Session » (0897–0915) B Cell Biology & Targets in Autoimmune & Inflammatory Disease Poster II

Date: Monday, October 27, 2025

Time: 10:30AM-12:30PM

Meeting: ACR Convergence 2025

10:30AM-12:30PM: Abstract Number: 0915

A fusion of TACI variant and anti-IFNAR antibody with greater therapeutic effect on related autoimmune disease models

10:30AM-12:30PM: Abstract Number: 0902

A Novel Approach to study ANA+ B Cells in Lupus Integrating Flow Cytometry with Single-Cell culture

10:30AM-12:30PM: Abstract Number: 0911

A Novel FcRn × Albumin Bispecific Antibody Demonstrates Extended Half-life and Deep IgG Reduction in Preclinical Mouse Models

10:30AM-12:30PM: Abstract Number: 0899

Altered B cell Subsets Shared in Immune Checkpoint Inhibitor Associated Sicca Syndrome and Sjogren’s Disease

10:30AM-12:30PM: Abstract Number: 0897

APECED Disease Reorganizes The B Cell Compartment Toward Alternatively Activated Subsets

10:30AM-12:30PM: Abstract Number: 0912

CD11c⁺CD21⁻ Autoimmune-Associated B Cells Derived from Double-Negative IgD⁻CD27⁻ Subsets Exhibit Enhanced IFNLR1 Expression in Systemic Lupus Erythematosus

10:30AM-12:30PM: Abstract Number: 0907

Cross-Species Cellular Mapping and Humanization of Fcγ Receptors to Advance Antibody Modeling

10:30AM-12:30PM: Abstract Number: 0901

Data-Driven Metabolomics Identifies Diagnostic Signatures and Patient Subgroups in Systemic Autoimmune Disorders

10:30AM-12:30PM: Abstract Number: 0905

Development and Characterization of IAR130, a 2+1 Format, CD19 and BCMA Dual Targeting T Cell Engager for Autoimmune Diseases

10:30AM-12:30PM: Abstract Number: 0910

Development of Four Distinct Human IgG4-Producing Mouse Models Recapitulating IgG4-Related Disease

10:30AM-12:30PM: Abstract Number: 0898

Distinct B Cell and Plasma Cell Immunosuppression Strategies Eliminate Antigen-Specific Cells of the B Lineage

10:30AM-12:30PM: Abstract Number: 0908

E-602 (Efgitasialase alfa) Enhances Memory B Cell Depletion and Reduces Profibrotic Macrophages via Desialylation in Autoimmune Disease

10:30AM-12:30PM: Abstract Number: 0903

Ianalumab‘s dual mode of action: targeting B cells through enhanced B cell depletion and blockade of B cell-activating factor receptor signaling

10:30AM-12:30PM: Abstract Number: 0909

Loss of MicroRNA29 expression in B cells and skin microbiota synergize to promote atopic dermatitis in mice.

10:30AM-12:30PM: Abstract Number: 0913

Potent and Selective Oral IRF5 Degrader, KT-579, Demonstrates In Vitro and In Vivo Activity Comparable or Superior to Approved or Clinically Active Agents in Human Cellular Assays and Lupus Efficacy Models

10:30AM-12:30PM: Abstract Number: 0906

Preclinical Characterization of IBI3034, an TACI and BCMA Chimeric Fc Fusion Protein, that Potently Modulates B Lymphocytes and Serum Immunoglobulin for the Treatment of B cell Related Autoimmune Disease

10:30AM-12:30PM: Abstract Number: 0914

Preclinical Expansion of Autoreactive Naive B cells Drives RA onset in ACPA+ individuals

10:30AM-12:30PM: Abstract Number: 0900

Profiling of Novel Autoantibodies for Prediction of Disease Activity in ANCA-Associated Vasculitis

10:30AM-12:30PM: Abstract Number: 0904

SLAMF7 Drives Plasma Cell Differentiation in Rheumatoid Arthritis Synovium.

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