Abstract Number: 192 • 2016 ACR/ARHP Annual Meeting
Pharmacodynamic and Pharmacokinetic Study of Verinurad in Adult Male Subjects with Mild, Moderate, and Severe Renal Impairment: A Phase 1, Open-Label Study
Background/Purpose: Verinurad (RDEA3170) is a high-affinity, selective URAT1 inhibitor in development for the treatment of gout and asymptomatic hyperuricemia. This Phase 1, single-dose, open-label study…Abstract Number: 193 • 2016 ACR/ARHP Annual Meeting
Pharmacokinetics, Pharmacodynamics, and Tolerability of Verinurad, a Selective Uric Acid Reabsorption Inhibitor, in Healthy Japanese Male Subjects
Background/Purpose: This was a Phase 1, randomized, single-blind, placebo-controlled study (. Panels of 8 Japanese male subjects were randomized in a 3:1 ratio to receive…Abstract Number: 205 • 2016 ACR/ARHP Annual Meeting
Serum Uric Acid Lowering Treatment Appears Unnecessary during Hemodialysis
Background/Purpose: Gout patients often suffer from renal disease, some ultimately developing end-stage renal disease (ESRD) and requiring hemodialysis (HD) replacement therapy. Though some reports suggested…Abstract Number: 206 • 2016 ACR/ARHP Annual Meeting
Renal Safety of Lesinurad: A Pooled Analysis of Phase III and Extension Studies
Background/Purpose: Lesinurad is a selective uric acid reabsorption inhibitor approved in the United States and European Union at 200 mg daily dose in combination with…Abstract Number: 211 • 2016 ACR/ARHP Annual Meeting
Safety and Efficacy of Febuxostat in Advanced CKD Patients with Hyperuricemia
Background/Purpose: Dosing adjustments and increased risk of serious side effects of uric acid lowering agents in patients with reduced renal function lead to undercorrection of…Abstract Number: 213 • 2016 ACR/ARHP Annual Meeting
Prophylaxis for Infusion Reactions to Pegloticase: An Analyis of Two Different Corticosteroid Pre-Infusion Regimens in US Community Rheumatology Practices
Background/Purpose: Corticosteroids are commonly utilized, along with other agents in clinical practice for pre-infusion prophylaxis prior to the administration of therapeutic biologic proteins. Two steroids,…Abstract Number: 214 • 2016 ACR/ARHP Annual Meeting
Anakinra Compared to Prednisone on the Treatment of Acute CPPD Crystal Arthritis, a Randomized, Controlled, Double-Blind Study
Background/Purpose: Calcium pyrophosphate crystal-induced arthritis (CPPD) is an acute crystal arthritis, frequently involving the wrist or the knee. Monosodium urate in gout or CPPD…Abstract Number: 218 • 2016 ACR/ARHP Annual Meeting
Accuracy of Humasens-Plus Point-of-Care Uric Acid Meter Using Capillary Blood Obtained By Fingertip Puncture
Background/Purpose: A key factor in the success of gout management is the long-term lowering of serum uric acid (sUA) levels below predetermined targets (5 or…Abstract Number: 222 • 2016 ACR/ARHP Annual Meeting
Role of Synovial Biopsy in Diagnosis of Crystal Arthropathies
Title: Role of Synovial Biopsy in Diagnosis of Crystal Arthropathies Background/Purpose: Diagnosis of crystal arthropathies (CAs) can be challenging. Advances in arthroscopy and ultrasound guided…Abstract Number: 649 • 2016 ACR/ARHP Annual Meeting
Clinical Evaluation Usefulness of Standardized Protocol Strategies of Dose Reduction in Patients with Rheumatoid Arthritis in Clinical Remission Treated with Biologic Therapies. the Optibio Study
Background/Purpose: The OPTIBIO study is a clinical trial whose primary endpoint is to evaluate the proportion of patients that after one year are maintained in…Abstract Number: 1099 • 2016 ACR/ARHP Annual Meeting
Synovial Exosomes Induce Osteoclast Differentiation in Rheumatoid arthritis
Background/Purpose: Exosomes are small membrane vesicles (40-150 nm) of endocytic origin secreted by many types of cells and engage in cell-to-cell communication by transferring proteins,…Abstract Number: 1135 • 2016 ACR/ARHP Annual Meeting
Long-Term Impact of an Enhanced Rheumatology Curriculum for Internal Medicine Residents
Background/Purpose: Internal medicine (IM) residents need to be trained in the diagnosis and care of patients with rheumatologic disease. Our prior data show that a…Abstract Number: 1138 • 2016 ACR/ARHP Annual Meeting
Rheumapalooza Update: Applying a Flipped Classroom Instructional Model to an Intensive Rheumatology Curriculum for Second Year Medical Students
Background/Purpose: Rheumapalooza was implemented in 2008 as a 2 half-day elective course with support from an ACR/REF Clinical Scholar Educator Award. Course evaluation demonstrated significant…Abstract Number: 1170 • 2016 ACR/ARHP Annual Meeting
Month of Birth Affects the Risk of Rheumatic Diseases: A Nationwide Case-Control Study
Background/Purpose: There have been several studies which demonstrated the impact of birth on the risk of certain diseases such as asthma or cardiovascular diseases. However,…Abstract Number: 1260 • 2016 ACR/ARHP Annual Meeting
Association of Traditional Chinese Medicine Use and Adherence to Prescribed Western Medications in Chinese-American Rheumatology Patients
Background/Purpose: Chinese-Americans are one of the fastest growing immigrant groups in the US. They often use Traditional Chinese Medicine (TCM), but whether that affects medication…
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