Abstracts tagged "Aging"

Abstract Number: 56 • 2013 ACR/ARHP Annual Meeting
Age-Related Loss Of The Transforming Growth Factor Beta Receptor ALK5 Precedes Osteoarthritis Development In Cartilage
Arjan van Caam¹, Esmeralda N. Blaney Davidson², Eva Thijssen¹, Wim B. van den Berg¹ and Peter M. van der Kraan¹, ¹Rheumatology Research and Advanced Therapeutics, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ²Rheumatology Research & Advanced Therapeutics, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
Background/Purpose: Osteoarthritis (OA) is the most common joint disease and (old) age is its main risk factor. One of OA's main hallmarks is degradation of…
Abstract Number: 28 • 2013 ACR/ARHP Annual Meeting
Differentiation, Activation, and Autoreactivity Of CD11c+ B Cells (ABCs)
Alice E. Wiedeman¹, Natalia V. Giltiay², Lena Tanaka³ and Keith B. Elkon³, ¹Immunology, University of Washington, Seattle, WA, ²Department of Immunology, Division of Rheumatology, University of Washington, Seattle, WA, ³Rheumatology, University of Washington, Seattle, WA
Background/Purpose: Recently, a population of CD11c+ age-associated B cells (ABCs) was identified in normal aged female mice. These cells could be expanded following activation by…
Abstract Number: 132 • 2013 ACR/ARHP Annual Meeting
Relation Of Age With Symptom Severity and Quality Of Life In Patients With Fibromyalgia
Juan Jiao^1,2, Ann Vincent³, Connie A. Luedtke⁴, Stephen Cha⁵ and Terry H. Oh⁶, ¹Rheumatology, Guang'anmen Hospital , China Academy of Chinese Medical Sciences, Beijing, China, ²Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, ³General Internal Medicine, Mayo Clinic, Rochester, MN, ⁴Department of Nursing, Mayo Clinic, Rochester, MN, ⁵Health Sciences Research, Mayo Clinic, Rochester, MN, ⁶Physical Medicine & Rehabilitation, Mayo Clinic, Rochester, MN
Background/Purpose: The relationship of age and fibromyalgia symptom severity and quality of life (QOL) is still debated. Reports range from no differences between patients younger…
Abstract Number: 72 • 2013 ACR/ARHP Annual Meeting
Autophagy Changes During Aging: A Study In GFP-LC3 Mice
Beatriz Carames¹, William B. Kiosses², Merissa Olmer³ and Martin Lotz⁴, ¹Cartilage Biology Group. Rheumatology Division, INIBIC–A Coruña, SPAIN, A Coruña, Spain, ²The Scripps Research Institute, La Jolla, CA, ³The Sripps Research Institute, La Jolla, CA, ⁴The Scripps Research Institute, La Jolla, USA, La Jolla, CA
Background/Purpose: Aging is a main risk factor for osteoarthritis (OA), the most prevalent musculoskeletal disorder. Aging-associated changes in autophagy, an essential cellular homeostasis mechanism, have…
Abstract Number: 2909 • 2013 ACR/ARHP Annual Meeting
2010 Medical Care Expenditures Among US Adults With Arthritis
Miriam Cisternas¹, Louise Murphy², David Pasta³, Edward H. Yelin⁴ and Charles G. Helmick⁵, ¹MGC Data Services, Carlsbad, CA, ²Division of Population Health, CDC, Atlanta, GA, ³DMA Corporation, Palo Alto, CA, ⁴Medicine, UC San Francisco, San Francisco, CA, ⁵National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA
Background/Purpose: Using data from the 2010 Medical Expenditure Panel Survey (MEPS), we estimated total and arthritis-attributable medical care expenditures among US adults age 18 years…
Abstract Number: 2854 • 2013 ACR/ARHP Annual Meeting
Restricting Back Pain and Subsequent Mobility Disability In Community-Living Older Persons
Una E. Makris¹, Liana Fraenkel², Ling Han³, Linda Leo-Summers³ and Thomas M. Gill⁴, ¹Rheumatology, UT Southwestern Medical Center, VA Medical Center, Dallas, TX, ²Medicine, Section of Rheumatology, Yale University School of Medicine, Veterans Affairs Connecticut Healthcare System, New Haven, CT, ³Internal Medicine, Department of Medicine, New Haven, CT, ⁴Internal Medicine, Section of Geriatrics, Yale University, New Haven, CT
Background/Purpose: Although back pain is common and costly, few longitudinal studies have evaluated the association between back pain, severe enough to restrict activity (hereafter referred…

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