Abstracts Archive - Page 995 of 2425 - ACR Meeting Abstracts

Abstract Number: 610 • 2019 ACR/ARP Annual Meeting
Ankylosing Spondylitis-associated Killer Immunoglobin-like Receptors Are Strongly Expressed on γδ T Cells
Micah Lefton¹, Nihaarika Sharma ¹ and Joerg Ermann ², ¹Brigham and Women's Hospital, Boston, MA, ²Brigham and Women's Hospital, Boston
Background/Purpose: The mechanism underlying the association between ankylosing spondylitis (AS) and HLA-B27 is still unknown. One of the hypotheses involves the interaction of HLA-B27 homodimers…
Abstract Number: 611 • 2019 ACR/ARP Annual Meeting
Retina of Ankylosing Spondylitis Patients Shows Early Signs of Atherosclerotic Disease in Comparison with Healthy Controls
Rianne van Bentum¹, Milad Baniaamam ², Buket Kinaci-Tas ³, Aleid van de Kreeke ⁴, Merve Kocyigit ¹, Pieter Jelle Visser ⁵, Erik Serné ⁶, Frank Verbraak ⁷, Mike Nurmohamed ⁸ and Irene van der Horst-Bruinsma ¹, ¹Amsterdam Rheumatology and immunology Center, Rheumatology, Amsterdam University Medical Center location VUmc, Amsterdam, Amsterdam, Netherlands, ²Amsterdam Rheumatology and immunology Center, Rheumatology, Reade, Amsterdam|Amsterdam Rheumatology and immunology Center, Rheumatology, Amsterdam University Medical Center location VUmc, Amsterdam, Amsterdam, Netherlands, ³Opthalmology dpt., Amsterdam University Medical Center, location AMC, Amsterdam, Amsterdam, Netherlands, ⁴Ophthalmology dpt., Amsterdam University Medical Center, location VUmc, Amsterdam, Amsterdam, Netherlands, ⁵Dpt. of Clinical Chemistry, Amsterdam University Medical Center, Amsterdam, Amsterdam, Netherlands, ⁶Dpt. Internal Medicine, Amsterdam University Medical Center, location VUmc, Amsterdam, Amsterdam, Netherlands, ⁷Ophthalmology dpt., Amsterdam University Medical Center, Amsterdam, Amsterdam, Netherlands, ⁸Amsterdam Rheumatology and immunology Center location Reade and Amsterdam UMC location VU medical center, Amsterdam, Netherlands
Background/Purpose: Chronic systemic inflammation in patients with ankylosing spondylitis (AS) contributes to the development of cardiovascular disease (CVD). Early recognition of microvascular changes could improve…
Abstract Number: 612 • 2019 ACR/ARP Annual Meeting
Objective Ankylosing Spondylitis Physical Performance Index (ASPI) Is Highly Reliable and Feasible in Chilean Patients
Rianne van Bentum¹, Sebastian Ibáñez Vodnizza ², Francisca Valenzuela Aldridge ², Maria Paz Poblete ³, Salima van weely ⁴, Marieke ter Wee ¹, Omar Valenzuela ⁵ and Irene van der Horst-Bruinsma ¹, ¹Amsterdam Rheumatology and immunology Center, Rheumatology, Amsterdam University Medical Center location VUmc, Amsterdam, Amsterdam, Netherlands, ²Rheumatology dpt., Clínica Alemana - UDD Medicine faculty, Santiago, Chile, ³Rheumatology dpt., Facultad de Medicina Clinica Alemana - UDD, Santiago, Region Metropolitana, Chile, ⁴Orthopedics, Rehabilitation and Physical Therapy dpt., Leiden University Medical Center, Leiden, Netherlands, ⁵Facultad de Medicina Clinica Alemana -UDD, Santiago, Region Metropolitana, Chile
Background/Purpose: In axial spondyloarthritis (axSpA), preservation of physical functioning is an important treatment goal and is usually assessed with the patient-reported BASFI questionnaire. The Ankylosing…
Abstract Number: 613 • 2019 ACR/ARP Annual Meeting
Can Fecal Calprotectin Predict Future Development of Inflammatory Bowel Disease in Axial Spondyloarthritis Patients? – TReasure Real-Life Preliminary Data
Gozde Kubra Yardımcı ¹, Ozan Cemal içaçan ², Gokhan Kabadayi ³, Bayram Farisoğulları ¹, Cemal Bes ⁴, Servet Akar ⁵ and Umut Kalyoncu⁶, ¹Hacettepe University Vasculitis Centre, Ankara, Turkey, Ankara, Turkey, ²University of Health Sciences, Bakırköy Sadi Konuk Research and Training Hospital, Rheumatology, İstanbul, ³Izmir Katip Celebi University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, İzmir, Turkey, ⁴University of Medical Sciences, İstanbul, Turkey, ⁵Izmir Katip Celebi University, Faculty of Medicine, Division of Rheumatology, İzmir, Turkey, ⁶Hacettepe University Department of Rheumatology, Ankara, Turkey
Background/Purpose: Inflammatory bowel disease (IBD) is frequently seen in patients with axial spondyloarthritis (axSpA). This study aimed to investigate whether fecal calprotectin levels could predict…
Abstract Number: 614 • 2019 ACR/ARP Annual Meeting
Tapering of Tumor Necrosis Factor Inhibitor and Healthcare Cost Differences in Patients with Ankylosing Spondylitis: A Retrospective Analysis of Korean National Health Insurance Data
Bon San Koo¹, Yu-Cheol Lim ², Min-Young Lee ³, Ja-Young Jeon ⁴, Hyun-Jeong Yoo ⁵, In-Sun Oh ², Ju-Young Shin ² and Tae-Hwan Kim ⁶, ¹Department of Internal Medicine, Inje University Seoul Paik Hospital, Inje University College of Medicine, Seoul, Republic of Korea, ²School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea, ³VIAplus, Siheung, Republic of Korea, ⁴Pfizer Inc, Seoul, Republic of Korea, ⁵Pfizer Korea, Seoul, Republic of Korea, ⁶Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea
Background/Purpose: Tapering of tumor necrosis factor (TNF) inhibitors may be considered in patients with ankylosing spondylitis (AS) with low disease activity. However, there is still…
Abstract Number: 615 • 2019 ACR/ARP Annual Meeting
Effects of NSAIDs and TNF Inhibitors on Cardiovascular Events in Ankylosing Spondylitis: A Systematic Review and Meta-Analysis
Paras Karmacharya¹, Ravi Shahukhal ², Cynthia Crowson ³, M.Hassan Murad ⁴, Pragya shrestha ⁵, Delamo Bekele ⁶, Kerry Wright ⁴, John Davis ⁴ and Maureen Dubreuil ⁷, ¹Reading Hospital, Mayo Clinic, Rochester, ²Lakes Regional General Hospital, Laconia, NH, ³Mayo Clinic Rochester, Rochester, ⁴Mayo Clinic, Rochester, MN, ⁵Mayo Clinic. Rochester, MN, Rochester, MN, ⁶Mayo Clinic Rochester, Rochester, MN, ⁷Boston University School of Medicine, Boston, MA
Background/Purpose: Most studies show a significantly higher risk of myocardial infarction [MI] (odds ratio [OR] = 1.60) and stroke (OR = 1.50) in ankylosing spondylitis (AS)…
Abstract Number: 616 • 2019 ACR/ARP Annual Meeting
Association of Clinical and Radiographic Phenotype of Axial Spondyloarthritis and Skin Psoriasis: Results from the German Spondyloarthritis Inception Cohort
Mikhail Protopopov¹, Fabian Proft ², Joachim Sieper ², Hildrun Haibel ², Martin Rudwaleit ³ and Denis Poddubnyy ⁴, ¹Charité Universitätsmedizin Berlin, Germany, Berlin, Berlin, Germany, ²Charité Universitätsmedizin Berlin, Germany, Berlin, Germany, ³Klinikum Bielefeld, Charité Berlin, Gent University, Bielefeld, Germany, ⁴Charité - Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany
Background/Purpose: Psoriasis is a common feature of axial spondyloarthritis (axSpA) occuring in approximately 10% of patients with axSpA. It has been presumed that such an…
Abstract Number: 617 • 2019 ACR/ARP Annual Meeting
Peripheral Involvement Is Associated with Less Radiographic Spinal Progression in Patients with Early Axial Spondyloarthritis: Results from the German Spondyloarthritis Inception Cohort
Murat Torgutalp ¹, Mikhail Protopopov², Fabian Proft ³, Joachim Sieper ³, Hildrun Haibel ³, Martin Rudwaleit ⁴ and Denis Poddubnyy ⁵, ¹Charité Universitätsmedizin Berlin, Germany and Ankara University Faculty of Medicine, Ankara, Turkey., Berlin, Germany, ²Charité Universitätsmedizin Berlin, Germany, Berlin, Berlin, Germany, ³Charité Universitätsmedizin Berlin, Germany, Berlin, Germany, ⁴Klinikum Bielefeld, Charité Berlin, Gent University, Bielefeld, Germany, ⁵Charité - Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany
Background/Purpose: Peripheral involvement (PI), such as arthritis, enthesitis, and dactylitis, is common in patients with axial spondyloarthritis (axSpA); data showing the influence of PI on…
Abstract Number: 618 • 2019 ACR/ARP Annual Meeting
Factors Associated with Complete Spinal Fusion in Patients with Ankylosing Spondylitis
Yasmin Maldonado¹, Michael Weisman ², Lianne Gensler ³, Michael Ward ⁴, Matthew Brown ⁵, MinJae Lee ⁶, Mark Hwang ⁶, Mariko Ishimori ⁷, Amirali Tahanan ⁶, Tom Learch ⁷, Mohammad Rahbar ⁶ and John Reveille ⁸, ¹The University of Texas-McGovern Medical School, Houston, TX, ²David Geffen School of Medicine at UCLA, Los Angeles, CA, ³University San Francisco California, San Francisco, CA, ⁴NIAMS, Bethesda, MD, ⁵Queensland University of Technology, Queensland, Australia, ⁶University of Texas-McGovern Medical School, Houston, TX, ⁷Cedars-Sinai Medical Center, Los Angeles, CA, ⁸University of Texas McGovern Medical School, Houston
Background/Purpose: Most patients with ankylosing spondylitis (AS) do not develop complete spinal fusion. The purpose of this study was to compare patients with complete spinal…
Abstract Number: 619 • 2019 ACR/ARP Annual Meeting
Relation of Therapies for Ankylosing Spondylitis to Risk of Total Hip and Knee Arthroplasty
Rachael Stovall¹, Christine Peloquin ², David Felson ³, Tuhina Neogi ² and Maureen Dubreuil ⁴, ¹Boston Medical Center, Boston, MA, ²Boston University School of Medicine, Boston, MA, ³Boston University School of Medicine, Department of Rheumatology, Boston, ⁴Boston University School of Medicine, Boston
Background/Purpose: Ankylosing spondylitis (AS) is an inflammatory arthritis that predominantly affects the axial skeleton, but commonly affects peripheral joints as well. Peripheral joint involvement often…
Abstract Number: 620 • 2019 ACR/ARP Annual Meeting
Arterial Elasticity by 2 Dimensional Circumferential Strain and Beta Stiffness Index in Patients with Ankylosing Spondylitis
Helena DElia¹, Lucy Law ¹, Karin Bengtsson ², Mats Geijer ³, Stefan Soderberg ⁴ and Per Lindqvist ⁵, ¹Department of Public Health and Clinical Medicine, Rheumatology, Umeå, Sweden, ²Department of Inflammation and Rheumatology Research, Göteborg, Sweden, ³Department of Radiology, Institute of Clinical Sciences, Göteborg, Sweden, ⁴Department of Public Health and Clinical Medicine, Medicine,, Umeå, Sweden, ⁵Department of Surgical and Perioperative Sciences, Clinical Physiology, Umeå, Sweden
Background/Purpose: Ankylosing spondylitis (AS) is associated with elevated risk of cardiovascular disease (CVD) and increased mortality. Arterial stiffness is associated with atherosclerosis and CV events.…
Abstract Number: 621 • 2019 ACR/ARP Annual Meeting
The Use of Microbial Flow Cytometry to Analyze the Intestinal and Oral Microbiota
Patrick Stauffer¹, Mark Klick ¹, Tammy Martin ¹, James T. Rosenbaum ² and Mark Asquith ¹, ¹Oregon Health and Science University, Portland, OR, ²Devers Eye Institute and Oregon Health & Science University, Portland, OR
Background/Purpose: The role of the microbiome in the pathogenesis of autoimmune disorders such as axial spondyloarthritis (SpA) has been well-established through means of describing gross…
Abstract Number: 622 • 2019 ACR/ARP Annual Meeting
Ten-year Atherosclerotic Cardiovascular Disease Risk Scores in Axial Spondyloarthritis versus the General Population: A Cross-sectional Study
Jean Liew¹, John Reveille ², Henna Sawhney ³, Maria Castillo ³, Benjamin Naovarat ⁴, Susan Heckbert ¹ and Lianne Gensler ⁵, ¹University of Washington, Seattle, WA, ²University of Texas McGovern Medical School, Houston, ³University of California in San Francisco, San Francisco, CA, ⁴University of Texas-McGovern Medical School, Houston, TX, ⁵University San Francisco California, San Francisco, CA
Background/Purpose: Cardiovascular morbidity and mortality are increased in axial spondyloarthritis (axSpA). The 2013 American College of Cardiology/American Heart Association (ACC/AHA) guidelines recommend high intensity statin…
Abstract Number: 623 • 2019 ACR/ARP Annual Meeting
Evaluation of the Early Cervical Structural Changes in Patients with Non-Radiographic Axial Spondyloarthropathy
Melike Cengiz ¹, Şebnem Ataman², Ayşe Peyman Yalçın ³, Ismihan Sunar ³ and Gürkan Yılmaz ³, ¹Ankara Unversity School of Medicine, Physical Medicine and Rehabilitation Department, Ankara, Ankara, Turkey, ²Ankara University School of Medicine, Physical Medicine and Rehabilitation, Rheumatology Department, Ankara, Ankara, Turkey, ³Ankara Unversity School of Medicine, Physical Medicine and Rehabilitation, Rheumatology Department, Ankara, Turkey
Background/Purpose: The aim of this double-blind, controlled, cross-sectional study is to compare the cervical vertebral structural changes of the patients with nr-axSpA, AS and control…
Abstract Number: 624 • 2019 ACR/ARP Annual Meeting
Axial Spondyloarthritis: Knowledge, Screening and Referral Practices Amongst Primary Care Providers
Laura Passalent¹, Christopher Hawke ², Jeff Bloom ², Andrew Bidos ³, Soever Leslie ², Y. Raja Rampersaud ¹, Nigil Haroon ⁴ and Robert Inman ⁵, ¹Toronto Western Hospital, Krembil Research Institute, University of Toronto, Toronto, Canada, ²Toronto Western Hospital, University of Toronto, Toronto, Canada, ³University Health Network, Toronto, Canada, ⁴Toronto Western Hospital, Krembil Research Institute, University of Toronto, Toronto, ON, Canada, ⁵University of Toronto, University Health Network, Toronto, ON, Canada
Background/Purpose: Early recognition is crucial in improving outcomes in patients with axial spondyloarthritis (axSpA). Despite this, there exists long delay between symptom onset and rheumatology…

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