells could contribute to the pathogenesis of RA. However, biological age has multiple facets, some as epigenetic aging not…Abstract Number: 3041 • 2016 ACR/ARHP Annual Meeting
Age-Related Defects in the Immune System of Patients with GCA
Background/Purpose: Advancing age is the strongest risk factor for GCA, a disease that exclusively affects individuals >50 years of age. The immune system undergoes dramatic…Abstract Number: 2643 • 2015 ACR/ARHP Annual Meeting
Decreased Pain Level with Aging Leads to Underestimation of Disease Activity in Rheumatoid Arthritis
Background/Purpose: Rheumatoid arthritis (RA) is most prevalent in those who are 60 years of age or older. It has not been clearly established whether…Abstract Number: 326 • 2015 ACR/ARHP Annual Meeting
Older Adults without Extreme Obesity Are at Highest Risk for Accelerated Knee Osteoarthritis
Background/Purpose: Accelerated knee osteoarthritis (AKOA) may be a unique subset of knee osteoarthritis (KOA). AKOA is more common among those who are older, overweight, or…Abstract Number: 1533 • 2015 ACR/ARHP Annual Meeting
Age Related Disability in Daily Life Should be Considered in Older Than Sixty-Five-Year-Old Rheumatoid Arthritis Patient
Background/Purpose: In treating rheumatoid arthritis (RA), patient’s activity in daily life (ADL) is extremely important factor, because RA is chronic inflammatory disease that leads discomfort…Abstract Number: 1593 • 2015 ACR/ARHP Annual Meeting
Telomere Length and Cardiovascular Risk in Rheumatoid Arthritis
Background/Purpose: Telomeres protect against DNA damage and shorten with each cell division; their length may be a marker of cardiovascular and overall biological aging. Patients…Abstract Number: 1663 • 2015 ACR/ARHP Annual Meeting
Influence of Age and Renal Impairment on Pharmacokinetics of Filgotinib (GLPG0634), a Selective JAK1 Inhibitor
Background/Purpose: Filgotinib is an oral, selective Janus kinase 1 (JAK1) inhibitor combining clinical efficacy and a rapid onset of action with a good safety profile…Abstract Number: 1966 • 2015 ACR/ARHP Annual Meeting
Active PMR and GCA Is Associated with Changes in Monocyte Subset Composition
Background/Purpose: Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are two closely related syndromes affecting older people. Proinflammatory cytokine IL-6 is found increased in both…Abstract Number: 2477 • 2015 ACR/ARHP Annual Meeting
What Older Adults with Restricting Back Pain Worry about: Deteriorating Function, Reliance on Others, Distrust of Medications
Background/Purpose: Although back pain is the most common type of pain disorder reported by older adults, its impact on the daily life of older adults…Abstract Number: 2857 • 2014 ACR/ARHP Annual Meeting
Restricting Back Pain Is Strongly Associated with Disability in Community-Living Older Persons over the Course of 13 Years
Background/Purpose: Although back pain is common and costly, few longitudinal studies have evaluated the association between back pain severe enough to restrict activity [hereafter referred…Abstract Number: 1872 • 2014 ACR/ARHP Annual Meeting
Gout in Older Adult
Background/Purpose: To evaluate whether traditional and genetic risk factors in middle-aged members of a longitudinal population-based cohort predict the onset of gout in older age.…Abstract Number: 1737 • 2014 ACR/ARHP Annual Meeting
Altered Phenotype and Function of Senescent Regulatory T Cells in Rheumatoid Arthritis
Background/Purpose Immunosenescence accompanied by accumulation of senescent T cells is a hallmark feature in the pathogenesis of rheumatoid arthritis (RA). Here we characterize a novel senescent…Abstract Number: 1379 • 2014 ACR/ARHP Annual Meeting
Studies on Ageing and the Severity of Radiographic Joint Damage in Rheumatoid Arthritis
Background/Purpose: The Western population is getting older; consequently the proportion of elderly persons presenting with Rheumatoid Arthritis (RA) is increasing. We studied whether age is…Abstract Number: 1220 • 2014 ACR/ARHP Annual Meeting
Higher Inflammatory Response in Elderly Patients during Gout Attack
Higher inflammatory response in elderly patients during gout attack Background/Purpose Clinical experiences suggest that gout attacks in elderly patients are accompanied by stronger systemic inflammatory…
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