ACR Meeting Abstracts

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Abstracts tagged "Activity score"

  • Abstract Number: 2664 • 2012 ACR/ARHP Annual Meeting

    A Multi-Biomarker Disease Activity (VECTRA™ DA Algorithm) Score Reflects Clinical Disease Activity and Tracks Responses in Patients with Rheumatoid Arthritis Treated with Either Adalimumab, Etanercept, and Infliximab

    Shintaro Hirata1, Douglas J. Haney2, Guy Cavet2, Rebecca Bolce2, Wanying Li2, Nadine Defranoux2, David Chernoff2, Kunihiro Yamaoka1, Kazuyoshi Saito1 and Yoshiya Tanaka1, 1The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, 2Crescendo Bioscience Inc., South San Francisco, CA

    Background/Purpose : Anti-TNF therapy has become a standard therapeutic strategy for treatment of patients with rheumatoid arthritis (RA).  A validated multi-biomarker disease activity algorithm (MBDA) blood…
  • Abstract Number: 1044 • 2012 ACR/ARHP Annual Meeting

    Ultrasound Scores of Enthesitis and Dactylitis Do Not Correlate with Corresponding Clinical Findings in Psoriasis Arthritis

    Rusmir Husic1, Josef Hermann1, Judith Gretler2, Winfried B. Graninger3 and Christian Dejaco4, 1Rheumatology, Medical University Graz, Graz, Austria, 2Med Univ Klinik Graz, Auenbruggerplatz 15, Graz, Austria, 3Internal medicine/Rheumatology and Immunology, Medical University Graz, Graz, Austria, 4Rheumatology, Southend University Hospital, Westcliff-on-Sea, United Kingdom

    Background/Purpose: To compare sonography verified inflammation of entheses, tendons and joints with corresponding clinical findings in psoriasis arthritis (PsA) patients. Methods: Prospective study of 70 consecutive…
  • Abstract Number: 691 • 2012 ACR/ARHP Annual Meeting

    Characterization of Pro-Inflammatory Cytokines and Vitamin D Levels in a Lupus Cohort and Correlation with Disease Activity

    Rohan Willis1, Praveen Jajoria1, Brock E. Harper2, Emilio B. Gonzalez3, Michelle Petri4, Ehtisham Akhter5, Hong Fang4 and Silvia S. Pierangeli1, 1Rheumatology/Dept Int Med, University of Texas Medical Branch, Galveston, TX, 2Int Med/Rheumatology, University of Texas Medical Branch, Galveston, TX, 3Rheumatolgoy/Dept Int Med, University of Texas Medical Branch, Galveston, TX, 4Johns Hopkins University School of Medicine, Baltimore, MD, 5Div of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD

    Background/Purpose: Multiple cytokines play a role in the immune dysregulation seen in systemic lupus erythematosus (SLE) and the local inflammatory responses that ultimately lead to…
  • Abstract Number: 563 • 2012 ACR/ARHP Annual Meeting

    In Ankylosing Spondylitis, a Decrease in MRI Spinal Inflammation Predicts Improvement in Spinal Mobility Independently of Patient Reported Symptomatic Improvement

    Pedro Machado1, Robert Landewé2, Jürgen Braun3, Xenofon Baraliakos4, Kay-Geert A. Hermann5, Benjamin Hsu6, Daniel Baker7 and Désirée van der Heijde1, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam and Atrium Medical Center, Heerlen, Netherlands, 3PsAID taskforce, EULAR, Zurich, Switzerland, 4Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany, 5Radiology, Charité Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, 6Janssen Research & Development, LLC., Spring House, PA, 7Research and Development, Centocor Inc., Malvern/Philadelphia, PA

    Background/Purpose: It has been previously shown that spinal mobility in ankylosing spondylitis (AS) is associated with the level of inflammation of the spine. However an…
  • Abstract Number: 546 • 2012 ACR/ARHP Annual Meeting

    The Immunogenicity to the First Anti-TNF Therapy Determines the Outcome of Switching to a Second Anti-TNF in Spondyloarthritis Patients

    Chamaida Plasencia1, Dora Pascual-Salcedo2, Sara Garcia-Carazo3, Gema Bonilla4, Leticia Lojo5, Laura Nuño6, Alejandro Villalba7, Diana Peiteado7, Concepcion Castillo-Gallego7, Florencia Arribas2, Daniel Nagore8, E. Martin-Mola9 and Alejandro Balsa4, 1Rheumatology, Hospital La Paz-IdiPaz, Madrid, Spain, 2Immunology, Hospital La Paz. IdiPaz, Madrid, Spain, 3La PAZ University Hospital, RHEUMATOLOGY UNIT, Spain, Spain, 4Rheumatology, Hospital La Paz, Madrid, Spain, 5Rheumatology, Hospital Universitario La Paz, Spain, Spain, 6Hospital La Paz-IdiPaz, Madrid, Spain, 7Rheumatology, Hospital La Paz - IdiPaz, Madrid, Spain, 8Proteomika S.L., 9Servicio de Reumatología, Hospital Universitario La Paz, Madrid, Spain

    Background/Purpose: Spondyloarthropathies (SpAs) encompass a heterogeneous group of diseases that primarily affect the axial skeleton and entheses. Although anti-TNF drugs have proven to be effective…
  • Abstract Number: 421 • 2012 ACR/ARHP Annual Meeting

    Rheumatoid Factor, Not Antibodies to Citrullinated Proteins, Are Associated with High Disease Activity

    Josef S. Smolen1, Farideh Alasti2 and Daniel Aletaha3, 1Medical University of Vienna and Hietzing Hospital, Vienna, Austria, 2Department of Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 3Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria

    Background/Purpose: Autoantibodies in general, and rheumatoid factor (RF) and anti-citrullinated peptide antibodies (ACPA) in particular, are a hallmark of RA. After their characterization, ACPA have…
  • Abstract Number: 2609 • 2012 ACR/ARHP Annual Meeting

    Construct and Criterion Validity of Several Proposed DAS28 Based Rheumatoid Arthritis Flare Criteria: A Cohort Validation Study

    Aatke van der Maas1, Elisabeth Lie2, Robin Christensen3, Ernest Choy4, Yaël A. de Man5, Piet L.C.M. van Riel6, Thasia G. Woodworth7 and Alfons A. den Broeder1, 1Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, 2Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 3Department of Rheumatology, Musculoskeletal Statistics Unit, The Parker Institute, Copenhagen University Hospital, Copenhagen, Denmark, 4Section of Rheumatology, Cardiff University School of Medicine, Cardiff, United Kingdom, 5Rheumatology, Erasmus Medical Centre, Rotterdam, Netherlands, 6Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, 7Medicine, Division of Rheumatology, Visiting Clinical Researcher, Geffen School of Medicine, UCLA, Los Angeles, CA

    Background/Purpose: To enable consistent assessment of impact of tapering, withdrawal and dose optimization strategies, there is an increasing need for validated measures of flare in…
  • Abstract Number: 393 • 2012 ACR/ARHP Annual Meeting

    Defining Criteria for Rheumatoid Arthritis Patient-Derived Disease Activity Score That Corrresponds to Disease Activity Score 28 and Clnical Disease Activity Index Based Statuses and Response Criteria

    Alexander MH Leung1, Daniel Farewell2, Chak S. Lau3 and Ernest Choy4, 1Department of Rheumatology, Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, United Kingdom, 2Institute of Primary Care and Public Health, Cardiff, ENGLAND, United Kingdom, 3Univ Dept of Medicine, Queen Mary Hospital, Hong Kong, Hong Kong, 4Section of Rheumatology, Cardiff University School of Medicine, Cardiff, United Kingdom

    Background/Purpose: Patient-based disease activity score (PDAS1 [with ESR] & PDAS2 [without ESR]) in rheumatoid arthritis (RA) are validated patient reported outcome measures of disease activity.…
  • Abstract Number: 2618 • 2012 ACR/ARHP Annual Meeting

    Lupus Disease Activity Severely Impairs Pandemic Influenza A/H1N1 Vaccine Immune Response in Patients without Therapy

    Eduardo F. Borba1, Sandra G. Pasoto1, Ana L. Calich1, Ricardo Fuller1, Vilma S.T. Viana1, Margareth Vendramini1, Joao Miraglia2, Maria A. Ishida3 and Eloisa Bonfa4, 1Rheumatology Division, University of Sao Paulo, Sao Paulo, Brazil, 2Instituto Butantan, Fundação Butantan, São Paulo, Brazil, 3Instituto Adolfo Lutz, São Paulo, Brazil, 4Rheumatology Division, University of São Paulo, Sao Paulo, Brazil

    Background/Purpose: To determine the influence of disease activity without the effect of drugs in pandemic 2009 influenza A (H1N1) vaccine immune response in untreated systemic…
  • Abstract Number: 402 • 2012 ACR/ARHP Annual Meeting

    Discordant Inflammatory Markers in Veterans with Rheumatoid Arthritis: Baseline Characteristics and Relationship with Disease Activity

    Rebecca Belsom1, Archana Jain1, Jeffrey R. Curtis2, Shuo Yang3, Ted R. Mikuls4, Lang Chen5 and Angelo L. Gaffo6, 1Rheumatology, University of Alabama, Birmingham, AL, 2Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 3Clinical Immunology/Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 4Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, 5Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 6Medicine, Birmingham VA Medical Center and University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Discrepancies between erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) elevations with clinical disease activity frequently occur in rheumatoid arthritis (RA) patients and may…
  • Abstract Number: 2348 • 2012 ACR/ARHP Annual Meeting

    Plasma Fibrinogen Better Identifies Persistent Disease Activity in Polymyalgia Rheumatica Than Either ESR or CRP

    EM McCarthy1, Paul A. MacMullan1, S. Al-Mudhaffer1, Anne M. Madigan1, S. Donnelly1, C. J. McCarthy1, Dermot Kenny2, Eamonn Molloy3 and G M. McCarthy1, 1Rheumatology, Mater Misericordiae University Hospital, Dublin 7, Ireland, 2Molecular and Cellular Therapeutics, RCSI, Dublin 2, Ireland, 3Rheumatology, Dublin Academic Medical Centre, St. Vincent's University Hospital, Dublin, Ireland

    Background/Purpose: In PMR careful tailoring of the glucocorticoid dosage to the patients needs is crucial to avoid the risk of treatment-related adverse effects and the…
  • Abstract Number: 319 • 2012 ACR/ARHP Annual Meeting

    Gamma Interferon-Induced Protein-10 (IP-10) As a Potential Biomarker for Disease Activity in Pediatric Localized Scleroderma

    Katherine Kurzinski1, Carol A. Feghali-Bostwick2, Christina Kelsey1, Kelsey Magee3 and Kathryn S. Torok4, 1Pediatric Rheumatology, Univ of Pittsburgh Med Ctr, Pittsburgh, PA, 2Medicine, University of Pittsburgh, Pittsburgh, PA, 3Pediatric Rheumatology, University of Pittsburgh, Pittsburgh, PA, 4Pediatric Rheumatology, Scleroderma Center of Pittsburgh, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA

    Background/Purpose: Pediatric localized scleroderma (LS) is an autoimmune disease affecting the skin and underlying tissue.  Cutaneous findings assist in categorizing the patients into active or…
  • Abstract Number: 2121 • 2012 ACR/ARHP Annual Meeting

    A Multi-Biomarker Disease Activity (VECTRA™ DA Algorithm) Score Reflects Clinical Disease Activity and Structural Changes in Rheumatoid Arthritis Patients Treated with Tocilizumab

    Yoshiya Tanaka1, Kentaro Hanami2, Hisashi Tasaka1, Shunsuke Fukuyo1, Douglas J. Haney3, Nadine Defranoux3, Rebecca Bolce3, Guy Cavet3, David Chernoff3, Kunihiro Yamaoka1, Kazuyoshi Saito1 and Shintaro Hirata1, 1The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, 2The First Department of Internal Medicinei, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, 3Crescendo Bioscience Inc., South San Francisco, CA

    Background/Purpose: The multi-biomarker disease activity (MBDA) score assessed with 0.2 mL serum has been reported as a novel composite disease activity index for patients with…
  • Abstract Number: 277 • 2012 ACR/ARHP Annual Meeting

    Dyslipidemia in Juvenile Dermatomyositis: The Role of Disease Activity

    Katia T. Kozu1, Clovis Artur Silva2, Eloisa Bonfa3, Adriana M. Sallum4, Rosa M.R. Pereira5, Vilma S. Viana6, Eduardo F. Borba7 and Lucia M. A. Campos4, 1Pediatric Rheumatology Unit, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 2Paediatric Rheumatology International Trials Organization (PRINTO), Istituto Giannina Gaslini, Genova, Italy, 3Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 4Pediatric Rheumatology Unit, Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, 5Rheumatology, University of São Paulo, São Paulo, Brazil, 6Rheumatology Division, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, 7Rheumatology Division, University of Sao Paulo, Sao Paulo, Brazil

    Background/Purpose: Dyslipidemia has been infrequently investigated in pediatric population with autoimmune rheumatic diseases. However, lipid abnormalities in these diseases may occur due to multiple risk…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

ACR Abstract Embargo Policy

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying financial and other sponsors about this policy. If you have questions about the abstract embargo policy, please contact the public relations department at [email protected].

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