ACR Meeting Abstracts

ACR Meeting Abstracts

Abstract Number: 978

Socioeconomic Status Measures Are Associated with Increasing Pain, Stiffness and Physical Function Among Individuals with Knee and Hip Osteoarthritis

Rebecca J. Cleveland1, Jordan B. Renner2, Joanne M. Jordan3 and Leigh F. Callahan4, 1Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2University of North Carolina Department of Radiology, Chapel Hill, NC, 3University of North Carolina Dept of Epidemiology, Chapel Hill, NC, 4Thurston Arthritis Res Ctr, University of North Carolina, Chapel Hill, NC

Meeting: 2014 ACR/ARHP Annual Meeting

Keywords: , ,

Session Information

Title: Osteoarthritis

Session Type: Abstract Submissions (ARHP)

Background/Purpose The determinants of disability progression (DP) among those with knee and/or hip osteoarthritis (OA) are not well known. Our aim was to explore whether socioeconomic status (SES) measures were associated with DP at follow-up (FU) in the Johnston County Osteoarthritis Project (JoCo OA).

Methods Analyses were carried out among individuals with radiographic knee and/or hip OA (rOA) aged ≥45 years who participated in TIME 1 (T1; 1999-2004), which included those who entered the cohort during the original study enrollment who returned for their first follow-up, and new enrolls recruited for cohort enrichment. Follow-up was assessed at TIME 2 (T2 FU; 2006-2010). DP was assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) which includes Pain, Stiffness and Physical Function Subscales. DP was defined as an increase from T1 to T2 FU of ≥10 in the WOMAC total score, or any increase in a subscale score. SES measures were education (no high school diploma [Results There were 796 individuals with knee and/or hip rOA from T1 who returned at T2 FU. The mean age was 64.6 years, 66.3% were female, 30.7% African American, and mean BMI was 31.8 kg/m2. At T2 FU, there was increased disability in 26.8% of individuals with knee rOA and 21.8% of individuals with hip rOA. Analyses including all individuals with knee and/or hip rOA showed that individuals with Conclusion We report that individuals with lower education and non-professional occupation were more likely to have DP from T1 to T2 FU, associations that remained after adjustment for other SES measures. Our results suggest that SES may have an influence on DP, findings which may help clinicians in develop personalized OA management programs for individuals with low SES measures.


Table 1. Adjusted† odds ratios (OR) and 95% confidence intervals (CI) for the association between SES measures and

WOMAC score increase  between the first and second follow-up

 

Knee and/or Hip rOA

Only Hip rOA

Only Knee rOA

OR (95% CI)‡

OR (95% CI)µ

OR (95% CI)¥

 

n=796

n=289

n=317

WOMAC Total Increase ≥10

 

 

 

€

1.96 (1.28-3.00)

1.59 (0.75-3.37)

2.86 (1.45-5.67)

Non-Professional Occupation

1.10 (0.74-1.64)

1.96 (0.98-3.91)

0.80 (0.43-1.51)

Block Group Poverty >20%‽

1.07 (0.74-1.55)

1.26 (0.66-2.39)

1.02 (0.56-1.83)

 

 

 

 

WOMAC Stiffness Increase

 

 

 

€

1.30 (0.85-1.97)

0.81 (0.37-1.78)

2.18 (1.13-4.20)

Non-Professional Occupation

0.99 (0.68-1.45)

2.03 (1.03-4.01)

0.59 (0.32-1.07)

Block Group Poverty >20%‽

0.87 (0.61-1.25)

0.97 (0.51-1.85)

0.93 (0.53-1.64)

 

 

 

 

WOMAC Pain Increase

 

 

 

€

1.50 (1.01-2.21)

1.34 (0.67-2.67)

2.09 (1.11-3.96)

Non-Professional Occupation

1.08 (0.76-1.53)

1.86 (1.01-3.43)

0.71 (0.40-1.24)

Block Group Poverty >20%‽

0.90 (0.64-1.25)

1.12 (0.63-1.97)

0.72 (0.42-1.24)

 

 

 

 

WOMAC Physical Function Increase

 

 

 

€

1.50 (1.02-2.20)

1.00 (0.50-1.98)

2.65 (1.40-5.00)

Non-Professional Occupation

1.13 (0.80-1.60)

1.90 (1.04-3.47)

0.72 (0.41-1.26)

Block Group Poverty >20%‽

0.83 (0.60-1.15)

0.69 (0.39-1.23)

1.05 (0.61-1.80)

†Mutually adjusted for education, occupation, poverty

 

‡Additionally adjusted for age, gender, hip & knee injury, BMI and smoking

 

µAdditionally adjusted for age, gender, hip injury, BMI and smoking

 

¥Additionally adjusted for age, gender, knee injury, BMI and smoking

 

€Comparing  

Comparing non-professional occupation vs. professional occupation

 

‽Comparing block group poverty ≥20% vs. <20%

 

Disclosure:

R. J. Cleveland,
None;

J. B. Renner,
None;

J. M. Jordan,

Algynomics,

5,

Samumed,

5,

Flexion,

5,

ClearView Healthcare Partners,

5,

Trinity Partners, LLC,

5;

L. F. Callahan,
None.

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