ACR Meeting Abstracts

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  • Abstract Number: 0349 • ACR Convergence 2023

    Disease Activity of Juvenil Idiopathic Arthritis in Transitional Care

    Karen Carpio Astudillo1, Daniel clemente Garulo2, Juan Carlos Lopez-Robledillo3, Camille Bourgeois Avella4, Laura Trives Folguera4, Amparo López López1, Jose María Alvaro-Gracias4, Indalecio Monteagudo Sáez1 and Juan carlos Nieto-Gonzalez5, 1Hospital General Universitario Gregorio Marañón, Madrid, Spain, 2Pediatric Rheumatology Unit, Hospital Niño Jesús, Madrid, Spain, 3Hospital Infantil Universitario Niño Jesús, Madrid, Spain, 4Hospital General Universitario Gregorio Marañon, Madrid, Spain, 5Servicio de Reumatología, Hospital General Universitario Gregorio Marañón, Madrid, Spain

    Background/Purpose: Juvenile Idiopathic Arthritis (JIA) are a group of heterogeneous arthritis with onset in childhood. According to previous studies, this patients experience an improvement of…
  • Abstract Number: 1377 • ACR Convergence 2023

    Characterization of Pulmonary Manifestations of Sjögren Syndrome: A Multicenter Retrospective Study

    Loïc Meudec1, Cindy Marques2, Pierre-Antoine Juge3, Robin Dhote4, Anne-Laure Fauchais5, Emanuelle Dernis6, Olivier Vittecoq7, Alain SARAUX8, Jacques-Eric Gottenberg9, Eric Hachulla10, Véronique Le Guern11, Philippe Dieudé12, Marie-Pierre Debray13, Antoine Beurnier14, Raphaele Seror15, Xavier Mariette16 and Gaetane Nocturne17, 1CHU Kremlin-Bicêtre, Rheumatology, Le Kremlin-Bicêtre, France, 2CHU Pitié Salpétrière, Internal Medicine 1, Paris, France, 3Division of Rheumatology, Inflammation, and Immunity Brigham & Women’s Hospital, Boston, MA, 4Department of Internal Medicine, Centre Hospitalier Avicenne, Bobigny, France, 5Dupuytren Hospital, Limoges, France, 6CH Le Mans, Le Mans, France, 7CHU Rouen, Rheumatology, Rouen, France, 8CHU Brest, Brest, France, 9Rheumatology Department, Strasbourg University Hospital, Strasbourg, France, 10CHU Lille, Département de Médecine Interne et Immunologie Clinique, Centre de Référence des Maladies Auto-immunes Systémiques Rares du Nord et Nord-Ouest de France (CeRAINO), Lille, France, 11APHP Hôpital Cochin, Paris, France, 12Assistance Publique-Hôpitaux de Paris, Bichat-Claude Bernard University Hospital, INSERM UMR1152, University de Paris Cité, Department of Rheumatology, Paris, France, 13CHU Bichat, Radiology, Paris, France, 14CHU Kremlin-Bicêtre, Functional Explorations, Le Kremlin-Bicêtre, France, 15University Hospital Paris Saclay, Le Kremlin-Bicêtre, France, 16Université Paris-Saclay, Le Kremlin-Bicêtre, France, 17APHP, Le Kremlin-Bicêtre, France

    Background/Purpose: Sjögren disease (Sjo) is a systemic immune-related disease with pulmonary manifestations occurring in up to 16% of patients [1], including interstitial lung disease (SS-ILD)…
  • Abstract Number: 1375 • ACR Convergence 2023

    The Relative Burden of Fatigue Is Associated with High TSH/fT4 Ratio in Korean Patients with Primary Sjogren’s Syndrome

    Jee-in Lee1, Se Rim Choi2, You-Jung Ha2, Eun Ha Kang3, Keun-Suh Kim4, Joon Young Hyon5 and Yun Jong Lee6, 1Seoul National University of Bundang Hospital, Seongnam, South Korea, 2Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnamsi, South Korea, 3Seoul National University Bundang Hospital, Seongnam, South Korea, 4Department of Periodontology, Section of Dentistry, Seoul National University Bundang Hospital, Seongnamsi, South Korea, 5Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnamsi, South Korea, 6Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam-si, South Korea

    Background/Purpose: To investigate the prevalence of anti-thyroid autoantibodies, abnormal thyroid function, and their clinical impacts in Korean patients with primary Sjögren's syndrome (pSS). Methods: One…
  • Abstract Number: 1117 • ACR Convergence 2023

    Serum Urate Change Among Gout Patients Initiating Sodium-Glucose Cotransporter Type 2 Inhibitors (SGLT2i) vs. Sulfonylureas: A Comparative Effectiveness Analysis

    Chio Yokose1, Gregory Challener2, Baijun Zhou2, Natalie McCormick2, Sruthi Tanikella2, Kila Panchot2, Minna Kohler3, Janeth Yinh2, Yuqing Zhang4, David Bates5, James Januzzi2, Meghan Sise2, Deborah Wexler2 and Hyon K. Choi6, 1Massachusetts General Hospital, Waltham, MA, 2Massachusetts General Hospital, Boston, MA, 3Massachusetts General Hospital, Harvard Medical School, Boston, MA, 4Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, MA, 5Brigham and Women's Hospital, Boston, MA, 6Massachusetts General Hospital and Harvard Medical School, Lexington, MA

    Background/Purpose: Sodium-glucose cotransporter type 2 inhibitors (SGLT2i) are currently indicated as second-line therapy for type 2 diabetes and are also approved for the treatment of…
  • Abstract Number: 1038 • ACR Convergence 2023

    Improved Assessment of Structural Damage in the Spine in Patients with Axial Spondyloarthritis by MRI-based Synthetic CT: A Comparison with Low-dose CT and X-ray

    Simone Tromborg Willesen1, Nora Vladimirova1, Jakob Moeller2, Anna Enevold Fløistrup Hadsbjerg1, Bimal Mayur Kumar Vora3, Sengul Seven1, Susanne Juhl Pedersen1 and Mikkel Østergaard1, 1Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet; University of Copenhagen, Copenhagen, Denmark, 2Herlev-Gentofte Hospital, Herlev, Denmark, 3Singapore General Hospital, Singapore, Singapore

    Background/Purpose: Whether a therapy has bone structure-modifying effects in the spine is crucial to determine since this is a prerequisite for a therapy to reduce…
  • Abstract Number: 1137 • ACR Convergence 2023

    Association Between Nailfold Videocapillaroscopy Findings and sKL-6 Levels in Patients with Idiopathic Inflammatory Myopathies–Related Interstitial Lung Disease

    Cristiana Sieiro Santos1, Jose Luis Tandaipan2, Diego Castillo2, Laura Martínez Martínez2, Helena Codes2, Luis Sainz-Comas2, Berta Paula Magallares-Lopez3, Patricia Moya2, Anais Mariscal2, Hye Sang Park2, Ana Milena Millán Arciniegas2, César Díaz-Torné2, Ana Laíz Alonso2, Sandra Ros2, Susana Fernández2, Hector Corominas4, Elvira Díez Álvarez5 and Iván Castellvi2, 1Complejo Asistencial Universitario de León, León, Spain, 2Hospital de Santa Creu i Sant Pau, Barcelona, Spain, 3Department of Rheumatology, Hospital de la Santa Creu I Sant Pau, Barcelona, Spain, 4Hospital Universitario Sant Pau, Rheumatology, Barcelona, Spain, 5CAULE, León, Spain

    Background/Purpose: Interstitial lung disease (ILD) is a frequent pulmonary manifestation in idiopathic inflammatory myopathies (IIM) (IIM-ILD) and considerably influences morbidity and mortality. Krebs von den…
  • Abstract Number: 1378 • ACR Convergence 2023

    The UCSD Shortness of Breath Questionnaire Is a Useful Tool for the Assessment of Dyspnea in Primary Sjögren’s Syndrome Patients with Interstitial Lung Disease: A Monocentric Cross-Sectional Study

    Gaetano La Rocca1, Francesco Ferro2, Elena Elefante3, Silvia Fonzetti4, Giovanni Fulvio5, Inmaculada Conception Navarro Garcia3, Chiara Romei6, Marta Mosca3 and Chiara Baldini5, 1University of Pisa, Rheumatology Unit, Pisa, Italy, 2Clinical and Experimental Medicine Department, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy, 3Rheumatology Unit, Department of clinical and experimental medicine, University of Pisa, Pisa, Italy, 4AOUP, Pisa, Italy, 5University of Pisa, Pisa, Italy, 6Department of Diagnostic Imaging, Diagnostic Radiology 2, Pisa University Hospital, Pisa, Italy

    Background/Purpose: In clinical trials investigating new drugs for the management of Interstitial Lung Disease (ILD) patient reported outcomes (PRO) are increasingly employed as outcome measures…
  • Abstract Number: 0814 • ACR Convergence 2023

    Treat-to-target Urate-lowering Therapy Reduces Gout Flare Burden: Post-hoc Analysis of a Multicenter, Randomized, Double-blind, Non-inferiority Trial

    Joshua Qu1, Lindsay Helget1, Maria Androsenko2, Hongsheng Wu3, Bridget Kramer1, Jefferey Newcomb4, Mary Brophy3, Anne Davis-Karim5, Bryant England1, Ryan Ferguson3, Michael Pillinger6, Tuhina Neogi7, Paul Palevsky8, James O'Dell1 and Ted R Mikuls9, 1University of Nebraska Medical Center, Omaha, NE, 2Department of VA, Newton, MA, 3Boston VA, Boston, MA, 4University of Nebraska, Omaha, NE, 5Albuquerque VA, Albuquerque, NM, 6New York University Grossman School of Medicine, New York, NY, 7Boston University School of Medicine, Boston, MA, 8University of Pittsburgh, Pittsburgh, PA, 9Division of Rheumatology and Immunology, University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: To optimally manage gout, the ACR recommends a treat-to-target (T2T) strategy, which entailsthe titration of urate-lowering therapy (ULT) to achieve and maintain a serum…
  • Abstract Number: 1381 • ACR Convergence 2023

    Fatigue and Associated Factors in Patients with Primary Sjogren’s Syndrome Compared to Secondary Sjogren’s Syndrome

    Hyeji Jeon, Hyun-Sook Kim and Kyung-Ann Lee, Soonchunhyang University Seoul Hospital, Seoul, South Korea

    Background/Purpose: Fatigue is one of the dominant symptoms of patients with Primary Sjogren's syndrome (pSS). However, whether fatigue is specific to pSS compared to secondary…
  • Abstract Number: 1047 • ACR Convergence 2023

    Infrared Thermography Imaging Discriminates Between Inflamed and Non-inflamed Joints

    Maria I. ("Maio") Danila1, Giovanna Rosas2, Fenglong Xie2, Jeffrey R Curtis3, Kiara Aaron2, Stephanie Ford2 and Laura Hughes4, 1University of Alabama at Birmingham (UAB), Birmingham VA Medical Center, Birmingham, AL, 2University of Alabama at Birmingham, Birmingham, AL, 3Division of Clinical Immunology and Rheumatology, University of Alabama, Birmingham, AL, 4University of Alabama at Birmingham; East Alabama Medical Center, Birmingham, AL

    Background/Purpose: Infrared thermography (IRT) is an emerging technology that has the potential to rapidly assist in identifying joint inflammation in patients with joint symptoms. However,…
  • Abstract Number: 1388 • ACR Convergence 2023

    Pain Mechanisms in Psoriatic Arthritis: Differentiating Inflammation Related Pain in Enthesitis Using Ultrasound, in Comparison to Functional MRI

    Ummugulsum Gazel1, Kristen Noges2, Burak Ayan2, Gizem Ayan3, Olivier Brown1, Andra Smith1 and sibel aydin4, 1University of Ottawa, Ottawa, ON, Canada, 2University of Ottawa, Rheumatology, Ottawa, ON, Canada, 3Hacettepe University Faculty of Medicine Division of Rheumatology, Ankara, Turkey, 4University of Ottawa - Ottawa, Ottawa, ON, Canada

    Background/Purpose: Approximately 50% of PsA patients have persistent pain despite a well‐controlled inflammatory state, which has been attributed to non‐nociceptive pain and central sensitization. Enthesitis…
  • Abstract Number: 0812 • ACR Convergence 2023

    Length of Synovial Fluid Monosodium Urate Crystals According to Sonographic Articular Deposits: Advancing in the Crystallization Process

    Elena Sansano1, Mª Carmen López-González2, Cristina Rodríguez-Alvear3, Irene Calabuig-Sais3, Agustín Martínez-Sanchís3, Eliseo Pascual3 and Mariano Andrés3, 1Miguel Hernandez University, Alicante, Spain, 2General University Hospital Dr. Balmis, Alacante, Spain, 3Dr Balmis Alicante General University Hospital-ISABIAL, Alicante, Spain

    Background/Purpose: We described bands of fibers having deposited orderly arrayed monosodium urate (MSU) crystals suggesting the need for protein templates to start crystallization [PMID 9709185].…
  • Abstract Number: 1128 • ACR Convergence 2023

    Refractory Inflammatory Ocular Pathology and Treatment with Janus Kinase Inhibitors. Multicenter Study and Literature Review

    Carmen Lasa-Teja1, Lara Sanchez-Bilbao2, Jose Luis Martin-Varillas3, Vanesa Calvo Río4, José Luis Álvarez-Vega5, Emma Beltran-Catalan6, María del Mar Esteban-Ortega7, Santiago Muñoz7, Olga Maiz8, Ignacio Torre-Salaberri9, Ana Urruticoechea10, Elia Valls-Pascual11, Raúl Veroz12, Carmen Alvarez Reguera13, Rosalía Demetrio13 and Ricardo Blanco14, 1Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology Group, Santander, Spain, 2Hospital Universitario Marques de Valdecilla, Santander, Spain, 3Hospital de Laredo, Laredo, Spain, 4Valdecilla Hospital, Santander, Spain, 5Complejo Hospitalario Universitario de Badajoz, Badajoz, Spain, 6HOSPITAL DEL MAR, Barcelona, Spain, 7Hospital Infanta Sofia, Madrid, Spain, 8Hospital Universitario de Donostia. San Sebastián, Spain., Donosti, Spain, 9Hospital Universitario de Basurto, Bilbao, Spain, 10Hospital Can Misses, Ibiza, Spain, 11Hospital Universitario Doctor Peset. Alicante, Spain., Valencia, Spain, 12Hospital de Mérida, Mérida. Spain., Mérida, Spain, 13Hospital Universitario Marqués de Valdecilla, Santander, Spain, 14Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: Inflammatory ocular pathology (IOP) includes internal (uveitis) and external [mainly ocular surface pathology such as epi/scleritis and peripheral ulcerative keratitis (PUK)] involvement. IOP may…
  • Abstract Number: 1387 • ACR Convergence 2023

    Power Doppler Musculoskeletal Abnormalities in Patients with Psoriasis at High Risk of Progression to Psoriatic Arthritis

    Rebecca Haberman1, Sarah Moussavi1, Yan Zhang1, Sydney Catron1, Jonathan Samuels2, Rebecca Blank3, Michael Toprover4, Jiyuan Hu1, Cinty Gong5, Vincent Piguet6, Francisco Tausk7, Jensen Yeung8, Andrea Neimann1, Wayne Gulliver9, Joseph Merola10, Alexis R Ogdie11, Proton Rahman12, Soumya Chakravarty13, Ralf Thiele14, Lihi Eder15, Christopher T Ritchlin16 and Jose Scher17, 1NYU Grossman School of Medicine, New York, NY, 2NYU Langone, Rye Brook, NY, 3New York University, New York, NY, 4New York University Langone Health, New York, NY, 5Immunology, Janssen Scientific Affairs, LLC, Horsham, PA, USA, Raritan, NJ, 6Women's College Hospital, Toronto, ON, Canada, 7University of Rochester Medical Center, Rochester, NY, 8University of Toronto and Women’s College Hospital, Toronto, ON, Canada, 9Memorial University of Newfoundland, St. John's, NL, Canada, 10Harvard Medical School, Brigham and Women's Hospital, Newton, MA, 11University of Pennsylvania, Philadelphia, PA, 12Craig Dobbin Research Institute, Memorial University, St. John's, NL, Canada, 13Immunology, Janssen Scientific Affairs, LLC / Division of Rheumatology, Drexel University College of Medicine, Villanova, PA, 14University of Rochester, Pittsford, NY, 15Women’s College Research Institute, Division of Rheumatology, University of Toronto, Toronto, ON, Canada, 16University of Rochester Medical School, Allergy, Immunology & Rheumatology Division, Canandaigua, NY, 17New York University School of Medicine, New York, NY

    Background/Purpose: Psoriatic arthritis (PsA) is an immune-mediated disease associated with skin psoriasis that, if untreated, can lead to joint destruction. Up to 30% of patients…
  • Abstract Number: 1148 • ACR Convergence 2023

    A Comparative Study of Clinical Phenotype in Relation to NOD2 Sub-genotypes in Yao Syndrome

    Ashmia Saif1, Hafsa Nomani2, Frank Hwang2, Jie Yang2 and Qingping Yao2, 1Stony Brook University Hospital, Syosset, NY, 2Stony Brook University, Stony Brook, NY

    Background/Purpose: Yao syndrome (YAOS, OMIM 617321) is formerly designated NOD2-associated autoinflammatory disease. A spectrum of NOD2 mutations have been associated with this disease. Most patients…
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