ACR Meeting Abstracts

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  • Abstract Number: 0362 • ACR Convergence 2024

    Development of a Theory-based Digital Messaging Program to Reduce Fatigue in Systemic Lupus Erythematosus

    Anna Deck1, Paula Caras2, Kiran Singh3, Monique Gore-Massy4, Faye Chiu5, Sara Folta6 and Shanthini Kasturi3, 1Tufts University School of Medicine, Portland, ME, 2Tufts University School of Medicine, Boston, MA, 3Tufts Medical Center, Boston, MA, 4Lupus Foundation of America, New Jersey, 5N/A, New York City, NY, 6Tufts University/Tufts University Friedman School of Nutrition, Boston, MA

    Background/Purpose: Fatigue is the single most prevalent symptom of systemic lupus erythematous (SLE), affecting 80-90% of patients, and is often refractory to pharmacologic therapy. Non-pharmacologic…
  • Abstract Number: 0332 • ACR Convergence 2024

    Predictors of Long-term Radiographic Changes in Patients with Idiopathic Inflammatory Myopathies Using Quantitative Imaging Analysis: Real World Experience from a Single Center Longitudinal Cohort

    Sangmee Bae1, Daniela Macrovic2, Auguestine Chung2, Jessica Channick2, Andrea Oh1, Jennifer Wang1, Ani Shahbazian2, Tiffany De Leon2, Yuna Lee2, Grace Kim2, Donald Tashkin2, Jonathan Goldin2 and christina Charles-Schoeman3, 1UCLA, Los Angeles, CA, 2UCLA, Los Angeles, 3UCLA Medical Center, Santa Monica, CA

    Background/Purpose: Interstitial lung disease (ILD) is a major cause of mortality in idiopathic inflammatory myopathies (IIM), and high-resolution computed tomography (HRCT) is a key modality…
  • Abstract Number: 0284 • ACR Convergence 2024

    Identification of Calcium Pyrophosphate Deposition Using Ultrasonography in Patients with a Suspected Diagnosis of Seronegative Rheumatoid Arthritis

    Joanna Potera1, Angelo Gaffo2, Alvin Day3, Mariana Urquiaga2 and Amanda Alexander4, 1University of Alabama at Birmingham, Irondale, AL, 2University of Alabama at Birmingham, Birmingham, AL, 3Dept. of Veterans Affairs, Lexington, SC, 4University of Alabama at Birmingham, Homewood, AL

    Background/Purpose: Calcium pyrophosphate deposition disease is a common condition that can cause chronic polyarticular inflammatory joint disease, which sometimes resembles rheumatoid arthritis. Misdiagnosis is especially…
  • Abstract Number: 0355 • ACR Convergence 2024

    Improvements in Patient-Reported Outcomes After Treatment with SEL-212 in Adults with Refractory Gout: Results from Two Randomized Phase 3 Trials

    Vibeke Strand1, Puja Khanna2, Alan Kivitz3, Nana Kragh4, Aletta Falk5, Rehan Azeem6, Hugues Santin-Janin7 and Herbert Baraf8, 1Division of Immunology/Rheumatology, Stanford University, Palo Alto, CA, 2University of Michigan, Ann Arbor, MI, 3Altoona Center for Clinical Research, Duncansville, PA, 4Sobi, Kongens Lyngby, Denmark, 5Sobi, Stockholm, Sweden, 6Sobi Inc., Waltham, MA, 7Sobi, BETTENDORF (68560), France, 8Center for Rheumatology and Bone Research, Wheaton, MD

    Background/Purpose: Patients (pts) with gout have impaired health-related quality of life (HRQoL) relating to acute or chronic inflammation from elevated serum uric acid (sUA) levels.…
  • Abstract Number: 0391 • ACR Convergence 2024

    Using Machine Learning to Predict Inactive Disease in Juvenile Idiopathic Arthritis

    Mei-Sing Ong1, Marc Natter2, Laura Schanberg3 and Yukiko Kimura4, and CARRA Registry Investigators, 1Harvard Medical School & Harvard Pilgrim Healthcare Institute, Boston, MA, 2Boston Children's Hospital, Boston, MA, 3Duke University Medical Center, DURHAM, NC, 4Hackensack Meridian School of Medicine, New York, NY

    Background/Purpose: Optimizing treatment of JIA continues to be a challenge. Biologic DMARD (bDMARD) therapies have significantly improved outcomes but is costly, may be more difficult…
  • Abstract Number: 0313 • ACR Convergence 2024

    Cardiac Sarcoidosis Is Associated with a High Mortality: Retrospective Analysis of a Cohort at Mayo Clinic Florida

    Sehreen Mumtaz1, Jayesh Valecha2, Andy Abril3, Florentina Berianu3, Benjamin Wang4, Ronald Butendieck4, anushka Irani2, carolyn mead harvey2 and Vikas Majithia2, 1Mayo Clinic, Florida, Jacksonville, FL, 2Mayo Clinic Florida, Jacksonville, FL, 3Mayo Clinic, Ponte Vedra Beach, FL, 4Mayo Clinic, Jacksonville, FL

    Background/Purpose: Sarcoidosis, characterized by non-necrotizing granulomatous inflammation, is a multisystem disease with an unpredictable disease spectrum. An estimated 5% of sarcoidosis patients have clinically evident…
  • Abstract Number: 0269 • ACR Convergence 2024

    Delphi Survey to Establish Consensus on the OMERACT Core Domain Set for Long-Term Studies of Calcium Pyrophosphate Deposition Disease

    Yiling Zhang1, Sara Tedeschi2, Abhishek Abhishek3, Owen Hensey4, David Grossberg5, Ken Cai6, Beverley Shea7, Jasvinder Singh8, Robin Christensen9, Teodora Serban10, Edoardo Cipolletta11, Konstantinos Parperis12, César Díaz13, Geraldine McCarthy14, Fabio Becce15, Tamer A Gheita16, Silvia Sirotti17, Sara Nysom Christiansen18, Luis Coronel Tarancon19, Lisa Stamp20, Yousra H Abdel-Fattah21, Tristan Pascart22, Georgios Filippou17, Lih En Hong23, John FitzGerald24 and Nicola Dalbeth1, 1University of Auckland, Auckland, New Zealand, 2Brigham and Women's Hospital, Boston, MA, 3University of Nottingham, Nottingham, United Kingdom, 4OMERACT patient research partner, Dublin, Ireland, 5OMERACT patient research partner, Maryland, 6Westmead Hospital, Sydney, New South Wales, Australia, 7Ottawa Hospital Research Institute, Ottawa, ON, Canada, 8Baylor College of Medicine, Birmingham, AL, 9Musculoskeletal Statistics Unit, The Parker Institute, Copenhagen, Denmark, 10Ospedale La Colletta, Bucharest, Romania, 11Polytechnic University of Marche, Ancona, Italy, 12University of Cyprus Medical School, Nicosia, Cyprus, 13Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, 14Mater Misericordiae University Hospital, Dublin, Ireland, 15Lausanne University Hospital (CHUV), Lausanne, Switzerland, 16Rheumatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt, 17IRCCS Galeazzi - Sant'Ambrogio Hospital, Milan, Italy, 18Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark., Glostrup, Denmark, 19Image and Technics Unit, Department of Rheumatology. Hospital Universitari Vall d’Hebron, Barcelona, Spain, 20University of Otago, Christchurch, Christchurch, New Zealand, 21Alexandria University, Alexandria, Egypt, 22Lille Catholic University, Lille, France, 23Royal Adelaide Hospital, Unley Park, South Australia, Australia, 24UCLA, Los Angeles, CA

    Background/Purpose: To agree on important domains for the Outcome Measures in Rheumatology (OMERACT) core domain set for long-term studies of calcium pyrophosphate deposition (CPPD) disease.Methods:…
  • Abstract Number: 0337 • ACR Convergence 2024

    Characterization of Statin Induced Myopathy in the Hospital Setting

    Olivia Yang1, KUMAR VENKAT2, Jeffery Durbin3 and Scott Kubomoto1, 1Riverside Community Hospital, Riverside, CA, 2Voluntary Clinical Associate Professor of Medicine -UCRSOM, Riverside, California, IRVINE, CA, 3HCA Healthcare Physicians Services Group, Brentwood, TN

    Background/Purpose: Adverse effects of statin use involve the muscle and related rhabdomyolysis. Known risk factors for rhabdomyolysis include female sex, older age, Asian race, hypothyroidism,…
  • Abstract Number: 0373 • ACR Convergence 2024

    Enhancing Lupus Patient Education and Support at Kings County Hospital

    Dmytro Gatsak1, Jayashree Gandhi1, Aleksander Feoktistov2, Eugeniya Golub3 and Michael Trevisonno4, 1Kings County Hospital/ SUNY Downstate Medical Center, Brooklyn, NY, 2Kings County Hospital Center/ H+H NYC, Brooklyn, NY, 3Kings County Hospital/ SUNY Downstate Medical Center, Staten Island, NY, 4State University of New York Downstate Medical Center, Brooklyn, NY

    Background/Purpose: Kings County Hospital, located in Brooklyn, New York, sees an estimated 243 patients with Systemic Lupus Erythematosus (SLE) annually. The patient demographic is predominantly…
  • Abstract Number: 0303 • ACR Convergence 2024

    Phase 2b, Long-term Extension, Dose-ranging Study of Oral JNJ-77242113 for the Treatment of Moderate-to-Severe Plaque Psoriasis: FRONTIER-2

    Laura K. Ferris1, Jerry Bagel2, Yu-Huei Huang3, Andrew E. Pink4, Stephen K. Tyring5, Georgios Kokolakis6, Amy M. DeLozier7, Daniel Kakaley8, Shu Li9, Yaung-Kaung Shen10, Takayuki Ota7 and Robert Bissonnette11, 1University of Pittsburgh, Pittsburgh, PA, 2Psoriasis Treatment Center of Central NJ, East Windsor, NJ, 3Chang Gung Memorial Hospital and Chang Gung University, Linkou, Taoyuan City, Taiwan (Republic of China), 4NHS Foundation Trust Great Maze Pond, London, United Kingdom, 5Center for Clinical Studies, Webster, TX, 6Psoriasis Research and Treatment Center, Department of Dermatology, Venereology and Allergology, Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, 7Janssen Research & Development, LLC, San Diego, CA, 8Janssen Scientific Affairs, LLC, Horsham, PA, 9Janssen Research & Development, LLC, Spring House, PA/San Diego, CA, 10Janssen Research & Development, LLC, Spring House, PA, 11Innovaderm Research, Montreal, QC, Canada

    Background/Purpose: JNJ-77242113, a targeted oral peptide, inhibits IL-23 signaling by binding the IL-23 receptor. At all doses, JNJ-77242113 showed superior efficacy at Week 16 versus…
  • Abstract Number: 0360 • ACR Convergence 2024

    What Happens in Rheumatoid Arthritis Treatment Adherence, Two Years After the Introduction of Targeted Therapy? Results from the STRATEGE2 Study

    Cécile Gaujoux-Viala1, Emmanuelle Dernis2, Eric Senbel3 and René-Marc Flipo4, 1CHU Nîmes, Nïmes, Languedoc-Roussillon, France, 2CH LE MANS, LE MANS, Pays de la Loire, France, 3Cabinet de Rhumatologie, Marseille, France, 4Hôpital Roger Salengro, France, Lille, France

    Background/Purpose: Treatment adherence is a major challenge in chronic inflammatory rheumatic diseases, particularly rheumatoid arthritis (RA), with adherence rates ranging from 30 to 80%. Given…
  • Abstract Number: 0347 • ACR Convergence 2024

    Dermato-polymyositis Mortality in U.S. Population: Declining Cancer and Cardiovascular Diseases Among the Leading Underlying Causes of Death over Two Decades

    Elizabeth Matz1 and Ram Singh2, 1UCLA David Geffen School of Medicine, Los Angeles, 2UCLA David Geffen School of Medicine, Los Angeles, CA

    Background/Purpose: Dermatomyositis and polymyositis (DM/PM) are chronic inflammatory muscle diseases that may cause premature death due to progressive muscle weakness, lung disease, and disease and…
  • Abstract Number: 0248 • ACR Convergence 2024

    Recombinant Herpes Zoster Vaccine in a Large Cohort of Autoimmune Rheumatic Diseases Patients: An Interim Analysis of a Prospective Randomized Phase 4 Study

    Nadia Aikawa1, Ana Cristina Medeiros-Ribeiro2, Sandra Pasoto3, Leonard Kupa3, Luciana Seguro4, ANA PAULA ASSAD3, Eduardo Borba3, Carla Goncalves Schahin Saad4, Emily Figueiredo Neves Yuki3, Danieli Andrade5, Andrea Shimabuco4, Karina Bonfiglioli3, Diogo Domiciano3, Julio Moraes3, Samuel Shinjo4, Percival Sampaio-Barros4, Henrique Giardini3, Joao de Oliveira3, Isabele Antonelli3, Renata Pinheiro3, Thais Bonini3, Marta Lopes6, Clovis Silva7 and Eloisa Bonfa3, 1Rheumatology Division and Pediatric Rheumatology Unit, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil, 2Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Jose Dos Campos, Brazil, 3Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, São Paulo, SP, Brazil, 4Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, SP, Brazil, 5University of São Paulo, São Paulo, SP, Brazil, 6Infectious Disease Department, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, São Paulo, SP, Brazil, 7Rheumatology Division and Pediatric Rheumatology Unit, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, SP, Brazil

    Background/Purpose: Patients with autoimmune rheumatic diseases (ARDs) are at high risk of herpes zoster (HZ) due to their condition and treatment. The new recombinant vaccine…
  • Abstract Number: 0343 • ACR Convergence 2024

    An Interlaboratory Variability Study of Detection Methods for Myositis-Specific and Myositis-Associated Autoantibodies in Sera from Patients with Idiopathic Inflammatory Myopathies

    Georgina Harvey1, Idil Ashur2, Xavier Bossuyt3, Martin Bluethner4, Anna Brusch5, Chris Bundell5, hector Chinoy6, Claire Coeshott7, Charmaine Donald2, Juliet Dunphy8, Marvin Fritzler9, Adrian Heaps2, marie Hudson10, Masataka Kuwana11, Océane Landon-Cardinal12, Hui Lu1, FIONNUALA MCMORROW1, Marie Mayrhofer4, Alain Meyer13, Birthe Michiels3, Benoit Nespola14, Susan O'Loughlin15, Ivana Putova16, Johan Rönnelid17, Ross Sadler18, Maria Teresa Sanz-Martinez19, Paul Sciore20, Albert Selva-O’Callaghan21, Helena Storfors22, Ernesto Trallero-Araguás23, Yves Troyanov12, Jade Tyson2, Jiří Vencovský24, Akira Yoshida25 and Sarah Tansley1, 1University of Bath, Bath, United Kingdom, 2Severn Pathology, North Bristol NHS Trust, Bristol, United Kingdom, 3University Hospitals Leuven, Leuven, Belgium, 4MVZ Labor PD Dr. Volkmann und Kollegen GbR, Karlsruhe, Germany, 5Department of Clinical Immunology, PathWest Laboratory Medicine, Perth, Western Australia, Australia, 6The University of Manchester, Manchester, United Kingdom, 7Advanced Diagnostics Laboratories National Jewish Health, Denver, CO, 8Royal United Hospital Bath NHS Foundation Trust, Bath, United Kingdom, 9Mitogen Diagnostics Corp, Calgary, AB, Canada, 10McGill University, Montreal, QC, Canada, 11Department of Allergy and Rheumatology, Nippon Medical School, Tokyo, Japan, Tokyo, Japan, 12Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada, 13UR3072, Physiology Department, Rheumatology Department, University Hospital of Strasbourg, Strasbourg, France, 14Laboratoire d’immunologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, 15Greater Manchester Immunology Service, Manchester, England, United Kingdom, 16Institute of Rheumatology, Prague, Czech Republic, 17Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden, 18Laboratory of Immunology, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, England, United Kingdom, 19Immunology Division, Vall d'Hebron Hospital, Barcelona, Spain, 20Mitogen Diagnostics Corp., Calgary, 21Internal Medicine Department, Universitat Autònoma de Barcelona, Barcelona, Spain, 22Department of Clinical Immunology and Transfusion Medicine, Uppsala University Hospital, Uppsala, Sweden, 23Rheumatology Departament, Vall d'Hebron Hospital, Barcelona, Spain, 24Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, 25Nippon Medical School Graduate School of Medicine, Bunkyo-ku, Tokyo, Japan

    Background/Purpose: In idiopathic inflammatory myopathy (IIM) spectrum diseases, myositis-specific and myositis-associated autoantibodies (MSAs/MAAs) are key markers of disease subtype and prognosis and are considered routine…
  • Abstract Number: 0345 • ACR Convergence 2024

    Treatment Patterns and Glucocorticoid Burden of Dermatomyositis Patients: A Cohort Study in the University of Pittsburgh’s Myositis Registry

    Chester Oddis1, Jan Feifel2, Dana Ascherman3, Diane Carol Koontz4, Caroline Foch2, Luisa Henkel5, Jeffrey M. Muir6, Deborah Denis7 and Rohit Aggarwal8, 1Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 2the healthcare business of Merck KGaA, Darmstadt, Germany, 3Division of Rheumatology and Clinical Immunology, University of Pittsburgh Medical Center, Pittsburgh, PA, 4University of Pittsburgh, Pittsburgh, PA, 5Merck Healthcare Germany GmbH, an affiliate of Merck KGaA, Darmstadt, Germany, Weiterstadt, Germany, 6Cytel, Inc., Toronto, Canada, 7EMD Serono, Rockland, MA, 8Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA

    Background/Purpose: Glucocorticoids (GC) in high doses remain the first-line treatment for dermatomyositis (DM). One or more immunosuppressive agents are given concomitantly as steroid-sparing agents to…
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