Abstracts Archive - Page 996 of 2425 - ACR Meeting Abstracts

Abstract Number: 625 • 2019 ACR/ARP Annual Meeting
Associations of Work-Related Abilities with Disability in Ankylosing Spondylitis
Kanika Monga¹, MinJae Lee ², Michael Ward ³, Michael Weisman ⁴, Lianne Gensler ⁵, Mariko Ishimori ⁶, Amirali Tahanan ², Mohammad Rahbar ², Matthew Brown ⁷, Logan Oliver ¹, Soudabeh Daliri ¹, John Reveille ⁸ and Mark Hwang ², ¹University of Houston-McGovern Medical School, HOUSTON, TX, ²University of Texas-McGovern Medical School, Houston, TX, ³NIAMS, Bethesda, MD, ⁴David Geffen School of Medicine at UCLA, Los Angeles, CA, ⁵University San Francisco California, San Francisco, CA, ⁶Cedars-Sinai Medical Center, Los Angeles, CA, ⁷Queensland University of Technology, Queensland, Australia, ⁸University of Texas McGovern Medical School, Houston
Background/Purpose: Withdrawal from the workforce is 3.1 times higher in patients with Ankylosing Spondylitis (AS) compared to the general population [Boonen A, et al. 2001]. Functional…
Abstract Number: 626 • 2019 ACR/ARP Annual Meeting
Are There Really Differences Between Non-radiographic and Radiographic Axial Spondyloarthritis? Data from the Spanish Atlas
Marco Garrido-Cumbrera¹, Jordi Gratacós ², Eduardo Collantes ³, Pedro Zarco ⁴, Carlos Sastre ⁵, Sergio Sanz-Gómez ⁶ and Victoria Navarro-Compán ⁷, ¹Health & Territory Research, Universidad de Sevilla, Seville, Spain, Sevilla, ²Hospital Universitari Parc Taulí, Sabadell, I3PT, UAB, Spain, Sabadell, Spain, ³Reina Sofia University Hospital, Spain. Maimonides Biomedical Research Institute of Cordoba (IMIBIC), University of Cordoba, Cordova, Spain, Cordova, Spain, ⁴Hospital Universitario Fundación Alcorcón, Madrid, Spain, Madrid, Spain, ⁵Novartis Spain, Barcelona, Spain, Barcelona, Spain, ⁶Health & Territory Research (HTR), Universidad de Sevilla, Seville, Spain, Seville, Spain, ⁷University Hospital La Paz, IdiPaz, Madrid, Spain
Background/Purpose: Most research studies support the fact that both, radiographic and non-radiographic axial spondyloarthritis (r-axSpA and nr-axSpA), share similar clinical characteristics and equivalent burden of…
Abstract Number: 627 • 2019 ACR/ARP Annual Meeting
Metabolomics Screening in Axial Spondyloarthritis: Identifying Potential Biomarkers
Andrew Stahly¹, Emilie Regner ², Adam Lefferts ³, Benjamin Brown ⁴, Angelo D'Alessandro ⁴ and Kristine Kuhn ³, ¹University of Colorado, Aurora, CO, ²University of Colorado, Anschutz Medical Campus, Denver, CO, ³University of Colorado, Anschutz Medical Campus, Aurora, CO, ⁴University of Colorado Anschutz Medical Campus, Aurora, CO
Background/Purpose: Early intervention in axial spondyloarthritis (axSpA) may prevent pathogenic changes such as bone remodeling and spinal fusion. Unfortunately, early intervention is difficult, as there…
Abstract Number: 628 • 2019 ACR/ARP Annual Meeting
Pain Perception and Opiate Use Among Patients with Inflammatory Arthritis
Alexis Ogdie¹, Sofia Pedro ² and Kaleb Michaud ³, ¹Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, ²Forward, The National Databank for Rheumatic Diseases, Wichita, KS, ³FORWARD, The National Databank for Rheumatic Diseases and University of Nebraska Medical Center, Wichita, KS
Background/Purpose: Pain is the most common symptom among patients with inflammatory arthritis (IA) and residual pain is common in patients IA despite appropriate treatment. Opiate…
Abstract Number: 629 • 2019 ACR/ARP Annual Meeting
Gender Differences in Comorbidities and Treatment Utilization Among Ankylosing Spondylitis Patients Initiating a Biologic in a Real-World Setting
Anna Sheahan¹, Maya Balamane ¹, Edward Lee ² and Robert Suruki ¹, ¹UCB Pharma, Raleigh, NC, ²UCB Pharma, Smyrna, GA
Background/Purpose: To identify opportunities to optimize treatment of AS, an understanding of the treatment approaches and patient characteristics is necessary. This study describes comorbidities, comedications,…
Abstract Number: 630 • 2019 ACR/ARP Annual Meeting
Assessing the Humanistic and Economic Burden of Enthesitis Among Patients with Peripheral and Axial Spondyloarthritis: Results from a Multi-National Real World Survey Database
Vibeke Strand ¹, Atul Deodhar ², Philip G Conaghan ³, Isabelle Gilloteau ⁴, Olivia Massey ⁵, Haijun Tian ⁶, Aurore Yocolly ⁷, Nicola Booth⁵ and Rieke Alten ⁸, ¹Division of Immunology/Rheumatology, Stanford University, Stanford, CA, ²Oregon Health & Science University, Portland, OR, ³Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds & NIHR Leeds Biomedical Research Centre, Leeds, United Kingdom, ⁴Novartis Pharma AG, Basel, Switzerland, ⁵Adelphi Real World, Bollington, United Kingdom, ⁶Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁷Novartis Product Lifecycle Services –NBS, Novartis Global Service Center, Dublin, Ireland, ⁸Schlosspark-Klinik University Medicine, Berlin, Germany
Background/Purpose: Enthesitis is a major source of pain, functional impairment, and reduced health-related quality of life (HRQoL) in spondyloarthritis (SpA) patients; however, limited information is…
Abstract Number: 631 • 2019 ACR/ARP Annual Meeting
Recognition of Inflammatory Back Pain by US Healthcare Providers and Barriers to Specialist Referral
Marina Magrey¹, Esther Yi ², Daniel Wolin ³, Mark Price ³, Costel Chirila ³, Eric Davenport ³ and Yujin Park ⁴, ¹Division of Rheumatology, The MetroHealth System and School of Medicine, Case Western Reserve University, Cleveland, OH, ²Novartis Pharmaceuticals Corporation, East Hanover, NJ, ³RTI Health Solutions, Research Triangle Park, ⁴Novartis Pharmaceuticals Corporation, East Hanover
Background/Purpose: Early diagnosis of axial spondyloarthritis (axSpA) in the United States remains challenging due to the high prevalence and nonspecific presentation of chronic back pain…
Abstract Number: 632 • 2019 ACR/ARP Annual Meeting
An Observational Analysis of the Co-existence of Brugada Syndrome in Patients with Spondyloarthritis; A Potentially Important Link
Kunal Lall ¹, Robbie Ramsden ², Elijah R. Behr ³ and Virinderjit Sandhu², ¹St.George's University Medical School, London, United Kingdom, ²Department of Rheumatology, St.George's Hospital NHS Foundation Trust, London, United Kingdom, ³Department of Cardiology, St.George's Hospital NHS Foundation Trust, London, United Kingdom
Background/Purpose: Cardiac involvement in Spondyloarthritis (SpA) has been recognised as an important determinant of increased comorbidity and mortality due to atherosclerosis, aortitis, aortic regurgitation and…
Abstract Number: 633 • 2019 ACR/ARP Annual Meeting
Diagnostic Delay in Spondyloarthritis
Santiago Scarafia¹, Maria Paula Girard Bosch ², Mariana Benegas ³, Vanesa Cosentino ⁴, Josefina Marin ⁵, Vanesa Duarte ⁶, Juan Bande ⁷, Maria Julieta Gamba ⁸, Fernando Sommerfleck ⁹, Paula Gonzalez ⁸, Diego Vila ¹⁰, Marina Oliver ¹¹, Maria Mercedes Piovesan ¹², Rodrigo Aguila ¹³, Velozo Edson Javier ¹⁴, Eduardo Kerzberg ¹⁵, Maria Janina Tapia Moreira ¹⁶, Micaela Cosatti ¹⁷, Carla Airoldi ¹⁸, Mercedes Garcia ¹⁹ and Maria Victoria Martire ²⁰, ¹Hospital Municipal "San Cayetano", Buenos Aires, Buenos Aires, Argentina, ²Instituto Médico Platense, La Plata, ³Sanatorio Mendez, Buenos Aires, ⁴Federación de Asociaciones de Trabajadores de la Sanidad Argentina Buenos Aires, Buenos Aires, Argentina, ⁵Hospital Italiano de Buenos Aires, buenos aires, Ciudad Autonoma de Buenos Aires, Argentina, ⁶Clínica Monte Grande, Monte Grande, Buenos Aires, Argentina, ⁷Hospital General de Agudos Dr. E. Tornú, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina, ⁸Hospital Nacional Posadas, Buenos Aires, Buenos Aires, Argentina, ⁹Sanatorio Mendez, Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, ¹⁰Centro Médico Ginecológico Zárate, Zárate, Buenos Aires, Argentina, ¹¹Hospital Privado de Comunidad de Mar del Plata, Mar del Plata, Buenos Aires, Argentina, ¹²Sanatorio Finochietto, Buenos AIres, Ciudad Autonoma de Buenos Aires, Argentina, ¹³HIZGA "San Martin", La Plata, Buenos Aires, Argentina, ¹⁴Sanatorio Adventista del Plata, Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, ¹⁵Hospital Ramos Mejia, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina, ¹⁶Hospital Ramos Mejia, Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, ¹⁷CEMIC, Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, ¹⁸Hospital Provincial de Rosario, Rosario, Santa Fe, Argentina, ¹⁹Hospital San Martín, La Plata, Argentina, ²⁰Hospital San Martín. Instituto Médico Platense, La Plata
Background/Purpose: Spondyloarthritis (Spa) is an heterogeneous group of diseases. Diagnostic delay contributes to poor patient outcome. Prompt diagnosis of Spa is the first step towards…
Abstract Number: 634 • 2019 ACR/ARP Annual Meeting
Targeted 1H NMR Based Metabolomics Analysis Revealed Significantly Higher Synovial Phe/Tyr Ratio in Reactive Arthritis and Undifferentiated Spondyloarthropathy
Hafis Muhammed¹, Dinesh Kumar ², Durgesh Dubey ², Sandeep Kumar ³, Smriti Chaurasia ³, Anupam Guleria ², Sanjukta Majumder ³, Rajeev Singh ³, Vikas Agarwal ¹ and Ramnath Misra ⁴, ¹SGPGI, Lucknow, Uttar Pradesh, India, ²Centre for Biomedical Research, Sanjay Gandhi Post Graduate Institute of Medical Science, Lucknow, Uttar Pradesh, India, ³Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Post Graduate Institute of Medical Science, Lucknow, Uttar Pradesh, India, ⁴Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Lucknow, Uttar Pradesh, India
Background/Purpose: Elevated phenylalanine-to-tyrosine ratio (Phe/Tyr) is a marker of oxidative stress. We hypothesized that the synovial Phe/Tyr in reactive arthritis is higher than Rheumatoid arthritis(RA)…
Abstract Number: 635 • 2019 ACR/ARP Annual Meeting
Association Between Radiographic Progression and Cardiovascular Risk in Spondyloarthritis: Data from CoSpaR REGISTRY
María Lourdes Ladehesa-Pineda¹, Maria Carmen Castro ², Ignacio Gomez-Garcia ², Pedro Seguí-Azpilcueta ³, María del carmen ábalos-Aguilera ⁴, Rocío Segura-Ruiz ⁵, Rafaela Ortega ², Laura Bautista-Aguilar ⁶, Inmaculada Aranda-Varela ⁷, Clementina López-Medina ⁸, Juan Luis Garrido-Castro ⁹, Chary Lopez-Pedrera ², Alejandro Escudero-Contreras ⁷, Eduardo Collantes-Estévez ⁷ and Yolanda Jiménez-Gómez ⁴, ¹Universitary Hospital Reina Sofia of Cordoba/University of Cordoba/IMIBIC, Córdoba, Spain, ²IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Spain, ³Universitary Hospital Reina Sofía of Córdoba, Córdoba, Spain, ⁴IMIBIC, Córdoba, Spain, ⁵Reina Sofia University Hospital/IMIBIC, Córdoba, Spain, ⁶[email protected], Córdoba, Spain, ⁷Universitary Hospital Reina Sofía of Córdoba/University of Córdoba/IMIBIC, Córdoba, Spain, ⁸Cochin Hospital, Rheumatology Department, Paris, France, ⁹University of Córdoba, Córdoba, Spain
Background/Purpose: Our objectives are:To analyze the prevalence of comorbidities related to CV risk in a register of patients with spondyloarthritis (CoSpaR).To evaluate if there is…
Abstract Number: 636 • 2019 ACR/ARP Annual Meeting
Validation and Transcultural Adaptation of the Spanish Version of Brief Index of Lupus Damage (BILD) Questionnaire
María de la Torre¹, María Mercedes Croce ², Analía Alvarez ³ and Cecilia Pisoni ¹, ¹Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno (CEMIC), Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina, ²Hospital General de Agudos "José M. Penna", Buenos Aires, Argentina, ³Hospital General de Agudos José M. Penna, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina
Background/Purpose: Patients with systemic lupus erythematosus (SLE) develop irreversible organ damage as a consequence of disease activity, chronic inflammation, comorbidities and side effects of medications.…
Abstract Number: 637 • 2019 ACR/ARP Annual Meeting
How Often Should SLE Patients Be Tested for Lupus Anticoagulant?
Laurence Magder¹ and Michelle Petri ², ¹University of Maryland School of Medicine, Baltimore, MD, ²Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: SLE patients with persistent lupus anticoagulant (LAC) have been observed to be at significantly higher risk of thrombosis. A common clinical definition of persistent…
Abstract Number: 638 • 2019 ACR/ARP Annual Meeting
Longitudinal Trends for Estimated Glomerular Filtration Rate and Predictors of Change in Patients with Systemic Lupus Erythematosus
Terry Cheuk Fung Yip ¹, Michelle Petri ² and Laurence Magder³, ¹Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong, ²Johns Hopkins University School of Medicine, Baltimore, MD, ³University of Maryland School of Medicine, Baltimore, MD
Background/Purpose: To characterize the longitudinal trajectory of estimated glomerular filtration rate (eGFR) in patients with systemic lupus erythematosus (SLE) and identify predictors of change in…
Abstract Number: 639 • 2019 ACR/ARP Annual Meeting
African-American Risk of Proteinuria After SLE Diagnosis Increases Throughout Thirty Years of Followup
Michelle Petri¹ and Jessica Li ¹, ¹Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: African-Americans lupus nephritis is more common than in Caucasians, more severe and more likely to lead to end stage renal disease. We asked whether…

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