Abstracts Archive - Page 966 of 2425 - ACR Meeting Abstracts

Abstract Number: 175 • 2019 ACR/ARP Annual Meeting
Associations Between Circulating Cytokines and Incident Inflammatory Arthritis in an Anti-citrullinated Protein Antibody Positive Population
Kristen Polinski¹, Elizabeth Bemis ², M. Kristen Demoruelle ³, Marie Feser ⁴, LauraKay Moss ⁵, Jennifer Seifert ⁶, Michael Clare-Salzler ⁷, William Robinson ⁸, V. Michael Holers ⁶, Kevin Deane ⁴ and Jill Norris ⁹, ¹University of Colorado Denver, Aurora, CO, ²University of Colorado Denver, School of Public Health, Aurora, CO USA, Aurora, ³University of Colorado Denver, Division of Rheumatology, Aurora, CO, USA, Aurora, ⁴University of Colorado Denver, Division of Rheumatology, Aurora, CO, USA, Aurora, CO, ⁵University of Colorado Denver, Division of Rheumatology, Aurora, CO USA, Aurora, CO, ⁶University of Colorado Denver, Division of Rheumatology, Aurora, CO, USA, Denver, ⁷Department of Pathology, University of Florida, Gainesville, FL, ⁸Stanford University, Stanford, CA, ⁹Colorado School of Public Health, Aurora
Background/Purpose: Elevated circulating cytokines are present years before the onset of rheumatoid arthritis (RA). We conducted a prospective cohort study in an at-risk population of…
Abstract Number: 176 • 2019 ACR/ARP Annual Meeting
The Epidemiology of Rheumatoid Arthritis in the Czech Republic
Jakub Závada¹, Monika Bezděková ², Michal Uher ³ and Jiří Jarkovský ⁴, ¹Institute of Rheumatology, Prague, Prague, Czech Republic, ²Institute of Health Information and Statistics of the Czech Republic, Praha, Hlavni mesto Praha, Czech Republic, ³Institute of Health Information and Statistics of the Czech Republic, and Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, Czech Republic, Brno, Czech Republic, ⁴Institute of Health Information and Statistics of the Czech Republic, and Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, Czech Republic, Praha, Hlavni mesto Praha, Czech Republic
Background/Purpose: To describe the epidemiology of Rheumatoid Arthritis (RA) in the Czech Republic (CZ)Methods: We used the administrative database of the National Registry of Reimbursed…
Abstract Number: 177 • 2019 ACR/ARP Annual Meeting
Early Retirement Attributed to Rheumatoid Arthritis and Its Predictors in Portugal
Mariana Luís¹, Salomé Garcia ², Francisca Guimarães ³, Manuel António ⁴, Ana Fernandes ⁵, Filipe Araújo ⁶, Rita Cunha ⁷, Maura Couto ⁸, Ana Pinto ⁹, Lígia Silva ¹⁰, Margarida Cruz ¹¹, Jose Pereira da Silva ¹² and Catia Duarte ¹³, ¹Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, ²Centro Hospitalar São João, Porto, Portugal, ³Centro Hospitalar do Alto Minho, Ponte de Lima, Portugal, ⁴Centro Hospitalar Lisboa Norte, Lisboa, Portugal, ⁵Centro Hospitalar do Algarve, Faro, Portugal, ⁶Hospital Ortopédico de Sant’Ana, Lisboa, Portugal, ⁷Centro Hospitalar Baixo Vouga, Aveiro, Portugal, ⁸Centro Hospitalar Tondela-Viseu, Viseu, Portugal, ⁹Unidade Local de Saúde da Guarda, Guarda, Portugal, ¹⁰Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real, Portugal, ¹¹Centro Hospitalar do Oeste, Caldas da Rainha, Portugal, ¹²Centro Hospitalar Universitario de Coimbra, Coimbra, Coimbra, Portugal, ¹³Department of Rheumatology, Centro Hospitalar Universitario de Coimbra, Coimbra, Coimbra, Portugal
Background/Purpose: Work disability is a common consequence of Rheumatoid Arthritis (RA) with economic implications for both the patient and society. Scarce information is available on…
Abstract Number: 178 • 2019 ACR/ARP Annual Meeting
Depression: A Common Comorbidity in Rheumatic Diseases. a Case-Control Study
Dionicio Galarza-Delgado ¹, Jose Azpiri-Lopez ¹, Iris Colunga-Pedraza ¹, Karla Paola Cuellar-Calderon¹, Ileana Cecilia Reynosa-Silva ¹, Marielva Castro-Gonzalez ¹ and Carolina Marlene Martinez-Flores ¹, ¹Universidad Autonoma de Nuevo Leon, Hospital Universitario "Dr Jose Eleuterio Gonzalez", Monterrey, Nuevo Leon, Mexico
Background/Purpose: Depression is a frequent comorbidity in rheumatic diseases (RD) and it is associated with chronic pain and long-term medical treatment in these patients. Furthermore,…
Abstract Number: 179 • 2019 ACR/ARP Annual Meeting
The Burden of Comorbidity in Patients with RA, PSA or SPA in a General Practice Registry
Sofia Pazmino ¹, Veerle Stouten ¹, Patrick Verschueren ², Pavlos Mamouris ¹, Rene Westhovens ³, Kurt De Vlam ², Delphine Bertrand ¹, Kristien Van der Elst ², Bert Vaes ¹ and Diederik De Cock¹, ¹KU Leuven, Leuven, Belgium, ²University Hospital Leuven, Leuven, Belgium, ³University Hospitals, Leuven, Belgium
Background/Purpose: Rheumatoid arthritis (RA), psoriatic arthritis (PSA) and spondyloarthritis (SPA) are the most common inflammatory rheumatic diseases, associated with a high burden of comorbidities and…
Abstract Number: 180 • 2019 ACR/ARP Annual Meeting
Identifying Comorbidities and Seropositivity in Rheumatoid Arthritis Patients Using Single-specialty Electronic Health Record Data
Huifeng Yun¹, Fenglong Xie ², Lang Chen ¹, Shuo Yang ¹ and Jeffrey Curtis ¹, ¹University of Alabama at Birmingham, Birmingham, AL, ²University of Alabama at Birmingham, Birmingham
Background/Purpose: Comorbidities are associated with worse clinical outcomes among patients with rheumatoid arthritis (RA), as does seropositive disease. Rheumatoid factor (RF) and anti-cyclic citrullinated peptide…
Abstract Number: 181 • 2019 ACR/ARP Annual Meeting
Prevalence of Renal Impairment in a US Rheumatoid Arthritis Population
Jon Giles¹, Lee Simon ², Janet Pope ³, Jim Paik ⁴, Michael Grabner ⁵, Amanda Quebe ⁶, Carol Gaich ⁶, Claudia Salinas ⁶ and Jeffrey Curtis ⁷, ¹Division of Rheumatology, Columbia University, New York, NY, ²SDG LLC, Cambridge, ³Western University, London, ON, Canada, ⁴Eli Lilly & Company, Indianapolis, IN, ⁵HealthCore, Inc., Wilmington, DE, ⁶Eli Lilly and Company, Indianapolis, IN, ⁷University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Clinical management of rheumatoid arthritis (RA) must consider patient renal function, particularly for medications that rely on renal clearance and require dose adjustment or…
Abstract Number: 182 • 2019 ACR/ARP Annual Meeting
Comparing the Generalizability of Cardiovascular Risk in Different Rheumatoid Arthritis Cohorts
Fenglong Xie ¹, Cynthia Crowson ², Iris Navarro-Millan ³, Monika Safford ³ and Jeffrey Curtis⁴, ¹University of Alabama at Birmingham, Birmingham, ²Mayo Clinic Rochester, Rochester, ³Weill Cornell Medicine, New York, ⁴University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Cardiovascular (CV) risk estimation across diverse rheumatoid arthritis (RA) cohorts may be challenging given potential heterogeneity in comorbidities and widely varying prevalence of CV…
Abstract Number: 183 • 2019 ACR/ARP Annual Meeting
Exploring Heterogeneity in Rheumatoid Arthritis: Patient Profiling Through Principal Component and Cluster Analysis of the BRASS Registry
Jeffrey Curtis¹, Michael Weinblatt ², Kenneth Saag ¹, Vivian Bykerk ³, Christina Charles-Schoeman ⁴, Stefano Fiore ⁵, Gregory St John ⁶, Toshio Kimura ⁷, Shen Zheng ⁵, Clifton Bingham ⁸, Grace Wright ⁹, Martin Bergman ¹⁰, Kamala Nola ¹¹, Daniel Furst ⁴ and Nancy Shadick ², ¹University of Alabama at Birmingham, Birmingham, AL, ²Brigham and Women's Hospital, Boston, MA, ³Hospital for Special Surgery, New York City, NY, ⁴University of California, Los Angeles, CA, ⁵Sanofi Genzyme, Bridgewater, NJ, ⁶Regeneron Pharmaceuticals, Inc., Tarrytown, NY, ⁷Regeneron Pharmaceuticals, Inc, Tarrytown, NY, ⁸Johns Hopkins University, Baltimore, MD, ⁹Private Practice, New York City, NY, ¹⁰Drexel University College of Medicine, Stockholm, Sweden, ¹¹Lipscomb University College of Pharmacy & Health Sciences, Nashville, TN
Background/Purpose: Data-driven principal component (PC) and cluster analysis has the potential to identify previously unknown patient subgroups within a rheumatoid arthritis (RA) registry to establish…
Abstract Number: 184 • 2019 ACR/ARP Annual Meeting
No Increased Risk of Incidence Diabetes in Patients with Rheumatoid Arthritis Compared to Patients Without RA
Yinzhu Jin ¹, Sarah Chen ², Jun Liu ¹, Rishi Desai ³ and Seoyoung C. Kim¹, ¹Brigham and Women’s Hospital and Harvard Medical School, Boston, ²Brigham and Women's Hospital and Harvard Medical School, Boston, ³Brigham and Women's hospital, Boston
Background/Purpose: Some previously published studies suggest that patients with rheumatoid arthritis (RA) are at an increased risk of developing diabetes mellitus. We examined the risk…
Abstract Number: 185 • 2019 ACR/ARP Annual Meeting
Accrual of Multimorbidity After Incident Rheumatoid Arthritis and Matched Comparators Using a Large Prospective Cohort with 30 Years of Follow-up
Kazuki Yoshida¹, Tzu-Chieh Lin ², Melissa Y Wei ³, Susan Malspeis ¹, Su H. Chu ⁴, Carlos Camargo ⁵, Benjamin A. Raby ¹, Hyon K. Choi ⁵, Sara K. Tedeschi ⁶, Medha Barbhaiya ⁷, Bing Lu ¹, Karen Costenbader ¹, Elizabeth Karlson ¹ and Jeffrey Sparks ¹, ¹Brigham and Women's Hospital, Boston, MA, ²Amgen, Thousand Oaks, CA, ³University of Michigan, Ann Arbor, MI, ⁴Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁵Massachusetts General Hospital, Boston, MA, ⁶Brigham and Women's Hospital, Div. of Rheumatology, Immunology and Allergy, Boston, MA, ⁷Hospital for Special Surgery, Weill Cornell Medicine, New York, NY
Background/Purpose: Rheumatoid arthritis (RA) patients often suffer from multimorbidity, the coexistence of multiple chronic morbidities. However, little is known about how multimorbidity accrues over time…
Abstract Number: 186 • 2019 ACR/ARP Annual Meeting
Asthma, Chronic Obstructive Pulmonary Disease, and Subsequent Risk for Incident Rheumatoid Arthritis Among Women: A Prospective Cohort Study
Julia Ford¹, Xinyi Liu ¹, Su H. Chu ², Bing Lu ¹, Michael Cho ¹, Edwin Silverman ¹, Karen Costenbader ¹, Carlos Camargo ³ and Jeffrey Sparks ¹, ¹Brigham and Women's Hospital, Boston, MA, ²Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ³Massachusetts General Hospital, Boston, MA
Background/Purpose: While RA patients are known to have excess respiratory morbidity and mortality, less is known about the role of chronic respiratory diseases in the…
Abstract Number: 187 • 2019 ACR/ARP Annual Meeting
Epidemiology of JIA-Associated Uveitis: Environmental Factors and Disease Characteristics of a JIA-Associated Uveitis Cohort
Theresa Hennard ¹, Najima Mwase ², Amy Cassedy ³, Joseph McDonald ⁴, Virginia Utz ⁵ and Sheila Angeles-Han⁶, ¹Division of Rheumatology, Cincinnati Children's Hospital and Medical Center, Cincinnati, OH, ²Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, ⁴Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, ⁵Division of Ophthalmology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁶Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cinicinnati
Background/Purpose: JIA-associated uveitis (JIA-U) is the most prevalent extra-articular manifestation of JIA and the most common type of uveitis in children. To date, environmental factors…
Abstract Number: 188 • 2019 ACR/ARP Annual Meeting
The Importance of Diagnosis: Clinical Distinctions Between Adult JIA and RA, and a Characterization of Patients with JIA Reclassified as RA in Adulthood
Kristin Wipfler¹, Sofia Pedro ¹, Yomei Shaw ¹, Rebecca Schumacher ¹, Teresa Simon ², Alyssa Dominique ³, Adam Reinhardt ⁴ and Kaleb Michaud ⁵, ¹FORWARD, The National Databank for Rheumatic Diseases, Wichita, KS, ²Bristol-Myers Squibb*, Princeton, NJ, ³Bristol-Myers Squibb, Princeton, NJ, ⁴Children’s Hospital & Medical Center & University of Nebraska Medical Center, Omaha, NE, ⁵FORWARD, The National Databank for Rheumatic Diseases and University of Nebraska Medical Center, Wichita, KS
Background/Purpose: Upon transitioning from pediatric to adult care, many patients with JIA are labeled as having RA, despite the two diagnoses being distinct in care…
Abstract Number: 189 • 2019 ACR/ARP Annual Meeting
Validation of Claims-based Algorithms to Identify Interstitial Lung Disease in Patients with Rheumatoid Arthritis
Soo-Kyung Cho¹, Tracy J. Doyle ², Hemin Lee ³, Yinzhu Jin ³, Angela Y. Tong ³, Adrian J. Santiago Ortiz ³, Jeffrey Sparks ⁴ and Seoyoung C. Kim ³, ¹Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, ²Brigham and Women's Hospital, Harvard Medical School, Boston, ³Brigham and Women’s Hospital and Harvard Medical School, Boston, ⁴Brigham and Women's Hospital, Boston, MA
Background/Purpose: The prevalence of interstitial lung disease (ILD) among rheumatoid arthritis (RA) patient ranges between 5-10%. ILD leads to high morbidity and mortality in patients…

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