Session » (0934–0964) Systemic Sclerosis & Related Disorders – Basic Science Poster
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Abstract Number: 0935
Sodium Pyruvate Improves Mitochondrial Fitness in SSc Fibroblasts to Prevent Fibroblast-to-myofibroblast Transition and Fibrotic Remodeling
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Abstract Number: 0936
Impaired DNA Repair Responses Activate a Novel FOXO1-dependent Metabolic Remodelling in Patients with Progressive Systemic Sclerosis to Promote Fibrosis
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Abstract Number: 0937
IL-4+ and IFN-α+ Profibrotic T Cells Aggravate Systemic Sclerosis via STIM1/STING Signaling in SKG Mice
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Abstract Number: 0938
Deconvolution of the Molecular Signature of Very Early Diagnosis of Systemic Sclerosis (VEDOSS) and Established Disease: A Biomarker Blueprint of Scleroderma Disease Continuum
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Abstract Number: 0939
HRCT-derived Delta Radiomic Features Classify Response to Anti-Fibrotic Treatment in Experimental and Human Fibrosing Interstitial Lung Disease
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Abstract Number: 0940
A Novel Therapeutic Opportunity in Systemic Sclerosis: The Fibrolytic Activities of a Specialized Macrophage Secretome
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Abstract Number: 0941
RUNX1 Expression and Binding Site Accessibility Is Associated with Increased Disease Severity in Systemic Sclerosis
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Abstract Number: 0942
G Protein-coupled Receptor Kinase 5 in Fibrotic Tissue Remodeling
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Abstract Number: 0943
Attenuation of Fibroblast Activation and Fibrosis by Adropin in a Hedgehog-Dependent Manner
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Abstract Number: 0944
Macrophages Regulate Adipocyte Differentiation and Proliferation in Skin Fibrosis
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Abstract Number: 0945
The Nuclear Receptor TR4 Orchestrates Cytoskeletal Organization in a Gα12/ROCK-dependent Manner to Promote Myofibroblast Differentiation and Tissue Fibrosis in Systemic Sclerosis
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Abstract Number: 0946
Immunoglobulins G Purified from Systemic Sclerosis Patients Influence Cytoplasmic and Nuclear Proteins Profile in Dermal Fibroblasts
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Abstract Number: 0947
Fcγ Receptors Define Pro-Phagocytic Macrophages and Trigger Pro-Inflammatory Responses in Patients with Systemic Sclerosis
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Abstract Number: 0948
Nintedanib Alters Fibroblast and Macrophage Diversity in a 3D Skin Model of Systemic Sclerosis (SSc)
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Abstract Number: 0949
Development of Interstitial Pneumonia with Autoimmune Features in Conditional Tgfb3 Deletion
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Abstract Number: 0950
KL-6 and IL-18 Levels Are Negatively Correlated with Respiratory Function Tests and ILD Extent Assessed on HRCT in Patients with Systemic Sclerosis-related Interstitial Lung Disease (SSc-ILD)
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Abstract Number: 0951
Single Cell Analysis of Transitional B Cells in Systemic Sclerosis Highlights Defective Peripheral Tolerance
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Abstract Number: 0952
Unraveling the Role of MiR-181 in Skin Fibrosis Pathogenesis by Targeting NUDT21
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Abstract Number: 0953
Flavin-containing Monooxygenase (FMO3) Links the Gut and Fibrosis in Systemic Sclerosis
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Abstract Number: 0954
Non-canonical WNTA Promotes Cytoskeletal Rearrangement and Integrin Alpha V Clustering via JNK and ROCK to Control the Activation of Latent TGFβ
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Abstract Number: 0955
GRB2 Serves as a Viable Target Against Skin Fibrosis in Systemic Sclerosis by Regulating Endothelial Cell Apoptosis
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Abstract Number: 0956
Effects of B Cell Depletion by CD19-targeted CAR-T Cells in a Murine Model of Systemic Sclerosis
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Abstract Number: 0957
Rationale for Targeting Insulin-like Growth Factor Signalling in Systemic Sclerosis
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Abstract Number: 0958
Shared Genetic Susceptibility Between Systemic Sclerosis and Primary Biliary Cholangitis: Analyses from Genome-Wide Association Studies
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Abstract Number: 0959
Redirecting Macrophage Immunophenotype Attenuates Inflammation and Fibrotic Activation in Systemic Sclerosis
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Abstract Number: 0960
MiR-3606-3p Alleviates Skin Fibrosis by Suppressing Fibroblast Inflammation and Migration via Inhibiting GAB1 and ITGAV
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Abstract Number: 0961
Transcriptomic Analysis of Scleroderma Monocytes Identifies Distinct Clinically Relevant Clusters and Novel Genes Associated with Disease Complications
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Abstract Number: 0962
Topological Proteomic Differences in Fibrotic and Unaffected Skin in Scleroderma