Session Type: ACR Poster Session B
Session Time: 9:00AM-11:00AM
Giant cell arteritis (GCA) is the most common systemic vasculitis in adults aged 50 years or above. Annual incidence rates vary widely from 6.9–76.6 per 105 of adults in this age group, depending on the region.1 Our aim was to determine the incidence rate of GCA in our population.
Methods: We prospectively collected incident cases of GCA from January 1st 2011 to December 31st 2014 at our department of rheumatology which is a part of an integrated secondary/tertiary university teaching hospital that is the only referral center serving a region representing approximately a quarter of the national adult population. Additionally, newly diagnosed cases of GCA between January 1st 2009 and December 31st 2010 were retrospectively identified by searching the electronic patient records for ICD-10 codes M31.5 and M31.6 at our department. The retrospective approach and search strategy was also applied on electronic medical records at the departments of infectious diseases and ophthalmology between January 1st 2009 and December 31st 2014. To further reduce possibility of underreporting, the attached medical faculty’s Institute of Pathology provided a list of all temporal artery biopsies examined during the observation period which were then cross-referenced with the hospital’s electronic medical records. Annual incidence rate for GCA was then calculated.
During the six year observation period we identified 137 new cases of GCA (68% female; mean (IQR) age 75.9 (11.1) years) from a well-defined adult white Caucasian population of 235,596 inhabitants aged 50 or above. The temporal artery biopsy was consistent with GCA, negative or not performed in 80.2 %, 19.8 %, and 8.0 % of cases, respectively. Thus, the average six years annual incidence of GCA in our population is 9.7 (95 % CI 8.1–15.5), the highest was in 2010 (11.7 (95% CI 7.7-17.1)), and the lowest in 2013 (7.5 (95% CI 4.4-11.8)) per 105 adults aged 50 or above.
The average annual incidence rate of 9.7 per 105 adults aged 50 or above makes GCA the most common systemic vasculitis in our population.
1. Gonzalez-Gay MA, Vazquez-Rodriguez TR, Lopez-Diaz MJ et al. Epidemiology of Giant Cell Arteritis and Polymyalgia Rheumatica. Arthritis Rheum 2009;61:1454-61.
To cite this abstract in AMA style:Potocnik N, Hocevar A, Rotar Z, Pizem J, Hawlina M, Fakin A, Tomšič M. The Incidence Rate of Giant Cell Arteritis in Slovenia [abstract]. Arthritis Rheumatol. 2015; 67 (suppl 10). https://acrabstracts.org/abstract/the-incidence-rate-of-giant-cell-arteritis-in-slovenia/. Accessed February 27, 2020.
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