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  • Abstract Number: 282 • 2012 ACR/ARHP Annual Meeting

    Clinical and Laboratory Features Distinguishing Juvenile Polymyositis and Muscular Dystrophy in Children

    Gulnara Mamyrova1, James D. Katz1, Robert V. Jones2, Peter A. Lachenbruch3, Mona Shah3, Olcay Y. Jones1, Anupam Chahal1, Seema Agrawal1, Frederick W. Miller3, Lisa G. Rider3 and the Childhood Myositis Heterogeneity Group4, 1Rheumatology, George Washington University, Washington, DC, 2Pathology, George Washington University, Washington, DC, 3Environmental Autoimmunity Group, NIEHS, NIH, Bethesda, MD, 4Niehs, NIH, Bethesda, MD

    Background/Purpose: We examined demographic, clinical and laboratory features of juvenile polymyositis (JPM) and muscular dystrophy in children to improve classification of these two conditions. Methods:…
  • Abstract Number: 283 • 2012 ACR/ARHP Annual Meeting

    Hospitalizations for Patients with Chilhood-Onset Systemic Lupus Erythematosus in the Pediatric Health Information System Databse

    Aimee O. Hersh1, Charlie Casper1, Tellen D. Bennett1, Susan L. Bratton1, John F. Bohnsack2 and Rajendu Srivastava1, 1Pediatrics, University of Utah, Salt Lake City, UT, 2Dept of Pediatriacs, University of Utah, Salt Lake City, UT

    Background/Purpose: To describe patient demographics, admission characteristics and clinical care for hospitalized patients with childhood-onset systemic lupus erythematous (SLE). Methods: Retrospective cohort study of the…
  • Abstract Number: 284 • 2012 ACR/ARHP Annual Meeting

    Treatment and Outcome of ANCA-Associated Vasculitis in Children: A Pilot Study

    Marinka Twilt1, Audrey Bell-Peter1, Ronald Laxer2, Christian Pagnoux3, Diane Hebert4, Elizabeth Harvey4, Shehla Sheikh2 and Susanne M. Benseler2, 1Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 2Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 3Rheumatology, Mount Sinai Hospital, Toronto, Canada, Toronto, ON, Canada, 4Nephrology, The Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: Childhood ANCA vasculitides are rare, yet organ- or even life-threatening systemic vasculitides. Children most frequently present with rapidly evolving, severe disease such as pulmonary-renal…
  • Abstract Number: 285 • 2012 ACR/ARHP Annual Meeting

    Rituximab for Severe Disease Flares in Childhood ANCA Vasculitides

    Marinka Twilt1, Rayfel Schneider2, Audrey Bell-Peter1, Sharon Dell3 and Susanne M. Benseler4, 1Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 2Pediatric Rheumatology Collaborative Study Group (PRCSG), Cincinnati, OH, Canada, 3Respiratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada, 4Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: Children with ANCA vasculitides frequently present with life-threatening organ manifestations including alveolar hemorrhage, critical subglottic stenosis and renal failure due to rapidly progressive glomerulonephritis…
  • Abstract Number: 286 • 2012 ACR/ARHP Annual Meeting

    The Association of N-Methyl-D-Aspartate Receptor Antibodies and Neurocognitive Dysfunction in Pediatric Lupus Patients and in the Offspring of Adult Patients with Lupus

    Natasha M. Ruth1, Mary C. Kral2, Stephanie Slan3, Tamara K. Nowling4, Murray H. Passo1 and Gary S. Gilkeson3, 1Pediatric Rheumatology, Medical University of South Carolina, Charleston, SC, 2Genetics and Developmental Pediatrics, MUSC, Charleston, SC, 3Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, SC, 4Medical University of South Carolina, Charleston, SC

    Background/Purpose: Approximately 1/5 of all systemic lupus erythematosus (SLE) starts in childhood and central nervous system (CNS) dysfunction is more common in childhood-onset SLE.  CNS…
  • Abstract Number: 287 • 2012 ACR/ARHP Annual Meeting

    Variation in Healthcare Utilization by Region and Number of Rheumatologists Per State Among Pediatric Medicaid Patients with Lupus Nephritis Prior to End-Stage Renal Disease in the United States, 2000-2004

    Linda T. Hiraki1, Candace H. Feldman2, Graciela S. Alarcon3, Jun Liu4, Michael A. Fischer5, Wolfgang C. Winkelmayer6 and Karen H. Costenbader7, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard School of Public Health, Boston, MA, 2Rheumatology, Brigham and Women's Hospital, Boston, MA, 3Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, 4Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Harvard Medical School, Boston, Boston, MA, 5Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Boston, MA, 6Division of Nephrology, Stanford University School of Medicine, Stanford, CA, 7Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Unequal healthcare access and utilization may contribute to the striking sociodemographic disparities seen in outcomes for children with lupus nephritis. Medicaid is the U.S.…
  • Abstract Number: 288 • 2012 ACR/ARHP Annual Meeting

    Validation of Promis Modules for Use in Childhood-Onset Lupus

    Alexandria J. Greenler1, Laura E. Schanberg2, Michael P. Flannery1, Shannen Nelson3, Janet Wootton4, Esi M. Morgan DeWitt3 and Hermine Brunner5, 1Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Pediatrics, Duke University Medical Center, Durham, NC, 3Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Pediatric Rheumatology, Duke University Medical Center, Durham, NC, 5Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose:  The impact of childhood-onset lupus (cSLE) and its treatment on quality of life (QoL) has not been systematically established. The Patient Reported Outcomes Measurement…
  • Abstract Number: 247 • 2012 ACR/ARHP Annual Meeting

    Meager Depression Screening and Mental Health Referral Rates for Patients with Arthritis in a National Sample

    Mary Margaretten1, Patricia P. Katz2, Laura Trupin2, Gabriela Schmajuk3, Jennifer Barton4, Jinoos Yazdany5 and Edward H. Yelin6, 1Rheumatology, University of California, San Francisco, San Francisco, CA, 2Medicine, UCSF, San Francisco, CA, 3Rheumatology, UCSF / San Francisco VA Medical Center, San Francisco, CA, 4Medicine, University of California, San Francisco, San Francisco, CA, 5Rheumatology, UCSF, San Francisco, CA, 6Arthritis Research Group, UCSF, San Francisco, CA

    Background/Purpose: Depression in patients with arthritis is common and leads to poor health outcomes. While it has been shown that rheumatologists rarely communicate about depression…
  • Abstract Number: 248 • 2012 ACR/ARHP Annual Meeting

    Synovial Fluid Leptin Level Is Associated with Residual Pain and Functional Disability One Year After Total Joint Arthroplasty

    Anne Lübbeke1, Gabor J. Puskas1, Axel Finckh2, Domizio Suva1, Sylvette Bas3, Cem Gabay3, Daniel Fritschy1 and Pierre Hoffmeyer1, 1Orthopaedic Surgery, Geneva University Hospitals, Geneva, Switzerland, 2Rheumatology, Geneva University Hospitals, Geneva 14, Switzerland, 3Rheumatology, Geneva University Hospitals, Geneva, Switzerland

    Background/Purpose:  A sizeable number of patients continue to suffer from pain, functional disability and reduced quality of life after total joint arthroplasty (TJA). The etiology…
  • Abstract Number: 249 • 2012 ACR/ARHP Annual Meeting

    Medial Subchondral Bone Marrow Lesions Increase the Odds of Knee Joint Replacement – Data From the Osteoarthritis Initative

    Frank Roemer1, C. Kent Kwoh2, David Hunter3, Michael J. Hannon4, Robert M. Boudreau5, Felix Eckstein6, Zhijie Wang4, Markus R. John7 and Ali Guermazi8, 1Klinikum Augsburg, Augsburg, Germany, 2School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 3Royal North Shore Hospital, St. Leonards, Australia, 4Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, 5Epidemiology, University of Pittsburgh, Pittsburgh, PA, 6Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, 7Novartis Pharma AG, Basel, Switzerland, 8Boston University, Boston, MA

    Background/Purpose: Knee joint replacement (KR) is a cost-effective procedure with good long-term outcomes. However, there is no clear consensus on indications for KR. Subchondral bone…
  • Abstract Number: 250 • 2012 ACR/ARHP Annual Meeting

    Incident and Worsening Cartilage Damage in the Lateral Compartment and Multiple Subregions Worsening in the Medial Compartment Increase the Risk for Knee Replacement – Data From the Osteoarthritis Initiative

    Frank Roemer1, C. Kent Kwoh2, Michael J. Hannon3, Robert M. Boudreau4, Felix Eckstein5, David J. Hunter6, Zhijie Wang3, Markus R. John7 and Ali Guermazi8, 1Klinikum Augsburg, Augsburg, Germany, 2School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 3Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, 4Epidemiology, University of Pittsburgh, Pittsburgh, PA, 5Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, 6Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, 7Novartis Pharma AG, Basel, Switzerland, 8Boston University, Boston, MA

    Background/Purpose: Knee joint replacement (KR) is a cost-effective procedure with good long-term outcomes. However, at present there is no clear consensus on indications for KR.…
  • Abstract Number: 251 • 2012 ACR/ARHP Annual Meeting

    Smaller Baseline and Follow-up Quadriceps Muscle Cross-Sectional Area Increases the Odds of Knee Replacement in Knee Osteoarthritis

    Serter Gumus1, Michael J. Hannon2, Diana Kaya1, C. Kent Kwoh3 and Kyongtae Ty Bae1, 1Radiology, University of Pittsburgh, Pittsburgh, PA, 2Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, 3School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Knee osteoarthritis (OA) is one of the major causes of disability among elderly. Knee replacement (KR) is the final effective treatment of OA after…
  • Abstract Number: 252 • 2012 ACR/ARHP Annual Meeting

    Presence of Severe Medial Mensical Pathology Increases the Odds for Knee Replacement: Data From the Osteoarthritis Initiative

    Frank Roemer1, C. Kent Kwoh2, David J. Hunter3, Robert M. Boudreau4, Michael J. Hannon5, Markus R. John6, Felix Eckstein7, Michel Crema8, Zhijie Wang5 and Ali Guermazi8, 1Klinikum Augsburg, Augsburg, Germany, 2School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 3Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, 4Epidemiology, University of Pittsburgh, Pittsburgh, PA, 5Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, 6Novartis Pharma AG, Basel, Switzerland, 7Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, 8Boston University, Boston, MA

    Background/Purpose: Knee joint replacement (KR) is a cost-effective procedure with good long-term outcome. However, at present there is no clear consensus on indications for KR.…
  • Abstract Number: 253 • 2012 ACR/ARHP Annual Meeting

    Incidence of Osteoarthritis-Related Knee and Hip Joint Surgery in Southern Sweden

    Aleksandra Turkiewicz1, Ingemar F. Petersson2, Leif E. Dahlberg1 and Martin Englund1, 1Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden, 2Lund University, Lund, Sweden

    Background/Purpose: To estimate the incidence and age and sex patterns of subjects having had osteoarthritis (OA)-related surgical treatment. Methods: The Skåne Health Care Register (SHCR)…
  • Abstract Number: 254 • 2012 ACR/ARHP Annual Meeting

    Effects of Strontium Ranelate On Knee Osteoarthritis Pain: A Responder Analysis

    JY. Reginster1, Roland Chapurlat2, N. Bellamy3, E. Czerwinski4, JP Devogelaer5, Lyn March6, K. Pavelka7 and Cyrus Cooper8, 1Department of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium, 2Hôpital Edouard Herriot, Lyon, France, 3CONROD. The University of Queensland, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia, 4Krakow Medical Centre, Kraków, Poland, 5Service de Rhumatologie, Cliniques Universitaires St. Luc, Brussels, Belgium, 6University of Sydney, Institute of Bone and Joint Research, Royal North Shore Hospital, St Leonards - Sydney, Australia, 7Department of Clinical and Experimental Rheumatology, Charles University, Prague, Czech Republic, 8NDORMS; MRC Lifecourse Epidemiology Unit, University of Oxford; Southampton General Hospital, Southampton, United Kingdom

    Background/Purpose: In a large, randomised, placebo-controlled, double-blind phase-III 3-year study (SEKOIA), strontium ranelate 2g/day (SrRan) has demonstrated structure-modifying activity associated with statistically significant symptomatic improvement…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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