Abstracts tagged "Adhesion molecules and inflammation"

Abstract Number: 1779 • 2012 ACR/ARHP Annual Meeting
The Loss of Syndecan-4 Aggravates Inflammatory Colitis in Mice
Athanasios Stratis¹, Dominik Bettenworth², Mareike Fröhling¹, Peter Paruzel¹, Adelheid Korb-Pap¹, Corinna Wehmeyer¹, Berno Dankbar¹, Frank Echtermeyer³, Andreas Lügering⁴ and Thomas Pap¹, ¹Institute of Experimental Musculoskeletal Medicine (IEMM), University Hospital Muenster, Muenster, Germany, ²Department of Medicine B University Hospital Münster, University Hospital Muenster, Muenster, Germany, ³Dept. of Anaesthesiology and Intensive Care Medicine, University Hospital Hannover, Hanover, Germany, ⁴Department of Medicine B University of Münster, MVZ Portal 10, Münster, University Hospital Muenster, Muenster, Germany
Background/Purpose: Syndecan-4 (sdc4) is a transmembrane heparan sulfate proteoglycan. Several studies have implicated sdc4 in cell-matrix adhesion, cell migration, differentiation, proliferation and play an important…