ACR Meeting Abstracts

ACR Meeting Abstracts

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  • Abstract Number: 1948 • ACR Convergence 2023

    The Influence of Specific Myositis Antibodies on the Development of Interstitial Lung Disease

    Ting-Yuan Lan1, Tai-Ju Lee1, Kuan-Yen Lin2, Jui-Hung Kao3, Chiao-Feng Cheng4, Cheng-Hsun Lu4, Chieh-Yu Shen4, Ko-Jen Li4 and Song-Chou Hsieh4, 1National Taiwan University Hospital Hsinchu Branch, Hsinchu City, Taiwan, 2National Taiwan University Hsinchu branch, Hsinchu, Taiwan, 3National Taiwan University Hospital Yunlin branch, Yunlin, Taiwan, 4National Taiwan University Hospital, Taipei, Taiwan

    Background/Purpose: Interstitial Lung Disease (ILD), prevalent in Idiopathic Inflammatory Myositis (IIM) patients, significantly impacts prognosis. Certain myositis-specific antibodies, including anti-MDA5 and anti-aminoacyl-tRNA synthetases (ARS), are…
  • Abstract Number: 2010 • ACR Convergence 2023

    B-FROST: Chronic OBstructive Pulmonary Disease and Vertebral FRacture of OSTeoporotic Origin: Results of a Real-life Cohort

    Amine Mouamnia, Armentieres Hospital Center, Armentieres, France

    Background/Purpose: Chronic obstructive pulmonary disease (COPD) is a chronic disease of the airways. It is mainly caused by smoking. Active smoking is a risk factor…
  • Abstract Number: 1990 • ACR Convergence 2023

    Effects of Exercise on Movement-Evoked Pain in People with Knee Osteoarthritis

    Ehyun Kim1, Tuhina Neogi2, Benjamin Senderling1, Mary Gheller1, Lee Marinko1, Michael LaValley3, Lukas Adamowicz4, Pirinka Georgiev4, Charmaine Demanuele4, Paul Wacnik4 and Deepak Kumar1, 1Boston University, Boston, MA, 2Boston University School of Medicine, Boston, MA, 3Boston University School of Public Health, Arlington, MA, 4Pfizer Inc., Cambridge, MA

    Background/Purpose: Movement-evoked pain (MEP), i.e., pain that appears with or is made worse by movement, is a common complaint in people with knee osteoarthritis (OA).…
  • Abstract Number: 1799 • ACR Convergence 2023

    Association of Pregabalin vs Gabapentin with Incident Congestive Heart Failure in Patients with Non-Cancer Pain

    Elizabeth Park1, Laura Daniel2, Alyson Dickson3, Meghan Corriere4, Puran Nepal5, Kathi Hall4, Dale Plummer4, William Dupont4, Katherine Murray4, C. Michael Stein3, Wayne Ray4 and Cecilia Chung6, 1Columbia University Irving Medical Center, New York, NY, 2University of Miami, Nashville, TN, 3Vanderbilt University Medical Center, Nashville, TN, 4Vanderbilt University, Nashville, TN, 5University of Miami Health System and Miller School of Medicine, Miami, FL, 6University of Miami, Miami, FL

    Background/Purpose: Chronic pain affects 30% of all patients in developed countries, accounting for up to 35% of prescriptions in acute care settings. Non-opioid pain medications…
  • Abstract Number: 2013 • ACR Convergence 2023

    Clinical Characteristics and Risk Factors Associated with Fragility Fractures in Patients with Primary and Idiopathic Mast Cell Activation Syndromes

    Ana Isabel Ramos Lisbona1, Karen Carpio Astudillo1, Filip Skrabski1, Alicia Prieto García1, Isabel Castrejon1, Javier Rivera2, José María Álvaro-Gracia1 and Teresa González1, 1Hospital General Universitario Gregorio Marañón, Madrid, Spain, 2Hospital General Universitario Gregorio Marañon, Madrid, Spain

    Background/Purpose: Mast Cell Activation Syndromes (MCAS) are a group of disorders presenting with episodic multisystem symptoms, predominantly anaphylaxis, as the result of mast cell mediator…
  • Abstract Number: 1912 • ACR Convergence 2023

    Impact of Pharmacist-Led Specialty Medication Management Service on Time-to-Dispense for Specialty Rheumatologic Medications in a University Health System

    Khashayar Ahmadmehrabi1, Navin Ravishankar2, Diana Mekhiel3 and Zineb Aouhab3, 1Loyola University Medical Center, Oak Park, IL, 2Indiana University Health, Indianapolis, IN, 3Loyola University Medical Center, Maywood, IL

    Background/Purpose: Given the progressive joint damage and physical disability associated with uncontrolled Rheumatoid arthritis (RA), a treat-to target-strategy through the early utilization of disease-modifying antirheumatic…
  • Abstract Number: 1778 • ACR Convergence 2023

    Role of GITR/GITRL Interaction in Modulating T Helper 9, T Helper 17 and T Regulatory Response in Psoriatic Arthritis

    Chiara Rizzo1, Lidia La Barbera1, Marianna Lo Pizzo1, Leila Mohammadnezhad1, federica Camarda1, Francesco Dieli1, Francesco Ciccia2 and Giuliana Guggino1, 1University of Palermo, Palermo, Italy, 2University of Campania - Luigi Vanvitelli, Naples, Italy

    Background/Purpose: The inflammatory process characterizing Psoriatic Arthritis (PsA) is mainly driven by interleukin (IL)-23/IL-17 axis and IL-9 overexpression, in presence of T helper (Th)17 and…
  • Abstract Number: 1953 • ACR Convergence 2023

    Mortality Trends in Polymyositis and Dermatomyositis in Mexico: A General Population-based Study from 2000 to 2019

    CLAUDIA MENDOZA PINTO1, Pamela Munguía-Realpozo1, Ivet Etchegaray-Morales2, Mario García-Carrasco2, Paulina Cortés-Hernández1, Roberto Arreguín-Reyes1, Jorge Ayón-Aguilar1 and Gabriel Rodríguez-Castillo2, 1Instituto Mexicano del Seguro Socia, Puebla, Mexico, 2Medicine School, Benemérita Universidad Autónoma de Puebla, Puebla, Mexico

    Background/Purpose: Patients with polymyositis and dermatomyositis (PM/DM) present multiple complications that may lead to increased mortality rates and data on PM/DM mortality in Mexico is…
  • Abstract Number: 2003 • ACR Convergence 2023

    Effects of Abaloparatide on Cortical and Trabecular Compartments by 3D-DXA in Men with Osteoporosis

    Ruban Dhaliwal1, John Boxberger2, Yamei Wang2, Bruce Mitlak2, Ludovic Humbert3 and Neil Binkley4, 1Massachusetts General Hospital, Boston, MA, 2Radius Health, Inc., Boston, MA, 33D-Shaper Medical, Barcelona, Spain, 4University of Wisconsin Osteoporosis Clinical Research Program, Madison, WI

    Background/Purpose: Abaloparatide (ABL) increases BMD in men with osteoporosis. In the Abaloparatide for the Treatment of Men with Osteoporosis (ATOM) trial, DXA-measured BMD change with…
  • Abstract Number: 1922 • ACR Convergence 2023

    Use of Plasma with High Titer Neutralizing Autoantibodies to Type I Interferons in Patients with Severe Refractory Flare-up of Hidradenitis Suppurativa as Novel Passive Immunotherapy Approach: Trial Protocol

    Charline Vauchy1, Maxime Desmarets1, Paul Bastard2, Anne Puel2, Pascale Richard3, Jean Laurent Casanova2, Pierre Tiberghien3, Eric Toussirot4 and Francois Aubin5, 1INSERM CIC-1431, Besançon, France, 2IHU Imagine, AP-HP Necker, Paris, France, 3Etablissement Français du Sang, St. Denis, France, 4University Hospital of Besancon, Besançon, France, 5Dermatology, University Hospital of Besancon, Besançon, France

    Background/Purpose: Hidradenitis suppurativa (HS) is a multifactorial auto-inflammatory disorder with a prevalence of 1% in North American and European populations. HS may be associated with…
  • Abstract Number: 1970 • ACR Convergence 2023

    Impaired Health-Related Quality of Life in Patients with Idiopathic Inflammatory Myopathies: A Cross-Sectional Analysis from the COVAD Dataset

    Akira Yoshida1, Yuan Li2, Vahed Maroufy2, Masataka Kuwana1, Naveen R3, Ashima Makol4, Parikshit Sen5, James Lilleker6, Vishwesh Agarwal7, Sinan Kardes8, Jessica Day9, Marcin Milchert10, Mrudula Joshi11, Tamer A Gheita12, Babur Salim13, Tsvetelina Velikova14, Abraham Edgar Gracia-Ramos15, Ioannis Parodis16, Elena Nikiphorou17, Ai Lyn Tan18, Arvind Nune19, Lorenzo Cavagna20, Miguel Angel Saavedra Salinas21, Samuel Shinjo22, Nelly Ziade23, Johannes Knitza24, Oliver Distler25, Hector Chinoy26, Vikas Agarwal3, Rohit Aggarwal27, Latika Gupta28 and COVAD Study Group29, 1Nippon Medical School Graduate School of Medicine, Tokyo, Japan, 2University of Texas Health Science Center at Houston, Houston, TX, 3Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, India, 4Mayo Clinic, Rochester, MN, Rochester, MN, 5Maulana Azad Medical College, 2-Bahadurshah Zafar Marg, New Delhi, Delhi-110002, India., Dalhi, India, 6Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK; Manchester Centre for Clinical Neurosciences, Salford Royal NHS Foundation Trust, Salford, UK. Orcid ID: 0000-0002-9230-4137., Manchester, United Kingdom, 7Mahatma Gandhi Missions Medical College, Lucknow, India, 8Istanbul University, Istanbul, Turkey, 9Walter and Eliza Hall Institute, Melbourne, Australia, 10Department of Internal Medicine, Rheumatology, Diabetology, Geriatrics and Clinical Immunology, Pomeranian Medical University in Szczecin, Szczecin, Poland, 11Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India, 12Kasr Al Ainy School of Medicine, Cairo University, Cairo, Egypt, 13Fauji foundation hospital Rawalpindi, Rawalpindi, Pakistan, 14Department of Clinical Immunology, Medical Faculty, University Hospital "Lozenetz", Sofia University St. Kliment Ohridski, Sofia, Bulgaria, 15Department of Internal Medicine, General Hospital, National Medical Center "La Raza", Instituto Mexicano del Seguro Social, Av. Jacaranda S/N, Col. La Raza, Del. Azcapotzalco, C.P. 02990, Mexico City, Mexico, 16Karolinska Institutet, Stockholm, Sweden, 17King's College London, London, United Kingdom, 18University of Leeds, Leeds, United Kingdom, 19Southport & Ormskirk NHS Foundation Trust, Liverpool, United Kingdom, 20Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, 21IMSS, Mexico City, Mexico, 22Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil, 23Saint-Joseph University, Beirut, Lebanon, 24Department of Internal Medicine 3 Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, University Hospital Erlangen, Erlangen, Germany, 25Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 26The University of Manchester, Sale, United Kingdom, 27University of Pittsburgh, Pittsburgh, PA, 28Royal Wolverhampton Trust, Wolverhampton/University of Manchester, United Kingdom, 29-, -

    Background/Purpose: The significance of Health-related quality of life (HRQoL) in patients with autoimmune diseases is well acknowledged. Unfortunately, there is dearth of data on the…
  • Abstract Number: 2019 • ACR Convergence 2023

    2023 EULAR Recommendations for the Management of Fatigue in People with Inflammatory Rheumatic and Musculoskeletal Diseases

    Emma Dures1, Bayram Farisogullari2, Eduardo Santos3, Anna Molto4, Caroline Feldthusen5, Claire Harris6, Corinna Elling-Audersch7, Deirdre Conolly8, Elena Elefante9, Fernando Estévez-López10, Ilaria Bini11, Jette Primdahl12, Kirsten Hoeper13, Marie Urban14, Mart van de Laar15, Marta Redondo16, Peter Böhm17, Raj Amarnani18, Rhys Hayward6, Rinie Geenen19, Simona Rednic20, Susanne Pettersson21, Tanja Thomsen22, Till Uhlig23, Valentin Ritschl24 and Pedro Machado25, 1Academic Rheumatology, Bristol Royal Infirmary; and Faculty of Health and Applied Sciences, University of the West of England, Bristol, United Kingdom, 2Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, 3Health Sciences Research Unit: Nursing (UICISA: E), Nursing School of Coimbra (ESEnfC), Coimbra, Portugal, 4HOPITAL COCHIN AP-HP, Service de Rhumatologie, Paris, France, 5Institute of Neuroscience and Physiology, University of Gothenburg, Department of Health and Rehabilitation, Unit of Physiotherapy, Sahlgrenska Academy, Gothenburg, Sweden, 6Northwick Park Hospital, London North West University Healthcare NHS Trust, Department of Rheumatology, London, United Kingdom, 7Deutsche Rheuma-Liga Bundesverband e.V., Patient Research Partner, Bonn, Germany, 8School of Medicine, Trinity College Dublin, Discipline of Occupational Therapy, Dublin, Ireland, 9Rheumatology Unit, Department of clinical and experimental medicine, University of Pisa, Pisa, Italy, 10Harvard T.H. Chan School of Public Health, Department of Social and Behavioral Sciences, Boston, MA, 11Anmar, Young, Rome, Italy, Rome, Italy, 12University Hospital of Southern Denmark, Danish Hospital for Rheumatic Diseases, Sønderborg, Denmark, 13Hannover Medical School, Department of Rheumatology and Immunology, Hannover, Germany, 14University Hospitals Bristol, Research Design Service, Bristol, United Kingdom, 15University of Twente, Department of Psychology, Health and Technology, Enschede, Netherlands, 16Camilo José Cela University, Faculty of Heath Sciences, Madrid, Spain, 17German League against rheumatism, Forschungspartner, Bonn, Germany, 18Barts Health NHS Trust, Barts Health Rheumatology Service, London, United Kingdom, 19Utrecht University, Vorstenbosch, Netherlands, 20Prof Dr Simona Rednic, Cluj, Romania, 21Karolinska Institute, Division of Rheumatology, Department of Medicine Solna, Stockholm, Sweden, 22University of Copenhagen, Copenhagen Centre for Arthritis Research, Centre for Rheumatology and Spine Diseases VRR, Rigshospitalet, Copenhagen, Denmark, 23Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, 24Medical University of Vienna, Vienna, Austria, 25Centre for Rheumatology & Department of Neuromuscular Diseases, University College London, London, UK. Department of Rheumatology, Northwick Park Hospital, London North West University Healthcare NHS trust, London, UK., London, United Kingdom

    Background/Purpose: Fatigue is prevalent in people with inflammatory rheumatic and musculoskeletal diseases (I-RMDs) and recognized as one of the most challenging symptoms to manage (1).…
  • Abstract Number: 1959 • ACR Convergence 2023

    Quantitative Scoring of High Resolution Chest Computed Tomography (HRCT) Images in Myositis and Antisynthetase Syndrome Related Interstitial Lung Disease in Comparison to Scleroderma Related Interstitial Lung Disease

    Sangmee Bae1, Fereidoun Abtin2, Grace Kim3, Siamak Moghadam-Kia4, Chester V. Oddis5, Lila Pourzand2, Didem Saygin5, Daniel Sullivan6, Koichi Yamaguchi7, Donald Tashkin3, Christina Charles-Schoeman8, Jonathan Goldin3 and Rohit Aggarwal5, 1UCLA Rheumatology, Los Angeles, CA, 2UCLA Radiological Sciences, Los Angeles, CA, 3University of California Los Angeles, Los Angeles, CA, 4University of Pittsburgh Medical Center, Pittsburgh, PA, 5University of Pittsburgh, Pittsburgh, PA, 6UCLA Pulmonology, Pittsburgh, PA, 7University of Pittsburgh Medical Center Rheumatology, Pittsburgh, PA, 8UCLA Medical Center, Santa Monica, CA

    Background/Purpose: High resolution computed tomography (HRCT) of the chest has become an important modality in the evaluation of interstitial lung disease (ILD). A quantitative CT…
  • Abstract Number: 1434 • ACR Convergence 2023

    Long-Term Efficacy and Safety of Risankizumab for Active Psoriatic Arthritis: 148-Week Results from the KEEPsAKE 2 Trial

    Andrew Östör1, Filip Van den Bosch2, Kim A Papp3, Cecilia Asnal4, Ricardo Blanco5, Jacob Aelion6, Vassilis Stakias7, Thomas Iyile7, Kyle Carter7, Ahmed Soliman7, Leonidas Drogaris7, Michael Chen7, Byron Padilla7 and Alan Kivitz8, 1Monash University & Emeritus Research; Australian National University, Melbourne, Australia, 2Department of Internal Medicine and Pediatrics, Ghent University and VIB Center for Inflammation Research, Ghent, Belgium, 3Alliance Clinical Research and Probity Medical Research, Waterloo, and University of Toronto, Toronto, ON, Canada, 4Hospital Alemán, Buenos Aires, Argentina, 5Rheumatology Department, Immunopathology Group, Hospital Universitario Marqués de Valdecilla-IDIVAL, Santander, Spain, 6West Tennessee Research Institute, Jackson, TN, 7AbbVie, Inc., North Chicago, IL, 8Altoona Center for Clinical Research, Duncansville, PA

    Background/Purpose: PsA is a chronic systemic inflammatory disease that affects 30% of patients diagnosed with psoriasis, with a clinical burden that includes dactylitis, enthesitis, cutaneous…
  • Abstract Number: 2005 • ACR Convergence 2023

    Secondary Prevention of Osteoporosis in Hip Fracture Care for Elderly Patients. Clinical and Functional Profile of Users

    Belén Miguel Ibáñez, Alfonso González Ramírez, Olga Martínez González, Ana Isabel Turrión Nieves, Marta Ibáñez Martínez, Carolina Cristina Chacón Vélez, Laura Blanco Ramis, Manuel Cipriano Martín Martínez, Cristina Hidalgo Calleja, Carlos Alberto Montilla Morales, Susana Gómez Castro, Juan Francisco Blanco Blanco and Carmen Pablos Hernández, University Healthcare Complex of Salamanca, Salamanca, Spain

    Background/Purpose: Osteoporosis is a first-rate problem in an increasingly ageing population. Falls among the elderly are a severe geriatric syndrome with relevant secondary effects. Fractures…
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