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  • Abstract Number: 2367 • 2012 ACR/ARHP Annual Meeting

    Presence of Fibromyalgia and Fatigue Is Not Increased in Patients with Takayasu’s Arteritis

    Fatma Alibaz-Oner1, Meryem Can1, Birkan Ilhan2, Ozge Polat2 and Haner Direskeneli1, 1Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, 2Internal Medicine, Marmara University, School of Medicine, Istanbul, Turkey

    Background/Purpose: Takayasu’s arteritis (TAK) is a large-vessel vasculitis of the aorta and its major branches. To our knowledge, no data is reported about the frequency…
  • Abstract Number: 2368 • 2012 ACR/ARHP Annual Meeting

    Tocilizumab in Refractory Takayasu’s Arteritis: 7 Patients Followed At a Single Italian Centre

    Enrico Tombetti1, Elena Baldissera2, Stefano Franchini1, Patrizia Aiello3, Francesca Motta1, Barbara Gulgielmi1 and Maria Grazia Sabbadini1, 1Internal Medicine and Clinical Immunology, Vita-Salute San Raffaele University, Milan, Italy, 2Vita-Salute San Raffaele University, Milano, Italy, 3Internal Medicine and Clinical Immunology, Ospedale San Raffaele and Università Vita-Salute San Raffaele, Milano, Italy

    Background/Purpose: Takayasu arteritis (TA) is a rare chronic-relapsing vasculitis involving primarily the aorta and its major branches.TA is associated with considerable morbidity and mortality. Therapy…
  • Abstract Number: 2369 • 2012 ACR/ARHP Annual Meeting

    Aspects of Innate Immunity in Behçet´s Disease: A Model of Autoinflammatory Disease?

    Sandro F. Perazzio1, Paulo Vitor Soeiro Pereira2, Alexandre Wagner S. de Souza3, Antonio Condino-Neto2 and Luis Eduardo C. Andrade4, 1Rheumatology, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil, 2Immunology, ICB IV - Universidade de São Paulo, São Paulo, Brazil, 3Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, 4Rheumatology Division, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil

    Background/Purpose: Behçet's disease (BD) is a systemic vasculitis of unknown etiopathogenesis. Increased neutrophil activation has been previously shown in BD patients and it is unclear…
  • Abstract Number: 2370 • 2012 ACR/ARHP Annual Meeting

    A Genome-Wide DNA Methylation Study Identifies Significant Epigenetic Changes Across the Genome and in Multiple HLA Loci in Behcet’s Disease

    Haner Direskeneli1, Patrick S. Coit2, Filiz Ture-Ozdemir1, Fatma Alibaz-Oner1, Guher Saruhan-Direskeneli3, Matlock A. Jeffries4 and Amr H. Sawalha2, 1Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, 2Division of Rheumatology, University of Michigan, Ann Arbor, MI, 3Department of Physiology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, 4Medicine, University of Oklahoma and Oklahoma Medical Research Foundation, Oklahoma City, OK

    Background/Purpose: Behcet’s disease (BD) is a systemic vasculitis of poorly understood etiology. Herein, we study the DNA methylome in BD for the first time and…
  • Abstract Number: 2371 • 2012 ACR/ARHP Annual Meeting

    The Unmet Need in Behcet’s Disease: Most Patients Are Not in Complete Remission in the Long-Term Follow-up

    Fatma Alibaz-Oner1, Gonca Mumcu2, Gülsen Ozen3, Zeynep Kubilay4, Meryem Can1, Sibel Yýlmaz Oner1, Tülin Ergun5 and Haner Direskeneli1, 1Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, 2Department of Health Management, Marmara University, Faculty of Health Sciences, Istanbul, Turkey, 3Rheumatology, Marmara University School of Medicine., Istanbul, Turkey, 4Internal Medicine, Marmara University, School of Medicine, Istanbul, Turkey, 5Dermatology, Marmara University School of Medicine, Istanbul, Turkey

    Background/Purpose: The nature of Behcet’s disease (BD) as a multi-systemic disorder with a remitting-relapsing course is unsufficiently explored. As complete remission should be aimed in…
  • Abstract Number: 2372 • 2012 ACR/ARHP Annual Meeting

    Efficacy of Quantitative Analysis of Brainstem Atrophy On Magnetic Resonance Imaging for Diagnosis of Chronic Progressive Neuro-Behçet’s Disease

    Hirotoshi Kikuchi1, Maki Takayama2, Yoshitaka Kimura2, Kurumi Asako2, Hajime Kono2, Yasuo Ono1 and Shunsei Hirohata3, 1Department of Microbiology and Immunology, Teikyo University Shool of Medicine, Tokyo, Japan, 2Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan, 3Int Med/Rheumatol & Infec Dis, Kitasato University School of Medicine, Sagamihara, Japan

    Background/Purpose : CNS involvement in Behçet's disease, usually called neuro-Behçet's disease (NB), can be classified into acute NB (ANB) and chronic progressive NB (CPNB) based…
  • Abstract Number: 2373 • 2012 ACR/ARHP Annual Meeting

    The Clinical Course of the Acute Deep Vein Thrombosis of the Legs in Behçet’s Syndrome

    Yesim Ozguler1, Melike Melikoglu2, Firat Cetinkaya3, Serdal Ugurlu4, Emire Seyahi5, Koray Tascilar6 and Hasan Yazici7, 1Cerrahpasa Medical Faculty, Istanbul University, Cerrahpasa Medical School, Rheumatology, Istanbul, Turkey, 2Cerrahpasa Medical Faculty, Rheumatology, Istanbul, Turkey, 3Radiology, Colormed Radiology Center, Istanbul, Turkey, 4Rheumatology, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey, 5Rheumatology, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey, 6University of Istanbul, Cerrahpasa Medical Faculty, Rheumatology, Istanbul, Turkey, 7Istanbul University, Cerrahpasa Medical School, Rheumatology, Istanbul, Turkey

    Background/Purpose: 15-50% of patients with Behçet’s syndrome have vascular involvement (BS). Deep vein thrombosis is the most common form with lower extremity deep vein thrombosis…
  • Abstract Number: 2374 • 2012 ACR/ARHP Annual Meeting

    Characteristics, Treatment and Outcome of Gastrointestinal Involvement in Behcet’s Syndrome: Experience in A Dedicated Center

    Ibrahim Hatemi1, Gulen Hatemi2, Yusuf Erzin1, Aykut Ferhat Celik1 and Hasan Yazici3, 1Istanbul University, Cerrahpasa Medical School, Istanbul University, Cerrahpasa Medical School, Gastroenterology, Istanbul, Turkey, 2Istanbul University, Cerrahpasa Medical Faculty, Istanbul University, Cerrahpasa Medical Faculty, Rheumatology, Istanbul, Turkey, 3Istanbul University, Cerrahpasa Medical School, Istanbul University, Cerrahpasa Medical School, Rheumatology, Istanbul, Turkey

    Background/Purpose: Gastrointestinal involvement can be a severe complication resulting in perforation and massive bleeding. Controlled data regarding treatment is lacking and long term prognosis is…
  • Abstract Number: 2375 • 2012 ACR/ARHP Annual Meeting

    WHAT Affects the Quality of Life in Patients with BEHCET’S Disease?

    Mehmet Melikoglu1 and Meltem Alkan Melikoglu2, 1Dermatology, Health Ministry Erzurum Regional Training and Research Hospital, Dermatology, Erzurum, Turkey, 2Rheumatology, Ataturk University Faculty of Medicine, Erzurum, Turkey

    Background/Purpose: The aim of this study was to evaluate the possible associations between quality of life (QoL) and sociodemographic features, disease characteristics and the Behcet’s…
  • Abstract Number: 2376 • 2012 ACR/ARHP Annual Meeting

    Behcet’s Disease: Combination of Pulse Cyclophosphamide, Azathioprine, and Prednisolone for the Treatment of Retinal Vasculitis; Longitudinal Study On 10 Years

    Fereydoun Davatchi1, Farhad Shahram2, Bahar Sadeghi Abdollahi2, Hormoz Shams2, Abdolhadi Nadji2, Massoomeh Akhlaghi2, Tahereh Faezi2 and Farimah Ashofteh2, 1Rheumatology Research Ctr and Department of Rheumatology, Shariati Hospital-Tehran Univ, Tehran, Iran, 2Rheumatology, Behcet's Unit, Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran

    Background/Purpose: Ocular lesions of Behcet’s Disease (BD), need aggressive treatment to prevent severe loss of vision or blindness. Cytotoxic drugs are the main therapeutic agents…
  • Abstract Number: 2377 • 2012 ACR/ARHP Annual Meeting

    Impaired Endothelial Function in Patients with Takayasu’s Arteritis

    Fatma Alibaz-Oner1, Selen Yurdakul2, Yelda Tayyareci3, Saide Aytekin4 and Haner Direskeneli1, 1Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, 2Cardiology, Bilim University, Faculty of Medicine, Cardiology Department, Istanbul, Turkey, 3Cardiology, ISTANBUL FLORENCE NIGHTINGALE HOSPITAL, Istanbul, Turkey, 4Cardiology, Istanbul Florence Nightingale Hospital, Cardiology, Istanbul, Turkey

    Background/Purpose: Takayasu’ s arteritis (TAK) is a chronic, inflammatory, large-vessel vasculitis. In the present study we aimed to evaluate vascular endothelial function in patients with…
  • Abstract Number: 2378 • 2012 ACR/ARHP Annual Meeting

    Evaluation of the EULAR/ACR 2012 Classification Criteria for Polymyalgia Rheumatica: Comparison of the New Algorithms with and without Ultrasound to the Formerly Used Criteria

    Sandra Balser1, Wolfgang Hartung2, Emmanuelle LeBras1, Boris P. Ehrenstein2, Martina Müller3 and Martin Fleck2, 1Rheumatology & Clinical Immunology, Asklepios Klinikum Bad Abbach, Bad Abbach, Germany, 2Rheumatology & Clinical Immunology, Asklepios Clinic Bad Abbach, Bad Abbach, Germany, 3Clinic for Internal Medicine I, University Clinic Regensburg, Regensburg

    Background/Purpose: The purpose of this study was to compare the sensitivity of the algorithms with and without ultrasound of the EULAR/ACR 2012 Classification Criteria for Polymyalgia…
  • Abstract Number: 2379 • 2012 ACR/ARHP Annual Meeting

    Successful Treatment of Churg-Strauss Syndrome with Rituximab

    Christin Dubrau1, Fabian Arndt2, Wolfgang L. Gross and Frank Moosig4, 1Departement of Rheumatology and Clinical Immunology, University Hospital Schleswig-Holstein, Campus Luebeck and Klinikum Bad Bramstedt, Bad Bramstedt, Germany, 2Departement of rheumatology and clinical immunology, University Hospital Schleswig Holstein and Klinikum Bad Bramstedt, Bad Bramstedt, Germany, 3Vasculitis Clinic, Klinikum Bad Bramstedt & University Hospital of Schleswig Holstein, Bad Bramstedt, Germany

    Background/Purpose: Rituximab has recently been shown to be equipotent to cyclophosphamide for induction of remission in generalized ANCA-associated vasculitis. A substantial number of observational pro-…
  • Abstract Number: 2380 • 2012 ACR/ARHP Annual Meeting

    High Frequency of Ferritin Autoantibodies in Takayasu Arteritis

    Niklas T. Baerlecken1, Katherina Große2, Frank Moosig3, Wolfgang L. Gross4, Reinhold E. Schmidt1 and Torsten Witte5, 1Clinical Immunology and Rheumatology, Medical University Hannover, Hannover, Germany, 2Department of Immunology and Rheumatology, Student, Hannover, Germany, 3University of Luebeck, Stormarnzing 156, Bad Bramstedt, Germany, 4Dept of Clinical Rheumatology, Medical University at Lubeck, Lubeck, Germany, 5Hannover Medical School, Hanover, Germany

    Background/Purpose: Takayasu arteritis (TA) may be difficult to diagnose since  diagnostic biomarkers have not been established so far. In a previous study, we could show…
  • Abstract Number: 2381 • 2012 ACR/ARHP Annual Meeting

    Serum Level of IL-33 and Soluble ST2 and Their Association with Disease Activity in Patients with Behcet’s Disease

    Dae-Jun Kim1, Jae-Ho Lee1, Ji Hyeon Ju1, Sung-Hwan Park2, Ho-Youn Kim1 and Seung-Ki Kwok1, 1Division of Rheumatology, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, South Korea, 2Rheumatism Research Center, Catholic Research Institute of Medical Science, The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, South Korea

    Background/Purpose: Interleukin-33 (IL-33) is a new member of the IL-1 family of cytokines which signals via receptor, ST2(IL-33R), and has an important role in Neutrophil…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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