ACR Meeting Abstracts

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  • Abstract Number: 026 • 2026 Pediatric Rheumatology Symposium

    Treatment strategies for articular flares in JIA patients receiving biologic therapy

    Jonatan zalcman, Yoel Levinsky, Liora Harel, Ruth Livny and gil amarilyo, Schneider Children's medical center of Israel

    Background/Purpose: Biologic agents form the cornerstone of therapy for Juvenile Idiopathic Arthritis (JIA); however, the optimal management of flares that occur during ongoing treatment remains…
  • Abstract Number: 005 • 2026 Pediatric Rheumatology Symposium

    Magnetic Resonance Enterography Detected Sacroiliitis in Pediatric Crohn’s Disease: A Retrospective Cohort Study

    Aaisham Ali1, Vishal Kalia2, Ian Ross2, Luke Daichendt3, Julia Sawicka4, Michael R Miller5, Sarah Wells6, Eileen Crowley6 and Roberta A Berard7, 1Schulich School of Medicine & Dentistry, Pediatrics, London Health Sciences Centre, London, ON, Canada, 2Department of Medical Imaging, Western University, 3Schulich School of Medicine & Dentistry, Western University, 4Western University, 5Department of Pediatrics, Children's Hospital, London Health Sciences Centre, 6London Children's Hospital, ON, Canada, 7London Health Sciences Centre, London, ON, Canada

    Background/Purpose: Musculoskeletal (MSK) manifestations are amongst the most common extraintestinal manifestations (EIMs) in pediatric Crohn’s disease (CD). MSK EIMs contribute to reduced quality of life…
  • Abstract Number: 010 • 2026 Pediatric Rheumatology Symposium

    Efficacy and Safety of Emapalumab in Patients with Macrophage Activation Syndrome (MAS) in Systemic Lupus Erythematosus (SLE)

    Alexei Grom1, Shoghik Akoghlanian2, melissa elder3, Renee Modica4, Steve Mallett5, Brian D. Jamieson6 and Fabrizio De Benedetti7, 1Cincinnati Children’s Hospital, Division of Rheumatology, Cincinnati, OH, 2Nationwide Childrens Hospital, Columbus, OH, 3Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, University of Florida, GAINESVILLE, FL, 4Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, University of Florida, Orlando, FL, 5Sobi, 6Sobi, Inc., 7Bambino Gesu Children's Hospital, Rome, Rome, Italy

    Background/Purpose: MAS is a life-threatening complication of SLE, characterized by interferon-gamma (IFNg)-driven macrophage activation and systemic hyperinflammation. There is substantial preclinical evidence of IFNg having…
  • Abstract Number: 002 • 2026 Pediatric Rheumatology Symposium

    Assessing Juvenile Idiopathic Arthritis Healthcare Costs to Advance Value-Based Care

    Julia Harris1, Luke Harris2, Kristy Diederich3, Rachel Moran3, Emily Fox2, Leslie Favier4, Stephanie Quinn3 and ashley cooper2, 1Children's Mercy Kansas City, Overland Park, KS, 2Children's Mercy Kansas City, Kansas City, MO, 3Children's Mercy Kansas City, 4Children's Mercy Kansas City, Leawood, KS

    Background/Purpose: Despite treatment advances and continued quality improvement efforts, outcomes for our patients with juvenile idiopathic arthritis (JIA) remain suboptimal. To address this challenge, we…
  • Abstract Number: 012 • 2026 Pediatric Rheumatology Symposium

    Prevalence and Impact of Adverse Childhood Experiences in Pediatric Systemic Lupus Erythematosus

    Anita Dhanrajani1, Rhea Bhargava2 and Alfred Kim3, 1Manning Family Children's Hospital, Tulane University, 2Tulane University Medicine, New Orleans, LA, 3Washington University School of Medicine, Saint Louis, MO

    Background/Purpose: Adverse childhood experiences (ACEs) have been linked to incident childhood-onset SLE (cSLE) and poorer patient-reported outcomes, raising the possibility that early-life stress may contribute…
  • Abstract Number: 016 • 2026 Pediatric Rheumatology Symposium

    Still’s Disease Associated Lung Disease: Experience from a Tertiary Italian Centre

    Claudia Bracaglia1, Manuela Pardeo2, Matteo Trevisan2, Arianna De Matteis2, Ivan Caiello3, Giusi Prencipe3 and Fabrizio De Benedetti4, 1Division of Rheumatology Ospedale Pediatrico Bambino Gesu' IRCCS, Roma, Italy, Rome, Rome, Italy, 2Division of Rheumatology, Ospedale Pediatrico Bambino Gesù IRCCS, Roma, Italy, Rome, Lazio, Italy, 3Laboratory of Immuno-Rheumatology, Ospedale Pediatrico Bambino Gesù IRCCS, Roma, Italy, Rome, Lazio, Italy, 4Bambino Gesu Children's Hospital, Rome, Rome, Italy

    Background/Purpose: Still’s Disease (SD)-associated lung disease (SD-LD) is a severe potentially life-threatening condition characterized by peculiar features. For the rarity of this condition, the experience…
  • Abstract Number: 043 • 2026 Pediatric Rheumatology Symposium

    Challenges of Cognitive Screening and Formal Neuropsychological Evaluation in Youth with Childhood-Onset Systemic Lupus Erythematosus: A Survey of CARRA Providers

    Ryan Kammeyer1, Martha Rodriguez2, Andrea Knight3, Rebecca Sadun4, Jeffrey Bennett5, Robert Fuhlbrigge6, Christa Hutaff-Lee5 and Ekemini Ogbu7, 1Departments of Pediatrics and Neurology, University of Colorado School of Medicine, Aurora, CO, 2Riley Hospital For Children At Indiana University, Carmel, IN, 3Hospital for Sick Children, Toronto, ON, Canada, 4Duke University School of Medicine, Durham, NC, 5University of Colorado School of Medicine, 6University of Colorado, Aurora, CO, 7Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose: Cognitive dysfunction (CD) occurs in 30-60% of youth with childhood-onset systemic lupus erythematosus (cSLE), and negatively impacts medical care, socioeconomic achievement, and quality of…
  • Abstract Number: 003 • 2026 Pediatric Rheumatology Symposium

    Dysregulated Macrophage–Fibroblast Crosstalk Identified by Single-Cell RNA-seq in Juvenile Systemic Scleroderma Skin

    Aneri Shethji1, Theresa Hutchins1, Anwesha Sanyal1 and Kathryn Torok2, 1UPMC Childrens Hospital of Pittsburgh, 2University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Juvenile systemic scleroderma (jSSc) is a rare autoimmune disease characterized by progressive fibrosis and vascular dysfunction. Although jSSc shares important clinical features with adult…
  • Abstract Number: 042 • 2026 Pediatric Rheumatology Symposium

    Mindfulness Matters: Early Insights from the Making Mindfulness Matter© in children with Juvenile Idiopathic Arthritis Study.

    Roberta A Berard1, KAREN BEATTIE2, Sarah Wells3, Michelle Batthish4, Asha Jeyanathan5, Frances Montemurro6, Karen Bax7 and Andrea Knight8, 1London Health Sciences Centre, London, ON, Canada, 2McMaster University, Hamilton, ON, Canada, 3London Children's Hospital, ON, Canada, 4McMaster Children's Hospital, Hamilton, ON, Canada, 5Hospital for Sick Children, ON, Canada, 6The Hospital for Sick Children, Toronto, ON, Canada, 7Adjunct Professor, Psychology, Western Ontario, ON, Canada, 8Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: Poor mental health (MH) in the pediatric rheumatology population has been shown to affect quality of life, educational attainment, and disease-related outcomes, such as…
  • Abstract Number: 025 • 2026 Pediatric Rheumatology Symposium

    Longitudinal Single Cell Transcriptomic Analysis of Type I and II Interferon (IFN) Response Genes (IRG) in Refractory Juvenile Dermatomyositis (JDM) Patients with Baricitinib Treatment

    Jessica Simpson1, Vicky Chen2, Adeline Chin3, Ujana Zajmi3, Amy Kaneshiro3, Megan Darrell4, Stephen Brooks3, Robert Colbert5, Lisa Rider6, Stefania Dell’Orso3, Faiza Naz3 and Hanna Kim7, 1National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)/National Institutes of Health (NIH), 2National Institute of Allergy and Infectious Diseases (NIAID)/ National Institutes of Health (NIH), Frederick, MD, 3National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) / National Institutes of Health (NIH), 4National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) / National Institutes of Health (NIH), NY, 5National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) / National Institutes of Health (NIH), Rockville, MD, 6National Institute of Environmental Health Sciences (NIEHS)/National Institutes of Health (NIH), 7National Institute of Arthritis Musculoskeletal and Skin Diseases (NIAMS) / National Institutes of Health (NIH)

    Background/Purpose: JDM is a rare heterogenous autoimmune condition. Pathogenesis is incompletely understood, though dysregulated type I/II IFN signaling is well-documented. Patients with refractory JDM had…
  • Abstract Number: 006 • 2026 Pediatric Rheumatology Symposium

    Age Matters: Clinical Profile and IVIG Responsiveness in infants with Kawasaki Disease. A multicentric retrospective analysis of 36 patients from North India

    Abhay Shivpuri1, manjari Agarwal2 and sujata Sawhney3, 1Neoclinic Children's Hospital, Jaipur, Rajasthan, India, 2Sir Ganga Ram Hospital, NEW DELHI, Delhi, India, 3Sir Ganga Ram Hospital, Sector 37 noida, Uttar Pradesh, India

    Background/Purpose: Kawasaki disease (KD) is a systemic medium vessel vasculitis that is predominantly a clinical diagnosis as defined by the American Heart Association (AHA). KD…
  • Abstract Number: 028 • 2026 Pediatric Rheumatology Symposium

    Are You Positive About this Positive ANA Referral? Outcomes for ANA Based Referrals to Pediatric Rheumatology and Subsequent Disease Development

    Josh Umland1, Elizabeth Volkmann2, Annabelle Lee3, Nicholas Jackson2, Deborah McCurdy4, Alice Hoftman5, Miriam Parsa6, John Fitzgerald7 and Alexis Stephens8, 1UCLA, 2University of California, Los Angeles, Los Angeles, CA, 3UCLA Department of Medicine Statistics Core, San Diego, CA, 4UCLA Medical Center, Los Angeles, CA, 5David Geffen School of Medicine, UCLA, Los Angeles, CA, 6Cottage Childrens Medical Center, SANTA BARBARA, CA, 7UCLA, Los Angeles, CA, 8University of California, Los Angeles

    Background/Purpose: ANA positivity is a frequent finding in pediatric rheumatology referrals, but infrequently reflects underlying autoimmune disease. Earlier studies found that most ANA positive patients…
  • Abstract Number: 041 • 2026 Pediatric Rheumatology Symposium

    Pediatric Behçet’s Disease: A 13-Year Single-Center Experience Highlighting Diagnostic Delays and High Neurological Burden

    Rasha Elrefai1, Andrea Ramirez1, Jamie Lai2, Cagri Yildirim-Toruner3, Eyal Muscal1 and Marietta DeGuzman1, 1Baylor College of Medicine, Houston, TX, 2Baylor College of Medicine, The Woodlands, TX, 3Texas Children's Hospital/ Baylor College of Medicine, Houston, TX

    Background/Purpose: Behçet's disease (BD) is a systemic vasculitis primarily characterized by recurrent oral and genital aphthous ulceration. It is reported that 15-20% of all BD…
  • Abstract Number: 034 • 2026 Pediatric Rheumatology Symposium

    Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Management Across Countries: A Survey to Inform Future Comparative Effectiveness Research

    Mehmet YILDIZ1, Samira Nazzar Romero2, Lakshmi Moorthy3, Edan Itzkovitz4, Halide Ozge Basaran5, Tara Lozy6, Patricia DeLaMora7, Tatjana Welzel8, Ruby Haviv9, Kalpana Manthiram10, Camilo Vargas11, Erdal Sag12, amit ziv13, Adi Pappo14, Özlem Satirer15, Maryam Piram16, Gülşah Kavrul Kayaalp17, Nuray Aktay Ayaz18, Antonella Insalaco19, Jasmin Kuemmerle-Deschner20, Dilan Dissanayake4, Kader Cetin Gedik21, Nadine Saad22, Nataša Toplak23, Ozgur Kasapcopur24, Marinka Twilt25, Isabelle koné-Paut26, Ronald M. Laxer27, Marco Gattorno28, Seza zen29, Fatma Dedeoglu30 and Sivia Lapidus31, 1Division of Pediatric Rheumatology, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Turkey, Istanbul, Turkey, 2Division of Rheumatology, Nemours Children's Health, University of Central Florida College of Medicine, Orlando, United States, Orlando, FL, 3Department of Pediatrics, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, United States, Metuchen, NJ, 4Division of Rheumatology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Canada, Toronto, ON, Canada, 5Department of Pediatrics, Hacettepe University, Ankara, Türkiye, New York City, NY, 6Joseph M. Sanzari Children's Hospital, Hackensack Meridian Health, Center for Discovery and Innovation, Hackensack Meridian Health and Hackensack Meridian School of Medicine, 7Department of Pediatrics, School of Medicine, New York Medical College, Valhalla, United States, 8Pediatric Rheumatology, University Children's Hospital Basel (UKBB), University of Basel, Basel, Switzerland, 9Pediatric Rheumatology Unit, Department of Pediatrics, Meir Medical Center, Kfar Saba, Israel., 10Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, United States, Bethesda, MD, 11Faculty of Medicine, Universidad del Valle, Cali, Colombia, Cali, Colombia, 12Department of Pediatric Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, and Division, Ankara, Turkey, 13Pediatric Rheumatology Unit, Department of Pediatrics, Meir Medical Center, Kfar Saba, Israel, herzelia, Israel, 14Pediatric Rheumatology Unit, Schneider Children's Medical Center of Israel, Petach Tikva, Israel, HaMerkaz, Israel, 15Department of Paediatrics and Autoinflammation reference Center Tuebingen (arcT), Universitatsklinikum Tubingen, Tubingen, Baden-Württemberg, Germany, 16Department of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montreal, QC, Canada; CHU Sainte-Justine Research Center, Université de Montréal, Montreal, QC, Canada, Montral, Canada, 17Department of Pediatric Rheumatology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey, 18Department of Pediatric Rheumatology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey, Istanbul, Turkey, 19Division of Rheumatology, ERN RITA Center, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy, Rome, Italy, 20Department of Paediatrics and Autoinflammation reference Center Tuebingen (arcT), Universitatsklinikum Tubingen, Tubingen, Baden-Württemberg, Germany, Tuebingen, Germany, 21Division of Pediatric Rheumatology, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; Pediatric Autoinflammatory Diseases Center, University of Pittsburgh, Pittsburgh, United States, Pittsburgh, PA, 22University of Michigan, Michigan Medicine, Ann Arbor, Michigan, United States, Ann Arbor, MI, 23Department of Allergology, Rheumatology and Clinical Immunology, University Children's Hospital, Ljubljana, Slovenia, 24Istanbul University-Cerrahpasa, Department of Pediatric Rheumatology, Istanbul, Türkiye, istanbul, Turkey, 25Alberta Children's Hospital, Calgary, AB, Canada, 26Department of Pediatrics, Kremlin-Bicêtre University Hospital, Paris-Saclay University, Paris, France, 27The Hospital for Sick Children, Toronto, ON, Canada, 28Division of Rheumatology and Autoinflammatory Diseases, IRCCS Istituto Giannina Gaslini, Genoa, Italy, Genova, Italy, 29Hacettepe University Medical Faculty, Ankara, Turkey, 30Boston Children's Hospital, Boston, MA, 31Joseph M. Sanzari Children's Hospital, Hackensack Meridian Health, Center for Discovery and Innovation, Hackensack Meridian Health and Hackensack Meridian School of Medicine, Montclair, NJ

    Background/Purpose: Background: PFAPA is the most common autoinflammatory condition of childhood. Its frequency, clinical features, and response to treatments vary across populations. To standardize care, the…
  • Abstract Number: 021 • 2026 Pediatric Rheumatology Symposium

    Medication Changes and Lung Disease Activity in Systemic JIA: Six-Month Follow-Up of CARRA Registry SJIA-LD Cohort

    Grant Schulert1, Eileen Rife2, Mary Ellen Riordan3, Alan Russell4, Mei-Sing Ong5, Esraa Eloseily6, Lexi Auld7, Yukiko Kimura8, and CARRA Registry SJIA-LD Cohort Investigators 1Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2University of Alabama Birmingham, Vestavia Hills, AL, 3Hackensack University Medical Center, Westwood, NJ, 4Duke Clinical Research Institute, NC, 5Boston Children's Hospital, Boston, MA, 6UT Southwestern Children's Medical Center, Dallas, TX, 7Cincinnati Children's Hospital Medical Center, OH, 8Hackensack Meridian School of Medicine, New York, NY

    Background/Purpose: Lung disease is a severe and potentially fatal complication of systemic juvenile idiopathic arthritis (SJIA-LD). The Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry…
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All abstracts accepted to PRYSM are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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