ACR Meeting Abstracts

ACR Meeting Abstracts

Abstract Number: 61

Which Juvenile Idiopathic Arthritis patient is more likely to have Temporomandibular Joint involvement?

shelly abramowicz1, joshua levy2, Curtis Travers3, Sampath Prahalad4 and Sheila Angeles-Han5, 1Surgery, Emory University/Children's Healthcare of Atlanta, atlanta, GA, 2Surgery, Emory University, atlanta, GA, 3Pediatrics, Emory University School of Medicine, Atlanta, GA, 4Pediatrics, Emory Children's Center, Atlanta, GA, 5Department of Pediatrics, Cincinnati Children's Hospital, Cincinnati, OH

Meeting: 2017 Pediatric Rheumatology Symposium

Keywords:

Session Information

Date: Thursday, May 18, 2017

Title: Clinical and Therapeutic Poster Session

Session Type: Abstract Submissions

Session Time: 5:30PM-7:00PM

Background/Purpose: Juvenile Idiopathic Arthritis (JIA) affects approximately 300,000 children in the United States. Temporomandibular joint (TMJ) involvement in children with JIA can lead to decreased mandibular growth. This may result in jaw asymmetry, malocclusion, and/or limited mouth opening. The purpose of this study was to characterize a population of patients with TMJ involvement and JIA in a single center cohort.

Methods: A retrospective analysis of patients diagnosed with JIA, who were concurrently enrolled in a study of uveitis in JIA at Children’s Healthcare of Atlanta from 2012 to 2016. Children who also endorsed jaw symptoms in the past or during enrollment in the study were included. This study collected information regarding gender, race, JIA subtype, age at first jaw complaint, RF status, ANA status, HLA-B27 status, and involvement of all joints (in addition to TMJ).

Results: This cohort consisted of 470 patients. Of them, 60 patients (52 female, 8 males) with a mean age of 13 years (range, 5 to 18) met inclusion criteria. Patients were Caucasian (43, 71.7%), Hispanic (7, 11.7%), Black (4, 6.7%), or other (6, 10%). Patients had Poly RF negative (19, 31.7%), Oligoarticular Persistent (15, 25.0%), Enthesitis Related (9, 15%), Oligoarticular Extended (7, 11.7%), Poly RF Positive (n, 6.7%), Systemic (3, 5%), Psoriatic (2, 3.3%), Undifferentiated (1, 1.7%). Of children with TMJ involvement, 38 (63%) had involvement of other joints. Patients were RF positive (9, 18.4 %), ANA positive (26, 43.3%), and/or HLA-B27 positive (9, 18.4%). In addition to TMJ, at the time of data collection, other involved joints were: none (22, 36.7%), fingers (18,30.0%), knees (18,30.0%), wrists (14,23.3%) and other (37, 61.6%).

Conclusion: In our cohort, sixty patients (12.8%) experienced TMJ symptoms either prior to or during their enrollment in the study. In this study population, patients who are female, white, RF negative, HLA-B27 negative, ANA negative, Poly RF negative subtype, and have involvement of other joints have a higher likelihood of having jaw symptoms.

Disclosure: S. abramowicz, None; J. levy, None; C. Travers, None; S. Prahalad, None; S. Angeles-Han, None.

To cite this abstract in AMA style:

abramowicz S, levy J, Travers C, Prahalad S, Angeles-Han S. Which Juvenile Idiopathic Arthritis patient is more likely to have Temporomandibular Joint involvement? [abstract]. Arthritis Rheumatol. 2017; 69 (suppl 4). https://acrabstracts.org/abstract/which-juvenile-idiopathic-arthritis-patient-is-more-likely-to-have-temporomandibular-joint-involvement/. Accessed .

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