Session Title: Imaging of Rheumatic Diseases - Poster II: XR/CT/PET/MRI
Session Type: ACR Poster Session B
Session Time: 9:00AM-11:00AM
Background/Purpose: The purpose of this study was to investigate bone microarchitecture variables of cadaveric vertebrae using ultra-high field MRI (7 Tesla).
Methods: Twenty four vertebrae (L2, L3, L4) from eight cadavers were studied using 7 Tesla MRI. Their Bone Mineral Density (BMD) were investigated using dual energy X Ray absorptiometry. Then, all specimens underwent mechanical compression tests to failure and the failure load (in Newton) and constraint (in Mpa) were measured. Bone Volume Fraction (BV/TV), Trabecular Thickness (Tb.Th), and Trabecular Spacing (Tb.Sp) were measured in MR images using a Digital topological analysis (Bone J). Measurements were performed by two observators in order to characterize the inter-rater reliability. Statistical analyses were performed using SPSS. Correlations between variables were analyzed using Spearman correlations and Stepwise regression. A p value of 0.05 was considered as significant.
To cite this abstract in AMA style:Guenoun D, Foure A, Pithioux M, Guis S, Lecorroller T, Chabrand P, Mattei JP, Bernard M, Champsaur P, Bendahan D. Ultra-High Field MRI and Biomechanical Investigation of Vertebral Bone Microarchitecture [abstract]. Arthritis Rheumatol. 2016; 68 (suppl 10). https://acrabstracts.org/abstract/ultra-high-field-mri-and-biomechanical-investigation-of-vertebral-bone-microarchitecture/. Accessed November 19, 2019.
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ACR Meeting Abstracts - https://acrabstracts.org/abstract/ultra-high-field-mri-and-biomechanical-investigation-of-vertebral-bone-microarchitecture/