ACR Meeting Abstracts

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  • Abstract Number: 1311 • ACR Convergence 2020

    Identification of Clinical Phenotypes in Patients with Axial Spondyloarthritis, Peripheral Spondyloarthritis and Psoriatic Arthritis According to Peripheral Musculoskeletal Manifestations: A Cluster Analysis in the International ASAS-PerSpA Study

    Clementina Lopez-Medina1, Sylvie Chevret2, Anna Molto1, Joachim Sieper3, Mehmet Tuncay Duruöz4, Uta Kiltz5, Bassel El-Zorkany6, Najia Hajjaj-Hassouni7, Ruben Burgos-Vargas8, Jose Maldonado-Cocco9, Nelly Ziade10, Meghna Gavali11, Victoria Navarro-Compán12, Shue Fen Luo13, Alessandro Biglia14, Tae-Jong Kim15, Mitsumasa Kishimoto16, Fernando Pimentel-Santos17, Jieruo Gu18, Laura Muntean19, Floris van Gaalen20, Pál Géher21, Marina Magrey22, Sebastian Ibanez23, Wilson Bautista-Molano24, Walter Maksymowych25, Pedro M Machado26, Robert Landewé27, Désirée van der Heijde28 and Maxime Dougados29, 1Rheumatology Department, Cochin Hospital, Paris, Paris, France, 2INSERM (U1153): Clinical Epidemiology and Biostatistics, University of Paris, Paris, France, 3Charité Universitätsmedizin Berlin, Berlin, Germany, 4Marmara University School of Medicine, PMR Department, Rheumatology Division, Istanbul, Turkey, 5Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Herne, Germany, 6Cairo University, Cairo, Egypt, 7Health Sciences College, International University of Rabat (UIR), Rabat, Morocco, 8Department of Rheumatology, General Hospital of Mexico, Ciudad de Mexico, Mexico, 9Buenos Aires School of Medicine, Buenos Aires, Argentina, 10Saint-Joseph University, Beirut, Lebanon, Beirut, Lebanon, 11Nizam’s Institute of Medical Sciences, Hyderabad, India, 12Hospital Universitario La Paz IdiPaz, Madrid, Pais Vasco, Spain, 13Chang Gung Memorial Hospital-Linkou, Taoyuan, Taipei, Taiwan (Republic of China), 14Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy, 15Department of Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, Republic of Korea, 16Department Nephrology and Rheumatology, Kyorin University School of Medicine, Tokyo, Japan, 173.CEDOC, NOVA Medical School, Faculdade de Ciências Médicas da Universidade NOVA de Lisboa, Lisboa, Portugal; 7.Hospital Egas Moniz (CHLO) (Rheumatology Department), Lisboa, Portugal, Lisbon, Portugal, 18Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, guangzhou, China (People's Republic), 19Rheumatology Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania, 20Leiden University Medical Center (LUMC), Leiden, Netherlands, 21Semmelweis University, Budapest, Budapest, Hungary, 22Case Western Reserve University School of Medicine, Cleveland, OH, 23Facultad de Medicina Clínica Alemana – Universidad del Desarrollo, Santiago, Region Metropolitana, Chile, 24University Hospital Fundación Santa Fé de Bogotá and Universidad El Bosque, Bogotá, Colombia, 25University of Alberta, Edmonton, AB, Canada, 26University College London, London, United Kingdom, 27Amsterdam University Medical Center & Zuyderland Hospital, Amsterdam, Netherlands, 28Leiden University Medical Center, Leiden, Netherlands, 29Department of Rheumatology, Hopital Cochin, Université de Paris, Paris, France

    Background/Purpose: Patients with a clinical diagnosis of Spondyloarthritis (SpA) and Psoriatic Arthritis (PsA) may have predominant axial or predominant peripheral symptoms. However, a huge clinical…
  • Abstract Number: 1317 • ACR Convergence 2020

    A Large Agreement Between the Pain Points of the ACR 1990 Fibromyalgia Criteria and the MASES Enthesitis Score Is Observed in Patients with Axial Spondylitis, Including in Patients Without Concomitant Fibromyalgia

    Faten Hamitouche1, Clementina Lopez-Medina2, Laure Gossec3, Serge Perrot4, Maxime Dougados5 and Anna Molto6, 1Rheumatology Department, Cochin Hospital, Paris, Ile-de-France, France, 2Rheumatology Department, Cochin Hospital, Paris, Paris, France, 3Sorbonne Université and Hôpital Universitaire Pitié Salpêtrière, Paris, France, 4Paris Descartes University, Paris, Ile-de-France, France, 5Université de Paris, Department of Rheumatology, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Paris, France, 6Rheumatology Department, Cochin Hospital, APHP, Paris, France, Paris, France

    Background/Purpose: Enthesitis is the hallmark lesion in Spondyloarthritis (SpA). The Maastricht Ankylosing Spondylitis Enthesitis score (MASES), which assesses 13 enthesitic sites, is the most widely…
  • Abstract Number: 1316 • ACR Convergence 2020

    Patient Perceptions of Fibromyalgia Symptoms and the Overlap with Axial Spondyloarthritis

    Kelly Gavigan1, William Nowell2, Regan Reynolds1, Laura Stradford1, Jeffrey R Curtis3 and Alexis Ogdie4, 1Global Healthy Living Foundation, Upper Nyack, NY, 2Global Healthy Living Foundation, New York City, NY, 3Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 4University of Pennsylvania, Philadelphia, PA

    Background/Purpose: In clinical practice, it is often challenging to distinguish fibromyalgia syndrome (FMS) from axial spondyloarthritis (axSpA), which includes ankylosing spondylitis and non-radiographic axSpA. Early stages…
  • Abstract Number: 1322 • ACR Convergence 2020

    Prevalence and Associated Factors of Sleep Disorders in Patients with Axial Spondyloarthritis. Results from the European Map of Axial Spondyloarthritis (EMAS)

    Marco Garrido-Cumbrera1, Victoria Navarro-Compán2, Laura Christen3, Christine Bundy4, Raj Mahapatra5, Souzi Makri6, Carlos-Jesus Delgado-Domínguez7, José Correa-Fernández8 and Denis Poddubnyy9, 1Health & Territory Research (HTR), Universidad de Sevilla / Spanish Federation of Spondyloarthritis Associations, Sevilla, Spain, 2Hospital Universitario La Paz IdiPaz, Madrid, Pais Vasco, Spain, 3Novartis Pharma AG, Basel, Switzerland, 4Cardiff University, Cardiff, United Kingdom, 5Axial Spondyloarthritis International Federation, London, United Kingdom, 6Cyprus League Against Rheumatism, Nicosia, Cyprus, 7Health & Territory Research, Seville, Spain, 8Health & Territory Research (HTR), Universidad de Sevilla, Sevilla, Spain, 9Charité – Universitätsmedizin Berlin, Berlin, Germany

    Background/Purpose: Sleep is an essential health aspect that is often impacted in patients with axial spondyloarthritis (axSpA). This analysis aims to assess the prevalence and…
  • Abstract Number: 1324 • ACR Convergence 2020

    Risk Factors for Adverse Pregnancy Outcomes in Women with Spondyloarthritis: An Observational Study from Two European Multidisciplinary Pregnancy Clinics

    Ana Rita Cruz-Machado1, Francesca Crisafulli2, Sofia Barreira3, Patricia Martins4, Maria Chiara Gerardi5, Matteo Filippini2, Micaela Fredi2, Roberto Gorla6, Maria Grazia Lazzaroni2, Cecilia Nalli6, Marco Taglietti2, Andrea Lojacono7, Sonia Zatti8, Monica Centeno9, Cláudia Araújo10, Luísa Pinto10, Franco Franceschini11, Angela Tincani12, Susana Capela1 and Laura Andreoli2, 1Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisboa, Portugal, 2Rheumatology and Clinical Immunology Unit, Spedali Civili and University of Brescia, Brescia, Lombardia, Italy, 3Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon, Portugal, 4Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Universit�rio Lisboa Norte - Hospital de Santa Maria, Set�bal, Portugal, 5Rheumatology and Clinical Immunology Unit, Spedali Civili and University of Brescia, Milano, Italy, 6Rheumatology and Clinical Immunology Unit, Spedali Civili and University of Brescia, Brescia, Italy, 7Obstetrics and Gynaecology, Spedali Civili and University of Brescia, Brescia, Italy, 8Obstetrics and Gynecology Unit, Spedali Civili and University of Brescia, Brescia, Lombardia, Italy, 9Departamento de Obstetrícia, Ginecologia e Medicina da Reprodução, Hospital de Santa Maria, CHULN, Lisbon, Portugal, 10Departamento de Obstetrícia, Ginecologia e Medicina da Reprodução, Hospital de Santa Maria, CHULN, Lisboa, Portugal, 11Rheumatology and Clinical Immunology, Spedali Civili and University of Brescia, Brescia, Italy, 12Rheumatology and Clinical Immunology, Spedali Civili and University of Brescia, Milano, Italy

    Background/Purpose: Women with Spondyloarthritis (SpA) seem at increased risk for adverse pregnancy outcomes (APO), however limited data have been published so far.  The aim of…
  • Abstract Number: 1319 • ACR Convergence 2020

    Disease Activity and Mental Health of as Patients: A Cross-section Study with Self-assessments Based on Smart System of Disease Management (SSDM) Mobile Tools

    Hui Song1, Hua Wei2, Miaojia Zhang3, Lijun Wu4, Zhenbiao Wu5, Aichun Chu6, Bei Wang7, Wenqiang Fan8, Xiaohan Wang9, Xiaoqi Chen10, Henglian Wu11, Wenyu Zhou12, Fei Xiao13, Hui Xiao14, Yuhua Jia13, Bing Wu13 and Jing Lu15, 1Beijing Jishuitan Hospital, Beijing, China (People's Republic), 2Northern Jiangsu People's Hospital, Yangzhou, China (People's Republic), 3Jiangsu Province Hospital, The first affiliated hospital of Nanjing medical university, Nanjing, China (People's Republic), 4People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China (People's Republic), 5The First Affiliated Hospital of The Air Force Medical University, Xi'an, Shanxi, China (People's Republic), 6Remin Hospital of Wuhan University Hubei General Hospital, Wuhan, China (People's Republic), 7Beijing Hospital of Traditional Chinese Medicine, Beijing, China (People's Republic), 8Central Hospital of XinXiang, Xinxiang, China (People's Republic), 9Anyang district hospital, Anyang, Henan, China (People's Republic), 10Zhongnan Hospital of Wuhan University, Wuhan, China (People's Republic), 11Dongguan Donghua Hospital, Dongguan, Guangdong, China (People's Republic), 12Wuhan No. 4 Hospital, Wuhan, China (People's Republic), 13Shanghai Gothic Internet Technology Co., Ltd., Shanghai, China (People's Republic), 14Shanghai Gothic Internet Technology Co., Ltd., Shanghai, Shanghai, China (People's Republic), 15First Affiliated Hospital of China Medical University, Shenyang, China (People's Republic)

    Background/Purpose: WHO survey showed that the prevalence of anxiety and depression in Chinese population and Chinese patients with chronic diseases were between 3.1% - 4.2%…
  • Abstract Number: 1314 • ACR Convergence 2020

    Fatigue in Psoriatic Arthritis (PsA): Prevalence in Patients from the US and Europe, and Impact on Quality of Life and Work Productivity

    Jessica Walsh1, Kaleb Michaud2, Elizabeth Holdsworth3, Steven Peterson4, Nicola Booth3, Sophie Meakin3, Soumya Chakravarty5, James Piercy3 and Alexis Ogdie6, 1University of Utah School of Medicine, George E. Wahlen Veteran Affairs Medical Center, Salt Lake City, UT, 2University of Nebraska Medical Center, Omaha, NE, 3Adelphi Real World, Bollington, United Kingdom, 4Janssen Immunology Global Commercial Strategy Organization, Horsham, PA, 5Janssen Scientific Affairs, LLC, Horsham, PA, USA and Drexel University College of Medicine, Horsham, PA, 6Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Fatigue is an important aspect of PsA for patients.  Understanding the impact of fatigue on patient reported outcomes is important for effective management of…
  • Abstract Number: 1327 • ACR Convergence 2020

    Comorbidity Burden in Patients with Non-Radiographic Axial Spondyloarthritis at Least as High as in Ankylosing Spondylitis

    Jonas Sagard1, Elisabet Lindqvist2, Elisabeth Mogard1, Anna Jöud3, Mats Geijer4, Tor Olofsson1 and Johan K. Wallman1, 1Department of Clinical Sciences Lund, Rheumatology, Lund University, Sweden. Department of Rheumatology, Skåne University Hospital, Lund, Sweden., Lund, Sweden, 2Department of Clinical Sciences Lund, Rheumatology, Lund University, Sweden. Department of Rheumatology, Skåne University Hospital. Lund, Sweden, Lund, Sweden, 3Department of Laboratory Medicine, Division of Occupational and Environmental Medicine, Lund University, Sweden., Lund, Sweden, 4Department of Radiology, Institute of Clinical Sciences, University of Gothenburg, Sahlgrenska Academy, Gothenburg, Sweden. Department of Radiology, Sahlgrenska University Hospital, Gothenburg, Sweden., Gothenburg, Sweden

    Background/Purpose: Few studies have investigated the overall occurrence of comorbidities in patients with non-radiographic axial spondyloarthritis (nr-axSpA) in relation to ankylosing spondylitis (AS). Compared to…
  • Abstract Number: 1330 • ACR Convergence 2020

    Subclinical atherosclertoic disease in ankylosing spondylitis and non-radiographic axial spondyloarthritis. A multicenter study with 806 patients.

    Inigo Gonzalez-Mazon1, Javier Rueda-Gotor2, Ivan Ferraz-Amaro3, Lara Sanchez-Bilbao4, David Martinez-Lopez5, Fernanda Genre6, Natalia Palmou Fontana7, Vanesa Calvo-Río2, Sara Remuzgo-Martínez6, Veronica Pulito-Cueto6, Alfonso Corrales8, Leticia Lera-Gómez6, Virginia Portilla6, Cristina Mata9, Vanesa Hernández-Hernández10, Santos Castañeda11, Esther Francisca Vicente-Rabaneda12, C Fernandez-Carballido13, M Paz Martínez-Vidal14, David Castro-Corredor15, Joaquín Anino-Fernández15, Juan Carlos Quevedo-Abeledo16, Carlos Rodríguez-Lozano17, María Luz García Vivar,18, Eva Galínez-Agirregoikoa18, C. Fernandez-Diaz19, Javier Llorca20, Raquel López-Mejías6, Esther Montes-Perez21, Diana Peiteado22, Chamaida Plasencia23, Alejandro Balsa-Criado24, Nuria Barbarroja25, Lourdes Ladehesa-Pineda26, Rafaela Ortega-Castro27, Eduardo Collantes-Estévez26, Ricardo Blanco28 and Miguel Ángel González-Gay29, 1Hospital Universitario Marques de Valdecilla, Bezana, Spain, 2H.U. Marques de Valdecilla, Santander, Spain, 3Division of Rheumatology. Hospital Universitario de Canarias. Spain., Santa Cruz de Tenerife, Spain, 4Hospital Universitario Marques de Valdecilla, Santander, Spain, 5Hospital Universitario Marques de Valdecilla, Santander (SPAIN), Spain, 6Research group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and in Metabolic bone Diseases of the Musculoskeletal System, IDIVAL, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain, 7UNIVERSITARY HOSPITAL MARQUES VALDECILLA, Santander, Spain, 8Research group on genetic epidemiology and atherosclerosis in systemic diseases and in metabolic bone diseases of the musculoskeletal system, IDIVAL; and Department of Rheumatology, Hospital Universitario Marqués de Valdecilla, Santander, Spain, 9Hospital de Laredo, Santander, Spain, 10Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, 11Princesa University Hospital, Universidad Autónoma, Madrid, Madrid, Spain, 12Hospital Universitario de la Princesa, IIS-Princesa, UAM, Madrid, Madrid, Spain, 13H San Juan, Alicante, Spain, 14Hospital General Universitario de Alicante, Alicante, Spain, 15Hospital General Universitario de Ciudad Real, Ciudad Real, Spain, 16Hospital Dr. Negrín, Las Palmas de Gran Canaria, Spain, 17Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Spain, 18Hospital Universitario Basurto, Bilbao, Spain, 19H. Marqués de Valdecilla, Madrid, Spain, 20School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), Santander, Spain, 21Diagnóstico Médico Cantabria (DMC), Santander, Spain, 22Hospital Universitario La Paz-IdiPaz, Madrid, Spain, 23Rheumatology, La Paz University Hospital-IdiPAZ, madrid, Spain, 24HOSPITAL UNIVERSITARIO LA PAZ, madrid, Spain, 25Rheumatology Department, Reina Sofia University Hospital/ Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, Cordoba, Spain, 26Rheumatology Department, Reina Sofia University Hospital/ Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, Córdoba, Spain, 27Hospital Universitario Reina Sofía, Córdoba, Spain, 28Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain, 29Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain

    Background/Purpose: Cardiovascular (CV) mortality and morbidity is increased in ankylosing spondylitits (AS) as compared to the general population. Carotid plaque, considered as a surrogate marker…
  • Abstract Number: 1331 • ACR Convergence 2020

    Carotid Ultrasound Findings in Psoriatic Arthritis: A Case-control Study

    Dionicio Ángel Galarza-Delgado1, José Ramón Azpiri López2, Iris Jazmín Colunga Pedraza3, Diana Elsa Flores Alvarado4, Octavio Ilizaliturri Guerra4, Paola Fernanda Frausto Lerma3, Itzel Corina Zárate Salinas2, Alejandra Pérez Villar3, Mayra Alejandra Reyes Soto3, Salvador Lugo Pérez2 and Andrea Cecilia Garza Acosta5, 1Rheumatology Service, Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma Nuevo León, Monterrey, Nuevo Leon, Mexico, 2Cardiology Service, Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma Nuevo León, Monterrey, Mexico, 3Rheumatology service, Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma Nuevo León, Monterrey, Mexico, 4Rheumatology Service, Hospital Universitario “Dr. José Eleuterio González, Universidad Autónoma Nuevo León, Monterrey, Nuevo Leon, Mexico, 5Radiology Service, Hospital Universitario “Dr. José Eleuterio González, Universidad Autónoma Nuevo León, Monterrey, Nuevo Leon, Mexico

    Background/Purpose: Patients with psoriatic arthritis (PsA) have an increased risk of cardiovascular disease (CVD). The carotid ultrasound, which measures both carotid intima-media thickness (cIMT) and…
  • Abstract Number: 1326 • ACR Convergence 2020

    Malignancy Risk Among Patients with Ankylosing Spondylitis in the United States: A Population-Based National Study

    Sali Merjanah1, Mohamad Bittar2 and Marina Magrey3, 1Case Western Reserve University, MetroHealth Medical Center, Cleveland, OH, 2The University of Tennessee Health Science Center, Memphis, TN, 3Case Western Reserve University School of Medicine, Cleveland, OH

    Background/Purpose: Increased cancer risk has been reported with Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE), but the correlation is poorly studied in Ankylosing spondylitis…
  • Abstract Number: 1337 • ACR Convergence 2020

    Relationship of the Pro12Ala Polymorphism of the PPARg Gene with Inflammatory Activity, Osteoporosis and Obesity in Patients with Psoriatic Arthritis

    Olga Compán1, Maria Elisa Acosta2, Sonia Pastor2, Guadalupe Manzano Canabal2, Luis Gomez-Lechon Quiros3, Cristina Hidalgo Calleja4, Noelia Cubino2, Ricardo Usategui5, Rogelio Gonzalez Sarmiento5, Olga Martinez Gonzalez6, Ana Isabel Turrión2, Javier Del Pino-Montes2 and Carlos Montilla Morales2, 1Hospital Universitario de Salamanca, ´Salamanca, Spain, 2Hospital Universitario de Salamanca, Salamanca, Spain, 3Complejo Asistencial Universitario de Salamanca, Salamanca, Spain, 4Hospital Universitario Salamanca, Salamanca, Spain, 5Instituto de Investigación Biomédica de Salamanca, Salamanca, Spain, 6Hospital Universitario de Salamanca, Zamora, Spain

    Background/Purpose: In the pathogenesis of psoriatic arthritis (PsA), increased inflammatory cytokines lead to increased RANGO-L activity and stimulation of osteoclasts, leading to osteoporosis. This comorbidity,…
  • Abstract Number: 1334 • ACR Convergence 2020

    Does Interstitial Lung Disease Represent a Real Comorbidity in Spondyloarthritis Patients? Results from an Ultrasound, Monocentric, Pilot Study

    Andrea Delle Sedie1, Emanuele Calabresi1, Ilaria Romagnoli1, Linda Carli2 and Marta Mosca2, 1Rheumatology Unit, University of Pisa, Pisa, Italy, 2Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

    Background/Purpose: Background: Interstitial lung disease (ILD) is a frequent complication in rheumatoid arthritis (RA) where it represents the most common extra-articular involvement (with a prevalence…
  • Abstract Number: 1329 • ACR Convergence 2020

    Subclinical Atherosclerosis Risk in Psoriatic Arthritis: Could It Be Prevented?

    Mai Farouk1, Salwa Moussa1 and Rowaida Abdou1, 1Rhuematology Ain Shams University Hospitals, Cairo, Egypt

    Background/Purpose: Psoriatic arthritis (PsA) is an immune-mediated inflammatory arthritis associated with psoriasis that can cause remarkable joint damage (1). Subclinical cardiovascular disease (CVD) due to…
  • Abstract Number: 1221 • ACR Convergence 2020

    Evaluation of Methotrexate Efficacy and Exploration of Metabolites Associated with Disease Activity in Collagen-induced Arthritis Mouse Model

    Yu Kyoung Cho1 and Ryan Funk1, 1UNIVERSITY OF KANSAS, Kansas City, KS

    Background/Purpose: Methotrexate (MTX) is cornerstone of therapy for rheumatoid arthritis. However, response to MTX is variable and unpredictable among patients. Therefore, there is a critical…
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