Abstracts Archive - Page 673 of 2425 - ACR Meeting Abstracts

Abstract Number: 0682 • ACR Convergence 2020
Role of Inflammatory and Oxidative Stress Pathway Biomarkers in Renal Disease in Gout
Fatima Alduraibi¹, Karina Ricart¹, Rakesh Patel¹, Alexander Szalai¹, Joshua Melnick² and Jasvinder Singh¹, ¹University of Alabama at Birmingham, Birmingham, AL, ²University of Alabama at Birmingham (UAB), Vestavia Hills, AL
Background/Purpose: To understand the role of inflammatory cytokines and oxidative stress biomarkers in the renal disease in people with gout. We hypothesized that higher gout…
Abstract Number: 0681 • ACR Convergence 2020
Gout and Serum Urate Levels Are Associated with Lumbar Spine Monosodium Urate Deposition and Chronic Low Back Pain: A Dual-Energy CT Study
Michael Toprover¹, Michael Mechlin², Anastasia Slobodnick³, Virginia Pike⁴, Cheongeun Oh⁵, Claudine Davis², Theodore Fields⁶, Fabio Becce⁷ and Michael Pillinger⁸, ¹New York University Langone Health, New York, NY, ²NYU Langone Health, New York, NY, ³Stamford Health Medical Group, Stamford, CT, ⁴NYU Langone Health, Brooklyn, NY, ⁵NYU Grossman School of Medicine, New York, ⁶Hospital for Special Surgery, New York, NY, ⁷Lausanne University, Lausanne, Switzerland, ⁸New York University Grossman School of Medicine, New York,, NY
Background/Purpose: Spinal gout is reported as a rare event, presenting as acute back pain, neuropathy, and spinal compression. Diagnosis is commonly based on identification of…
Abstract Number: 0687 • ACR Convergence 2020
Musculoskeletal Manifestations in Patients with CD73 Deficiency
Cornelia Cudrici¹, Kam Newman², Deepak Lakshmipathy¹, Elisa Ferrante¹, Rebecca Huffstutler¹, Katherine Carney¹, Blas Betancourt², Markku Miettinen³, James Katz⁴, Leon Nesti⁵, Han Wen¹, Manfred Boehm⁶ and Alessandra Brofferio¹, ¹National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, ²National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ³National Cancer Institute, National Institutes of Health, Bethesda, MD, ⁴NIH NIAMS, Bethesda, MD, ⁵Clinical and Experimental Orthopaedics, Walter Reed National Military Medical Center, Bethesda, MD, ⁶Center for Molecular Medicine, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
Background/Purpose: Arterial calcification due to deficiency of CD73 (ACDC) is a hereditary autosomal recessive ectopic mineralization syndrome caused by loss-of-function mutations in the 5'-nucleotidase Ecto…
Abstract Number: 0686 • ACR Convergence 2020
Renal Evolution During the First Year of Urate-lowering Therapy According to Sonographic Joint Deposition: Data from the Lille-Alicante Inception Cohort
Irene Calabuig¹, Anne Marty-Ané², Laurène Norberciak³, Jean--Francois Budzik⁴, Agustín Martínez-Sanchis⁵, Mariano Andrés¹ and Tristan Pascart³, ¹Hospital General Universitario de Alicante-ISABIAL and Universidad Miguel Hernández de Elche, Alicante, Spain, ²GHICL, Lille, France, ³GHICL, Lomme, France, ⁴University of Lille, Lille, France, ⁵Hospital General Universitario de Alicante-ISABIAL, Alicante, Spain
Background/Purpose: Gout is associated with chronic kidney disease, but how the kidney function evolves when gout is treated with urate lowering therapy (ULT) is still…
Abstract Number: 0692 • ACR Convergence 2020
Pre-Operative Opioid Usage Increases Length of Stay for Rheumatoid Arthritis Patients Undergoing Total Hip Arthroplasty and Total Knee Arthroplasty
Kyle Morse¹, Nicole Heinz¹, Jeremy Abolade¹, Joshua Wright-Chisem¹, Linda Russell², Meng Zhang³, Serene Mirza¹, Dana Orange⁴, Mark Figgie⁵, Peter Sculco² and Susan Goodman⁵, ¹Hospital for Special Surgery, New York, ²Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, ³Feinstein Institute, Northwell Health, New York, ⁴Rockefeller University, New York, ⁵Hospital for Special Surgery, Weill Cornell Medicine, New York, NY
Background/Purpose: Total Hip (THA) and total knee arthroplasty (TKA) are cost-effective procedures that improve the health-related quality of life for patients with advanced symptomatic joint…
Abstract Number: 0694 • ACR Convergence 2020
Relationships Among Adherence and Patient Outcomes in a Cognitive Behavioral Plus Physical Activity Intervention for Older Adults with Osteoarthritis and Hypertension
Xiaojun Shi¹, Elizabeth Schlenk² and Susan Sereika¹, ¹University of Pittsburgh School of Nursing, Pittsburgh, ²University of Pittsburgh School of Nursing, Pittsburgh, PA
Background/Purpose: Osteoarthritis of the knee (OAK) affects nearly 14 million older adults and more than half are diagnosed with hypertension (HTN). Cognitive behavior therapy (CBT)…
Abstract Number: 0689 • ACR Convergence 2020
The Changing Epidemiology of Inpatient Gout and Associated Mortality: A 17-year National Study
Jasvinder Singh¹ and John Cleveland¹, ¹University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Knowledge gaps exist regarding time-trends for the main causes (Cardiac/renal disease vs. infections) hospitalizations in gout. Therefore, we examined whether specific causes (cardiovascular, renal,…
Abstract Number: 0684 • ACR Convergence 2020
The Shrinking Toe: A Sign of Crystal Dissolution During Urate Lowering Treatment of Severe Gouty Arthropathy
Thomas Bardin¹, Nguyen Dinh Quang², Hieu Le Nghia², Tran Minh Khoi², Hang Korng EA³, Valérie Bousson⁴ and Pascal Richette⁵, ¹Université de Paris, INSERM U1132 and Hôpital Lariboisièe, Paris, France, Paris, France, ²Vien Gut Medical Center, Ho Chi Minh City, Vietnam, ³Universite de Paris, AP-HP, INSERM, paris, France, ⁴Lariboisière Hospital, Paris, France, ⁵Department of Rheumatology, Lariboisière Hospital, Paris, France
Background/Purpose: Serum urate (SU) lowering has been reported to improve gout erosions. We observed that it may also lead to compaction of toe MTP or…
Abstract Number: 0697 • ACR Convergence 2020
Inferior Tendon Structure and Function Seen in Patients with Achilles Tendinopathy and Neovascularization of the Achilles Tendon
Brian Honick¹, Haraldur Sigurdsson¹ and Karin Silbernagel¹, ¹University of Delaware, Newark, DE
Background/Purpose: In prior research, the incidence rate of neovascularization with Achilles tendinopathy ranged between 47-88% of cases. The purpose of this study was to identify…
Abstract Number: 0700 • ACR Convergence 2020
Lipoxin A4 Induces Lipid Class Switching and Inflammation Resolution at the Genomic Level in Human Osteoarthritis
Mandar Dave¹, Abul Islam², Akshat Parekh³, Jay Patel⁴, Arushi Chawla⁵ and Ashok Amin⁶, ¹Department of Rheumatology and Pathology, New York University Hospital for Joint Diseases, New York, ²Department of Genetic Engineering and Biotechnology, University of Dhaka, Dhaka, Bangladesh, ³Rutgers Robert Wood Johnson Medical School, Piscataway, NJ, ⁴Northeast Ohio Medical University, Rootstown, OH, ⁵Gujarat Forensic Science University, Gujarat, India, ⁶Department of Rheumatology and Pathology, New York University Hospital for Joint Diseases, New York, NY
Background/Purpose: Human OA-affected cartilage does not show the cardinal signs of inflammation (redness and swelling with heat and pain—rubor et tumor cum calore et dolor) because…
Abstract Number: 0701 • ACR Convergence 2020
miRNome Sequencing Identifies a Unique Profile of Circulating MicroRNAs in Early Knee Osteoarthritis
S. Amanda Ali¹, Rajiv Gandhi², Pratibha Potla², Sareh Keshavarzi², Osvaldo Espin-Garcia², Konstantin Shestopaloff², Chiara Pastrello³, Dylan Bethune-Waddell², Starlee Lively², Anthony Perruccio⁴, Raj Rampersaud², Christian Veillette², Jason Rockel², Igor Jurisica², Tom Appleton⁵ and Mohit Kapoor⁶, ¹Henry Ford Health System, Detroit, MI, ²Krembil RI, Toronto, Canada, ³University Health Network, Toronto, ON, Canada, ⁴Krembil Research Institute, UHN; University of Toronto, Toronto, ON, Canada, ⁵The University of Western Ontario, LONDON, ON, Canada, ⁶Krembil RI, Toronto, ON, Canada
Background/Purpose: MicroRNAs have been shown to contribute to osteoarthritis (OA) pathophysiology, yet little is known about the circulating miRNome in OA. The circulating miRNome (e.g.…
Abstract Number: 0696 • ACR Convergence 2020
Femoral Cartilage Ultrasound Echo-Intensity Associates with Arthroscopic Cartilage Damage in People Following Anterior Cruciate Ligament Reconstruction
Matthew Harkey¹, Erin Little², Mikaela Thompson³, Ming Zhang⁴, Jeffrey Driban⁴ and Matthew Salzler³, ¹University of Massachusetts, Worcester, MA, ²Tufts Medical Center, Cambridge, MA, ³Tufts Medical Center, Boston, ⁴Tufts Medical Center, Boston, MA
Background/Purpose: Over one-third of people will develop knee osteoarthritis within 10 years of an anterior cruciate ligament (ACL) injury. Ultrasound may be used to monitor…
Abstract Number: 0704 • ACR Convergence 2020
The Murine Ear Wound Cartilage Superhealer Trait, Mediated by the Gut Microbiome, Is Transgenerationally Heritable Following Cecal Transplantation
Christopher Dunn¹, Cassandra Garman², Cassandra Velasco², Vladislav Izda², Jake Martin² and Matlock Jeffries², ¹University of Oklahoma Health Sciences Center, Oklahoma City, ²University of Oklahoma Health Sciences Center, Oklahoma City, OK
Background/Purpose: MRL/MpJ mice are substantially protected from developing post-traumatic osteoarthritis (OA), a trait with strong correlation to the ability to heal ear wounds. We have…
Abstract Number: 0699 • ACR Convergence 2020
Lumbar Spine Stenosis Treatment : Is Surgery Better Than Medical Treatment in Afro-Descendant Populations ?
Fabienne Louis-sidney¹, Serge Arfi¹, Moustapha Drame¹, Christophe Deligny¹, Philippe Cabre¹ and Michel de Bandt¹, ¹University Hospital Martinique, Fort de France, Martinique
Background/Purpose: Lumbar spinal stenosis (LSS) is a disabling condition, mostly prevalent in the aging population and associated with significant healthcare cost. Clinical presentation involving neurogenic…
Abstract Number: 0591 • ACR Convergence 2020
Intervention to Improve SLE Medication Adherence Using Surescripts Pharmacy Refill Data
Kai Sun¹, Jennifer Rogers², Rebecca Sadun³, Amanda Eudy³, Jayanth Doss³, Lisa Criscione-Schreiber⁴, Ann Cameron Barr⁵, Lena Eder⁶, Mithu Maheswaranathan³, Amy Corneli⁷, Hayden Bosworth¹ and Megan Clowse⁸, ¹Duke University Hospital, Durham, ²Duke University Hospital, Durham, DE, ³Duke University, Durham, NC, ⁴Division of Rheumatology and Clinical Immunology, Department of Medicine, Duke University Medical Center, Durham, NC, ⁵Duke University Hospital, Durham, NC, ⁶Duke University Hospital, Chapel Hill, NC, ⁷Duke University, Durham, ⁸Duke University, Chapel Hill, NC
Background/Purpose: Medication nonadherence is as high as 80% among SLE patients and leads to higher morbidity, mortality, and healthcare costs. Few studies have tested interventions…

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