ACR Meeting Abstracts

ACR Meeting Abstracts

  • Home
  • Meetings Archive
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018 ACR/ARHP Annual Meeting
    • 2017 ACR/ARHP Annual Meeting
    • 2017 ACR/ARHP PRSYM
    • 2016-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • Register
    • View and print all favorites
    • Clear all your favorites
  • Meeting Resource Center

Abstract Number: 1094

Work Productivity and Healthcare Utilization in Patients with Fibromyalgia and Comorbid Depression Taking Antidepressant Medication

Jaren Landen1, Claire Burbridge2, Elizabeth Masters3, Pritha Bhadra Brown4, Joseph Scavone1, Birol Emir4, Richard Vissing5, Andrew Clair4 and Lynne Pauer6, 1Pfizer Inc, Groton, CT, 2Pfizer Ltd, Walton Oaks, United Kingdom, 3Health Economics and Outcomes Research, Pfizer Inc, New York, NY, 4Pfizer Inc, New York, NY, 5Pfizer Inc, Louisville, KY, 6445 Eastern Point Road, Pfizer Inc, Groton, CT

Meeting: 2014 ACR/ARHP Annual Meeting

Keywords: depression, fibromyalgia, Health care cost, pain and work

  • Tweet
  • Email
  • Print
Save to PDF
Session Information

Session Title: Fibromyalgia, Soft Tissue Disorders, Regional and Specific Clinical Pain Syndromes: Clinical Focus

Session Type: Abstract Submissions (ACR)

Background/Purpose Patients with fibromyalgia (FM) experience pain, sleep disruption, fatigue, and other symptoms that limit activity, impacting work productivity and increasing healthcare utilization. Here, we describe the burden of FM on work productivity and healthcare utilization in patients with FM taking antidepressant medication for their comorbid depression.

Methods Patients from 38 centers in the United States, Europe (Italy, Spain), and Canada were enrolled in a phase 3 study of pregabalin efficacy and safety (NCT01432236). Patients with FM aged ≥18 years were taking a stable dose of a single selective serotonin reuptake inhibitor or serotonin/norepinephrine reuptake inhibitor for their comorbid depression for ≥2 months prior to randomization. FM-related work productivity and healthcare utilization were assessed at randomization. Work productivity over the preceding 7 days was measured using the Work Productivity and Activity Impairment:Fibromyalgia Symptoms (WPAI:FMS) questionnaire, a self-reported measure of FM-related absenteeism (work time missed), presenteeism (impairment while working), overall work impairment (absenteeism plus presenteeism), and activity impairment (impairment of regular activities other than work). Absenteeism, presenteeism, and overall work impairment were measured for employed individuals only. Each score is expressed as a percentage, higher scores indicating less productivity and greater impairment. Healthcare utilization related to FM in the preceding 3 months was measured using a self-reported Healthcare Utilization Assessment questionnaire that captured: number of healthcare professional (HCP) visits, hospitalizations, and emergency room (ER) visits; use of physical treatments and supplements; time other people spent providing help with activities of daily living without receiving payment; and out of pocket expenses for physical treatments, supplements, prescription and non-prescription medications, and professional services to assist with activities of daily living.

Results 193 patients were evaluated at randomization. FM-related work productivity scores (mean ± SD) in the preceding 7 days were: absenteeism 15.2 ± 25.4% (n = 86), presenteeism 54.0 ± 21.5% (n = 83), overall work impairment 58.0 ± 23.4% (n = 82), and activity impairment 65.0 ± 18.8% (n = 193). In the preceding 3 months, the total number (mean ± SD) of HCP visits related to FM was 5.0 ± 6.6. There were no hospitalizations but 12 (6.2%) patients visited the ER. 67 (34.7%) and 61 (31.6%) patients used physical treatments and supplements, respectively. The number of hours (mean ± SD) other people spent providing help without payment was 50.4 ± 98.1. In patients who incurred out of pocket expenses in the preceding 3 months, total (mean [range]) expenditure was $US 307.12 (0–5,300; n = 110), EUR 410.43 (0–2,485; n = 49), and $CAN 211.26 (0–1,000; n = 19).

Conclusion FM affects work productivity and regular activities other than work in patients with FM taking antidepressant medication for their comorbid depression. In these patients, FM is associated with substantial healthcare utilization, and generates considerable out of pocket expenses.


Disclosure:

J. Landen,

Pfizer Inc,

3,

Pfizer Inc,

1;

C. Burbridge,

Pfizer Inc,

3,

Pfizer Inc,

1;

E. Masters,

Pfizer Inc,

3,

Pfizer Inc,

1;

P. Bhadra Brown,

Pfizer Inc,

3,

Pfizer Inc,

1;

J. Scavone,

Pfizer Inc.,

1,

Pfizer Inc.,

3;

B. Emir,

Pfizer Inc.,

1,

Pfizer Inc.,

3;

R. Vissing,

Pfizer Inc,

3,

Pfizer Inc,

1;

A. Clair,

Pfizer Inc,

3,

Pfizer Inc,

1;

L. Pauer,

Pfizer Inc.,

1,

Pfizer Inc.,

3.

  • Tweet
  • Email
  • Print
Save to PDF

« Back to 2014 ACR/ARHP Annual Meeting

ACR Meeting Abstracts - https://acrabstracts.org/abstract/work-productivity-and-healthcare-utilization-in-patients-with-fibromyalgia-and-comorbid-depression-taking-antidepressant-medication/

Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

ACR Convergence: Where Rheumatology Meets. All Virtual. November 5-9.

ACR Pediatric Rheumatology Symposium 2020

© COPYRIGHT 2021 AMERICAN COLLEGE OF RHEUMATOLOGY

Wiley

  • Home
  • Meetings Archive
  • Advanced Search
  • Meeting Resource Center
  • Online Journal
  • Privacy Policy
  • Permissions Policies
loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.