Abstracts tagged "Activity score"

Abstract Number: 2618 • 2012 ACR/ARHP Annual Meeting
Lupus Disease Activity Severely Impairs Pandemic Influenza A/H1N1 Vaccine Immune Response in Patients without Therapy
Eduardo F. Borba¹, Sandra G. Pasoto¹, Ana L. Calich¹, Ricardo Fuller¹, Vilma S.T. Viana¹, Margareth Vendramini¹, Joao Miraglia², Maria A. Ishida³ and Eloisa Bonfa⁴, ¹Rheumatology Division, University of Sao Paulo, Sao Paulo, Brazil, ²Instituto Butantan, Fundação Butantan, São Paulo, Brazil, ³Instituto Adolfo Lutz, São Paulo, Brazil, ⁴Rheumatology Division, University of São Paulo, Sao Paulo, Brazil
Background/Purpose: To determine the influence of disease activity without the effect of drugs in pandemic 2009 influenza A (H1N1) vaccine immune response in untreated systemic…
Abstract Number: 402 • 2012 ACR/ARHP Annual Meeting
Discordant Inflammatory Markers in Veterans with Rheumatoid Arthritis: Baseline Characteristics and Relationship with Disease Activity
Rebecca Belsom¹, Archana Jain¹, Jeffrey R. Curtis², Shuo Yang³, Ted R. Mikuls⁴, Lang Chen⁵ and Angelo L. Gaffo⁶, ¹Rheumatology, University of Alabama, Birmingham, AL, ²Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ³Clinical Immunology/Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁴Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, ⁵Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁶Medicine, Birmingham VA Medical Center and University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Discrepancies between erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) elevations with clinical disease activity frequently occur in rheumatoid arthritis (RA) patients and may…
Abstract Number: 2348 • 2012 ACR/ARHP Annual Meeting
Plasma Fibrinogen Better Identifies Persistent Disease Activity in Polymyalgia Rheumatica Than Either ESR or CRP
EM McCarthy¹, Paul A. MacMullan¹, S. Al-Mudhaffer¹, Anne M. Madigan¹, S. Donnelly¹, C. J. McCarthy¹, Dermot Kenny², Eamonn Molloy³ and G M. McCarthy¹, ¹Rheumatology, Mater Misericordiae University Hospital, Dublin 7, Ireland, ²Molecular and Cellular Therapeutics, RCSI, Dublin 2, Ireland, ³Rheumatology, Dublin Academic Medical Centre, St. Vincent's University Hospital, Dublin, Ireland
Background/Purpose: In PMR careful tailoring of the glucocorticoid dosage to the patients needs is crucial to avoid the risk of treatment-related adverse effects and the…
Abstract Number: 319 • 2012 ACR/ARHP Annual Meeting
Gamma Interferon-Induced Protein-10 (IP-10) As a Potential Biomarker for Disease Activity in Pediatric Localized Scleroderma
Katherine Kurzinski¹, Carol A. Feghali-Bostwick², Christina Kelsey¹, Kelsey Magee³ and Kathryn S. Torok⁴, ¹Pediatric Rheumatology, Univ of Pittsburgh Med Ctr, Pittsburgh, PA, ²Medicine, University of Pittsburgh, Pittsburgh, PA, ³Pediatric Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁴Pediatric Rheumatology, Scleroderma Center of Pittsburgh, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA
Background/Purpose: Pediatric localized scleroderma (LS) is an autoimmune disease affecting the skin and underlying tissue. Cutaneous findings assist in categorizing the patients into active or…
Abstract Number: 2121 • 2012 ACR/ARHP Annual Meeting
A Multi-Biomarker Disease Activity (VECTRA™ DA Algorithm) Score Reflects Clinical Disease Activity and Structural Changes in Rheumatoid Arthritis Patients Treated with Tocilizumab
Yoshiya Tanaka¹, Kentaro Hanami², Hisashi Tasaka¹, Shunsuke Fukuyo¹, Douglas J. Haney³, Nadine Defranoux³, Rebecca Bolce³, Guy Cavet³, David Chernoff³, Kunihiro Yamaoka¹, Kazuyoshi Saito¹ and Shintaro Hirata¹, ¹The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, ²The First Department of Internal Medicinei, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, ³Crescendo Bioscience Inc., South San Francisco, CA
Background/Purpose: The multi-biomarker disease activity (MBDA) score assessed with 0.2 mL serum has been reported as a novel composite disease activity index for patients with…
Abstract Number: 277 • 2012 ACR/ARHP Annual Meeting
Dyslipidemia in Juvenile Dermatomyositis: The Role of Disease Activity
Katia T. Kozu¹, Clovis Artur Silva², Eloisa Bonfa³, Adriana M. Sallum⁴, Rosa M.R. Pereira⁵, Vilma S. Viana⁶, Eduardo F. Borba⁷ and Lucia M. A. Campos⁴, ¹Pediatric Rheumatology Unit, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²Paediatric Rheumatology International Trials Organization (PRINTO), Istituto Giannina Gaslini, Genova, Italy, ³Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁴Pediatric Rheumatology Unit, Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, ⁵Rheumatology, University of São Paulo, São Paulo, Brazil, ⁶Rheumatology Division, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, ⁷Rheumatology Division, University of Sao Paulo, Sao Paulo, Brazil
Background/Purpose: Dyslipidemia has been infrequently investigated in pediatric population with autoimmune rheumatic diseases. However, lipid abnormalities in these diseases may occur due to multiple risk…
Abstract Number: 2008 • 2012 ACR/ARHP Annual Meeting
Initial Evaluation of a Localized Scleroderma (LS) Clinical Activity Measure
Suzanne C. Li¹, Kathryn S. Torok², Christina Kelsey³, Mara L Becker⁴, Fatma Dedeoglu⁵, Robert C. Fuhlbrigge⁶, Gloria C. Higgins⁷, Sandy D. Hong⁸, Maria F. Ibarra⁹, Ronald Laxer¹⁰, Thomas G. Mason II¹¹, Marilynn G. Punaro¹², Elena Pope¹³, C. Egla Rabinovich¹⁴ and Katie G. Stewart¹², ¹Pediatrics, Joseph M Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack, NJ, ²Pediatric Rheumatology, Scleroderma Center of Pittsburgh, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ³Pediatric Rheumatology, Univ of Pittsburgh Med Ctr, Pittsburgh, PA, ⁴Clinical Pharmacology and Rheumatology, Children's Mercy Hospital, Kansas City, MO, ⁵Division of Immunology, Boston Children's Hospital, Boston, MA, ⁶Pediatric Rheumatology, Childrens Hospital, Boston, MA, ⁷Pediatric Rheumatology Ohio State University, Nationwide Childrens Hosp, Columbus, OH, ⁸Pediatrics-Rheumatology, U of Iowa Children's Hosp, Iowa City, IA, ⁹Pediatric Rheumatolgy, Children's Mercy Hospital, Kansas City, MO, ¹⁰Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹¹Rheumatology, Mayo Clinic Rochester, Rochester, MN, ¹²Pediatric Rheumatology, Texas Scottish Rite Hospital, Dallas, TX, ¹³Dermatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹⁴Pediatric Rheumatology, Duke University Medical Center, Durham, NC
Background/Purpose: LS commonly causes severe morbidity for the growing child. Optimal therapy is not known and the lack of an agreed-upon standard for assessing disease…
Abstract Number: 128 • 2012 ACR/ARHP Annual Meeting
Quantitative Assessment of Synovitis in Patients with Rheumatoid Arthritis Using Fluorescence Optical Imaging
Valentin S. Schäfer¹, Wolfgang Hartung², Patrick Hoffstetter³, Jörn Berger⁴, Martina Müller⁵, Martin Fleck² and Boris P. Ehrenstein², ¹Rheumatology & Clinical Immunology, Asklepios Klinikum Bad Abbach, Bad Abbach, Germany, ²Rheumatology & Clinical Immunology, Asklepios Clinic Bad Abbach, Bad Abbach, Germany, ³Radiology, Asklepios Klinikum Bad Abbach, Bad Abbach, Germany, ⁴mivenion GmbH, Berlin, Germany, ⁵Clinic for Internal Medicine I, University Clinic Regensburg, Regensburg
Background/Purpose: To prospectively evaluate quantitative assessment of indocyanine green (ICG)-enhanced fluorescence optical imaging (FOI) for differentiation of synovitic from non-synovitic joints in patients suffering from…
Abstract Number: 1526 • 2012 ACR/ARHP Annual Meeting
Patient Reported Outcomes in ANCA-Associated Vasculitis. A Prospective Comparison Between Birmingham Vasculitis Activity Score and Routine Assessment of Patient Index Data 3
Osama ElSallabi¹, Joel A. Block¹ and Antoine Sreih², ¹Section of Rheumatology, Rush University Medical Center, Chicago, IL, ²Medicine/Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: ANCA-associated vasculitis (AAV) is a rare group of diseases comprising Granulomatosis with polyangiitis (Wegener’s; GPA), Microscopic Polyangiitis (MPA), and Churg-Strauss Syndrome (CSS). These diseases…
Abstract Number: 115 • 2012 ACR/ARHP Annual Meeting
Composite Ultrasound Score in Spondyloarthropathies
Maria L. Acosta Felquer¹, Cristian Quiroz², Santiago Ruta³, Javier Rosa⁴, Marina Scolnik², Leandro Ferreyra Garrott³, Ricardo Garcia-Monaco⁵ and Enrique R. Soriano⁶, ¹Internal Medicine, Rheumatology Section, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ²Internal Medicine, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ³Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁴Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁵Radiology and Imagenology Department, Hospital italiano de Buenos Aires, Buenos Aires, Argentina, ⁶Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina
Background/Purpose: A comprehensive ultrasound (US) scoring system which includes enthesitis tenosynovitis and synovitis for use in patients with spondyloarthropathies (SpA) is not yet available. The…
Abstract Number: 1358 • 2012 ACR/ARHP Annual Meeting
Performance of Remission Criteria and Activity Indices in Psoriatic Arthritis
Maria L. Acosta Felquer¹, Leandro Ferreyra Garrott², Erika Catay³, Josefina Marin⁴, Marina Scolnik⁵, Maria Victoria Garcia⁵, Santiago Ruta², Mirtha Sabelli⁶, Zaida Bedran⁶, Javier Rosa³, Luis J. Catoggio⁷ and Enrique R. Soriano⁷, ¹Internal Medicine, Rheumatology Section, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ²Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ³Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁴Internal Medicine, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁵Internal Services, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁶Rheumatology Section, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁷Internal Medicine, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM. Catoggio, Buenos Aires, Argentina
Background/Purpose: Remission criteria and activity indices used in rheumatoid arthritis (RA) are often applied in psoriatic arthritis (PsA). Although indices have been specifically developed for…
Abstract Number: 124 • 2012 ACR/ARHP Annual Meeting
Reliability of an Ultrasound Scoring Measure for Juvenile Localized Scleroderma (jLS)
Suzanne C. Li¹, Melissa S. Liebling², Andrea S. Doria³, Molly Dempsey-Robertson⁴, Carsten Hamer⁵, Sven Opitz⁵, Faridali Ramji⁶, Stephanie Edgerton⁶, Jose Jarrin³, Tanicka Kornyat², Michael Malone⁶, Arun Mohanta³, Shuzhen Zhang⁴ and Knut M. Wittkowski⁷, ¹Pediatrics, Joseph M Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack, NJ, ²Radiology, Hackensack University Medical Center, Hackensack, NJ, ³Diagnostic Imaging, Hospital for Sick Children, Toronto, ON, Canada, ⁴Radiology, Texas Scottish Rite Hospital, Dallas, TX, ⁵Radiology, Schon Klinik Hamburg Eilbek, Hamburg, Germany, ⁶Radiology, University of OK Health Science Center, Okc, OK, ⁷Center for Clinical and Translational Science, Rockefeller University, New York, NY
Background/Purpose: Although ultrasound (US) shows great potential for aiding assessment of LS disease activity, its use has been limited because both image acquisition and interpretation…
Abstract Number: 1297 • 2012 ACR/ARHP Annual Meeting
Tofacitinib and Adalimumab Achieve Similar Rates of Low Disease Activity in Rheumatoid Arthritis — Lack of Improvement in Disease Activity Score by 3 Months Predicts Low Likelihood of Low Disease Activity At 1 Year
Ronald F. van Vollenhoven¹, Sriram Krishnaswami², Birgitta Benda³, David Gruben⁴, Bethanie Wilkinson⁴, Charles A. Mebus⁴, Samuel H. Zwillich² and John Bradley², ¹Karolinska Institute, Stockholm, Sweden, ²Pfizer Inc, Groton, CT, ³Pfizer Inc., Collegeville, PA, ⁴Pfizer Inc., Groton, CT
Background/Purpose: Tofacitinib is a novel oral Janus kinase inhibitor being investigated as a targeted immunomodulator and disease-modifying therapy for RA. This post-hoc analysis of the…
Abstract Number: 76 • 2012 ACR/ARHP Annual Meeting
The Difference in Performance of DAS28 and RADAI During Pregnancy Might Explain Discrepancies Between Older and More Recent Studies On the Impact of Pregnancy On Rheumatoid Arthritis
Jan Naterop¹, Johanna M.W. Hazes² and Radboud J.E.M. Dolhain³, ¹Rheumatology, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands, Rotterdam, Netherlands, ²Rheumatology, Erasmus University Medical Center, Rotterdam, Netherlands, ³Rheumatology, Erasmus Medical Center, Rotterdam, Netherlands
Background/Purpose: Pregnancy is the only condition in which Rheumatoid Arthritis (RA) shows spontaneous remission. Both older and more recent studies showed improvement of disease activity,…

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