ACR Meeting Abstracts

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  • Abstract Number: 1289 • ACR Convergence 2023

    Increases in Serum Levels of Tartrate-Resistant Acid Phosphatase 5b Reflected Radiographic Progression of Joint Damage in Treated Rheumatoid Arthritis

    Takayoshi Owada1, Takayuki Kobayashi1, Ayae Tanaka2, Kei Ikeda2, Hirokuni Hirata1, Masafumi Arima3, Kazuhiro Kurasawa2 and Yasutsugu Fukushima1, 1Dokkyo Medical University Saitama Medical Center, Koshigaya, Japan, 2Dokkyo Medical University, Mibu-machi, Shimotsuga-gun, Japan, 3Dokkyo Medical University, Koshigaya, Japan

    Background/Purpose: Rheumatoid Arthritis (RA) is one of inflammatory arthritis, and this autoimmune-mediated polyarthritis results in structural joint destruction. Articular bone erosion leading to joint destruction in RA…
  • Abstract Number: 1260 • ACR Convergence 2023

    Optimal Approaches for Reducing Depressive Symptoms in Rheumatoid Arthritis Patients Based on Psychological Interventions: A Systematic Review and Network Meta-analysis

    Zhang Lijuan and Wu Beiwen, Shanghai Jiao Tong University School of Medicine, Shanghai, China

    Background/Purpose: In recent years, numerous psychological interventions for rheumatoid arthritis (RA) patients have been developed. However, it remains unclear which psychological interventions are effective and…
  • Abstract Number: 0797 • ACR Convergence 2023

    Innate Lymphoid Cells Enhance Development of CD4+ T-cell Driven Autoimmune Arthritis

    Agnieszka Lastowska1, Charlotte E. van der Plas1, Anders Nguyen1, Symeon Kourmoulakis1, Miriam Bollmann1 and Mattias N.D Svensson2, 1Department of Rheumatology and Inflammation research, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 2University of Gothenburg, Gothenburg, Sweden

    Background/Purpose: Innate Lymphoid cells (ILCs) are innate counterparts to T-cells that, based on their functional phenotype, can be divided into three subpopulations called Group 1…
  • Abstract Number: 1115 • ACR Convergence 2023

    EULAR Recommendations for the Use of Imaging in the Diagnosis and Management of Crystal-induced Arthropathies in Clinical Practice

    Peter Mandl1, Maria-Antonietta D'Agostino2, Victoria Navarro-Compán3, Irina Gessl1, Garifallia Sakellariou4, Abhishek Abhishek5, Fabio Becce6, Nicola Dalbeth7, Hang-Korng Ea8, Emilio Filippucci9, Hilde Berner Hammer10, Annamaria Iagnocco11, Annette De Thurah12, Esperanza Naredo13, Sebastien Ottaviani14, Tristan Pascart15, Fernando Perez-Ruiz16, Irene Pitsillidou17, Fabian Proft18, Juergen Rech19, Wolfgang Schmidt20, Luca Sconfienza21, Lene Terslev22, Brigitte Wildner23, Pascal Zufferey24 and Georgios Filippou25, 1Department of Rheumatology, Medical University of Vienna, Vienna, Austria, 2Universita Cattolica del Sacro Cuore Rome, Courbevoie, France, 3Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain, 4Department of Internal Medicine and Therapeutics, Università di Pavia, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy, 5University of Nottingham, Nottingham, United Kingdom, 6Lausanne University Hospital (CHUV), Lausanne, Switzerland, 7University of Auckland, Auckland, New Zealand, 8Hôpital Lariboisière, APHP-Nord, Service de Rhumatologie, Université de Paris Cité, Paris, France, 9Polytechnic University of Marche, Jesi, Italy, 10Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway AND University of Oslo, Faculty of Medicine, Oslo, Norway, 11University of Turin, Roma, Italy, 12Aarhus University Hospital, Aarhus, Denmark, 13Hospital Fundación, Madrid, Spain, 14Assistance Publique Hopitaux de Paris, Paris, France, 15Department of Rheumatology, Saint-Philibert Hospital, Lille Catholic University, Lille, France, 16Rheumatology Division, Osakidetza, OSI-EE Cruces, Cruces University Hospital, Barakaldo, Spain, 17EULAR Patient Research Partner, Executive Secretary of Cyprus League Against Rheumatism, Nicosia, Cyprus, 18Department of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, 19University Clinic Erlangen, Erlangen, Germany, 20Rheumatology, Immanuel Krankenhaus Berlin, Medical Centre for Rheumatology Berlin-Buch, Berlin, Germany, 21Dipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano AND IRCCS Istituto Ortopedico Galeazzi, 20161, Milan, Italy, 22Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, 23University Library, Medical University of Vienna, Vienna, Austria, 24Rheumatology Department, University of Lausanne, CHUV, Lausenne, Switzerland, 25IRCCS Galeazzi - Sant'Ambrogio Hospital, Milan, Italy

    Background/Purpose: The multifaceted clinical presentation in crystal-induced arthropathies (CiA) poses challenges to imaging. Our goal was to formulate evidence-based recommendations on the use of imaging…
  • Abstract Number: 1106 • ACR Convergence 2023

    Monosodium Urate and Calcium Pyrophosphate Crystal-induced Inflammation Relies on Cell Volume Regulation and LRRC8/VRAC Channel Activation

    Twinu Wilson Chirayath1, mete kayatekin2, Isabelle Rubera3, Nghia Pham4, FREDERIC LIOTE4, Pascal Richette5, Vincent COMPAN6, François Rassendren7, Christophe Duranton3 and Hang Korng EA4, 1INSERM, Paris, France, 2CNRS-UMR7370, Nice, France, 3CNRS-UMR 7370, Nice, France, 4INSERM-BIOSCAR, Paris, France, 5Lariboisière Hospital, Paris, France, 6CNRS-IGF, Montpellier, France, 7CNRS UMR 5203, Montpellier, France

    Background/Purpose: Monosodium urate (MSU) and calcium pyrophosphate (CPP) crystals are responsible for interleukin (IL)-1β dependent acute arthritis. The release of mature IL-1β is dependent on…
  • Abstract Number: 1131 • ACR Convergence 2023

    Clinical Phenotypes of IgG4-related Disease in a Multi-ethnic Singapore Cohort

    Choon Guan Chua1, Weida Chew1, Jeggrey Kay Wee Kam1, Hwee-Pin Phua1, Chengzi Chow1, Carol Yee-Leng Ng1, Wei-Yen Lim1, Ru Sin Lim1, Jereme Yijin Gan1, Mung-Ee Loh1, Tianrong Yeo2, David Zhiwei Law1, Stephrene Seok Wei Chan3, Amanda Francesca Ya-Fang Cheang4, Yong-Howe Ho1 and Charles Kien-Fong Vu1, 1Tan Tock Seng Hospital, Singapore, Singapore, 2National Neurology Institute, Singapore, Singapore, 3National University Hospital, Singapore, Singapore, 4Woodlands Health Campus, Singapore, Singapore

    Background/Purpose: IgG4-related disease (IgG4-RD) is an immune-mediated condition that is heterogenous and can result in organ failure. To understand the disease profile of our local…
  • Abstract Number: 1268 • ACR Convergence 2023

    Clinical Characteristics of Patients with Rheumatoid Arthritis (RA) Who Rate Their Global Assessment of Disease Activity Substantially Lower Than Their Physicians (Negative Discordance) Based on a Large RA Database in Japan: A Rare but Important Subgroup

    Tetsuji Sawada1, Susumu Nishiyama2, Shohei Yamashita3, Toshihiro Matsui4 and Shigeto Tohma5, 1Tokyo Medical University Hospital, Shinjuku Tokyo, Japan, 2Kurashiki Medical Center, Kurashiki, Japan, 3Tokyo Medical University Hospital, Shinjuku, Japan, 4NHO Sagamihara National Hospital, Kanagawa, Japan, 5NHO Tokyo National Hospital, Dallas, TX

    Background/Purpose: Discordance between patient global assessment (PGA) and physician global assessment (PhGA) regarding the disease activity of rheumatoid arthritis (RA) can be divided into three…
  • Abstract Number: 1128 • ACR Convergence 2023

    Refractory Inflammatory Ocular Pathology and Treatment with Janus Kinase Inhibitors. Multicenter Study and Literature Review

    Carmen Lasa-Teja1, Lara Sanchez-Bilbao2, Jose Luis Martin-Varillas3, Vanesa Calvo Río4, José Luis Álvarez-Vega5, Emma Beltran-Catalan6, María del Mar Esteban-Ortega7, Santiago Muñoz7, Olga Maiz8, Ignacio Torre-Salaberri9, Ana Urruticoechea10, Elia Valls-Pascual11, Raúl Veroz12, Carmen Alvarez Reguera13, Rosalía Demetrio13 and Ricardo Blanco14, 1Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology Group, Santander, Spain, 2Hospital Universitario Marques de Valdecilla, Santander, Spain, 3Hospital de Laredo, Laredo, Spain, 4Valdecilla Hospital, Santander, Spain, 5Complejo Hospitalario Universitario de Badajoz, Badajoz, Spain, 6HOSPITAL DEL MAR, Barcelona, Spain, 7Hospital Infanta Sofia, Madrid, Spain, 8Hospital Universitario de Donostia. San Sebastián, Spain., Donosti, Spain, 9Hospital Universitario de Basurto, Bilbao, Spain, 10Hospital Can Misses, Ibiza, Spain, 11Hospital Universitario Doctor Peset. Alicante, Spain., Valencia, Spain, 12Hospital de Mérida, Mérida. Spain., Mérida, Spain, 13Hospital Universitario Marqués de Valdecilla, Santander, Spain, 14Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: Inflammatory ocular pathology (IOP) includes internal (uveitis) and external [mainly ocular surface pathology such as epi/scleritis and peripheral ulcerative keratitis (PUK)] involvement. IOP may…
  • Abstract Number: 0986 • ACR Convergence 2023

    Medication Use Patterns and Factors Associated with Abnormal Pregnancy Outcomes in Patients with Rheumatoid Arthritis in Korea

    Yeo-Jin Song1, Soo-Kyung Cho1, Yu-Seon Jung2, Jihyun Keum3, Sun-Young Jung2, Dae Hyun Yoo4 and Yoon-Kyoung Sung1, 1Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 2College of Pharmacy, Chung-Ang University, Seoul, South Korea, 3Department of Obstetrics and Gynecology, College of Medicine, Hanyang University, Seoul, South Korea, 4Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea

    Background/Purpose: As female patients constitute a significant proportion of rheumatoid arthritis (RA) cases, pregnancy management is crucial for women with RA. This study aimed to…
  • Abstract Number: 0990 • ACR Convergence 2023

    Association of Treatment and Disease Activity with Antibiotic Use and Hospitalized Infection Among People Living with Rheumatoid Arthritis: Baseline Data from a Longitudinal Study in the ArthritisPower Registry

    Kelly Gavigan1, Esteban Rivera2, Odette Kolenky3, Cassie Clinton4, Emily Holladay4, David Curtis5, Laura Stradford6, Jeffrey Curtis4, W. Benjamin Nowell6, Christian Curtis7 and Michael George8, 1Global Healthy Living Foundation, Upper Nyack, NY, 2Global Healthy Living Foundation, Long Island City, NY, 3Hospital of the University of Pennsylvania, Philadelphia, PA, 4University of Alabama at Birmingham, Birmingham, AL, 5Global Healthy Living Foundation, San Francisco, CA, 6Global Healthy Living Foundation, Nyack, NY, 7Illumination Health, Birmingham, AL, 8University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Infections are a major contributor to morbidity and mortality in patients (pts) with rheumatoid arthritis (RA). Little is known about the risk of non-serious…
  • Abstract Number: 1263 • ACR Convergence 2023

    Depression and Anxiety Risk Assessment in Patients with Rheumatic Diseases

    Luis Vega Sevilla1, Miguel Villarreal-Alarcon2, Diana Paola Flores-Gutierrez3, Maria Corral-Trujillo4, Ricardo Juarez4, Ivan Hernandez Galarza5, Jesus Alberto Cardenas-De la Garza6 and Dionicio A. Galarza-Delgado2, 1Hospital Universitario UANL, Garcia, Mexico, 2Hospital Universitario UANL, Monterrey, Mexico, 3Hospital Universitario "Dr. José Eleuterio González", Monterrey, Mexico, 4Universidad Autónoma de Nuevo León, Monterrey, Mexico, 5University Hospital, UANL, San Pedro Garza Garcia, Mexico, 6Hospital Universitario "Dr. José Eleuterio González", San Nicolas, Mexico

    Background/Purpose: Depression is one of the most common psychiatric comorbidities in patients with rheumatic diseases. A study has shown that almost a third of patients…
  • Abstract Number: 0362 • ACR Convergence 2023

    Adverse Childhood Experiences Are Associated with Disease Outcomes in Youth with Juvenile Idiopathic Arthritis

    Danielle Bullock1, Ilir Agalliu2, Evin Rothschild2, Kaveh Ardalan3, Erica Lawson4, Natoshia Cunningham5, William Soulsby4, Nicole Reitz6, Laura Bouslaugh7, Anna Diggs8, Elizabeth Kessler9, Sara Kramer1, Bhupinder Nahal4, Cassandra Davis10, Ashley Kemp1, Riley O'Connor1, Tiffany Chinn4, Kathy Nguyen4, Paige Hill1 and Tamar Rubinstein11, 1University of Minnesota, Minneapolis, MN, 2Albert Einstein College of Medicine, Bronx, NY, 3Duke University School of Medicine, Durham, NC, 4University of California San Francisco, San Francisco, CA, 5Michigan State University, Grand Rapids, MI, 6CARRA, Allendale, MI, 7CARRA, Washington, DC, 8CARRA, Tipton, MO, 9Spectrum Health, Grand Rapids, MI, 10University of Utah, Salt Lake City, UT, 11Albert Einstein College of Medicine, Children's Hospital at Montefiore, White Plains, NY

    Background/Purpose: Adverse childhood events (ACEs) are common in children. ACEs are various stressors, including, but not limited to parental incarceration or food and housing insecurity.…
  • Abstract Number: 1270 • ACR Convergence 2023

    Identification of Subclinical Atherosclerosis by Six Cardiovascular Risk Calculators in Rheumatoid Arthritis Patients

    Natalia Guajardo-Jauregui1, José Ramón Azpiri-López2, Dionicio A. Galarza-Delgado2, Iris Colunga2, Jesus Alberto Cardenas-De la Garza3 and Rosa Arvizu-Rivera4, 1Hospital Universitario Dr. José Eleuterio González, Monterrey, Mexico, 2Hospital Universitario UANL, Monterrey, Mexico, 3Hospital Universitario "Dr. José Eleuterio González", San Nicolas, Mexico, 4Hospital Universitario "Dr. José Eleuterio Gonzalez", Escobedo, Mexico

    Background/Purpose: Current EULAR recommendations for cardiovascular risk (CVR) assessment in rheumatoid arthritis (RA) patients indicate that the CVR evaluation should be performed according to national…
  • Abstract Number: 1269 • ACR Convergence 2023

    The Impact of Sex, Serostatus, and Smoking on Risk for Rheumatoid Arthritis-associated Interstitial Lung Disease Subtypes

    Gregory McDermott1, Keigo Hayashi1, Pierre-Antoine Juge2, Ritu Gill1, Suzanne Byrne1, Staci Gagne1, Kathleen Vanni1, Emily Kowalski1, Grace Qian1, Katarina Bade3, Alene Saavedra1, Yumeko Kawano1, Michael Diiorio3, Taylor Wolfgang1, Edy Kim1, Paul Dellaripa3, Michael Weinblatt4, Nancy Shadick3, Tracy J. Doyle1 and Jeffrey Sparks5, 1Brigham and Women's Hospital, Boston, MA, 2Division of Rheumatology, Inflammation, and Immunity Brigham & Women's Hospital, Boston, MA, 3Brigham and Women's Hospital, Boston, MA, 4Harvard Medical School, Waban, MA, 5Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: RA-associated interstitial lung disease (RA-ILD) is a heterogenous condition encompassing multiple subtypes with varying histopathology, prognosis, and potential treatment options. The most common RA-ILD…
  • Abstract Number: 1141 • ACR Convergence 2023

    COVID-19 Vaccination Status and Adverse Events Following SARS-CoV-2 Vaccine in Autoimmune Inflammatory Rheumatic Disease (AIRD) Patients: A Single Center Experience

    Vincent Luceño1, Peter Paolo Daleon1 and Sandra Navarra2, 1University of Santo Tomas Hospital, City of Manila, Philippines, 2University of Santo Tomas Hospital, Joint and Bone Center, Manila, Philippines

    Background/Purpose: Autoimmune inflammatory rheumatic diseases (AIRD) were associated with an increased risk for COVID-19 infection, worse clinical outcomes, and COVID-19- related deaths. Vaccines carry the…
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