Abstracts Archive - Page 2509 of 2607 - ACR Meeting Abstracts

Abstract Number: 1429 • 2012 ACR/ARHP Annual Meeting
Women with Systemic Lupus Erythematosus (SLE) May Have Different Predictors of Risk for Progression of Aorta Calcium (AS) Than Women without SLE
Apinya Lertratanakul¹, Peggy W. Wu², Alan Dyer¹, William Pearce¹, George Kondos³, Daniel Edmundowicz⁴, James Carr⁵ and Rosalind Ramsey-Goldman⁶, ¹Northwestern University, Chicago, IL, ²Rheumatology, Northwestern University, Chicago, IL, ³University of Illinois at Chicago, Chicago, IL, ⁴Temple University School of Medicine, Philadelphia, PA, ⁵Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Medicine/Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Women with SLE have increased rates of subclinical atherosclerosis and cardiovascular (CV) events. We investigated which risk factors may be significant in the rate…
Abstract Number: 1430 • 2012 ACR/ARHP Annual Meeting
Women with Systemic Lupus Erythematosus (SLE) May Have Different Predictors of Risk for Progression of Coronary Artery Calcium (CAC)Than Women without SLE
Apinya Lertratanakul¹, Peggy W. Wu², Alan Dyer¹, William Pearce¹, George Kondos³, Daniel Edmundowicz⁴, James Carr⁵ and Rosalind Ramsey-Goldman⁶, ¹Northwestern University, Chicago, IL, ²Rheumatology, Northwestern University, Chicago, IL, ³University of Illinois at Chicago, Chicago, IL, ⁴Temple University School of Medicine, Philadelphia, PA, ⁵Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Medicine/Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Women with SLE have increased rates of subclinical atherosclerosis and cardiovascular (CV) events. We sought to determine which risk factors may be significant in…
Abstract Number: 1431 • 2012 ACR/ARHP Annual Meeting
Single Photon Emission Computed Tomography Contributes to Clinical Assessments in Neuropsychiatric Systemic Lupus Erythematosus Patients
Maasa Hama¹, Mitsuhiro Takeno¹, Atsushi Ihata¹, Daiga Kishimoto¹, Reikou Watanabe¹, Takeaki Uehara², Ryusuke Yoshimi¹, Yukiko Asami¹, Atsuhisa Ueda¹ and Yoshiaki Ishigatsubo¹, ¹Department of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan, ²Department of Rheumatology, Chigasaki Municipal Hospital, Chigasaki, Japan
Background/Purpose: Because the clinical manifestations of NPSLE are diverse, multifaceted approaches are necessary to evaluate the disease activity and therapeutic responses. We investigated contribution of…
Abstract Number: 1432 • 2012 ACR/ARHP Annual Meeting
Safety and Efficacy of Etanercept in Systemic LUPUS Erythematosus
Josefina Cortes-Hernandez¹, Natalia Egri¹, Miquel Vilardell-Tarres¹ and Josep Ordi-Ros², ¹Medicine Department. Systemic Autoimmune Diseases Unit, Hospital Universitari Vall dxHebron, Institut de Recerca (VHIR),, Barcelona, Spain, ²Internal Medicine, Vall De Hebron General Hospt, Barcelona, Spain
Background/Purpose: TNF is a strong mediator of inflammation with a controversial role in SLE. Whereas few open-label studies have shown efficacy of anti-TNFα agents in…
Abstract Number: 1433 • 2012 ACR/ARHP Annual Meeting
Persistent Dyslipidemia Is a Risk Factor of Progression to Chronic Kidney Disease in Patients with Lupus Nephritis
Dong-Jin Park¹, Kyung-Eun Lee¹, Tae-Jong Kim¹, Yong-Wook Park¹ and Shin-Seok Lee², ¹Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, ²Dept of Int Med/Rheumatology, Chonnam National University Medical School, Gwangju, South Korea
Background/Purpose: To investigate the effect of dyslipidemia at baseline and during follow-up period on the progression to chronic kidney disease (CKD) in patients with biopsy-proven…
Abstract Number: 1434 • 2012 ACR/ARHP Annual Meeting
Cardiovascular Morbidity in a Long-Term Follow-up Cohort of Systemic Lupus Erythematosus Patients in Southern Sweden
Ragnar Ingvarsson¹, Ola Nived², Gunnar Sturfelt³, Anders Bengtsson⁴ and Andreas Jönsen⁵, ¹Department of Clinical Sciences Lund, Section of Rheumatology, Lund, Sweden, ²Department of Clinical Science, Lund University, Rheumatology, Lund, Sweden, ³Department of Clinical Sciences Lund, Section of Rheumatology, Lund University, Lund, Sweden, ⁴Department of Rheumatology, University Hospital Lund, Lund, Sweden, ⁵Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund, Sweden
Background/Purpose: The main objective was to study the incidence of myocardial infarction in a cohort of patients with Systemic Lupus Erythematosus (SLE) assembled prospectively over…
Abstract Number: 1435 • 2012 ACR/ARHP Annual Meeting
Identifying Systemic Lupus Erythematosus Patients At Higher Risk of Coronary Artery Disease
Dominique Ibanez¹, D. D. Gladman² and Murray B. Urowitz¹, ¹Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada
Background/Purpose: There is a high prevalence of premature atherosclerosis among patients with SLE. The traditional Framingham risk score (FRS) identifies few of the SLE patients…
Abstract Number: 1396 • 2012 ACR/ARHP Annual Meeting
Associates of a History of Thrombosis in Systemic Lupus Erythematosus
Melissa Nastacio¹, Hong Fang², Thomas Kickler², Jayesh Jani², Laurence S. Magder³ and Michelle Petri², ¹Div of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ²Johns Hopkins University School of Medicine, Baltimore, MD, ³Department of Epidemiology and Public Health, University of Maryland, Baltimore, MD
Background/Purpose: Thrombosis in SLE is highly associated with antiphospholipid antibodies, yet the majority of those with antiphospholipid antibodies never have a thrombotic event. Plasma microparticles…
Abstract Number: 1397 • 2012 ACR/ARHP Annual Meeting
Risk Factors Associated with Early Central Nervous System Damage Detected Through Perfusion MRI in Patients with Systemic Lupus Erythematosus
Paola Tomietto¹, Federica Casagrande², Maja Ukmar², Luca Weis², Pia Morassi¹, Rita Moretti³, Gianni Biolo³, Carlo Giansante³ and Maria Assunta Cova², ¹Internal Medicine Department, AOU Ospedali Riuniti di Trieste, Trieste, Italy, ²Radiology Department, Radiology Department, University of Trieste, Trieste, Italy, ³Internal Medicine Department, Internal Medicine Department, University of Trieste, Trieste, Italy
Background/Purpose: Antiphospholipid antibodies (aPL), hypertension and accumulated damage (SLICC-DI) have been associated to the severity of cerebral MRI lesions and to cognitive deficits in SLE.…
Abstract Number: 1398 • 2012 ACR/ARHP Annual Meeting
Inflammatory Back Pain Is Increased in SLE and Associated with Anti-Sm Antibodies
Neslihan Yilmaz¹, Ayten Yazici², Sibel Z. Aydin³ and Sule Yavuz⁴, ¹Rheumatology, Marmara University, Faculty of Medicine, Istanbul, Turkey, ²Department of Rheumatology, Sakarya Research and Training Hospital, Sakarya, Turkey, ³Unit of Rheumatology, Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey, ⁴Rheumatology, Bilim University, Faculty of Medicine, Rheumatology Department, Istanbul, Turkey
Background/Purpose: Growing evidence suggest that autoantibodies may present in patients with ankylosing spondylitis. Here, we aim to determine the association of inflammatory back pain and…
Abstract Number: 1399 • 2012 ACR/ARHP Annual Meeting
Regional Fat Distribution Is Independently Associated with Damage Accrual in Systemic Lupus Erythematosus Female Patients
Manuel F. Ugarte-Gil¹, Rocio V. Gamboa-Cardenas², Karim E. Diaz-Deza², Mariela Medina-Chinchon¹, J. Mariano Cucho-Venegas¹, Risto A. Perich-Campos¹, Jose L. Alfaro-Lozano¹, Alfredo A. Sanchez-Torres², Zoila Rodriguez-Bellido¹, Sheyla Rodriguez-Ulloa² and Cesar A. Pastor-Asurza¹, ¹Rheumatology, Hospital Guillermo Almenara, EsSalud, Lima, Peru, ²Rheumatology, Hospital Almenara, Lima, Peru
Background/Purpose: In general population, a higher trunk fat and the ratio of trunk fat to leg fat (trunk-leg ratio) increase the risk for a cardiovascular…
Abstract Number: 1400 • 2012 ACR/ARHP Annual Meeting
Predictors of Obesity in Systemic Lupus Erythematosus
Michelle Petri¹, Sesha Adusumilli² and Hong Fang¹, ¹Johns Hopkins University School of Medicine, Baltimore, MD, ²Div of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: Hypertension and obesity are the two most important traditional cardiovascular risk factors in the prediction of subclinical measures of atherosclerosis in SLE. Obesity is…
Abstract Number: 1401 • 2012 ACR/ARHP Annual Meeting
Characterization of Clinical Photosensitivity in Cutaneous Lupus Erythematosus
Kristen Foering¹, Aileen Y. Chang², Evan W. Piette², Joyce Okawa³ and Victoria P. Werth⁴, ¹Dermatology, University of Pennsylvania, Philadelphia VAMC, Philadelphia, PA, ²Dermatology/2nd Fl, University of Pennsylvania, Philadelphia, PA, ³Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania and Philadelphia V.A. Medical Center, Philadelphia, PA, ⁴Department of Dermatology, Veteran Affairs Medical Center, Philadelphia, PA
Background/Purpose: Photosensitivity (PS) is one of the most common manifestations of systemic lupus erythematosus (SLE), and is 1 of only 11 criteria used to make…
Abstract Number: 1402 • 2012 ACR/ARHP Annual Meeting
Anti-ApoA1 Antibodies Associate with Disease Activity in Lupus and Are Lower in Patients Taking Hydroxychloroquine: A Longitudinal Analysis of 398 Samples
Sara Croca¹, Ian Giles², David A. Isenberg³, Yiannis Ioannou⁴ and Anisur Rahman², ¹Centre for Rheumatology Research, Division of Medicine, University College London, London, United Kingdom, ²Centre for Rheumatology Research,Rayne Institute, 4th Floor, University College London, London, United Kingdom, ³Centre for Rheumatology Research, Rayne Building, 4th Floor, Centre for Rheumatology, Department of Medicine, University College London, London, United Kingdom, ⁴Arthritis Research UK Centre for Adolescent Rheumatology at University College London, Great Ormond Street Hospital and UCLH, University College London, London, United Kingdom
Background/Purpose: Patients with systemic lupus erythematosus (SLE) have a significantly increased risk of developing cardiovascular disease. The presence of chronic inflammation which characterizes SLE…
Abstract Number: 1403 • 2012 ACR/ARHP Annual Meeting
Anti-Nucleosome Antibodies Are Associated with Disease Activity and Hydroxychloroquine Use in Patients with Lupus: A Longitudinal, Multivariate Analysis of 398 Samples
Sara Croca¹, Ian Giles², David A. Isenberg³, Yiannis Ioannou⁴ and Anisur Rahman², ¹Centre for Rheumatology Research, Division of Medicine, University College London, London, United Kingdom, ²Centre for Rheumatology Research,Rayne Institute, 4th Floor, University College London, London, United Kingdom, ³Centre for Rheumatology Research, Rayne Building, 4th Floor, Centre for Rheumatology, Department of Medicine, University College London, London, United Kingdom, ⁴Arthritis Research UK Centre for Adolescent Rheumatology at University College London, Great Ormond Street Hospital and UCLH, University College London, London, United Kingdom
Background/Purpose: Impaired apoptotic clearance appears to play a pivotal role in the pathogenesis of SLE leading to the accumulation of nuclear debris, such as nucleosomes,…

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