ACR Meeting Abstracts

ACR Meeting Abstracts

  • Home
  • Meetings Archive
    • 2019 ACR/ARP Annual Meeting
    • 2018 ACR/ARHP Annual Meeting
    • 2017 ACR/ARHP Annual Meeting
    • 2017 ACR/ARHP PRSYM
    • 2016 ACR/ARHP Annual Meeting
    • 2015 ACR/ARHP Annual Meeting
    • 2014 ACR/ARHP Annual Meeting
    • 2013 ACR/ARHP Annual Meeting
    • 2012 ACR/ARHP Annual Meeting
    • 2011 ACR/ARHP Annual Meeting
    • 2010 ACR/ARHP Annual Meeting
    • 2009 ACR/ARHP Annual Meeting
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • Register
    • View and print all favorites
    • Clear all your favorites
  • Meeting Resource Center

Abstract Number: 2477

Which Is the Best Measure for Rheumatoid Arthritis Disease Activity? a Head to Head Comparison of the Six American College of Rheumatology Recommended Disease Activity Measures

Mamatha Katikaneni1, Sunny Patel2, Arina Garg2, Madiha Tariq2, Sebastian Wilk2, Khagendra Dahal3, Robert Walter3 and Samina Hayat4, 1Rheumatology, Louisiana State University Health Sciences Center, Shreveport, Shreveport, LA, 2Louisiana State University Health Sciences Center, Shreveport, Shreveport, LA, 3Medicine, Louisiana State University Health Sciences Center, Shreveport, Shreveport, LA, 4Rheumatology/Internal Medicine, Louisiana State University Health Sciences Center, Shreveport, Shreveport, LA

Meeting: 2018 ACR/ARHP Annual Meeting

Keywords: Disease Activity and rheumatoid arthritis (RA)

  • Tweet
  • Email
  • Print
Save to PDF
Session Information

Date: Tuesday, October 23, 2018

Session Title: Rheumatoid Arthritis – Diagnosis, Manifestations, and Outcomes Poster III: Complications of Therapy, Outcomes, and Measures

Session Type: ACR Poster Session C

Session Time: 9:00AM-11:00AM

Background/Purpose:

Treat-to-target is the recommended strategy for the appropriate management of Rheumatoid arthritis (RA) which involves regular assessment and monitoring of disease activity using a validated measure. Currently 6 measures are recommended by the American College of Rheumatology (ACR) for use in clinical practice.

1.      Clinical Disease Activity Index (CDAI)

2.      Disease activity Score with 28 Joint Counts (DAS 28)

3.      Patient Activity scale (PAS)

4.      Patient Activity Scale II (PAS II)

5.      Routine Assessment of Patient Index Data- 3 measures (RAPID–3)

6.      Simplified Disease Activity Index (SDAI).

The table lists the key features of each:

Methods:

50 patients diagnosed with RA based on ACR/EULAR 2010 criteria were consented and asked to fill a questionnaire during that visit and follow up visits making a total of 100 encounters. The questionnaire included questions for the Health Assessment Questionnaire (HAQ), HAQ II and the Multidimensional Health Assessment Questionnaire (MDHAQ) along with the patient global Assessment. The treating physician filled out the Provider Global Assessment (0 – 10), 28 joint count for swollen and tender joints and documented their clinical impression (1 – stable, 2- mild flare, 3- moderate flare or 4- severe flare). The Disease activity measures were calculated using the ACR calculator and recorded ( 1- remission, 2- Low disease activity, 3- Moderate disease activity and 4- high disease activity). The Pearson correlation coefficient was calculated for each of the six markers compared to the physician’s clinical impression.

Results:

Patient characteristics

The best correlation was found to be with CDAI (0.84), followed by DAS 28 CRP and SDAI (0.79), then PAS (0.53), PAS II (0.47) and finally RAPID-3 (0.39).

Conclusion:

The PAS, PAS II and RAPID-3 which are patient reported are not very well correlated possibly due to over-estimation of symptoms by patients for various reasons. The dependence of SDAI and DAS-28 on CRP value makes them slightly less favorable in practice since the lab value may be reported after the patient encounter has been completed, thus making it less efficient to calculate, document and utilize. CDAI is the best correlated and due to the fact that it does not require any lab evaluation, it is evidently the best measure to adopt.

 


Disclosure: M. Katikaneni, None; S. Patel, None; A. Garg, None; M. Tariq, None; S. Wilk, None; K. Dahal, None; R. Walter, None; S. Hayat, None.

To cite this abstract in AMA style:

Katikaneni M, Patel S, Garg A, Tariq M, Wilk S, Dahal K, Walter R, Hayat S. Which Is the Best Measure for Rheumatoid Arthritis Disease Activity? a Head to Head Comparison of the Six American College of Rheumatology Recommended Disease Activity Measures [abstract]. Arthritis Rheumatol. 2018; 70 (suppl 10). https://acrabstracts.org/abstract/which-is-the-best-measure-for-rheumatoid-arthritis-disease-activity-a-head-to-head-comparison-of-the-six-american-college-of-rheumatology-recommended-disease-activity-measures/. Accessed December 15, 2019.
  • Tweet
  • Email
  • Print
Save to PDF

« Back to 2018 ACR/ARHP Annual Meeting

ACR Meeting Abstracts - https://acrabstracts.org/abstract/which-is-the-best-measure-for-rheumatoid-arthritis-disease-activity-a-head-to-head-comparison-of-the-six-american-college-of-rheumatology-recommended-disease-activity-measures/

Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

Annual Meeting in Atlanta, Georgia

© COPYRIGHT 2019 AMERICAN COLLEGE OF RHEUMATOLOGY

Wiley

  • Home
  • Meetings Archive
  • Advanced Search
  • Meeting Resource Center
  • Online Journal
  • Privacy Policy
  • Permissions Policies
loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.