ACR Meeting Abstracts

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  • Abstract Number: PP08 • ACR Convergence 2023

    Finding Gratitude in Adversity: The Impact of Finding the Right Rheumatologist

    Yaideliz Acevedo, Global Healthy Living Foundation, Newark, NJ

    Background/Purpose: I recall sitting in the doctor's office with my one-month-old baby in his stroller, hearing the words "You have rheumatoid arthritis." At 21, I…
  • Abstract Number: PP01 • ACR Convergence 2023

    You Can’t Get This from a Doctor: The Role of Support Groups for Adults Aged 25-55 Living with Arthritis

    Eileen Davidson, Global Healthy Living Foundation, Burnaby, BC, Canada

    Background/Purpose: Living with a rheumatic condition comes with unique concerns specific to mental and social health like struggling with fatigue, anxiety, depression, and isolation, all…
  • Abstract Number: PP14 • ACR Convergence 2023

    Putting Lived Experience into Action: Flipping the Script on Living with a Chronic Disease

    Natasha Trehan1 and Naomi Abrahams2, 1University of Ottawa, Take a Pain Check Foundation, Toronto, ON, Canada, 2University of Ottawa, Ottawa, ON, Canada

    Background/Purpose: Naomi was diagnosed with Juvenile Idiopathic Arthritis (JIA) at the age of 18, after enduring 3 years of misdiagnoses. Similarly, Natasha received a diagnosis…
  • Abstract Number: 2604 • ACR Convergence 2023

    Premature Vascular Smooth Muscle Cells Senescence Driven by Interleukin-6-Mitochondrial STAT3-Mitofusin 2 Signaling in Takayasu’s Arteritis

    Chenglong Fang1, Lihong Du1, Lili Li2, Yuexin Chen3, Zuoguan Chen4, Yongjun Li4, Jing Li1, Mengtao Li5, xiaofeng Zeng6 and Xinping Tian5, 1Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China, 2The State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, Beijing, China, 3Department of Vascular Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China, 4Department of Vascular Surgery, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China, 5Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, 6Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China

    Background/Purpose: Takayasu’s arteritis (TAK) is characterized by persistent vascular inflammation involving aorta and its main branches, which is an important prosenescent factor that in turn…
  • Abstract Number: PP09 • ACR Convergence 2023

    Practicing Mindfulness to Improve Quality of Life

    Vanessa Patino-Lydia, Global Healthy Living Foundation, Hallandale, FL

    Background/Purpose: I’ve been living with symptoms of PSA and fibromyalgia for over 15 years. Four years ago, after flareup that severely impacted my mobility where…
  • Abstract Number: 2351 • ACR Convergence 2023

    Health Outcomes Among Patients (Pts) with SLE Initiating Belimumab (BEL) with and Without the Use of Immunosuppressants in the Previous 2 Years

    Yan Chen1, Karen Worley2, Brendan Rabideau1, Bernard Rubin3, Benson Wu1, Rose Chang1 and Maral DerSarkissian1, 1Analysis Group, Boston, MA, 2GlaxoSmithKline, US Value Evidence and Outcomes, Cincinnati, OH, 3GlaxoSmithKline, US Medical Affairs and Immuno-inflammation, Durham, NC

    Background/Purpose: BEL efficacy in pts with SLE has been previously demonstrated in clinical and real-world studies.1 However, there are limited data on differences in outcomes…
  • Abstract Number: 2365 • ACR Convergence 2023

    Decoding the Peripheral Immune Landscape of Systemic Sclerosis to Investigate Disease Stages and Interstitial Lung Disease Progression

    Vasuki Ranjani Chellamuthu1, Maria Noviani2, Ahmad bin Mohamed Lajam1, Andrea Hsiu Ling Low2 and Salvatore Albani1, 1Translational Immunology Institute, SingHealth, Singapore, Singapore, 2Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore

    Background/Purpose: Systemic sclerosis (SSc) is a heterogenous autoimmune disease characterized by fibrosis, vascular abnormalities and immune dysregulation. Characterization of peripheral blood immune signatures in relation…
  • Abstract Number: 2362 • ACR Convergence 2023

    Identification of Protein Biomarkers Associated with the Severity and Risk of Progression of Interstitial Lung Disease in VEDOSS and Established Systemic Sclerosis Patients

    Thierry Sornasse1, Vishal Kakkar2, Rebecca Ross3, Sunhwa Kim4 and Francesco Del Galdo5, 1AbbVie, Inc., North Chicago, IL, 2University of Leeds, Leeds, United Kingdom, 3Medicine and Health, University of Leeds, Leeds, United Kingdom, 4AbbVie, Inc., South San Francisco, CA, 5University of Leeds - Leeds Institute of Rheumatic and Muskuloskeletal Medicine, Leeds, United Kingdom

    Background/Purpose: Pulmonary Fibrosis (PF) is one of the primary causes of systemic sclerosis (SSc)-related death. Hence, monitoring and predicting the course of PF in SSc…
  • Abstract Number: 2482 • ACR Convergence 2023

    Preinflammatory Mesenchymal (PRIME) Cell Signature Genes Enrichment Predicts Treatment Response and Joint Prognosis in Rheumatoid Arthritis

    Takayuki Fujii1, Dana Orange2, Caryn Hale2, Koichi Murata1, Hideo Onizawa1, Akira Onishi1, Masao Tanaka3, Akio Morinobu4 and Shuichi Matsuda5, 1Department of Advanced Medicine for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 2Rockefeller University, New York, NY, 3Graduate School of Medicine, Kyoto University, Kyoto, Japan, 4Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 5Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

    Background/Purpose: This study aimed to determine predictors of treatment response and radiographic progression following the initiation of biological disease-modifying antirheumatic medications (bDMARDs) in patients with…
  • Abstract Number: 2359 • ACR Convergence 2023

    Reversal of the Activation State of Pro-fibrotic CD206 Positive Macrophages by Therapeutic Peptide AUR300 in Systemic Sclerosis

    Sandra Lopez1, Bahja Ahmed Abdi1, Linda Lei1, Anas Al-Oweidi1, Claire Macfadyen1, Lydia Nagib1, Sarah Ive1, Anshul Kumar1, Teresa Collins1, Jennifer Cross2, Christopher Denton1, David Abraham1, Clayton Yates3, Charles Garvin4, Henry Lopez4, George Martin5 and Richard Stratton1, 1University College London, London, United Kingdom, 2Aurinia Pharmaceuticals Inc., Rockford, MD, 3Tuskegee University, Tuskegee, AL, 4Riptide Bioscience Inc., Valejo, CA, 5Riptide Bioscience Inc., Bethesda, MD

    Background/Purpose: A spectrum of macrophage activation is seen in human pathologic conditions; M2-like CD206 positive macrophages are pro-fibrotic and proresolution, while M1-like macrophages are proinflammatory,…
  • Abstract Number: PP03 • ACR Convergence 2023

    Lupus with Slime: Improve QOL and Increase ROM in SLE with Slime

    Amanda Greene, Los Angeles, CA

    Background/Purpose: In 1983, over forty years ago, I was diagnosed with Systemic Lupus Erythematosus (SLE).  I was immediately prescribed high dose corticosteroids.  My body and…
  • Abstract Number: PP13 • ACR Convergence 2023

    My Four Pillars of Wellness: How Sleep, Diet, Exercise and Stress Reduction Enable Me to Define My Life and not let Sjögren’s Define Me

    Lisa Rubenstein, Sjögren's Foundation, Los Angeles, CA

    Background/Purpose: Being diagnosed with Sjögren’s has been a life changing event for me.I was diagnosed in 2013 after suffering from various odd ailments. Ultimately, extreme…
  • Abstract Number: 2478 • ACR Convergence 2023

    Effect of Conventional and Biologic Disease-Modifying Anti-Rheumatic Drugs on the Antibody Response to Four Doses of COVID-19 mRNA Vaccines in Children with Autoimmune and Rheumatic Diseases

    Janna Shapiro1, Florence Choi2, Amy Xu3, Trang Duong4, Anne-Claude Gingras5, Sasha Bernatsky6, Susanne (Susa) Benseler7 and Rae Yeung8, 1University of Toronto, Toronto, ON, Canada, 2Hong Kong Hospital Authority, Hong Kong, Hong Kong, 3Division of Rheumatology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada, 4The Hospital for Sick Children, Toronto, ON, Canada, 5Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital Sinai Health, Toronto, ON, Canada, 6Research Institute of the McGill University Health Centre, Montreal, QC, Canada, 7University of Calgary, Calgary, AB, Canada, 8The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Children with rheumatic and autoimmune diseases are often treated with conventional or biologic disease-modifying antirheumatic drugs (cDMARDs and bDMARDs) to control disease. While effective,…
  • Abstract Number: 2182 • ACR Convergence 2023

    Mitochondrial Alterations in Primary Sjögren´s Syndrome

    Pavlina Javorova1, Johannes Fessler1, Melanie Zeiler1, Angelika Lackner1, Josef Hermann2, Sabine Zenz3, Jens Thiel4 and Martin Stradner1, 1Medical University of Graz, Graz, Austria, 2Division of Rheumatology and Immunology, Department of Internal Medicine, Medical University Graz, Graz, Austria, 3Medical University Graz, Graz, Austria, 4University Hospital Freiburg, Freiburg, Germany

    Background/Purpose: Primary Sjögren's Syndrome (pSS) is a systemic autoimmune disorder characterized by lymphocytic infiltrations in exocrine glands. T-cells are considered major players in the pathogenesis…
  • Abstract Number: 1774 • ACR Convergence 2023

    Gut Microbiota and Permeability Biomarkers for Diagnosis and Prognosis in Rheumatoid Arthritis Associated Interstitial Lung Disease

    José Lisbona-Montañez1, Patricia Ruiz-Limon2, Arkaitz Mucientes3, Natalia Mena Vazquez4, Isabel Moreno-Indias3, SARA MANRIQUE5, Laura Cano-García6, Rocío Redondo-Rodríguez6, Francisco J tinahones3 and Antonio Fernandez-Nebro7, 1Universidad de Málaga, Departamento de Medicina y Dermatología, Moclinejo, Spain, 2IBIMA Plataforma BIONAND, Cordoba, Spain, 3IBIMA Plataforma BIONAND, Málaga, Spain, 4IBIMA, Málaga, Spain, 5Division of Rheumatology, Hospital Regional Universitario Carlos Haya, Malaga, Spain, 6Division of Rheumatology, Hospital Regional Universitario Carlos Haya, Málaga, Spain, 7Hospital Regional Universitario de Málaga, Malaga, Spain

    Background/Purpose: Gut microbiota has been related to rheumatoid arthritis (RA), inflammation, and it's severity. Interstitial lung disease (ILD) is the most frequent non-pleural pulmonary manifestation…
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Embargo Policy

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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