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  • Abstract Number: 1134 • 2017 ACR/ARHP Annual Meeting

    A Case Series of Gout and Downs Syndrome – a New Paradigm for Detecting Disease Associations Using Big Data

    Ann Igoe1,2,3, Bryan A Roller4,5, Abbinaya Elangovan5,6, Kristin L Kaelber4,6 and David Kaelber4,5,6,7, 1Internal Medicine & Pediatrics, Metrohealth Medical Center, Cleveland, OH, 2Rheumatology, Metrohealth Medical Center, Cleveland, OH, 3Metrohealth Medical Center, Metrohealth Medical Center, Cleveland, OH, 4School of Medicine, Case Western Reserve, Cleveland, OH, 5Center for Clinical Informatics Research and Education, Metrohealth Medical Center, Cleveland, OH, 6Dept of Internal Medicine & Pediatrics, Metrohealth Medical Center, Cleveland, OH, 7Departments of Information Services, Metrohealth Medical Center, Cleveland, OH

    Background/Purpose: Down syndrome (Trisomy 21) is known to have higher prevalence of certain conditions including cardiac defects, hypothyroidism, hearing defects and early Alzheimer’s disease, but…
  • Abstract Number: 1136 • 2017 ACR/ARHP Annual Meeting

    Urate-Lowering Treatment and Risk of Total Joint Replacement in Patients with Incident Gout: A Population-Based Cohort and Nested Case-Control Study

    Jung-Sheng Chen, Chang-Fu Kuo, Ping-Han Tsai, Shue-Fen Luo and Kuang-Hui Yu, Division of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Taoyuan, Taiwan

    Background/Purpose: This cohort study aimed to investigate the risk of total joint (hip/knee) replacement (TJR, THR and TKR) among patients with incident gout at initial…
  • Abstract Number: 1137 • 2017 ACR/ARHP Annual Meeting

    Urate Lowering to ACR-Recommended Targets Allows Significant Improvement of Severe Gout: A Monocentric Prospective Trial in Vietnam, Using a Systematic Treatment Protocol

    Thomas Bardin1,2,3, Quang Nguyen Dinh1, Khoi Tran Minh1, Nghia Le Hieu1, Minh Do Duc4, Pascal Richette5,6 and Matthieu Resche-Rigon3,7, 1French-Vietnamese Gout Research Center, Ho Chi Minh City, Viet Nam, 2Rheumatology, Hôpital Lariboisière, Paris, France, 3Université Paris Diderot, Paris, France, 4Molecular Biology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Viet Nam, 5Rhumatologie, Hôpital Lariboisière, Paris, France, 6Rheumatology Department, Université Paris Diderot, Paris, France, 7Biostatistics, Hôpital Saint-Louis, Paris, France

    Background/Purpose: Gout is frequent and severe in Vietnam, where urate-lowering drugs (ULD) are seldom used and many patients are treated only with traditional herbal medicine.…
  • Abstract Number: 1138 • 2017 ACR/ARHP Annual Meeting

    Investigation on Allele Frequency of Rs3117583 and Rs9263726 in Patients with Hyperuricemia or Gout

    Xiaomin Li1, Qiujing Wei2, Naomi Schlesinger3 and Jieruo Gu2, 1Rheumatology, Third affiliated hospital of Sun Yat-sen University, Guangzhou, China, 2Rheumatology, Third affiliated hospital of Sun Yat-sen Universtiy, Guangzhou, China, 3Medicine, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ

    Background/Purpose: Allopurinol, effectively regulates and controls serum uric acid levels but may cause allopurinol-induced life-threating severe cutaneous adverse reaction (SCAR). Previous studies reported that single…
  • Abstract Number: 1139 • 2017 ACR/ARHP Annual Meeting

    Management of Gout – a Survey for Healthcare Providers in South Australia

    Nieves Leonardo1 and Julian McNeil2, 1Rheumatology, The Queen Elizabeth Hospital, Woodville South, Australia, 2Rheumatology, Northern Adelaide Local Health Network, Modbury, Australia

    Background/Purpose: Gout is a treatable arthritis and while the rate of gout in Australia has been steadily rising, drugs used to treat acute gouty arthritis…
  • Abstract Number: 1140 • 2017 ACR/ARHP Annual Meeting

    Gout Characteristics and Its Association with the Presence of Cardiovascular Disease: A Case-Control Study

    Mariano Andrés1,2, Salvador López-Salguero1, Francisca Sivera3, Loreto Carmona4, Paloma Vela1,2 and Eliseo Pascual1,5, 1Sección de Reumatología, Hospital General Universitario de Alicante, Alicante, Spain, 2Departamento de Medicina Clínica, Universidad Miguel Hernández, Alicante, Spain, 3Sección de Reumatología, Hospital General Universitario de Elda., Elda, Spain, 4Instituto de Salud Musculoesquelética (InMusc), Madrid, Spain, 5Emeritus Professor, Universidad Miguel Hernández, Elche, Spain

    Background/Purpose: Gout is an independent risk factor for any type of cardiovascular disease (CVD). The exact mechanism behind remains to be elucidated, but persistent crystal-related…
  • Abstract Number: 1142 • 2017 ACR/ARHP Annual Meeting

    A Case Control Study of Anakinra Use for Acute Gout in a VA Patient Cohort Reveals Association with East Asian Descent, High Urate Burden, and Increased Co-Morbidities and All-Cause Mortality

    Ena Sharma1 and Robert Terkeltaub2, 1Rheumatology, University Of California San Diego, San Diego, CA, 2Rheumatology, VA San Diego Healthcare System, San Diego, CA

    Background/Purpose: Effectiveness of the IL-1 receptor antagonist anakinra, in resolving flares of acute gout, has been reported in several case series. Here, studying a VA…
  • Abstract Number: 1143 • 2017 ACR/ARHP Annual Meeting

    The Patient Education for Gout Patients Ameliorate the Patients’ Satisfaction and Serum Uric Acid Level

    In-Seol Yoo1, Chan Keol Park2, Jinhyun Kim1, Su-Jin Yoo3, Seung-Cheol Shim1 and Seong Wook Kang2, 1Division of Rheumatology, Department of Internal Medicine, Daejeon Rheumatoid & Degenerative Arthritis Center, Chungnam National University Hospital, Daejeon, Korea, Republic of (South), 2Internal medicine, Daejeon Rheumatoid & Degenerative Arthritis Center, Chungnam National University Hospital, Daejeon, Korea, Republic of (South), 3Rheumatology, Daejeon Rheumatoid & Degenerative Arthritis Center, Chungnam National University Hospital, Daejeon, Korea, Republic of (South)

    Background/Purpose: The poor adherence to urate lowering therapy is due to a lack of appropriate information. This study performed to analyze the effect of education…
  • Abstract Number: 1144 • 2017 ACR/ARHP Annual Meeting

    Initiating Colchicine and Urate-Lowering Therapy Reduces Baseline Inflammation, and Improves Vascular Endothelial but Not Smooth Muscle Function in Gout Subjects: Resistance to Endothelial Improvement Among Patients with Cardiovascular Comorbidities

    Talia Igel1,2, Aaron Garza Romero2, Virginia Pike3, Yu Guo4, Stuart Katz5, Binita Shah5, Irina Dektiarev5, Svetlana Krasnokutsky Samuels2 and Michael Pillinger2, 1Medicine, Monash University School of Medicine, Melbourne, Australia, 2Medicine/Rheumatology, New York University School of Medicine, New York, NY, 3Medicine/Rheumatology, New York University School of Medicine, Division of Rheumatology, New York, NY, 4Population Health/Statistics, New York University School of Medicine, New York, NY, 5Medicine/Cardiology, New York University School of Medicine, New York, NY

    Background/Purpose: We have previously reported that patients with gout have impaired vascular endothelial and smooth muscle responsiveness, but whether initiating appropriate gout therapy ameliorates these…
  • Abstract Number: 1145 • 2017 ACR/ARHP Annual Meeting

    Effectiveness of a Multidisciplinary Gout Clinic on Timely Achievement of Serum Uric Acid Goals

    Kah Mun Cheong1, Archana Vasudevan2, Melonie Sriranganathan2, Elena Lee1, Serene Yeow1 and Prista Ramskay1, 1Department of Pharmacy, Changi General Hospital, Singapore, Singapore, Singapore, 2Department of Medicine, Changi General Hospital, Singapore, Singapore, Singapore

    Background/Purpose: The concept of a multidisciplinary gout clinic is relatively new in Singapore. Changi General Hospital launched such a clinic in 2014 to provide treat-to-target…
  • Abstract Number: 1146 • 2017 ACR/ARHP Annual Meeting

    Associations between Gout and Cancer in an Nhanes Cohort

    Patricia Kachur1, Venkatesh Gondhi2, Yinjin Wert3 and Pramil Cheriyath2, 1Internal Medicine, Ocala Regional Medical Center, Ocala, FL, 2Ocala Regional Medical Center, Ocala, FL, 3Pinnacle Health System, Harrisburg, PA

    Background/Purpose: Gout is the most common inflammatory disease in the United States (US), affecting more than 4% of the population. Although uric acid (UA) can…
  • Abstract Number: 1864 • 2017 ACR/ARHP Annual Meeting

    Longitudinal Changes in Serum Uric Acid Levels and Associated Risk of Cardiometabolic Events and Renal Insufficiency in Gout Patients

    Rishi J. Desai1, Jessica Franklin2, Julia Spoendlin2, Goodarz Danaei3, Daniel H. Solomon4 and Seoyoung C. Kim5, 1PharmacoEpidemiology & PharmacoEconomics, Brigham & Women's Hospital, Boston, MA, 2Brigham & Women's Hospital, Boston, MA, 3Harvard School of Public Health, Boston, MA, 4Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 5Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Gout patients have an increased risk of type 2 diabetes mellitus (T2DM), cardiovascular disease (CVD), and chronic kidney disease (CKD); however, it is not…
  • Abstract Number: 2021 • 2017 ACR/ARHP Annual Meeting

    Reliability of Ultrasound Elementary Lesions in Gout: Results from an Inter- and Intra-Reading International Multicenter Exercise By 62 Sonographers

    Tomas Cazenave1, María Victoria Martire2, Christian A. Waimann3, Ana Bertoli4, Anthony Reginato5, Andy Abril6, Eliana Natalí Ayala Ledesma7, Maximiliano Bravo8, César Cefferino9, Carla Airoldi10, Carla Saucedo11, Carlos Pineda12, Gustavo Rodriguez Gil13, Cecilia Urquiola14, Cesar Graf15, Clarisa Sandobal16, M. Concepción Castillo Gallego17, Cristian Troitiño18, Cristina Hernandez-Diaz19, David Navarta20, Diana Peiteado21, MARIO DIAZ22, Diego Saaibi23, Henry Julio Colon Castillo24, Marwin Gutierrez25, Ana Laura Alvarez del Castillo Araujo26, Oscar Sedano27, Edith Alarcón28, Erika Catay8, Claudia Mora29, Eugenio De Miguel30, Félix Fernández Castillo31, Florencia Marengo32, Gabriel Aguilar33, Irene Monjo34, Javier Rosa35, José Francisco Díaz Coto36, Jorge Saavedra Muñoz37, Josefina Marin38, Lida Santiago39, Magalí Alva40, Manuella Lima Gomes Ochtrop41, Mara Guinsburg42, Mariana Benegas43, María Julia Santa Cruz44, Paula Kohan45, Natalia Estrella46, Mariana Pera47, Patricio Tate48, Priscila Marcaida49, Guillermo Py50, RICARDO PAVAO51, R Munoz-Louis52, Roser Areny Micas53, Rodolfo Arape54, Santiago Ruta35, María Soledad Gálvez Elkin55, Lorena Urioste56, Lina Saldarriaga Rivera57, OSCAR VEGA-HINOJOSA58, Lucio Ventura59, Walter J. Spindler60, Yvonne Rengel61, Maritza Quintero62 and Marcos G. Rosemffet63, 1Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 2Instituto Médico Platense, La Plata, Argentina, 3Hospital Dr. Hector Cura, Olavarria, Argentina, 4Instituto Reumatológico Strusberg, Córdoba, Argentina, 5Rhode Island Hospital, The Warren Alpert School of Medicine at Brown University, Providence, RI, 6Rheumatology, Mayo Clinic Florida, Jacksonville, FL, 7Hospital Nacional Arzobispo Loayza, Lima, Peru, 8Consultorios Moreno, Formosa, Argentina, 9HOSPITAL NACIONAL DOS DE MAYO, Lima, Peru, 10Hospital Provincial, Rosario, Argentina, 11Hospital Anita Elicagaray, Adolfo Gonzales Chaves, Argentina, 12Instituto Nacional de Rehabilitation, Mexico, Mexico, 13Hospital Municipal de Agudos "Dr Leónidas Lucero", Bahía Blanca, Argentina, 14Hospital Municipal Dr. Leónidas Lucero, Bahia Blanca, Argentina, 15Centro Médico Mitre, Paraná, Argentina, 16Hospital José María Cullen, Santa Fe, Argentina, 17Complejo Hospitalario Torrecárdenas, Almería, Spain, 18Reumatologia, Hospital Bernardino Rivadavia, CAPITAL FEDERAL, Argentina, 19Instituto Nacional de Rehabilitación, Mexico City, Mexico, 20Hospital Marcial Quiroga, San Juan, Argentina, 21Rheumatology, La Paz University Hospital, Madrid, Spain, 22Unidad de Reumatologia, Fundación Santa Fe de Bogotá, Bogota, Colombia, 23MEDICITY S.A.S, Bucaramanga, Colombia, 24RADES, Santo Domingo Este, Dominican Republic, 25Rheumatology, Instituto Nacional de Rehabilitación, Mexico City, Mexico, 26IMSS HES 25, Monterrey, Mexico, 27ULTRASOUND, ECOSERMEDIC, LIMA, Peru, 28Hospital San Juan de Lurigancho, Lima, Peru, 29Hospital Nacional Edgardo Rebagliati Martins, Lima, Peru, 30Rheumatology, University Hospital La Paz, IdiPaz, Madrid, Spain, 31Clínica Razetti, Barquisimeto, Venezuela (Bolivarian Republic of), 32Olavarria, Olavarria, Argentina, 33Centro de Diagnostico Rossi, Buenos Aires, Argentina, 34Rheumatology, Rheumatology. La Paz University Hospital, Spain., MADRID, Spain, 35Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, CABA, Argentina, 36Rheumatology, Hospital Clínica Bíblica, San José, Costa Rica, 37Hospital San Juan De Dios, Santiago, Chile, 38Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, 39Organizacion Medica de Investigacion, Buenos Aires, Argentina, 40Hospital Rebagliati, Jesús María, Peru, 41University Hospital Pedro Ernesto,, Rio de Janeiro,, Brazil, 42Rheumatology, Hospital Municipal Dr. Leónidas Lucero, Bahia Blanca, Argentina, 43Rheumatology Department, Sanatorio de la Providencia, Buenos Aires, Argentina, 44Section of Rheumatology, Hospital General de Agudos Dr. Enrique Tornú, Buenos Aires, Argentina, 45Hospital Dr. E. Tornu, Buenos Aires, Argentina, 46Consultorio Privado, Buenos Aires, Argentina, 47Hospital San Martín, La Plata, Argentina, 48Organizacion Médica de Investigación, Buenos Aires, Argentina, 49Hospital Rivadavia, Buenos Aires, Argentina, 50Servicio de Reumatología del Hospital Nacional de Clínicas, Córdoba., Cordoba, Argentina, 51GRE.ME.DA, Artigas, Uruguay, 52Rheumatology, Hospital Docente Padre Billini (HDPB), Santo Domingo, Dominican Republic, 53Hospital Dr. Félix Bulnes Cerda, Santiago, Chile, 54Centro Clinico la Isabelica, Valencia, Venezuela (Bolivarian Republic of), 55Instituto de Cardiología, Rosario, Argentina, 56Reumatología Diagnóstica Especializada, Santa Cruz de la Sie, Bolivia, 57Instituto Nacional de Rehabilitación, Mexico, Mexico, 58Clínica Reumacenter,, Juliaca, Peru, 59Instituto Nacional de Rehabilitación, Ciudad de México, Mexico, 60Centro Médico Privado de Reumatología, Tucuman, Argentina, 61Reumatologos en la Red, Caracas, Venezuela (Bolivarian Republic of), 62Instituto Autónomo Hospital Universitario de Los Andes, Universidad de Los Andes, Mérida, Venezuela, 63Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina

    Background/Purpose: The OMERACT ultrasound (US) Gout Task Force has defined four US elementary lesions to evaluate patients with gout: double contour (DC), aggregates, tophus and…
  • Abstract Number: 2052 • 2017 ACR/ARHP Annual Meeting

    Apply Musculoskeletal Ultrasonography to Predict Chronic Gouty Arthritis in Patients with Chronic Kidney Diseases

    Zheng-Hao Huang1, Chi-Ching Chang2, En Chao3, Hui-Hsun Chiang4, Shu-Yi Lin5, Kun-Lin Wu6, Hsiang-Cheng Chen5, Shi-Jye Chu5, San-Yuan Kao5, Tsung-Yun Hou5, Feng-Cheng Liu5, Chen-Hung Chen7, Deh-Ming Chang8 and Chun-Chi Lu9, 1Division of Rheumatology, Immunology and Allergy, Department of Internal Medicine, Kaohsiung Armed Forces General Hospital; Tri-service general hospital, National Defense Medical Center, Taipei, Taiwan, 2Taipei Medical University Hospital, Taipei, Taiwan, 3Tri-Service General Hospital Songshan Branch, Taipei, Taiwan, 4School of Nursing, National Defense Medical Center, Taipei, Taiwan, 5Tri-Service General Hospital, Taipei, Taiwan, 6Armed Forces Taoyuan General Hospital, Taipei, Taiwan, 7Taipei Tzu Chi hospital, Taipei, Taiwan, 8Taipei Veterans General Hospital, Taipei, Taiwan, 9University of Washington; Tri-Service General Hopsital, National Defense Medical Center, Seattle, WA

    Background/Purpose: Gouty arthritis, caused by the deposition of monosodium urate (MSU) monohydrate crystals at joints, is comprised of multiple inflammatory processes in synovium, tendons, cartilages…
  • Abstract Number: 2054 • 2017 ACR/ARHP Annual Meeting

    Rapid Tophus Resolution in Chronic Refractory Gout Patients Treated with Pegloticase

    Brian F. Mandell1, Herbert S. B. Baraf2, Anthony Yeo3 and Peter E. Lipsky4, 1Rheumatology, Cleveland Clinic, Cleveland, OH, 2The Center for Rheumatology and Bone Research, Wheaton, MD, 3Horizon Pharma, Lake Forest, IL, 4AMPEL BioSolutions, LLC, Charlottesville, VA

      Background/Purpose: It has been suggested that the velocity of resolution of tophi in chronic tophaceous gout is related to serum uric acid (sUA) levels.1 However,…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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