Abstracts Archive - Page 551 of 2607 - ACR Meeting Abstracts

Abstract Number: 1017 • ACR Convergence 2022
Minimal Important Difference (MID), Minimal Detectable Change (MDC), and Disease Activity Thresholds for Two Novel Composite Instruments (3VAS, 4VAS) in Patients with Psoriatic Arthritis: Pooled Analysis of Three Phase 3 Studies
William Tillett¹, Laura Coates², Marijn Vis³, Joseph Merola⁴, Enrique R Soriano⁵, Michelle Perate⁶, May Shawi⁷, Miriam Zimmermann⁸, Emmanouil Rampakakis⁹, Mohamed Sharaf¹⁰, Peter Nash¹¹ and Philip Helliwell¹², ¹Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, ²Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK, Oxford, England, United Kingdom, ³Erasmus MC Universitair Medisch Centrum, Rotterdam, Netherlands, ⁴Harvard Medical School, Brigham and Women's Hospital, Boston, MA, ⁵Rheumatology Unit and University Institute, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁶Janssen Scientific Affairs, LLC, Horsham, PA, ⁷Immunology Global Medical Affairs, Janssen Pharmaceutical Companies of Johnson & Johnson, Horsham, PA, ⁸Immunology, Janssen Scientific Affairs, LLC, Zug, Switzerland, ⁹McGill University, Department of Pediatrics and JSS Medical Research, Montréal, QC, Canada, ¹⁰Johnson & Johnson, Middle East FZ LLC, Dubai, United Arab Emirates, ¹¹School of Medicine, Griffith University, Sunshine Coast, Australia, ¹²Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom
Background/Purpose: Though continuous composite measures of disease activity for psoriatic arthritis (PsA) assessment exist, abbreviated measures that are more feasible for screening in routine clinical…
Abstract Number: 1028 • ACR Convergence 2022
How Does PsAID Implementation Affect Treatment Intensification and Patient Satisfaction in PsA?
Conor Coyle¹, Caroline Whately-Smith², Melanie Brooke³, Uta Kiltz⁴, Ennio Lubrano⁵, Ruben Queiro⁶, David Trigos⁷, Jan Brandt-Juergens⁸, Salvatore D'Angelo⁹, Andrea Delle Sedie¹⁰, Emmanuelle Dernis¹¹, Philip Helliwell¹², Pauline Ho¹³, Axel Hueber¹⁴, BEATRIZ E. JOVEN¹⁵, Michaela Koehm¹⁶, Carlos Montilla¹⁷, Jon Packham¹⁸, JOSE PINTO TASENDE¹⁹, Felipe Julio Ramirez Garcia²⁰, Adeline Ruyssen-Witrand²¹, Rossana Scrivo²², sarah twigg²³, Martin Welcker²⁴, Theo Wirth²⁵, Laure Gossec²⁶ and Laura Coates²⁷, ¹Oxford University Hospitals NHS Trust, Oxford, United Kingdom, ²Whately-Smith Ltd, Kings Langley, United Kingdom, ³Bath Institute for Rheumatic Disease, Bath, United Kingdom, ⁴Rheumazentrum Ruhrgebiet, Herne, Germany, ⁵Academic Rheumatology Unit, Dipartimento di Medicina e Scienze della Salute ‘‘Vincenzo Tiberio’’, Università degli Studi del Molise, Campobasso, Italy, ⁶Faculty of Medicine, Rheumatology Service & the Principality of Asturias Institute for Health Research (ISPA), Universidad de Oviedo, Oveido, Spain, ⁷Patient partner, Oveido, Spain, ⁸Rheumatologische Schwerpunktpraxis, Berlin, Germany, ⁹Rheumatology Department of Lucania - San Carlo Hospital of Potenza, Potenza, Italy, ¹⁰University of Pisa, Pisa, Pisa, Italy, ¹¹LE MANS general hospital, LE MANS, France, ¹²Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ¹³The Kellgren Centre for Rheumatology, Manchester, United Kingdom, ¹⁴Paracelsus University Nürnberg, Erlangen, Germany, ¹⁵Hospital Universitario 12 de Octubre, Madrid, Spain, ¹⁶Rheumatology Goethe-University Frankfurt, Frankfurt Am Main, Germany, ¹⁷Complejo asistencial Universitario de Salamanca, Salamanca, Spain, ¹⁸University of Nottingham, Stafford, United Kingdom, ¹⁹SERGAS, A Coruña, Spain, ²⁰Hospital Clínic, Barcelona, Spain, ²¹CHU de Toulouse, Toulouse, France, ²²Rheumatology Unit, Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy, Roma, Rome, Italy, ²³Bradford Teaching hospitals NHS foundation trust, Bradford, United Kingdom, ²⁴GBR, Planegg, Germany, ²⁵Aix Marseille University, Marseille, France, ²⁶Sorbonne Université, Paris, France, ²⁷Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK, Oxford, England, United Kingdom
Background/Purpose: Psoriatic arthritis (PsA) is a heterogenous, multi-dimensional disease. Little is known about factors underpinning treatment intensification in routine practice. Treatment pathways are not well…
Abstract Number: 1030 • ACR Convergence 2022
Diagnostic Usefulness of Anti-PPM1A-IgM in Patients with Ankylosing Spondylitis
Yeo jin lee¹, Eun-Ju Lee², Soo Min Ahn², Seokchan Hong², Ji Seon Oh³, Chang Keun Lee², Bin Yoo² and Yong Gil Kim², ¹Asan medical center, Seoul, Republic of Korea, ²Department of Rheumatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea, Seoul, Republic of Korea, ³Department of Information Medicine, Big Data Research Center, Asan Medical Center, Seoul, Republic of Korea
Background/Purpose: Ankylosing spondylitis (AS) has been known to have auto-inflammatory nature, hence, the efficacy of autoantibodies is low. However, studies on autoantibodies are ongoing, with…
Abstract Number: 1022 • ACR Convergence 2022
Validation of the SPARCCRETIC E-Tool for Ensuring Scoring Proficiency of MRI Lesions in Axial Spondyloarthritis
Walter P Maksymowych¹, Anna Hadsbjerg², Mikkel Østergaard³, Raphael Micheroli⁴, Susanne J. Pedersen⁵, Adrian Ciurea⁶, Nora Vladimirova², Michael Nissen⁷, Kristyna Bubova⁸, Stephanie Wichuk⁹, Manouk de Hooge¹⁰, Ashish J Mathew¹¹, Karlo Pintaric¹², Monika gregova¹³, Ziga Snoj¹², Marie Wetterslev¹⁴, Karel Gorican¹⁵, Joel Paschke¹⁶, Iris Eshed¹⁷ and Robert G Lambert⁹, ¹Department of Medicine, University of Alberta, Edmonton, AB, Canada, ²Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ³Rigshospitalet, University of Copenhagen, Glostrup, Denmark, ⁴University Hospital Zurich, Department of Rheumatology, Zürich, Switzerland, ⁵Rigshospitalet, University of Copenhagen, Copenhagen, Denmark, ⁶University Hospital Zurich, Zürich, Switzerland, ⁷Hopitaux Universitaires de Genève, Geneva, Switzerland, ⁸First Faculty of Medicine, Charles University,, Prague, Czech Republic, ⁹University of Alberta, Edmonton, AB, Canada, ¹⁰Ghent University Hospital, Luxembourg, Luxembourg, ¹¹Rigshospitalet, Copenhagen, Denmark, ¹²Radiology, University Medical Centre Ljubljana, Ljubljana, Slovenia, ¹³Institue of Rheumatology, Prague, ¹⁴Rigshospitalet, Copenhagen, Glostrup, Denmark, ¹⁵MSK radiology unit, Radiology section – Diagnostic department, Geneva University Hospitals, Geneva, Switzerland, ¹⁶CARE Arthritis LTD, Edmonton, AB, Canada, ¹⁷Sheba Medical Center, Tel Aviv, Israel
Background/Purpose: Quantification of inflammatory and structural lesions in the sacroiliac joints (SIJ) on MRI scans from patients with axial spondyloarthritis (axSpA) has a growing list…
Abstract Number: 1021 • ACR Convergence 2022
Depression as a Modulator of Patient Reported, but Not Physician Observed, Outcomes in Psoriatic Arthritis
Rebecca Haberman¹, Seungha Um², Sydney Catron¹, Eileen Lydon³, Malavika Attur², Andrea Neimann², Soumya Reddy⁴, Andrea Troxel¹, Samrachana Adhikari¹ and Jose Scher⁵, ¹NYU Langone Health, New York, NY, ²NYU Langone, New York, NY, ³New York University, New York, NY, ⁴NYU School of Medicine, New York, NY, ⁵New York University School of Medicine, New York, NY
Background/Purpose: Psoriatic arthritis (PsA) is a complex immune-mediated disease. Beyond its deleterious effects in the skin and joints, PsA can lead to decreased quality of…
Abstract Number: 1026 • ACR Convergence 2022
Responsiveness and Minimal Clinically Important Difference in Patient-Reported Outcome Measures Among Patients with Psoriatic Arthritis
Paras Karmacharya¹, Courtney Stull², Alisa Stephens-Shields³, M. Elaine Husni⁴, Jose Scher⁵, Ethan Craig⁶, Robert Fitzsimmons³, Soumya Reddy⁷, Marina Magrey⁸, Alexis Ogdie⁹ and Jessica Walsh¹⁰, ¹Vanderbilt University, Nashville, TN, ²University of Pittsburgh, Pittsburgh, PA, ³University of Pennsylvania, Philadelphia, ⁴Cleveland Clinic, Cleveland, OH, ⁵New York University School of Medicine, New York, NY, ⁶University of Pennsylvania, Wallingford, PA, ⁷NYU School of Medicine, New York, NY, ⁸Case Western Reserve University, University Hospitals, Richfield, OH, ⁹Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, ¹⁰University of Utah, Salt Lake City, UT
Background/Purpose: Despite significant heterogeneity in psoriatic arthritis (PsA), randomized controlled trials (RCTs) generally enroll a homogenous subgroup of PsA patients (polyarticular similar to rheumatoid arthritis).…
Abstract Number: 1029 • ACR Convergence 2022
Virtual Assessment in Axial Spondyloarthritis: Validation of Video Observation of Spinal Metrology
Laura Passalent¹, Sareh Keshavarzi¹, Robert Inman¹ and Nigil Haroon², ¹University Health Network, Toronto, ON, Canada, ²Schroeder Arthritis Institute, University Health Network; University of Toronto, Toronto, ON, Canada
Background/Purpose: A shift to virtual clinical encounters was required because of the COVID-19 pandemic. To date, there have been few studies exploring the utility of…
Abstract Number: 1024 • ACR Convergence 2022
Number of Patients with Psoriatric Arthritis (PsA) in Germany Until 2040: Projection Based on Data from 65 Million People in the German Statutory Health Insurance
Philipp Sewerin¹, stephanie Knippschild², Sabrina Tulka², Xenofon Baraliakos³ and Ralph Brinks², ¹Rheumazentrum Ruhrgebiet, Ruhr-Universität-Bochum, Herne, Germany, ²Chair for Medical Biometry and Epidemiology, Witten, Germany, ³Rheumazentrum Ruhrgebiet Herne, Herne, Germany
Background/Purpose: Recently, we have reported an increase in the incidence and prevalence of patients with PsA in Germany based on claim data from 65 million…
Abstract Number: 1019 • ACR Convergence 2022
Association Between Stringent Clinical Measures of Disease Activity and Clinically Meaningful Improvements in Patient-Reported Outcomes in Psoriatic Arthritis: Results from KEEPsAKE 1 and 2 Clinical Trials
Alexis Ogdie¹, Joseph Merola², Roberto Ranza³, Ahmed Soliman⁴, Manish Mittal⁴, Byron Padilla⁵, Sandra Ciecinski⁶, Priscila Nakasato⁷ and Laure Gossec⁸, ¹Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, ²Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ³Serviço de Reumatología, Universidade Federal de Uberlândia, Uberlândia, Brazil, ⁴AbbVie, Inc., North Chicago, IL, ⁵AbbVie, Inc., Waukegan, IL, ⁶AbbVie, Inc., Mettawa, IL, ⁷AbbVie Inc, Toronto, ON, Canada, ⁸Sorbonne Université, Paris, France
Background/Purpose: Assessment of disease activity in PsA patients is important to evaluate therapeutic response in clinical trials. Patient-reported outcomes (PROs) are evaluated to assess benefits…
Abstract Number: 1020 • ACR Convergence 2022
Screening Tools for Spondyloarthritis in Patients with Psoriasis, IBD, and Uveitis – A Scoping Review
Vartika Kesarwani¹, Stephanie Sinnappan², M. Elaine Husni³, Michael Weisman⁴ and Joerg Ermann⁵, ¹University of Connecticut, Farmington, CT, ²Brigham and Women's Hospital, Boston, MA, ³Cleveland Clinic, Cleveland, OH, ⁴Adjunct Professor of Medicine, Stanford University; Distinguished Professor of Medicine Emeritus, David Geffen School of Medicine at UCLA, Los Angeles, CA, ⁵Brigham and Women's Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Extra-articular manifestations of spondyloarthritis (SpA) may precede the development of articular features. Patients seen in dermatology, gastroenterology, and ophthalmology clinics for psoriasis, IBD, or…
Abstract Number: 1018 • ACR Convergence 2022
Characterization of Joint Distribution and Disease Burden in Patients with Early Oligoarticular Psoriatic Arthritis: Results from the Ongoing FOREMOST Study
Dafna Gladman¹, Laura Coates², Laure Gossec³, Jacob Aelion⁴, Jitendra Vasandani⁵, Sue Cheng⁶, Lihua Tang⁶, Shauna Jardon⁷, Sven Richter⁶ and Philip J Mease⁸, ¹Toronto Western Hospital, Schroeder Arthritis Institute, Toronto, ON, Canada, ²Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK, Oxford, England, United Kingdom, ³Sorbonne Université, Paris, France, ⁴West Tennessee Research Institute, Jackson, TN, ⁵West Texas Clinical Research, Lubbock, TX, ⁶Amgen, Inc., Thousand Oaks, CA, ⁷Amgen Inc., Gilbert, AZ, ⁸Swedish Medical Center/Providence St. Joseph Health, Seattle, WA
Background/Purpose: Oligoarticular psoriatic arthritis (PsA) is commonly reported in early disease. Although fewer joints are involved, there may be significant impact on patients’ (pts) quality…
Abstract Number: 1031 • ACR Convergence 2022
Foot Involvement in Psoriatic Arthritis- a Retrospective Study
Sofia Ferreira Azevedo¹, Carolina Mazeda², Susana P. Silva³, Claudia P. Oliveira¹ and Anabela Barcelos³, ¹Rheumatology Department, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal, ²Centro Hospitalar Baixo Vouga, Ovar, Portugal, ³Centro Hospitalar Baixo Vouga, Aveiro, Portugal
Background/Purpose: Foot involvement is well recognized in many inflammatory rheumatic diseases, namely in Spondylarthritis (SpA), where its early recognition is of utmost importance. Psoriatic arthritis…
Abstract Number: 1025 • ACR Convergence 2022
Entheseal Biopsy Approach: An Ultrasound-guided Method for Retrieval of Entheseal Tissue from Psoriatic Arthritis Patients
Maria Gabriella Raimondo¹, Milena Pachowsky¹, Cong Xu¹, Simon Rauber¹, Koray Tascilar¹, Hannah Labinsky², Mario Vogg¹, Mina Saad Aziz Saad¹, David Simon¹, Juergen Rech³, Alina Soare¹, Lars Braeuer⁴, Arnd Kleyer¹, Georg Schett⁵ and Andreas Ramming¹, ¹Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; Deutsches Zentrum Immuntherapie, Friedrich-Alexander-UniversityErlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, ²Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; Deutsches Zentrum Immuntherapie, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, ³University Clinic Erlangen, Erlangen, Germany, ⁴Institute of Anatomy, Chair II, Friedrich-Alexander-Universitat Erlangen-Nurnberg, Erlangen, Germany, ⁵Universitätsklinikum Erlangen, Erlangen, Germany
Background/Purpose: Enthesitis as hallmark feature of psoriatic arthritis (PsA) has been mostly addressed through clinical assessment and imaging evaluation, such as MRI or musculoskeletal ultrasound.…
Abstract Number: 1027 • ACR Convergence 2022
Low Dose Computed Tomography Hounsfield Units: A Reliable Methodology for Assessing Changes in Vertebral Bone Density in Radiographic Axial Spondyloarthritis
Mary Lucy Marques¹, Nuno Pereira da Silva², Désirée van der Heijde³, Monique Reijnierse⁴, Juergen Braun⁵, Xenofon Baraliakos⁶, floris van Gaalen⁴ and Sofia Ramiro⁴, ¹Leiden University Medical Center, Coimbra, Portugal, ²Radiology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, ³Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands, ⁴Leiden University Medical Center, Leiden, Netherlands, ⁵Rheumazentrum Ruhrgebiet, Herne, Germany, ⁶Rheumazentrum Ruhrgebiet Herne, Herne, Germany
Background/Purpose: In radiographic axial Spondyloarthritis (r-axSpA), low dose Computed Tomography (ldCT) Hounsfield Units (HU) were shown to cross-sectionally reliably assess bone density at each vertebra…
Abstract Number: 1023 • ACR Convergence 2022
Are We Treating-to-target in Spondyloarthritis (SpA)? A Cross Sectional Analysis from the Asia Pacific League of Associations for Rheumatology (APLAR) SpA Registry
Isaac Cheng¹, Ying Ying Leung², Ho SO¹, Praveena Chiowchanwisawakit³, Stanley Angkodjojo⁴, Muhammad Saeed⁵, Kichul Shin⁶, Han Joo Baek⁷, Mohit Goyal⁸, Muhammad Haroon⁹, Eman Satti¹⁰, Nallasivan Subramanian¹¹, Fariz Yahya¹², Soosan Soroosh¹³, ASAL ADNAN RIDHA¹⁴, Ho Yin Chung¹⁵, James Cheng-Chung WEI¹⁶, Kishimoto Mitsumasa¹⁷ and Lai-shan Tam¹, ¹The Chinese University of Hong Kong, Hong Kong, China, ²Rheumatology Department, Singapore General Hospital, Singapore, Singapore, ³Mahidol University, Bangkok, Thailand, ⁴Sengkang General Hospital / Singhealth, Singapore, Singapore, ⁵Central Park Medical College, Lahore, Pakistan, ⁶Seoul Metropolitan Government- Seoul National University Boramae Medical Center, Seoul, Republic of Korea, ⁷Gachon University College of Medicine, Inchon, Republic of Korea, ⁸CARE Pain & Arthritis Centre, Udaipur, India, ⁹Doctor, Tralee, Ireland, ¹⁰Hamad Medical Corporation, Doha, Qatar, ¹¹Velammal Medical College Hospital, Velammal, India, ¹²University of Malaya, Kuala Lumpur, Malaysia, ¹³Army University for Medical School, Tehran, Iran, ¹⁴Baghdad Teaching Hospital, Baghdad, Iraq, ¹⁵Chiron Medical, Hong Kong, Hong Kong, ¹⁶Chung Shan Medical University Hospital, Taichung, Taiwan, ¹⁷Department of Nephrology and Rheumatology, Kyorin University School of Medicine, Tokyo, Japan
Background/Purpose: Data on the extent to which internationally agreed treat-to-target (T2T) recommendations were applied in clinical practice in patients with SpA across the Asia-Pacific region…

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