Session Type: ACR Poster Session B
Session Time: 9:00AM-11:00AM
Background/Purpose: Reactive Arthritis (ReA) is an inflammatory spondyloarthritis occurring after infection at a distant site. Chlamydia trachomatis is proposed to be the most common cause of ReA, yet the incidence of sexually-acquired ReA (SARA) has not been well established. We carried out a systematic literature review to collate and critically evaluate the published evidence regarding the incidence of SARA.
Methods: MEDLINE and EMBASE databases were searched using free-text and MeSH terms relating to infection and ReA. The title and abstract of articles returned were screened independently by two reviewers and potentially relevant articles assessed in full. Data were extracted from relevant articles and a risk of bias assessment carried out using a validated tool. Heterogeneity of study methodology and results precluded meta-analysis.
Results: The search yielded a total of 11680 articles, and a further 17 were identified from review articles. After screening, 55 papers were assessed in full, from which 3 met the relevant inclusion criteria for the review. The studies reported an incidence of SARA of 3.0% – 8.1% and were of low to moderate quality.
Conclusion: More studies are required to address the lack of data regarding the incidence of SARA. Specific and sensitive classification criteria must be developed in order for consistent classification and valid conclusions to be drawn. In clinical practice, it is recommended clinicians discuss the possibility of ReA developing at the time of STI diagnosis, and to encourage patients to return if they experience any relevant symptoms.
To cite this abstract in AMA style:Denison H, Curtis E, Clynes M, Bromhead C, Dennison E, Grainger R. The Incidence of Sexually Acquired Reactive Arthritis: A Systematic Literature Review [abstract]. Arthritis Rheumatol. 2016; 68 (suppl 10). https://acrabstracts.org/abstract/the-incidence-of-sexually-acquired-reactive-arthritis-a-systematic-literature-review/. Accessed October 27, 2021.
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