Session Information
Date: Tuesday, November 10, 2015
Title: Health Services Research Poster III: Patient Reported Outcomes, Patient Education and Preferences
Session Type: ACR Poster Session C
Session Time: 9:00AM-11:00AM
Background/Purpose: The Systemic Lupus Erythematosus Quality of Life Questionnaire (L-QoL) is a disease-specific measure of needs-based quality of life developed in the United Kingdom (1).
Aim: To assess the validity and reliability of the L-QoL in a Turkish population.
Methods: The L-QoL was translated into Turkish using the dual-panel process. Patients with SLE were recruited from 4 different rheumatology clinics. L-QoL administered twice with 3-4 weeks of interval to assess the test-retest reliability (intraclass correlation coefficient). Face validity was assessed via cognitive debriefing interviews with SLE patients. The convergent and divergent validities were assesed for determine the construct properties of the questionnaire. The relation of the L-QoL with subsets of Nottingham Health Profile (NHP) (energy level, pain, emotional reactions, sleep, social isolation, physical mobility) and Health Assessment Questionnaire (HAQ) were assessed for convergent validity. The relation of the L-QoL with non functional parameters such as age, disease duration, perceived general health and SLEDAI were assessed for divergent validity. Spearman’s correlation coeficient (rho) was used to assessed the relation between quantitative parameters. P<0.05 was accepted as significant.
Results: Fifty-five SLE patients (53 female, 2 male) with 43.55 (SD:14.33) mean of age were recruited into the study. Test–retest reliability was very good (0.87), indicating low random measurement error for the scale. The measure was well accepted and the items considered understandable and relevant which showed the face validity of Turkish version of the questionnaire. The L-QoL has good correlation with subsets of NHP and HAQ were suggesting the measure assess related but distinct constructs (convergent). Its poor and not significant correlation with non functional parameters (divergent) showed its discriminative properties (Table).
|
Convergent validity of L-QoL |
Spearman’s (rho) |
Significance (p) |
|
NHP-energy level |
0.52 |
<0.0001 |
|
NHP-pain |
0.64 |
<0.0001 |
|
NHP-emotional reactions |
0.72 |
<0.0001 |
|
NHP-sleep |
0.65 |
<0.0001 |
|
NHP-social isolation |
0.60 |
<0.0001 |
|
NHP-physical mobility |
0.53 |
<0.0001 |
|
HAQ |
0.62 |
<0.0001 |
|
Divergent validity of L-QoL |
Spearman’s (rho) |
Significance (p) |
|
Age |
0.19 |
0.1640 |
|
Disease duration |
0.18 |
0.1930 |
|
Perceived general health |
0.32 |
0.0460 |
|
SLEDAI |
0.29 |
0.1000 |
Conclusion: The Turkish version of L-QoL has good reliability and validity properties. It is practical and useful scale to assess the quality of life in SLE patients in Turkish population
1. L C Doward LC, McKenna SP, Whalley D et al. The development of the L-QoL: a quality-of-life instrument specific to systemic lupus erythematosus. Ann Rheum Dis 2009;68:196–200.
To cite this abstract in AMA style:
Duruoz MT, Sanal Top C, Sezer I, Yılmaz F, Ünal C, Baklacioglu HS, Ulutatar F, Atagunduz P. The Turkish Validity and Reliability of the Systemic Lupus Erythematosus Quality of Life Questionnaire (L-QoL) [abstract]. Arthritis Rheumatol. 2015; 67 (suppl 10). https://acrabstracts.org/abstract/the-turkish-validity-and-reliability-of-the-systemic-lupus-erythematosus-quality-of-life-questionnaire-l-qol/. Accessed .« Back to 2015 ACR/ARHP Annual Meeting
ACR Meeting Abstracts - https://acrabstracts.org/abstract/the-turkish-validity-and-reliability-of-the-systemic-lupus-erythematosus-quality-of-life-questionnaire-l-qol/