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  • Abstract Number: 2056 • 2017 ACR/ARHP Annual Meeting

    Performance and Validity of Musculoskeletal Ultrasound in the Assessment of Synovial Inflammation in Experimental Acute Gout

    Raquel Largo1, Juan Pablo Medina2, Sandra Perez-Baos2, Victor Najera-Aleson2, Aranzazu Mediero2, Gabriel Herrero-Beaumont1 and Esperanza Naredo3, 1Bone and Joint Research Unit, IIS-Fundacion Jimenez Diaz UAM, Madrid, Spain, 2Joint and Bone Research Unit, IIS-Fundacion Jimenez Diaz UAM, Madrid, Spain, 3Rheumatology, Joint and Bone Research Unit, IIS-FJD, Hospital Universitario Fundación Jiménez Díaz., Madrid, Spain

    Background/Purpose: Musculoskeletal ultrasound (MS-US) has not been validated as a reliable technique to evaluate joint inflammation in an acute gout rabbit model. Rabbit has been…
  • Abstract Number: 2058 • 2017 ACR/ARHP Annual Meeting

    A Study on Febuxostat Prescribing Practices for Patients with Chronic Gout Previously Managed with Allopurinol at the Veterans Affairs Puget Sound

    Percy Balderia and Elizabeth R. Wahl, Rheumatology, University of Washington School of Medicine, Seattle, WA

    Background/Purpose: American College of Rheumatology (ACR) guidelines recommend use of either allopurinol or febuxostat as first-line approaches to urate lowering therapy in gout. Prior studies…
  • Abstract Number: 2059 • 2017 ACR/ARHP Annual Meeting

    Allopurinol Dose-Titration Patterns Relative to Serum Uric Acid Levels in Gout Patients: US Electronic Health Record Data

    An-Chen Fu, Douglas C.A. Taylor and David S. Reasner, Ironwood Pharmaceuticals, Inc., Cambridge, MA

    Background/Purpose: Gout is the most common form of inflammatory arthritis and is caused by elevated serum uric acid (sUA). Allopurinol is a first-line urate-lowering therapy…
  • Abstract Number: 2060 • 2017 ACR/ARHP Annual Meeting

    Pseudogout Among Patients Fulfilling a Billing Code Algorithm for Calcium Pyrophosphate Deposition Disease (CPPD)

    Sara K. Tedeschi, Daniel H. Solomon and Katherine P. Liao, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Calcium pyrophosphate deposition disease (CPPD) has a spectrum of manifestations, of which pseudogout is the most acute inflammatory phenotype. Studies focusing on pseudogout are…
  • Abstract Number: 2062 • 2017 ACR/ARHP Annual Meeting

    Flow-Mediated Dilation As a Marker of Endothelial Dysfunction in Gout

    Enrique Calvo Aranda1, Ofelia Carrion2, Afnan Abdelkader2, Jorge Juan González Martín3, Francisco Aramburu3, Marta Valero4, Silvia Rodriguez4, Carolina Marin3, Irene Amil3, Felipe Sainz5 and Paloma Garcia De La Peña3, 1RHEUMATOLOGY, Hospital Madrid Norte Sanchinarro, Madrid, Spain, 2Vascular Surgery Department, Hospital Madrid Norte Sanchinarro, Madrid, Spain, 3Rheumatology, Hospital Madrid Norte Sanchinarro, Madrid, Spain, 4Rheumatology, Hospital Madrid Norte Sanchinarro, MADRID, Spain, 5Vascular Surgery, Hospital Madrid Norte Sanchinarro, MADRID, Spain

    Background/Purpose: Several studies have shown the relationship between gout and increased cardiovascular risk and mortality. Hyperuricemia and crystal-induced synovitis are associated with endothelial dysfunction and…
  • Abstract Number: 2063 • 2017 ACR/ARHP Annual Meeting

    Relation of Serum Urate and Gout Duration to Tophi, Urate Deposition, and Inflammation

    Ana Beatriz Vargas-Santos1, S. Reza Jafarzadeh2, Geraldo Castelar-Pinheiro1, Nicola Dalbeth3, William J. Taylor4, Jaap Fransen5, Tim L. Jansen6, H. Ralph Schumacher7 and Tuhina Neogi2, 1Internal Medicine - Rheumatology, State University of Rio de Janeiro, Rio de Janeiro, Brazil, 2Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 3University of Auckland, Auckland, New Zealand, 4Department of Medicine, University of Otago, Wellington, New Zealand, 5Department of Rheumatolgy, Radboud University Medical Center, Nijmegen, Netherlands, 6Rheumatology, Radboud University Medical Center, Nijmegen, Netherlands, 7Medicine, Rheumatology, U Penn & VA Med Ctr, Philadelphia, PA

    Background/Purpose: Gout duration and serum urate (SU) levels are thought to influence development of tophi and chronic inflammatory gouty arthropathy, but the extent to which…
  • Abstract Number: 2064 • 2017 ACR/ARHP Annual Meeting

    The Nomenclature of Gout: A Content Analysis of Contemporary Medical Journals

    David Bursill1,2, William J. Taylor3, Robert Terkeltaub4 and Nicola Dalbeth5, 1Medicine, University of Auckland, Auckland, New Zealand, 2School of Medicine, University of Adelaide, Adelaide, Australia, 3University of Otago, Wellington, New Zealand, 4Rheumatology, VA San Diego Healthcare System, San Diego, CA, 5University of Auckland, Auckland, New Zealand

    Background/Purpose: Gout has been recognized and described since antiquity. However, the terms used to describe the disease lack standardization. The aim of this study was…
  • Abstract Number: 2065 • 2017 ACR/ARHP Annual Meeting

    Higher Urate Volume Measured By Dual Energy Computed Tomography Is Associated with Unfavourable Cardiovascular Risks in Patients with Gout

    Sang Heon Lee1, Hae-Rim Kim2, Kyung-Ann Lee3 and Jin Wuk Hur4, 1Division of Rheumatology, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea, Republic of (South), 2Division of Rheumatology, Department of Internal Medicine, Konkuk University Medical Center, Seoul, Korea, Republic of (South), 3Department of Nuclear medicine, Konkuk University Medical center, seoul, Korea, Republic of (South), 4Rheumatology, Eulji University College of Medcine, Seoul, Korea, Republic of (South)

    Background/Purpose: Hyperuricemia and gout are associated with increased risk of cardiovascular disease. The aim of the study was to evaluate the correlation between cardiovascular risk…
  • Abstract Number: 2066 • 2017 ACR/ARHP Annual Meeting

    Mediation Analysis to Understand Genetic Relationships between Habitual Coffee Intake and Gout

    Joseph Hutton1, Tanya Major2, Ruth Topless3, Tony R. Merriman4 and Nicola Dalbeth1, 1University of Auckland, Auckland, New Zealand, 2Biochemistry, University of Otago, Dunedin, New Zealand, 3University of Otago, Dunedin, New Zealand, 4Biochemistry Dept, PO Box 56, University of Otago, Dunedin, New Zealand

    Background/Purpose: Increased coffee intake is associated with reduced serum urate concentrations and lower risk of gout. Recent genome wide association studies (GWAS) have shown that…
  • Abstract Number: 2067 • 2017 ACR/ARHP Annual Meeting

    Treatment with Pegloticase Significantly Decreases Mean Arterial Blood Pressure in Patients with Chronic Gout

    Hyon K. Choi1, Richard Johnson2, Anthony Yeo3 and Peter E. Lipsky4, 1Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 2Medicine, University of Colorado Denver, Aurora, CO, 3Horizon Pharma, Lake Forest, IL, 4AMPEL BioSolutions, LLC, Charlottesville, VA

    Background/Purpose:   There are significant correlations between serum uric acid (sUA) and blood pressure (BP) in individuals with and without gout.1 Limited data suggest that lowering…
  • Abstract Number: 2068 • 2017 ACR/ARHP Annual Meeting

    Previous Prescription of Allopurinol Reduces the Risk of Nsaids-Related Acute Kidney Injury in Patients with Gout

    Fernando Perez-Ruiz1 and Sandra Chinchilla2, 1BioCruces Health Research Institute, Barakaldo, Spain, 2Rheumatology Division, Hospital Universitario Cruces, Baracaldo, Spain

    Background/Purpose: untreated or undertreated gout is characterized by recurrent episodes of acute inflammation of joint structures, called gout flares, and flares are commonly treated with…
  • Abstract Number: 2069 • 2017 ACR/ARHP Annual Meeting

    Gout Is More Frequent in Sickle Cell Disease Than the General Population

    Richard Akintayo1, Olufemi Adelowo2, Adindu Chijioke1, Timothy Olanrewaju1, Kehinde Olufemi-Aworinde3 and Foluke Akintayo4, 1Internal Medicine, University of Ilorin Teaching Hospital, Ilorin, Nigeria, 2Arthrimed Specialist Clinic:The Arthritis Centre, Lagos, Nigeria, 3Haematology, Bowen University Teaching Hospital, Ogbomosho, Nigeria, 4Family Medicine, Ladoke Akintola University of Technology Teaching Hospital, Ogbomosho, Nigeria

    Background/Purpose: Despite the well known risk of hyperuricaemia in Sickle Cell Disease (SCD), it has not been determined if these patients are more prone to…
  • Abstract Number: 2070 • 2017 ACR/ARHP Annual Meeting

    Evidence-Based Development of Criteria for Complete Response in Patients with Chronic Refractory Gout

    Naomi Schlesinger1, Puja Khanna2, Anthony Yeo3 and Peter E. Lipsky4, 1Medicine, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, 2Rheumatology, University of Michigan, Ann Arbor, MI, 3Horizon Pharma, Lake Forest, IL, 4AMPEL BioSolutions, LLC, Charlottesville, VA

    Background/Purpose: A Delphi exercise reached consensus on a definition for gout remission that included serum uric acid (sUA) <6 mg/dL, no flares, resolution of all…
  • Abstract Number: 2073 • 2017 ACR/ARHP Annual Meeting

    Predictors for Clinically Diagnosed Gout – Results from 30 Years Follow-up of the Malmö Preventive Project Cohort in Southern Sweden

    Meliha C. Kapetanovic1, Peter M Nilsson2, Carl Turesson3, Nicola Dalbeth4, Martin Englund5, Lieke E.J.M. Scheepers6 and Lennart TH Jacobsson6, 1Lund University, Skane University Hospital, Department of Rheumatology, Lund, Sweden, Lund, Sweden, 2Department of Clinical Sciences, Lund University, Skåne University Hospital Malmö, Sweden., Lund, Sweden, 3Department of Rheumatology, Skåne University Hospital, Malmö, Sweden, 4University of Auckland, Auckland, New Zealand, 5Clinical Sciences Lund, Orthopedics, Clinical Epidemiology Unit, Lund University, Lund, Sweden, 6Department of Rheumatology and Inflammation Research, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

    Background/Purpose: Gout is the most common form of arthritis worldwide. Hyperuricemia is a crucial risk factor resulting in accumulation of uric acid (s-UA) crystals in…
  • Abstract Number: 2074 • 2017 ACR/ARHP Annual Meeting

    A Series of Double-Blind, Placebo-Controlled, Randomized, Multicenter, Phase 2 Studies to Evaluate the Efficacy, Safety, and Dose-Response Relationship of Orally Administered URC102, a Novel URAT1 Inhibitor, in Korean Patients with Gout

    Jae-Bum Jun1, Howard Lee2, Chang-Hee Suh3, Chang Keun Lee4, Dong Wook Kim5, Jung-Yoon Choe6, Sang-Heon Lee7, Sang-Hyon Kim8, Seung-Jae Hong9, So-Young Bang10, Sung Jae Choi11, Yong-Beom Park12, Makoto Onohara13, Jeongeun Choi14, Jung Soo Song15 and Won Park16, 1Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea, Republic of (South), 2Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea, Republic of (South), 3Ajou University School of Medicine, Suwon, Korea, Republic of (South), 4Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea, Republic of (South), 5Division of Rheumatology, Department of Internal Medicine, Inje University College of Medicine, Busan, Korea, Republic of (South), 6Division of Rheumatology, Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea, Republic of (South), 7Division of Rheumatology, Department of Internal Medicine,, Konkuk University School of Medicine, Seoul, Korea, Republic of (South), 8Division of Rheumatology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Republic of Korea, Daegu, Korea, Republic of (South), 9Department of Rheumatology, Kyung Hee University Medical Center, Seoul, Korea, Republic of (South), 10Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea, Republic of (South), 11Internal Medicine, Korea University Medical Center, Seoul, Korea, Republic of (South), 12Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea, Republic of (South), 13Science and Strategy, Translational Clinical Research, Chugai Pharmaceutical Co., Ltd, Tokyo, Japan, 14JW Pharmaceutical Corporation, Seoul, Korea, Republic of (South), 15Rheumatology, Chung-Ang University College of Medicine, Seoul, Korea, Republic of (South), 16Medicine/Rheumatology, Inha University Hospital, Incheon, Korea, Republic of (South)

    Background/Purpose: URC102 is a novel URAT1 inhibitor under clinical development for the treatment of hyperuricemia with gout. A series of double-blind, placebo-controlled, randomized, multicenter, phase…
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Embargo Policy

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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