Session Type: ACR Poster Session C
Session Time: 9:00AM-11:00AM
Background/Purpose: Patient reported outcomes are important to measure the effectiveness of non-pharmacological and pharmacological interventions. The goal of PROMIS is to develop standardized items banks for use across different conditions . The PROMIS-29, which assesses difficulty with activities and symptom severity, has been shown to be valid for patients with SSc . However, other PROMIS measures, such as the PROMIS Self-Efficacy scales may be important to the management of a chronic disease such as SSc.
Methods: Participants with SSc, who were part of a larger study on self-management, completed the PROMIS Self-Efficacy Scales and PROMIS-29. PROMIS-29 includes physical function, anxiety, depression, fatigue, sleep disturbance, pain interference, and satisfaction with social roles, while the PROMIS self-efficacy scales measure self-efficacy for emotions, symptoms, daily activities, social interactions, and medication and treatment. Patients also completed a demographic questionnaire and the Patient Health Questionnaire (PHQ). Significant differences in PROMIS and PROMIS-29 scales between subgroups were determined using t-tests, Wilcoxon tests or Fisher’s exact tests depending on the distribution of the variables. t-tests were used for variables that were approximately normally distributed, non-parametric Wilcoxon tests for non-normally distributed variables and Fisher’s exact tests for discrete, categorical variables.
267 participants completed the questionnaires. Mean age was 53.7 years, disease duration from onset of first SSc symptoms was 11.9 yrs. 91% were women and 82.8 % were white. There were significant differences in all PROMIS self-efficacy and all PROMIS-29 scale scores between patients without depressed mood (PHQ-8 <10) vs depressed mood (PHQ-8 >10). Married patients had significantly better PROMS Self-Efficacy for social interaction and PROMIS-29 scores for social role, anxiety, depression, and fatigue. Participants who were employed full time had significantly better scores on the PROMIS self-efficacy scales for managing symptoms, daily activities and medications and treatment compared to participants not employed full time. For the PROMIS-29, significant differences were found for scales relative to physical function, social role, depression, fatigue, pain interference and pain intensity.
Disease duration (< median value or > median value) significantly affected PROMIS self-efficacy scales only with respect to managing daily activities and physical function. No significance differences in PROMIS self-efficacy or PROMIS-29 scores were observed between patients with different subtypes of SSc (diffuse vs limited/sine), education level (< or > 12th grade) or race (white versus non-white).
Patients with SSc who did not have depressed mood, had education above the 12th grade, were married and employed full time had higher PROMIS-29 and PROMIS Self-Efficacy scores.
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To cite this abstract in AMA style:Poole JL, Berrocal VJ, Serrano J, Bush E, Khanna D. Performance of Patient-Reported Outcomes Measurement Information Systems (PROMIS) Promis-29 and Promis Self-Efficacy in Systemic Sclerosis (SSc) [abstract]. Arthritis Rheumatol. 2017; 69 (suppl 10). https://acrabstracts.org/abstract/performance-of-patient-reported-outcomes-measurement-information-systems-promis-promis-29-and-promis-self-efficacy-in-systemic-sclerosis-ssc/. Accessed July 11, 2020.
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ACR Meeting Abstracts - https://acrabstracts.org/abstract/performance-of-patient-reported-outcomes-measurement-information-systems-promis-promis-29-and-promis-self-efficacy-in-systemic-sclerosis-ssc/