ACR Meeting Abstracts

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  • Abstract Number: 1519 • ACR Convergence 2023

    Renal Complications Following Autologous Stem Cell Transplantation for Systemic Sclerosis

    Malcolm MacKenzie1, Harry Atkins2 and Nancy Maltez1, 1The Ottawa Hospital, Ottawa, ON, Canada, 2Ottawa Hospital Research Institute, Ottawa, ON, Canada

    Background/Purpose: Rapidly progressive diffuse systemic sclerosis (SSc) is a devastating autoimmune disease with high morbidity and mortality. Autologous hematopoietic stem cell transplantation (AHSCT) is recognized…
  • Abstract Number: 1637 • ACR Convergence 2023

    IgG-Fc-N-Sialylation and -Galactosylation in Primary Sjögren’s Syndrome (Pss) in Its Potential as Marker of Disease State and Disease Activity

    Helena Achten1, Liselotte Deroo2, Kristel De Boeck3, Matthias Jarlborg1, Tine Decruy1, Joke Deprez1, Emilie Dumas1, Dirk Elewaut4 and isabelle peene5, 1Ghent University, Ghent, Belgium, 2Ghent University, Gent, Belgium, 3Ghent University Hospital, Ghent, Belgium, 4Ghent University and VIB Center for Inflammation Research, Ghent, Belgium, 5University Hospital Ghent, Ghent, Belgium

    Background/Purpose: Loss of galactose and sialic acid structures attached to the IgG-Fc-fragment switches the antibody effector function from anti-inflammatory to pro-inflammatory1. This study investigated the…
  • Abstract Number: 1621 • ACR Convergence 2023

    Maxillofacial MRI Augments Detection of Non-CNS Abnormalities in Pediatric Craniofacial Scleroderma

    Daniel Glaser1, Amy Metry2, Elena DeRosas2, Subramanian Subramanian2 and Kathryn Torok3, 1Yale University School of Medicine, New Haven, CT, 2University of Pittsburgh, Pittsburgh, PA, 3University of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA

    Background/Purpose: Craniofacial scleroderma is a rare subtype of linear scleroderma affecting the head and neck. Up to 40% of patients experience extracutaneous manifestations (ECMs), but…
  • Abstract Number: 1646 • ACR Convergence 2023

    The Real-World Experience of Combined Cranial and Large Vessel FDG-PET/CT in the Investigation of Giant Cell Arteritis

    Keren Port1, Ivan Ho Shon1, Sally Ayesa1, Rachel Langford1, Olivia Bennett1, Andrew Csillag1, Stacey Fredericks1, Luz Palacios-Derflingher2, Eva Wegner1 and Anthony Sammel1, 1The Prince of Wales Hospital, Sydney, Australia, 2University of New South Wales, Sydney, Australia

    Background/Purpose: GCA is a systemic medium-large vessel vasculitis (M-LVV) involving the cranial arteries, aorta and its major branches. Recent studies have shown that PET/CT including…
  • Abstract Number: 1221 • ACR Convergence 2023

    Familial Clustering of Dysbiotic Oral and Fecal Microbiomes in Juvenile Dermatomyositis (JDM)

    Albert Chow1, Sean Koester2, Evan Pepper-Tunick3, Peggy Lee4, Mary Eckert5, Laurie Brenchley6, Pamela Gardner6, Naisi Li2, adam Schiffenbauer7, Rita Volochayev7, Nastaran Bayat8, Jeffrey McLean9, Lisa Rider10, Susan Shenoi11, Anne Stevens12 and Neelendu Dey13, 1Loma Linda University, Loma Linda, CA, 2Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA, 3Molecular Engineering & Sciences Institute, University of Washington, Seattle, WA, 4Department of Oral Medicine, School of Dentistry, University of Washington, Seattle, WA, 5Center for Clinical and Translational Research, Seattle Children’s Research Institute, Seattle, WA, 6Office of the Clinical Director, NIDCR, National Institutes of Health, Bethesda, MD, 7Environmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, MD, 8Social Scientific Systems, DLH Holdings Corp, Silver Spring, MD, 9Department of Periodontics, University of Washington, Seattle, WA, 10NIEHS, NIH, Bethesda, MD, 11Seattle Childrens Hospital, Mercer Island, WA, 12Janssen, Hansville, WA, 13Department of Medicine, Division of Gastroenterology, University of Washington, Seattle, WA

    Background/Purpose: JDM is a rare immune-mediated disease of childhood that is thought to result from genetic predisposition and environmental drivers, with documented links to microbial…
  • Abstract Number: 1645 • ACR Convergence 2023

    Aortic Dilatation and PET/CT Vascular Activity at Diagnosis and 5 Years in an Inception Giant Cell Arteritis (GCA) Cohort

    Anthony Sammel1, Ivan Ho Shon2, Daniel Moses1, Fredericks Stacey1, Gita Mathur1, Claudia Hillenbrand3, Edward Hsiao4, Schembri Geoffrey4, Rodger Laurent4 and Eva Wegner2, 1Prince of Wales Hospital, Randwick, Australia, 2The Prince of Wales Hospital, Sydney, Australia, 3University of NSW, Randwick, Australia, 4Royal North Shore Hospital, St. Leonards, Australia

    Background/Purpose: Aortic dilatation is typically a late complication of giant cell arteritis (GCA) but there are no tools to risk stratify patients at the time…
  • Abstract Number: 1617 • ACR Convergence 2023

    Comparing Uptake of Biosimilar Infliximab Among Patients with Medicare, Medicaid and Private Insurance in U.S. Rheumatology Practices 2016-2022

    Eric Roberts1, Jing Li1, Nick Bansback2, Chien-Wen Tseng3, Steve Shiboski1, Gabriela Schmajuk4 and Jinoos Yazdany1, 1University of California San Francisco, San Francisco, CA, 2University of British Columbia, Vancouver, BC, Canada, 3University of Hawai'i John A. Burns School of Medicine, Honolulu, HI, 4UCSF / SFVA, San Francisco, CA

    Background/Purpose: The first infliximab biosimilar (infliximab-dybb) entered the U.S. market in 2016, and two additional products have subsequently been introduced (infliximab-axxq (2017) and infliximab-abda (2020)).…
  • Abstract Number: 1657 • ACR Convergence 2023

    Mapping the Network of Coordinated Immune Dysregulation in Juvenile Dermatomyositis at Single-cell Resolution

    Gabrielle Rabadam1, Camilla Wibrand2, Emily Flynn1, George Hartoularos1, Yang Sun1, Susan Kim3, Chun Jimmie Ye1, Zev Gartner1, Marina Sirota4 and Jessica Neely1, 1University of California San Francisco, San Francisco, CA, 2Aarhus University, Aarhus, Denmark, and University of California San Francisco, San Francisco, CA, 3UCSF Benioff Children's Hospital, San Francisco, CA, 4Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA

    Background/Purpose: Juvenile Dermatomyositis (JDM) is a rare multisystem autoimmune condition that involves complex immune responses in both innate and adaptive compartments. Currently, we have a…
  • Abstract Number: 1246 • ACR Convergence 2023

    Assessment and Outcomes of 63 Cases of Juvenile Dermatomyositis-Associated Calcinosis

    Belina Yi1, Dawn Wahezi2, Lauren Covert3, Kaveh Ardalan4, Joyce Hui-Yuen5, Natalia Vasquez Canizares6, Doaa Mosad Mosa7, Madison Jones8, Colleen Correll9, Alexis Begezda10, Susan Shenoi11, Eveline Wu12, Leonard Kovalick13, William Lapin14, Stacey Tarvin15, Melissa Oliver16, Martha Rodriguez17, Itay Marmor18, Kevin Baszis19, Alysha Taxter20, Andrew Hanson21, Cynthia Crowson22 and Amir Orandi22, 1Children's Hospital Los Angeles, Los Angeles, CA, 2Children's Hospital at Montefiore, New Rochelle, NY, 3Duke University, Durham, NC, 4Duke University School of Medicine, Durham, NC, 5North Shore LIJ Health System, Great Neck, NY, 6Children's Hospital at Montefiore, New York, NY, 7Mansoura University Hospitals, Mansoura University Faculty of Medicine, Mansoura city, Egypt, 8Keck School of Medicine of University of Southern California, Los Angeles, CA, 9University of Minnesota, Minneapolis, MN, 10Penn State, Hummelstown, PA, 11Seattle Childrens Hospital, Mercer Island, WA, 12University of North Carolina School of Medicine, Chapel Hill, NC, 13UNC Health Care, Durham, NC, 14Connecticut Children's, Hartford, CT, 15Riley Hospital for Children at Indiana University Health, Indianapolis, IN, 16Indiana University, Indianapolis, IN, 17Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN, 18Dana-Dwek Children's Hospital, Hod Hasharon, Israel, 19Washington Univ in St. Louis School of Medicine, St. Louis, MO, 20Nationwide Children's, Columbus, OH, 21Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, 22Mayo Clinic, Rochester, MN

    Background/Purpose: Calcinosis is a poorly understood and morbid complication of juvenile dermatomyositis (JDM). As there is no consensus treatment approach for calcinosis, and limited knowledge…
  • Abstract Number: 1223 • ACR Convergence 2023

    Extracorporeal Life Support for Childhood-Onset Systemic Lupus Erythematosus: An ELSO Registry Analysis

    Carla Levin1, Andrea Ontaneda2, Danielle Guffey3, Peter Rycus4, Marc Anders2, Eyal Muscal5 and Maria Pereira5, 1Department of Pediatrics, Baylor College of Medicine, Houston, TX, 2Division of Critical Care, Department of Pediatrics, Baylor College of Medicine, Houston, TX, 3Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, TX, 4Extracorporeal Life Support Organization, Ann Arbor, MI, 5Division of Rheumatology, Department of Pediatrics, Baylor College of Medicine, Houston, TX

    Background/Purpose: Systemic Lupus Erythematosus (SLE) is a heterogeneous multisystemic autoimmune disorder that can cause life-threatening complications. There is a paucity of data on the utility…
  • Abstract Number: 1629 • ACR Convergence 2023

    Persons with Rheumatoid Arthritis and Long COVID Had Worse Pre-COVID RA Symptoms and Worse Non-RA Symptoms, as Well as Higher Rates of Fibromyalgia Compared with COVID Infected Long COVID Negative

    Kaleb Michaud1, Sofia Pedro2, Shreena Kamlesh Gandhi3 and Frederick Wolfe2, 1University of Nebraska Medical Center, Omaha, NE, 2Forward, The National Databank for Rheumatic Diseases, Wichita, KS, 3Kansas University School of Medicine, Wichita, KS

    Background/Purpose: Long COVID, also known as Post COVID syndrome or postacute sequelae of SARS-CoV-2 infection, refers to the development of persistent or new symptoms lasting…
  • Abstract Number: 1552 • ACR Convergence 2023

    Epidemiology and Outcome of Eosinophilic Granulomatosis with Polyangiitis in France

    Benjamin Terrier1, Camille Taillé2, Alice Brouquet3, Solenne Tauty3, Francoise Bugnard3, Loic Guillevin4, Xavier Puéchal5 and Vincent Cottin6, 1Department of Internal Medicine, Hôpital Cochin, AP-HP, Paris, France, 2AP-HP, Bichat Hospital, Reference Center for Rare Pulmonary Diseases and University of Paris Cité, Inserm 1152, Paris, France, 3Steve Consultant, Lyon, France, 4University Paris Descartes, Paris, France, 5National Referral Center for Rare Systemic Autoimmune Diseases, Paris, France, 6Coordinating Reference Center for Rare Pulmonary Diseases, Louis Pradel Hospital, University of Lyon, INRAE, Lyon, France

    Background/Purpose: Eosinophilic granulomatosis with polyangiitis (EGPA, formerly Churg-Strauss) belongs to the group of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV). There are no recent data on…
  • Abstract Number: 1419 • ACR Convergence 2023

    Impact of Psoriatic Arthritis Manifestations on Perception of Pain Improvement: Pooled Analysis of Two Phase 3, Randomized, Double-Blind, Placebo-Controlled Studies with Guselkumab

    Peter Nash1, Iain McInnes2, Christopher T. Ritchlin3, Lai-Shan Tam4, Enrique Soriano5, Michael Starr6, Emmanouil Rampakakis7, Frederic Lavie8, May Shawi9, Xenofon Baraliakos10 and Philip J. Mease11, 1School of Medicine, Griffith University, Brisbane, Australia, 2University of Glasgow, Glasgow, United Kingdom, 3University of Rochester Medical Center, Department of Medicine – Allergy/Immunology and Rheumatology, Rochester, NY, 4The Chinese University of Hong Kong, New Territories, China, 5Rheumatology Section, Internal Medicine Services, Hospital Italiano de Buenos Aires, and University Institute Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 6Division of Rheumatology, McGill University Health Center, Montreal, QC, Canada, 7McGill University, Department of Pediatrics / JSS Medical Research, Scientific Affairs, Montreal, QC, Canada, 8The Janssen Pharmaceutical Companies of Johnson & Johnson, Paris, France, 9Immunology, Janssen Research & Development, LLC, Titusville, NJ, 10Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 11Swedish Medical Center/Providence St. Joseph Health and University of Washington School of Medicine, Seattle, WA

    Background/Purpose: Pain in PsA has multifaceted origins (e.g., peripheral joint inflammation, axial involvement [axPsA], skin lesions, dactylitis, enthesitis, underlying conditions) and can be difficult to…
  • Abstract Number: 1209 • ACR Convergence 2023

    The Role of Kinesiophobia on Ankylosing Spondylitis Disease Activity, Exercise Habits, and Quality of Life

    Joel Thompson, University of North Carolina at Chapel Hill, Chapel Hill, NC

    Background/Purpose: Patients with Ankylosing Spondylitis (AS) consistently report exercise frequencies that are lower than healthy controls and ACSM/EULAR recommended frequencies; even though exercise has consistently…
  • Abstract Number: 1735 • ACR Convergence 2023

    An Unorthodox HLA-DRhiCD15+ ‘Hybrid’ Population in Rheumatoid Arthritis Characterized Using Spectral Cytometry

    Christian Geier1, Haani Qudsi2, Jihad BenGabr1, Robert Winchester3 and Andras Perl4, 1SUNY Upstate Medical University, Syracuse, NY, 2Norton College of Medicine, SUNY Upstate Medical University, Syracuse, NY, 3Columbia University, New York, NY, 4SUNY, Syracuse, NY

    Background/Purpose: A variant of HLA-DR confers the strongest genetic risk for rheumatoid arthritis (RA) suggesting that DRhi cells are important in RA. We previously found…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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