Abstracts Archive - Page 259 of 2425 - ACR Meeting Abstracts

Abstract Number: 0798 • ACR Convergence 2023
A Novel 3D Model of Rheumatoid Arthritis Synovial Tissue Incorporating Fibroblasts, Endothelial Cells and Macrophages
Eva Philippon¹, Lisanne van Rooijen¹, Jan Piet van Hamburg¹, Fatemeh Khodadust¹, Conny Van der Laken² and Sander Tas³, ¹Amsterdam University Medical Centers, Amsterdam, Netherlands, ²Amsterdam UMC - location VUMC, Amsterdam, Netherlands, ³Amsterdam UMC, locatie AMC, Utrecht, Netherlands
Background/Purpose: Rheumatoid Arthritis (RA) is a progressive and systemic autoimmune disorder associated with chronic and destructive inflammation of the joints. The hallmarks of RA are…
Abstract Number: 1417 • ACR Convergence 2023
Do Long-term Patient-reported Outcomes Improve Similarly in Psoriatic Arthritis and Axial Spondyloarthritis Patients Treated with Secukinumab? Results from the EuroSpA Collaboration
Marion Pons¹, Simon Horskjær Rasmussen¹, Sara Nysom Christiansen¹, Brigitte Michelsen², Bente Glintborg¹, Bjorn Gudbjornsson³, Gerdur Maria Grondal⁴, Jiri Vencovsky⁵, Anne Gitte Loft⁶, Ziga Rotar⁷, Katja Perdan Pirkmajer⁸, Michael Nissen⁹, Burkhard Moeller¹⁰, Gary Macfarlane¹¹, Gareth T. Jones¹¹, Florenzo Iannone¹², Roberto F. Caporali¹³, Karin Laas¹⁴, Sigrid Vorobjov¹⁵, Daniela Di Giuseppe¹⁶, Belkis Nihan Coskun¹⁷, Burcu Yagız¹⁷, Sella Provan¹⁸, Karen Fagerli¹⁸, Isabel Castrejon¹⁹, Lucia Otero-Valera²⁰, Marleen van de Sande²¹, Irene van der Horst-Bruinsma²², Dan Nordstrom²³, Laura Kuusalo²⁴, Elsa Vieira-Sousa²⁵, Miguel Bernardes²⁶, Tor Olofsson²⁷, Jana Baranová²⁸, Merete Hetland¹, Mikkel Østergaard²⁹ and Lykke Ørnbjerg¹, ¹Copenhagen Center for Arthritis Research, Rigshospitalet, Copenhagen, Denmark, ²Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, ³Centre for Rheumatology Research, University Hospital, Reykjavik, Iceland, ⁴Department for Rheumatology, Landspitali University Hospital, Reykjavik, Iceland, ⁵Institute of Rheumatology, Prague, Czech Republic, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, ⁶Aarhus University, Horsens, Denmark, ⁷University Medical Centre Ljubljana, Ljubljana, Slovenia, ⁸University Medical Centre Ljubljana; University of Ljubljana, Ljubljana, Slovenia, ⁹Geneva University Hospitals, Geneva, Switzerland, ¹⁰Inselspital - University Hospital Bern, Bern, Switzerland, ¹¹Aberdeen Centre for Arthritis and Musculoskeletal Health (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ¹²Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari "Aldo Moro", Bari, Italy, ¹³Department of Clinical Sciences and Community Health, University of Milan, and Department of Rheumatology and Medical Sciences, ASST Gaetano Pini-CTO, Milano, Italy, ¹⁴Department of Rheumatology, East-Tallinn Central Hospital, Tallinn, Estonia, ¹⁵National Institute for Health Development, Tallinn, Estonia, ¹⁶Karolinska Institutet, Stockholm, Sweden, ¹⁷Department of Rheumatology, Bursa Uludag University, Bursa, Turkey, ¹⁸Diakonhjemmet Hospital, Oslo, Norway, ¹⁹Hospital Universitario Gregorio Marañón, Madrid, Spain, ²⁰Spanish Society of Rheumatology, Madrid, Spain, ²¹Amsterdam UMC, University of Amsterdam, Department of Rheumatology & Clinical Immunology and Department of Experimental Immunology, Amsterdam Infection & Immunity Institute; Amsterdam Rheumatology & Immunology Center (ARC), Academic Medical Center, Amsterdam, Netherlands, ²²Rheumatology, Radboud University Medical Center, Nijmegen, Netherlands, ²³Helsinki University Hospital, Helsinki, Finland, ²⁴Centre for Rheumatology and Clinical Immunology, University of Turku and Turku University Hospital, Turku, Finland, ²⁵Faculdade de Medicina da Universidade de Lisboa, Centro Académico de Medicina de Lisboa, Lisboa, Portugal, ²⁶Rheumatology Department, Centro Hospitalar e Universitário de São João, Porto, Portugal, ²⁷Lund University and Skåne University Hospital, Lund, Sweden, ²⁸Institute of Biostatistics and Analyses, Brno, Czech Republic, ²⁹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet; University of Copenhagen, Copenhagen, Denmark
Background/Purpose: Patient reported outcomes (PROs) are important in the treatment evaluation of patients with spondyloarthritis, including axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA). For secukinumab,…
Abstract Number: 1396 • ACR Convergence 2023
Comprehensive Evaluation of the Digital Annular Pulleys: From Ultrasonographical to Anatomical and Histological Evaluation with Special Focus on the Entheses
Luis Coronel¹, Peter Mandl², María Isabel Miguel³, Joan Blasi⁴, Maria Lopez-Lasanta¹, Sara Marsal¹, Maria-Antonietta D'Agostino⁵ and Ingrid Moller⁶, ¹Hospital Universitari Vall d'Hebron, Rheumatology, Barcelona, Spain, ²Department of Rheumatology, Medical University of Vienna, Vienna, Austria, ³Universitat de Barcelona - Campus Bellvitge, Unitat d’anatomía i embriología humana, L'Hospitalet de Llobregat, Barcelona, Spain, ⁴Universitat de Barcelona - Campus Bellvitge, Histologia, L'Hospitalet de Llobregat, Barcelona, Spain, ⁵Universita Cattolica del Sacro Cuore Rome, Courbevoie, France, ⁶Instituto Poal de Reumatología, Barcelona, Spain
Background/Purpose: The digital annular pulleys (DAP) are anatomical structures of soft connective tissue organized as transverse fibers of variable width, thickness, and configuration that overlay…
Abstract Number: 1394 • ACR Convergence 2023
Comorbidities, Not Long-Term Use of Nonsteroidal Anti-Inflammatory Drugs, May Be Associated with Chronic Kidney Disease in Patients with Ankylosing Spondylitis: A Nationwide Population-Based Study
Bon San Koo¹, Subin Hwang¹, Ye-Jee Kim², Soo Min Ahn² and Wook Jang Seo³, ¹Inje University Seoul Paik Hospital, Seoul, South Korea, ²Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea, ³Department of Rheumatology, Veteran Health Service Medical Center, Seoul, South Korea
Background/Purpose: Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed as first-line treatment for symptom relief and inflammation reduction in patients with ankylosing spondylitis (AS). However, long-term…
Abstract Number: 1117 • ACR Convergence 2023
Serum Urate Change Among Gout Patients Initiating Sodium-Glucose Cotransporter Type 2 Inhibitors (SGLT2i) vs. Sulfonylureas: A Comparative Effectiveness Analysis
Chio Yokose¹, Gregory Challener², Baijun Zhou², Natalie McCormick², Sruthi Tanikella², Kila Panchot², Minna Kohler³, Janeth Yinh², Yuqing Zhang⁴, David Bates⁵, James Januzzi², Meghan Sise², Deborah Wexler² and Hyon K. Choi⁶, ¹Massachusetts General Hospital, Waltham, MA, ²Massachusetts General Hospital, Boston, MA, ³Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁴Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, MA, ⁵Brigham and Women's Hospital, Boston, MA, ⁶Massachusetts General Hospital and Harvard Medical School, Lexington, MA
Background/Purpose: Sodium-glucose cotransporter type 2 inhibitors (SGLT2i) are currently indicated as second-line therapy for type 2 diabetes and are also approved for the treatment of…
Abstract Number: 1137 • ACR Convergence 2023
Association Between Nailfold Videocapillaroscopy Findings and sKL-6 Levels in Patients with Idiopathic Inflammatory Myopathies–Related Interstitial Lung Disease
Cristiana Sieiro Santos¹, Jose Luis Tandaipan², Diego Castillo², Laura Martínez Martínez², Helena Codes², Luis Sainz-Comas², Berta Paula Magallares-Lopez³, Patricia Moya², Anais Mariscal², Hye Sang Park², Ana Milena Millán Arciniegas², César Díaz-Torné², Ana Laíz Alonso², Sandra Ros², Susana Fernández², Hector Corominas⁴, Elvira Díez Álvarez⁵ and Iván Castellvi², ¹Complejo Asistencial Universitario de León, León, Spain, ²Hospital de Santa Creu i Sant Pau, Barcelona, Spain, ³Department of Rheumatology, Hospital de la Santa Creu I Sant Pau, Barcelona, Spain, ⁴Hospital Universitario Sant Pau, Rheumatology, Barcelona, Spain, ⁵CAULE, León, Spain
Background/Purpose: Interstitial lung disease (ILD) is a frequent pulmonary manifestation in idiopathic inflammatory myopathies (IIM) (IIM-ILD) and considerably influences morbidity and mortality. Krebs von den…
Abstract Number: 1007 • ACR Convergence 2023
Telehealth Conversion: A Strategy for Optimizing Ambulatory Access
Sancia Ferguson¹, Amanda Nanes², Lori Zemlicka² and Christie M. Bartels³, ¹University of Wisconsin, Madison, WI, ²UW Health, Madison, WI, ³University of Wisconsin, School of Medicine and Public Health, Madison, WI
Background/Purpose: With the rapid uptake of telehealth at the beginning of the pandemic, our group operationalized a simple strategy to convert appointments for patients who…
Abstract Number: 1016 • ACR Convergence 2023
Cost-related Medication Burden for Patients with and Without Systemic Autoimmune Rheumatic Diseases
Jeong Yee¹, Candace Feldman¹, Emily G. Oakes¹, Jack Ellrodt¹, May Choi², Elizabeth Karlson¹ and Karen Costenbader³, ¹Brigham and Women's Hospital, Boston, MA, ²University of Calgary, Calgary, AB, Canada, ³Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose: Medication nonadherence is a challenging issue in the management of systemic autoimmune rheumatic diseases (SARDs), leading to poor clinical outcomes. Although it is complex…
Abstract Number: 1391 • ACR Convergence 2023
Rates of Remission in Patients with Axial Spondyloarthritis Treated in Tertiary Care
Franziska Neinert¹, Imke Redeker², Styliani Tsiami¹, David Kiefer¹, Barbara Guminski¹, Xenofon Baraliakos³, Juergen Braun¹ and Uta Kiltz⁴, ¹Ruhr-Universität Bochum and Rheumazentrum Ruhrgebiet, Herne, Germany, ²Ruhr Universität Bochum, Bochum, Germany, ³Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, ⁴Rheumazentrum Ruhrgebiet, Herne, Germany
Background/Purpose: Achieving remission is the treatment target for patients (pts.) with axial spondyloarthritis (axSpA).Remission rates over longer periods in a real-life setting have not been…
Abstract Number: 1385 • ACR Convergence 2023
Where Are We with Implementing Axial Spondyloarthritis Treatment Recommendations and Disease Activity Monitoring in Clinical Practice – Results of an Online Survey Amongst Rheumatology Care Providers
Joerg Ermann¹, Stephanie Sinnappan² and Alexandra Forte³, ¹Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Brigham and Women's Hospital, Boston, MA, ³Memorial Sloan Kettering Cancer Center, New York, NY
Background/Purpose: Several sets of treatment recommendations for axial spondyloarthritis and ankylosing spondylitis (axSpA/AS) have been published. Clinical practice guidelines are not followed consistently by health…
Abstract Number: 1128 • ACR Convergence 2023
Refractory Inflammatory Ocular Pathology and Treatment with Janus Kinase Inhibitors. Multicenter Study and Literature Review
Carmen Lasa-Teja¹, Lara Sanchez-Bilbao², Jose Luis Martin-Varillas³, Vanesa Calvo Río⁴, José Luis Álvarez-Vega⁵, Emma Beltran-Catalan⁶, María del Mar Esteban-Ortega⁷, Santiago Muñoz⁷, Olga Maiz⁸, Ignacio Torre-Salaberri⁹, Ana Urruticoechea¹⁰, Elia Valls-Pascual¹¹, Raúl Veroz¹², Carmen Alvarez Reguera¹³, Rosalía Demetrio¹³ and Ricardo Blanco¹⁴, ¹Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology Group, Santander, Spain, ²Hospital Universitario Marques de Valdecilla, Santander, Spain, ³Hospital de Laredo, Laredo, Spain, ⁴Valdecilla Hospital, Santander, Spain, ⁵Complejo Hospitalario Universitario de Badajoz, Badajoz, Spain, ⁶HOSPITAL DEL MAR, Barcelona, Spain, ⁷Hospital Infanta Sofia, Madrid, Spain, ⁸Hospital Universitario de Donostia. San Sebastián, Spain., Donosti, Spain, ⁹Hospital Universitario de Basurto, Bilbao, Spain, ¹⁰Hospital Can Misses, Ibiza, Spain, ¹¹Hospital Universitario Doctor Peset. Alicante, Spain., Valencia, Spain, ¹²Hospital de Mérida, Mérida. Spain., Mérida, Spain, ¹³Hospital Universitario Marqués de Valdecilla, Santander, Spain, ¹⁴Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain
Background/Purpose: Inflammatory ocular pathology (IOP) includes internal (uveitis) and external [mainly ocular surface pathology such as epi/scleritis and peripheral ulcerative keratitis (PUK)] involvement. IOP may…
Abstract Number: 1397 • ACR Convergence 2023
Sustainability of Clinical Response at Week 52 to Upadacitinib Among Patients with Axial SpA: Data from the SELECT-AXIS 1 and SELECT-AXIS 2 Trials
Victoria Navarro-Compán¹, Lianne Gensler², Martin Rudwaleit³, Fabiana Ganz⁴, Shirley Chen⁴, Jayne Stigler⁴, Anna Schmagel⁴ and Xenofon Baraliakos⁵, ¹Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain, ²University of California San Francisco, Department of Medicine, Division of Rheumatology, San Francisco, CA, ³University of Bielefeld, Klinikum Bielefeld, Bielefeld, Germany, ⁴AbbVie, Inc., North Chicago, IL, ⁵Rheumazentrum Ruhrgebiet Herne, Ruhr University Bochum, Bochum, Germany
Background/Purpose: Upadacitinib 15 mg (UPA), an oral Janus kinase inhibitor, has shown efficacy and tolerability through 14 weeks in patients (pts) with active radiographic axial…
Abstract Number: 1403 • ACR Convergence 2023
MRI-defined Sacroiliitis in First Degree Relatives of Ankylosing Spondylitis Patients
Kristyna Bubova¹, Lenka Hasikova², Katerina Mintalova², Monika Gregova², Sarka Forejtova², Ladislav Senolt³ and Karel Pavelka⁴, ¹Institute of Rheumatology, Prague, Czech Republic, ²Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Prague, Czech Republic, ³Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Praha, Czech Republic, ⁴Institut of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Praha, Czech Republic
Background/Purpose: Sacroiliitis is a main radiographic finding in axial spondyloarthritis (axSpA) - the inflammatory rheumatic disease with a strong genetic background. The aim of this…
Abstract Number: 1398 • ACR Convergence 2023
A Deep Learning Algorithm for MRI Spinal Inflammation in Axial Spondyloarthritis
Shirley Chiu Wai Chan¹, Ying Ying Lin², Ho Yin Chung¹, Kam Ho Lee³ and Peng Cao², ¹Divison of Rheumatology and Clinical Immunology, Department of Medicine, Queen Mary Hospital, the University of Hong Kong, Hong Kong, Hong Kong, ²Department of Diagnostic Radiology, the University of Hong Kong, Hong Kong, Hong Kong, ³Department of Radiology, Queen Mary Hospital, Hong Kong, Hong Kong, Hong Kong
Background/Purpose: Deep learning has achieved wide applications in different areas of medical imaging analysis. Limited studies have explored the use of deep learning for imaging…
Abstract Number: 1148 • ACR Convergence 2023
A Comparative Study of Clinical Phenotype in Relation to NOD2 Sub-genotypes in Yao Syndrome
Ashmia Saif¹, Hafsa Nomani², Frank Hwang², Jie Yang² and Qingping Yao², ¹Stony Brook University Hospital, Syosset, NY, ²Stony Brook University, Stony Brook, NY
Background/Purpose: Yao syndrome (YAOS, OMIM 617321) is formerly designated NOD2-associated autoinflammatory disease. A spectrum of NOD2 mutations have been associated with this disease. Most patients…

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