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Abstract Number: 1309

The Incidence of Sexually Acquired Reactive Arthritis: A Systematic Literature Review

Hayley Denison1, Elizabeth Curtis2, Michael Clynes2, Collette Bromhead3, Elaine Dennison2,4 and Rebecca Grainger5, 1School of Biological Sciences, Victoria University of Wellington, Welington, New Zealand, 2MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, United Kingdom, 3Massey Institute of Food Science and Technology, Massey University, Wellington, New Zealand, 4School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand, 5University of Otago Wellington, Wellington, New Zealand

Meeting: 2016 ACR/ARHP Annual Meeting

Date of first publication: September 28, 2016

Keywords: Infection and reactive arthritis

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Session Information

Date: Monday, November 14, 2016

Title: Infection-related Rheumatic Disease - Poster

Session Type: ACR Poster Session B

Session Time: 9:00AM-11:00AM

Background/Purpose: Reactive Arthritis (ReA) is an inflammatory spondyloarthritis occurring after infection at a distant site. Chlamydia trachomatis is proposed to be the most common cause of ReA, yet the incidence of sexually-acquired ReA (SARA) has not been well established. We carried out a systematic literature review to collate and critically evaluate the published evidence regarding the incidence of SARA.

Methods: MEDLINE and EMBASE databases were searched using free-text and MeSH terms relating to infection and ReA. The title and abstract of articles returned were screened independently by two reviewers and potentially relevant articles assessed in full. Data were extracted from relevant articles and a risk of bias assessment carried out using a validated tool. Heterogeneity of study methodology and results precluded meta-analysis.

Results: The search yielded a total of 11680 articles, and a further 17 were identified from review articles. After screening, 55 papers were assessed in full, from which 3 met the relevant inclusion criteria for the review. The studies reported an incidence of SARA of 3.0% – 8.1% and were of low to moderate quality.

Conclusion: More studies are required to address the lack of data regarding the incidence of SARA. Specific and sensitive classification criteria must be developed in order for consistent classification and valid conclusions to be drawn. In clinical practice, it is recommended clinicians discuss the possibility of ReA developing at the time of STI diagnosis, and to encourage patients to return if they experience any relevant symptoms.


Disclosure: H. Denison, None; E. Curtis, None; M. Clynes, None; C. Bromhead, None; E. Dennison, None; R. Grainger, None.

To cite this abstract in AMA style:

Denison H, Curtis E, Clynes M, Bromhead C, Dennison E, Grainger R. The Incidence of Sexually Acquired Reactive Arthritis: A Systematic Literature Review [abstract]. Arthritis Rheumatol. 2016; 68 (suppl 10). https://acrabstracts.org/abstract/the-incidence-of-sexually-acquired-reactive-arthritis-a-systematic-literature-review/. Accessed .
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