Abstracts Archive - Page 764 of 2607 - ACR Meeting Abstracts

Abstract Number: 0883 • ACR Convergence 2021
Multimorbidity Burden in Systemic Lupus Erythematosus: A Nationwide Study
Ali Duarte-Garcia¹, Herbert Heien¹, Nilay Shah¹ and Cynthia Crowson², ¹Mayo Clinic, Rochester, MN, ²Mayo Clinic, Eyota, MN
Background/Purpose: Patients with systemic lupus erythematosus (SLE) have an increased risk of osteoporosis, end-stage renal disease, cardiovascular disease, and other comorbidities. The presence of multiple…
Abstract Number: 0884 • ACR Convergence 2021
Genetics of Longitudinal Disease Activity in Adults with Systemic Lupus Erythematosus
Linda Hiraki¹, Fangming Liao¹, Dafna Gladman², Ker-Ai Lee³, Zahi Touma⁴, Joan Wither⁵, Richard Cook³ and Murray Urowitz⁶, ¹The Hospital for Sick Children, Toronto, ON, Canada, ²Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada, ³Department of Statistics and Actuarial Sciences, University of Waterloo, Waterloo, ON, Canada, ⁴University of Toronto, Mississauga, ON, Canada, ⁵University Health Network, Toronto, ON, Canada, ⁶Center for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, University of Toronto, Lupus Clinic, Toronto, ON, Canada
Background/Purpose: Genetics and gene expression has been shown to correlate with systemic lupus erythematosus (SLE) disease severity. Our aim was to identify genetic risk loci…
Abstract Number: 0885 • ACR Convergence 2021
SLE Phenotypes Formed from Machine Learning and Their Associations with Cognitive Impairment
Michelle Barraclough¹, Lauren Erdman², Andrea Knight³, Juan Diaz-Martinez⁴, Kathleen Bingham⁵, Jiandong Su⁶, Mahta Kakvan⁶, Maria Tartaglia⁶, Lesley Ruttan⁵, Joan Wither⁶, May Choi⁷, Marvin Fritzler⁸, Dennisse Bonilla⁶, Dorcas Beaton⁹, Ben Parker¹⁰, Robin Green⁶, Patricia Katz¹¹, Ian N. Bruce¹⁰ and Zahi Touma¹², ¹University of Manchester, University Health Network, Toronto, ON, Canada, ²The Hospital of Sick Children, Toronto, ON, Canada, ³Hospital for Sick Children, Toronto, ON, Canada, ⁴UHN, Toronto, ON, Canada, ⁵University of Toronto, University Health Network, Toronto, ON, Canada, ⁶University Health Network, Toronto, ON, Canada, ⁷Brigham and Women's Hospital | University of Calgary, Calgary, AB, Canada, ⁸University of Calgary, Calgary, AB, Canada, ⁹Institute for Work & Health, Toronto, ON, Canada, ¹⁰University of Manchester, Manchester, United Kingdom, ¹¹University of California San Francisco, San Francisco, CA, ¹²University of Toronto, Mississauga, ON, Canada
Background/Purpose: Cognitive impairment (CI) in SLE is a significant problem with limited treatment options. This is in part due to the uncertainty regarding the multifaceted…
Abstract Number: 0886 • ACR Convergence 2021
Determinants of Accessing Social and News Media and Experiencing Negative Impacts During COVID-19 in an International SLE Sample
Francesca Cardwell¹, Susan Elliott², Ricky Chin³, Leigha Rowbottom⁴, Yvan St.Pierre⁵, May Choi³, Murray Urowitz⁶, Guillermo Ruiz-Irastorza⁷, Sasha Bernatsky⁸, Michelle Petri⁹, Susan Manzi¹⁰, Christine Peschken¹¹, Rosalind Ramsey-Goldman¹², Paul R Fortin¹³, Jungmin Shin¹⁴, Sang-Cheol Bae¹⁵, Jiacai Cho¹⁶, Anselm Mak¹⁷, John Hanly¹⁸, Anca Askanase¹⁹, Juanita Romero-Diaz²⁰, Romina Nieto²¹, Bernardo A. Pons-Estel²², Ian N. Bruce²³, Daniel Wallace²⁴ and Ann Clarke⁴, ¹University of Waterloo, Burlington, ON, Canada, ²University of Waterloo, Waterloo, ON, Canada, ³Brigham and Women's Hospital | University of Calgary, Calgary, AB, Canada, ⁴University of Calgary, Calgary, AB, Canada, ⁵Research Institute of the McGill University Health Centre, Montréal, QC, Canada, ⁶Center for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, University of Toronto, Lupus Clinic, Toronto, ON, Canada, ⁷Hospital Universitario Cruces, University of the Basque Country, Bizkaia, Spain, ⁸McGill University, Montréal, QC, Canada, ⁹Johns Hopkins University School of Medicine, Baltimore, MD, ¹⁰Allegheny Health Network, Wexford, PA, ¹¹University of Manitoba, Winnipeg, MB, Canada, ¹²Northwestern University, Chicago, IL, ¹³CHU de Quebec - Universite Laval, Québec City, QC, Canada, ¹⁴Hanyang University Hospital, Seoul, Republic of Korea, ¹⁵Hanyang University Medical Center, Seoul, Republic of Korea, ¹⁶National University Health System (NUHS), Singapore, Singapore, ¹⁷National University of Singapore, Singapore, Singapore, ¹⁸Dalhousie University, Halifax, NS, Canada, ¹⁹Columbia University Medical Center, New York, NY, ²⁰Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Ciudad de México, Federal District, Mexico, ²¹Hospital Provincial de Rosario, Rosario, Argentina, ²²Grupo Oroo - Centro Regional de Enfermedades Autoinmunes y Reumticas (GO-CREAR), Rosario, Argentina, ²³University of Manchester, Manchester, United Kingdom, ²⁴Cedars-Sinai, Los Angeles, CA
Background/Purpose: The spread of COVID-19 misinformation through social/news media is a health risk in SLE. We assessed the determinants of SLE patients accessing health information…
Abstract Number: 0887 • ACR Convergence 2021
Association of Mycophenolate and Azathioprine Use with Cognitive Function in SLE
Chrisanna Dobrowolski¹, Jiandong Su², John McGinley¹, Melissa Fazzari¹, Kathleen Bingham³, Nicole Anderson², Dorcas Beaton⁴, Lesley Ruttan³, Joan Wither², Maria Tartaglia², Mahta Kakvan², Dennisse Bonilla², May Choi⁵, Marvin Fritzler⁶, Patricia Katz⁷, Robin Green², Chaim Putterman¹ and Zahi Touma⁸, ¹Albert Einstein College of Medicine, Bronx, NY, ²University Health Network, Toronto, ON, Canada, ³University of Toronto, University Health Network, Toronto, ON, Canada, ⁴Institute for Work & Health, Toronto, ON, Canada, ⁵Brigham and Women's Hospital | University of Calgary, Calgary, AB, Canada, ⁶University of Calgary, Calgary, AB, Canada, ⁷University of California San Francisco, San Francisco, CA, ⁸University of Toronto, Mississauga, ON, Canada
Background/Purpose: Cognitive dysfunction (CD) is a common manifestation of systemic lupus erythematosus (SLE) which can have detrimental consequences for those affected. To date, no treatments…
Abstract Number: 0888 • ACR Convergence 2021
Disease Flares in Lupus Are Concordant with Ruminococcus Blautia Gnavus Blooms Within Unstable Gut Microbiota Communities
Doua Azzouz¹, Ze Chen¹, Zhi Li¹, Jing Deng¹, Peter Izmirly¹, David Fenyo¹, Jill Buyon¹, Alexander Alekseyenko² and Gregg Silverman¹, ¹NYU Grossman School of Medicine, New York, NY, ²Medical University of South Carolina, Charleston, SC
Background/Purpose: Systemic Lupus Erythematosus is the archetypic systemic autoimmune disease in which dysbiosis in the gut microbiome has been postulated to contribute to disease development…
Abstract Number: 0889 • ACR Convergence 2021
Association of Subjective Cognitive Report Using PDQ-20 to a Neuropsychological Battery in a Cohort of SLE Patients
Ambika Gupta¹, Sindhu Johnson², Jiandong Su³, Andrea Knight⁴, Juan Diaz-Martinez⁵, Kathleen Bingham⁶, Mahta Kakvan³, Maria Tartaglia³, Lesley Ruttan⁶, Joan Wither³, May Choi⁷, Marvin Fritzler⁸, Dennisse Bonilla³, Dorcas Beaton⁹, Patricia Katz¹⁰, Robin Green³ and Zahi Touma¹, ¹University of Toronto, Mississauga, ON, Canada, ²University of Toronto, Toronto, ON, Canada, ³University Health Network, Toronto, ON, Canada, ⁴Hospital for Sick Children, Toronto, ON, Canada, ⁵UHN, Toronto, ON, Canada, ⁶University of Toronto, University Health Network, Toronto, ON, Canada, ⁷Brigham and Women's Hospital | University of Calgary, Calgary, AB, Canada, ⁸University of Calgary, Calgary, AB, Canada, ⁹Institute for Work & Health, Toronto, ON, Canada, ¹⁰University of California San Francisco, San Francisco, CA
Background/Purpose: Systemic Lupus Erythematosus (SLE) can lead to a number of neuropsychiatric manifestations including cognitive impairment (CI). Previous meta-analyses have reported the prevalence of CI…
Abstract Number: 0890 • ACR Convergence 2021
Depression Is Associated with Frailty in Systemic Lupus Erythematosus Patients: Multicenter Retrospective Analysis Using Systemic Lupus Erythematosus International Collaborating Clinics-Frailty Index
Kichul Shin¹, In Ah Choi², Eunyoung Lee³, SE RIM CHOI⁴, Jina Yeo⁵, Yun Jong Lee⁶, Su-Jin Yoo⁷, Bong-Jin Hahm⁴, Jee Eun Park⁴, Ju Ho Lee⁸, Yeong-Wook Song⁴ and Ju Yeon Kim⁴, ¹Seoul Metropolitan Government- Seoul National University Boramae Medical Center, Seoul, Republic of Korea, ²Chungbuk National University Hospital, Cheongju, Republic of Korea, ³Uijeongbu Eulji Medical Center, Seoul, South Korea, ⁴Seoul National University Hospital, Seoul, Republic of Korea, ⁵Gil Medical Center, Seoul, South Korea, ⁶Seoul National University Bundang Hospital, Seongnam-si, Republic of Korea, ⁷Chungnam National University Hospital, Daejeon, Republic of Korea, ⁸Seoul National University Bundang Hospital, Yongin Si, Republic of Korea
Background/Purpose: Systemic Lupus Erythematosus International Collaborating Clinics-Frailty Index (SLICC-FI) is a novel health measure in systemic lupus erythematosus (SLE) and was reported to have impact…
Abstract Number: 0891 • ACR Convergence 2021
Quality of Life Assessment in an Indian Inception Cohort (INSPIRE) of SLE Using Lupus QoL Questionnaire
Liza Rajasekhar¹, Dhundra Bhavani¹, Sneha Tota², Vishnupriya Vijayalekshmi³, Ranjan Gupta⁴, Chengappa Kavadichanda⁵, Vineeta Shobha⁶, VirSingh Negi⁷ and Amita Aggarwal², ¹NIMS, Hyderabad, India, ²Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India, ³AIIMS, New delhi, delhi, India, ⁴AIIMS, New delhi, Ne Delhi, India, ⁵JIPMER, Pondicherry, India, ⁶Saint Johns Medical college, Bengaluru, Bengaluru, India, ⁷Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India
Background/Purpose: Lupus quality of life (Lupus QoL) questionnaire is a disease specific patient reported outcome that is available in multiple languages1. Indian SLE inception cohort…
Abstract Number: 0892 • ACR Convergence 2021
Screening for Cognitive Impairment with the Automated Neuropsychological Assessment Metrics in Patients with Systemic Lupus Erythematosus
Ruyi Pan¹, Juan Diaz-Martinez², Jessica Gronsbell¹ and Zahi Touma³, ¹University of Toronto, Toronto, ON, Canada, ²UHN, Toronto, ON, Canada, ³University of Toronto, Mississauga, ON, Canada
Background/Purpose: The American College of Rheumatology Neuropsychological Battery (ACR-NB) is the standard screening test for cognitive impairment (CI) in systemic lupus erythematosus (SLE). While the…
Abstract Number: 0893 • ACR Convergence 2021
Trajectories of Depressive Symptoms in Systemic Lupus Erythematosus over 7 Years
Seerat Chawla¹, Jiandong Su², Zahi Touma³ and Patricia Katz⁴, ¹University of California Los Angeles, Los Angeles, CA, ²University Health Network, Toronto, ON, Canada, ³University of Toronto, Mississauga, ON, Canada, ⁴University of California San Francisco, San Francisco, CA
Background/Purpose: Depression remains one of the most frequently observed psychiatric disorders in patients with SLE with a pooled prevalence of 35.0% (95% CI: 29.9%-40.3%). Nevertheless,…
Abstract Number: 0894 • ACR Convergence 2021
Help-seeking Behaviors and Treatment Preferences for Sleep Problems Among Persons with Lupus
Deborah Da Costa¹, Josée Savard², Elham Rahme¹ and Paul R Fortin³, ¹McGill University, Montréal, QC, Canada, ²Université Laval, Québec City, QC, Canada, ³CHU de Quebec - Universite Laval, Québec City, QC, Canada
Background/Purpose: Sleep disturbances, including difficulty initiating sleep, maintaining sleep, and/or early morning awakenings are prevalent among persons with lupus and have been shown to contribute…
Abstract Number: 0895 • ACR Convergence 2021
Insight into Intraindividual Variability Across Neuropsychological Tests and Its Association with Cognitive Dysfunction in Patients with Systemic Lupus Erythematosus
Jennifer He¹, Juan Diaz-Martinez², Kathleen Bingham³, Jiandong Su⁴, Mahta Kakvan⁴, Maria Tartaglia⁴, Lesley Ruttan³, Dorcas Beaton⁵, Joan Wither⁴, May Choi⁶, Marvin Fritzler⁷, Nicole Anderson⁴, Dennisse Bonilla⁴, Robin Green⁴, Patricia Katz⁸ and Zahi Touma⁹, ¹Western University, London, ON, Canada, ²UHN, Toronto, ON, Canada, ³University of Toronto, University Health Network, Toronto, ON, Canada, ⁴University Health Network, Toronto, ON, Canada, ⁵Institute for Work & Health, Toronto, ON, Canada, ⁶Brigham and Women's Hospital | University of Calgary, Calgary, AB, Canada, ⁷University of Calgary, Calgary, AB, Canada, ⁸University of California San Francisco, San Francisco, CA, ⁹University of Toronto, Mississauga, ON, Canada
Background/Purpose: Dispersion is defined as the variability in an individual’s performance across multiple tasks at a single assessment visit. This measure has been studied in…
Abstract Number: 0896 • ACR Convergence 2021
Systemic Lupus Erythematosus Disease Flares After SARS-CoV-2 Vaccination
Medha Barbhaiya¹, Jonah Levine¹, Caroline Siegel¹, Vivian Bykerk², Deanna Jannat-Khah¹ and Lisa Mandl¹, ¹Hospital for Special Surgery, New York, NY, ²Division of Rheumatology, Hospital for Special Surgery, New York City, NY
Background/Purpose: Vaccination against SARS-CoV-2 is particularly important for patients with systemic lupus erythematosus (SLE), who may be at increased risk of hospitalization for COVID-19. However,…
Abstract Number: 0897 • ACR Convergence 2021
Age-Stratified Trend of Spinal Radiographic Damage Progression in Patients with Ankylosing Spondylitis
Tae-Han Lee¹, Bon San Koo², Bora Nam³, Seunghun Lee⁴, Kyung Bin Joo⁴ and Tae-Hwan Kim³, ¹Keimyung University Dongsan Hospital, Daegu, Republic of Korea, ²Inje University Seoul Paik Hospital, Seoul, Republic of Korea, ³Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, ⁴Hanyang University Hospital, Seoul, Republic of Korea
Background/Purpose: Previous studies investigating the course of spinal structural progression in patients with ankylosing spondylitis (AS) using the modified Stoke Ankylosing Spondylitis Spine Score (mSASSS)…

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