Abstracts Archive - Page 2546 of 2607 - ACR Meeting Abstracts

Abstract Number: 861 • 2012 ACR/ARHP Annual Meeting
A Family Based Pedometer Walking Program in an Adolescent Population with Juvenile Idiopathic Arthritis
Sara M. Stern¹, Jill R. Blitz², Amber Richards² and Katherine AB Marzan³, ¹Pediatric Rheumatology, Children's Hospital Los Angeles, Los Angeles, CA, ²Rehab Services, Children's Hospital Los Angeles, Los Angeles, CA, ³Division of Rheumatology, Children's Hospital Los Angeles, Los Angeles, CA
Background/Purpose: Walking programs are effective in adult arthritis but have not been studied in adolescents with arthritis. The study’s objective was to evaluate the impact…
Abstract Number: 862 • 2012 ACR/ARHP Annual Meeting
What Is the Impact of a Transition Program On Adolescents with Juvenile Idiopathic Arthritis and Their Parents ?
Deborah Hilderson¹, Rene Westhovens², Rik Joos³, Carine H. Wouters⁴ and Philip Moons⁵, ¹Department of Paediatrics; Centre for Health Services and Nursing Research, University Hospital Leuven, KU Leuven, Leuven, Belgium, ²Rheumatology Department of development and regeneration, University Hospital KU Leuven, Leuven, Belgium, ³PRINTO, Genoa, Italy, ⁴Pediatric Rheumatology, University Hospital KU Leuven, Leuven, Belgium, ⁵Centre for Health Services and Nursing Research, KU Leuven, Leuven, Belgium
Background/Purpose: To date, there is no structured or systematic approach in Belgium for transferring adolescents with juvenile idiopathic arthritis from pediatric rheumatology to an adult…
Abstract Number: 863 • 2012 ACR/ARHP Annual Meeting
Employment of a Needs Assessment Survey to Shape a Novel Web-Based Pediatric Rheumatology Curriculum for Primary Care Providers
Amy L. Woodward and Z. Leah Harris, Pediatrics, Vanderbilt University School of Medicine, Nashville, TN
Background/Purpose: Pediatric rheumatology faces many challenges due to the shortage of board certified physicians in the field and the imbalance in their geographic distribution. This…
Abstract Number: 864 • 2012 ACR/ARHP Annual Meeting
Will I Waste Your Time? Delays in Help-Seeking for RA Flares
Caroline A. Flurey¹, Marianne Morris², Jon Pollock¹, Rodney A. Hughes³, Pamela Richards⁴ and Sarah Hewlett⁵, ¹Faculty of Health and Life Sciences, University of the West of England, Bristol, United Kingdom, ²University of the West of England, Bristol, United Kingdom, ³Rheumatology, St. Peters Hospital, Chertsey Surrey, United Kingdom, ⁴Academic Rheumatology Unit, University of Bristol, Bristol, United Kingdom, ⁵Academic Rheumatology, University of the West of England, Bristol, United Kingdom
Background/Purpose: Anecdotal evidence suggests that patients vary in how long they wait before seeking medical help for an RA flare. The aim of this research…
Abstract Number: 865 • 2012 ACR/ARHP Annual Meeting
A Methodology for Estimating Disease State Transitions: Repeated Measures Markov Models with Covariate Dependence
George W. Reed¹, Andrew S. Koenig², Katherine C. Saunders³, David H. Collier⁴, Joel M. Kremer⁵ and Sameer Kotak⁶, ¹University of Massachusetts Medical School, Worcester, MA, ²Specialty Care, Pfizer Inc, Collegeville, PA, ³Corrona, LLC., Southborough, MA, ⁴Amgen Inc., Thousand Oaks, CA, ⁵Albany Medical College and The Center for Rheumatology, Albany, NY, ⁶Specialty Care, Pfizer Inc., New York, NY
Background/Purpose: Many RA patients have variable disease activity over time due to disease flare, reduction in efficacy of current medications and other disease mediating…
Abstract Number: 866 • 2012 ACR/ARHP Annual Meeting
Pain Is Associated with Telomere Shortening in Women with Fibromyalgia
Afton L. Hassett¹, Daniel J. Clauw², Richard E. Harris¹, Steven E. Harte¹, Anson E. Kairys³, Steven Buyske⁴ and David A. Williams⁵, ¹Anesthesiology, University of Michigan, Ann Arbor, MI, ²Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI, ³Department of Anesthesiology, Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, ⁴Statistics, Rutgers University, Piscataway, NJ, ⁵Chronic Pain & Fatigue Rsch Ctr, Univ of MI Hlth System-Lobby M, Ann Arbor, MI
Background/Purpose: Telomere length is considered a marker of cellular aging and has been linked to an increased risk for morbidity and mortality. Psychosocial factors associated…
Abstract Number: 867 • 2012 ACR/ARHP Annual Meeting
Events That Trigger the Onset of the Fibromyalgia Syndrome (FMS)
Robert S. Katz¹, Sharon M. Ferbert², Alexandra Small³ and Susan Shott¹, ¹Rush University Medical Center, Chicago, IL, ²Advocates for Funding Fibromyalgia Treatment, Education and Research(AFFTER), Libertyville, IL, ³University of Illinois Medical School, Chicago, IL
Background/Purpose: Triggering events – those that are followed by the onset or rapid increase in FMS symptoms – have a significant impact in some cases. …
Abstract Number: 868 • 2012 ACR/ARHP Annual Meeting
Illness Perceptions Among Patients with Different Forms of Vasculitis
Peter C. Grayson¹, Naomi Amudala², Carol McAlear³, Renée Leduc⁴, Denise Shereff⁵, Rachel Richesson⁶, Liana Fraenkel⁷ and Peter A. Merkel⁸, ¹Section of Rheumatology & the Clinical Epidemiology Unit, Boston University School of Medicine, Vasculitis Center, Boston, MA, ²Rheumatology & Vasculitis, Boston University Medical Center, Boston, MA, ³Vasculitis Clinical Research Consortium, University of Pennsylvania, Philadelphia, PA, ⁴Pediatrics Epidemiology Center, University of South Florida, Tampa, FL, ⁵Division of Bioinformatics and Biostatistics, University of South Florida, Tampa, FL, ⁶Epidemiology & Biostatistics, University of South Florida, Tampa, FL, ⁷Medicine, Section of Rheumatology, Yale University School of Medicine, Veterans Affairs Connecticut Healthcare System, New Haven, CT, ⁸University of Pennsylvania, Philadelphia, PA
Background/Purpose: Patient-held beliefs about their illness are central for understanding patient reactions to specific diseases. This study aimed to compare illness perceptions, defined as the…
Abstract Number: 869 • 2012 ACR/ARHP Annual Meeting
Concepts Which Determine Health in a Positive Way Are Important to People with Rheumatoid Arthritis and Are Covered by Some Patient-Reported Outcome Instruments
Mona Dür¹, Michaela Coenen², Josef S. Smolen³ and Tanja A. Stamm⁴, ¹Internal Medicine III Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ²Department of Medical lnformatics, Biometry and Epidemiology, Research Unit for Biopsychosocial Health, Ludwig-Maximilians-University, Munich, Germany, ³Division of Rheumatology, Department of Internal Medicine III,, Medical University of Vienna and Hietzing Hospital, Vienna, Austria, ⁴Rheumatology, Medical University of Vienna, Vienna, Austria
Background/Purpose: Rheumatoid arthritis is a chronic autoimmune disease that has a major impact on functioning, health and well-being. Concepts which determine health in a positive…
Abstract Number: 870 • 2012 ACR/ARHP Annual Meeting
To Love and to Hold: Men Describe Parenting in the Presence of Inflammatory Arthritis
Catherine L. Backman¹ and Alana Longson², ¹Occupational Science & Occupational Therapy, The University of British Columbia, Vancouver, BC, Canada, ²Arthritis Research Centre of Canada, Vancouver, BC, Canada
Background/Purpose: Inflammatory arthritis (IA) may limit participation in life roles such as parenting. Surprisingly little research has investigated the impact of IA on parenting tasks…
Abstract Number: 871 • 2012 ACR/ARHP Annual Meeting
Depression Predicts Mortality in RA
Christina Bode¹, Chris Tonner², Laura Trupin³ and Patricia P. Katz⁴, ¹Faculty of Behavioral Sciences, University of Twente, Enschede, Netherlands, ²Medicine, UCSF, San Francisco, CA, ³Medicine, University of California, San Francisco, San Francisco, CA, ⁴Medicine, University of California San Francisco, San Francisco, CA
Background/Purpose: Depression rates are elevated among individuals with rheumatoid arthritis (RA). Studies in cardiovascular disease and among elderly populations have found that depression is…
Abstract Number: 872 • 2012 ACR/ARHP Annual Meeting
Monocyte Chemoattractant Protein-1 and Eotaxin Are Associated with Parameters of Cardiac Dysfunction in Juvenile Dermatomyositis
Thomas Schwartz¹, Ivar Sjaastad², Berit Flatø³, Maria Vistnes¹, Geir Christensen¹ and Helga Sanner³, ¹Institute for Experimental Medical Research, Institute for Clinical Medicine, University of Oslo, Oslo, Norway, ²Institute for Clinical Medicine, University of Oslo, Institute for Experimental Medical Research, Oslo University Hospital, Oslo, Norway, ³Department of Rheumatology, Oslo University Hospital, Institute for Clinical Medicine, University of Oslo, Oslo, Norway
Background/Purpose : Juvenile dermatomyositis (JDM) is a vasculopathic disease affecting not only skeletal muscle and skin, but other organs as well. Previously we have shown…
Abstract Number: 833 • 2012 ACR/ARHP Annual Meeting
A Phase 1, Randomized, Double-Blind, Placebo-Controlled Multiple-Dose Study of Intravenous Staphylococcal Protein A in Patients with Active Rheumatoid Arthritis On Methotrexate: Safety, Pharmacokinetics and Efficacy
Edward Bernton¹, Eduard Krantz² and William Gannon Jr.³, ¹Protalex Inc., Summit, NJ, ²Parexel Clinical Pharmacology, Bloemfontein, South Africa, ³Capital City Technical Consulting, Inc., Washington, DC
Background/Purpose: PRTX-100 is highly-purified GMP staphylococcal protein A (SpA) that binds with extremely high affinity to the Vh antibody framework region of Clade Vh3 immunoglobulins. …
Abstract Number: 834 • 2012 ACR/ARHP Annual Meeting
Cetrorelix, a Gonadotropin-Releasing Hormone Antagonist, Significantly Reduces Tumour-Necrosis-Factor-Alpha and Demonstrates Efficacy in Patients with Active Rheumatoid Arthritis: A Proof-of-Concept, Double-Blind, Randomised Trial
Anita Kåss¹, Øystein T. Førre², Morten Fagerland³, Hans Christian Gulseth⁴, Peter Torjesen⁵ and Ivana Hollan⁶, ¹University of Oslo, Oslo, Norway, ²Oslo University Hospital, Oslo, Norway, ³Department of Biostatistics, Oslo University Hospital, Oslo, Norway, ⁴Rheumatology, Betanien Hospital, Skien, Norway, ⁵Department of Endocrinology, Oslo University Hospital, Oslo, Norway, ⁶Rheumatology, Lillehammer Hospital for Rheumatic Diseases, Lillehammer, Norway
Background/Purpose: The pathogenesis of rheumatoid arthritis (RA) is unclear, and treatment options can be improved. Gonadotropin-releasing hormone (GnRH) stimulates immune responses (1) and therefore might…
Abstract Number: 835 • 2012 ACR/ARHP Annual Meeting
Low Doses of Ocaratuzumab, a Fc- and Fab-Engineered Anti-CD20 Antibody, Result in Rapid and Sustained Depletion of Circulating B-Cells in Rheumatoid Arthritis Patients
Adrienne O'Reilly, Tracy Davis and Vinay Jain, Mentrik Biotech, Dallas, TX
Background/Purpose: B-cell depletion provides therapeutic benefits for patients with rheumatoid arthritis (RA). Ocaratuzumab, previously known as AME-133v, is a Fc- and Fab-engineered, humanized, anti-CD20…

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