Abstracts Archive - Page 600 of 2607 - ACR Meeting Abstracts

Abstract Number: 1759 • ACR Convergence 2022
Factors Affecting Success of Behavioral Interventions to Improve Physical Activity in Patients with Knee Osteoarthritis
Lakshmi Jayaram¹, jing song², Pamela Semanik³, Daniel Pinto⁴, Linda Ehrlich-Jones⁵, Lutfiyya Muhammad⁶, Alison Chang⁶ and Rowland Chang⁷, ¹McGaw Medical Center, Northwestern University, Chicago, IL, ²Northwestern University, Chicago, IL, ³Rush University, Chicago, IL, ⁴Marquette University, Wauwatosa, WI, ⁵Shirley Ryan AbilityLab, Aurora, IL, ⁶Northwestern University Feinberg School of Medicine, Chicago, IL, ⁷Northwestern University Division of Rheumatology, Chicago, IL
Background/Purpose: Knee osteoarthritis (KOA) is a chronic long-term condition that results in pain, disability and reduced quality of life. Over 13 million US adults 45…
Abstract Number: 1749 • ACR Convergence 2022
Mass Spectrometry-Based HLA Peptidomics Analysis Reveals Both Expected and Novel Citrullinated Antigen Targets in Rheumatoid Arthritis
Eddie James¹, Cliff Rims², Sylvia Posso², Jeffrey Carlin³, William Kwok², Shao-En Ong⁴ and Jane Buckner¹, ¹Benaroya Research Institute at Virginia Mason, Seattle, WA, ²Benaroya Research Institute, Seattle, WA, ³Virginia Mason Medical Center, Seattle, WA, ⁴University of Washington, Seattle, WA
Background/Purpose: Rheumatoid arthritis (RA) is an autoimmune disease in which citrullinated self-antigens are recognized by anti-citrullinated protein antibodies (ACPA) and T cells. ACPA are a…
Abstract Number: 1757 • ACR Convergence 2022
The Independent Impact of Gout on Mortality and Risk of Coronary Heart Disease Among Women – a Prospective Cohort Analysis of Women over 34 Years
Chio Yokose¹, natalie mccormick¹, na lu², amit johi³, Gary Curhan⁴ and Hyon Choi⁵, ¹Massachusetts General Hospital, Boston, MA, ²Arthritis Research Canada, Boston, MA, ³Regeneron, Boston, MA, ⁴Brigham and Women's Hospital, Boston, MA, ⁵MASSACHUSETTS GENERAL HOSPITAL, Lexington, MA
Background/Purpose: The disease burden of female gout has increased in recent years.1 However, there remains a paucity of data on female gout, despite it being…
Abstract Number: 1770 • ACR Convergence 2022
Prevalence and Incidence of Depression in Patients with Rheumatoid Arthritis: A Systematic Review
John E Oghene¹, Griffin Reed², Ian Saldanha³, Pooja Reddy⁴, Ahmed Elshazly⁵, Yuvaraj Singh⁶ and Deepan Dalal⁷, ¹Hospital of the University of Pennsylvania, Philadelphia, PA, ²Rhode island hospital, Brown University Warren Alpert School of Medicine, Providence, RI, ³Brown University School of Public Health, Providence, RI, ⁴Rhode island hospital, Brown University Warren Alpert School of Medicine, Seekonk, MA, ⁵Westerly Hospital, Yale New Haven Health, Westerly, RI, ⁶Saint Vincent Hospital, Worcester, MA, ⁷Brown University School of Medicine, Providence, RI
Background/Purpose: Depression is a common co-morbidity that has been shown to worsen symptoms such as pain, fatigue, decreased functional status, decreased disease remission, and response…
Abstract Number: 1764 • ACR Convergence 2022
Utilization of Electronic Health Record Data to Evaluate the Impact of Urban Environment on Risk of Systemic Lupus Erythematosus Symptoms
Janet Song¹, Noah Forrest¹, Kathleen Mittendorf², Wei-Qi Wei², Leah Kottyan³, Rosalind Ramsey-Goldman¹, Theresa Walunas¹ and Abel Kho¹, ¹Feinberg School of Medicine, Chicago, IL, ²Vanderbilt University Medical Center, Nashville, TN, ³Cincinnati Children's Hospital Medical Center, Cincinatti, OH
Background/Purpose: Systemic Lupus Erythematosus (SLE) has a complex and poorly understood etiology and is difficult to diagnose due to its varied presentation across many organ…
Abstract Number: 1766 • ACR Convergence 2022
COVID-19 Cutaneous and Systemic Manifestations Among Race: A Systematic Review and Meta-Analysis
Angie El-Said¹, Areeb Ahmad², Massimo Valenti³, Neel K. Shah¹, Susana Soto¹ and Shazia Beg⁴, ¹University of Central Florida College of Medicine, Orlando, FL, ²University of Central Florida, Orlando, FL, ³Sapienza University of Rome, School of Medicine, Rome, Italy, ⁴UCF, Orlando, FL
Background/Purpose: Although various systemic and dermatologic manifestations associated with COVID-19 have been reported in the literature, investigations of how these manifestations vary by race remain…
Abstract Number: 1762 • ACR Convergence 2022
Stability of Cell Bound Complement Activation Products (CB-CAPs), Multianalyte Assay Panel (MAP) with Algorithm, and Other Autoimmune Biomarkers Among Clinical Patients Throughout the SARS-CoV-2 Pandemic and Vaccination Campaigns
Mark Rudolph, Rory Bloch, Anja Kammesheidt and Roberta Alexander, Exagen, Inc., Vista, CA
Background/Purpose: COVID-19 can cause autoantibody signatures in severely ill patients, and widespread emerging post-acute sequelae of SARS-CoV-2 (PASC) share many symptoms consistent with rheumatologic involvement…
Abstract Number: 1774 • ACR Convergence 2022
Performance of an Early Triage System for Identification of Patients with Inflammatory Rheumatic Diseases
Xenofon Baraliakos¹, Imke Redeker², Maria Zacharopoulou², Styliani Tsiami³ and Juergen Braun⁴, ¹Rheumazentrum Ruhrgebiet Herne, Herne, Germany, ²Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, ³Rheumazentrum Ruhrgebiet, Herne, Ruhr-University Bochum, Herne, Germany, ⁴Rheumazentrum Ruhrgebiet, Herne, Germany
Background/Purpose: The preselection of patients with suspicion of an inflammatory rheumatic disease is not easy for general practitioners and orthopedists. In countries with a limited…
Abstract Number: 1776 • ACR Convergence 2022
COVID-19 Cases in Patients Treated with Secukinumab: Analysis from the Global Safety Database
Atul Deodhar¹, Andrew Blauvelt², Philip J Mease³, Effie Pournara⁴, Piotr Jagiello⁴, Weibin Bao⁵ and Abhishek Sharma⁶, ¹Oregon Health & Science University, Portland, OR, USA, Portland, OR, ²Oregon Medical Research Center, Portland, OR, USA, Portland, OR, ³Swedish Medical Center/Providence St. Joseph Health, Seattle, WA, ⁴Novartis Pharma AG, Basel, Switzerland, ⁵Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁶Novartis Healthcare Pvt. Ltd, Hyderabad, India
Background/Purpose: Although patients (pts) with immune-mediated inflammatory diseases who are taking immunosuppressive therapies are not at a significantly greater risk of SARS-CoV-2 (severe acute respiratory…
Abstract Number: 1773 • ACR Convergence 2022
Epidemiology and Outcomes of Raynaud’s Phenomenon Hospitalizations in the US
Rashmi Dhital¹, Monica Guma², Thuthiri Lwin³, Amar Suwal⁴ and Brian Pedersen¹, ¹UC San Diego, San Diego, CA, ²UCSD, La Jolla, CA, ³University of California San Diego, San Diego, CA, ⁴Reading Hospital, Tower Health, Reading, PA
Background/Purpose: The prevalence of Raynaud's phenomenon (RP) in the general population is ~3-5%, of which 80–90% are primary. Autoimmune diseases are the most common causes…
Abstract Number: 1775 • ACR Convergence 2022
More Than Half of Patients with Osteoarthritis Have Positive Screening for Fibromyalgia And/or Depression, Feasibly Assessed in Routine Care on Indices Within a Single MDHAQ (multidimensional Health Assessment Questionnaire)
Theodore Pincus¹, Kathryn Gibson², Juan Schmukler¹, Tengfei Li³ and Joel Block¹, ¹Rush University Medical Center, Chicago, IL, ²Liverpool Hospital, Sydney, Australia, ³Georgetown University, Washington, DC
Background/Purpose: Osteoarthritis (OA) patients may have widely divergent scores for pain severity vs X-ray joint damage, indicating that elevated OA pain 0-10 visual numeric scale…
Abstract Number: 1271 • ACR Convergence 2022
Uptake of Rheumatology-Specific Quality Measures Submitted to National Pay-for-Performance Programs: An Analysis of Participants in the RISE Registry
Emma Kersey¹, Jing Li², Zara Izadi¹, Julia Adler-Milstein³, Tracy Johansson⁴, Jinoos Yazdany⁵ and Gabriela Schmajuk⁶, ¹University of California San Francisco, San Francisco, CA, ²University of California, San Francisco, San Francisco, CA, ³UCSF, San Francisco, ⁴American College of Rheumatology, Atlanta, GA, ⁵UCSF, San Francisco, CA, ⁶UCSF / SFVA, San Francisco, CA
Background/Purpose: In recent years, the American College of Rheumatology has stewarded a number of rheumatology-specific quality measures for use in national pay-for-performance programs. While the…
Abstract Number: 1716 • ACR Convergence 2022
The Transcriptomic Landscape of Nephritic Kidneys Reveals Mechanisms for End Organ Resistance to Damage in Lupus-prone Mice
Andrea Daamen¹, Hongyang Wang², Prathyusha Bachali³, Shu Man Fu², Amrie Grammer⁴ and Peter Lipsky¹, ¹AMPEL BioSolutions, Charlottesville, VA, ²University of Virginia, Charlottesville, VA, ³AMPEL BioSolutions, Redmond, WA, ⁴AMPEL LLC, Charlottesville, VA
Background/Purpose: Pathologic inflammation is a major driver of kidney damage in lupus nephritis (LN), but the immune mechanisms of disease progression and risk factors for…
Abstract Number: 1666 • ACR Convergence 2022
Differentiation of Injury-associated Macrophages in Lupus Kidneys Is Conserved in Humans and Lupus Mouse Models
Paul Hoover¹, David Lieb², Stephen Li², Chirag Raparia³, Accelerating Medicines Partnership SLE/RA⁴, Arnon Arazi⁵, Nir Hacohen² and Anne Davidson⁶, ¹Brigham and Women's Hospital, Boston, MA, ²Broad Institute, Cambridge, MA, ³Donald and Barbara Zucker School of Medicine At Hofstra/Northwell, Shoreham, NY, ⁴NIH, Bethesda, MD, ⁵Feinstein Institutes for Medical Research, Melrose, MA, ⁶Feinstein Institutes for Medical Research, Manhasset, NY
Background/Purpose: Infiltrating monocytes acquire functions that support kidney remodeling in response to tissue damage in lupus nephritis. This process of monocyte differentiation has been difficult…
Abstract Number: 1523 • ACR Convergence 2022
Anti-RNPC3 Autoantibodies in Mixed Connective Tissue Disease Are Associated with Systemic Sclerosis Skin Involvement
Darya S. Jalaledin¹, Hajar El Kamouni², Alexandra Albert³, Sabrina Hoa⁴, Josiane Bourre-Tessier⁵, Eric Rich⁵, Jean-Richard Goulet⁶, Martial Koenig⁷, Minoru Satoh⁸, Marvin Fritzler⁹, May Choi¹⁰, Yves Troyanov¹¹, Jean-Luc Senécal, MD¹² and Océane Landon-Cardinal⁵, ¹Division of Internal Medicine, Centre Hospitalier de l'Université de Sherbrooke, Saint-Lambert, Canada, ²Division of Rheumatology, Centre Hospitalier de l'Université de Montréal, Laval, Canada, ³Division of Rheumatology, Centre Hospitalier de l'Université Laval, Québec, QC, Canada, ⁴University of Montreal, Montréal, QC, Canada, ⁵Division of Rheumatology, Centre Hospitalier de l'Université de Montréal, Montréal, QC, Canada, ⁶Division of Rheumatology, Centre Hospitalier de l'Université de Montréal, Saint-Lambert, Canada, ⁷Division of Internal Medicine, Centre Hospitalier de l'Université de Montréal, Montréal, QC, Canada, ⁸Department of Human, Information and Science, University of Occupational Environmental Health, Kitakyusyu Fukuoka, Japan, ⁹University of Calgary, Calgary, AB, Canada, ¹⁰Brigham and Women's Hospital | University of Calgary, Calgary, AB, Canada, ¹¹Division of Rheumatology, Hôpital du Sacré-Coeur de Montréal, Montréal, QC, Canada, ¹²Division of Rheumatology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada
Background/Purpose: RNA-binding region containing 3 (RNPC3) protein acts as a molecular bridge, promoting U11/U12 RNP complex formation. In previous studies, systemic sclerosis (SSc) patients who…

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