Abstracts Archive - Page 2428 of 2607 - ACR Meeting Abstracts

Abstract Number: 2690 • 2012 ACR/ARHP Annual Meeting
Assessment of Sleep Quality in Patients with Rheumatoid Arthritis
Ulku Ucar and Mehmet Tuncay Duruöz, PMR Department, Rheumatology Division, Celal Bayar University Medical School, Manisa, Turkey
Background/Purpose: Rheumatoid arthritis is a chronic inflammatory disease affecting mainly diartrodial synovial joints. Fatigue and sleep disturbances are commonly seen symptoms in RA patients which…
Abstract Number: 2692 • 2012 ACR/ARHP Annual Meeting
Diet and Other Lifestyle Related Factors and the Risk of Developing Rheumatoid Arthritis
Björn Sundström¹, Ingegerd Johansson² and Solbritt Rantapää Dahlqvist³, ¹Department of Public Health & Clinical Medicine, Rheumatology, Umeå University, Umeå, Sweden, ²Department of Odontology, Cariology, Umeå Universitet, Umeå, Sweden, ³Department of Public Health and Clinical Medicine/Rheumatology, Umeå University Hospital, Umeå, Sweden
Background/Purpose: There is a growing interest in the role of lifestyle in developing chronic diseases, such as rheumatoid arthritis (RA). Our aim was to investigate…
Abstract Number: 2693 • 2012 ACR/ARHP Annual Meeting
Factors Associated with Person-Perceived Disability in Adults Aged 18+ with Rheumatoid Arthritis
Yeliz Greenhill¹, Alison Hammond² and Sarah Tyson¹, ¹Centre for Health Sciences Research, University of Salford, Manchester, United Kingdom, ²Centre for Health Sciences Research, University of Salford, Greater Manchester, United Kingdom
Background/Purpose: Rheumatoid Arthritis (RA) is associated with high risk of disability (1). Loss of independence is negatively correlated with the person’s health and wellbeing (2).…
Abstract Number: 2694 • 2012 ACR/ARHP Annual Meeting
Examination of a Multidimensional Model of Disability and Role Functioning in Patients with Rheumatoid Arthritis
Sarah R. Ormseth¹, Taylor Draper², M. Custodio³, Michael H. Weisman⁴, M.R. Irwin⁵ and Perry M. Nicassio⁵, ¹Cousins Center for PNI, University of California, Los Angeles, Los Angeles, CA, ²Psychology, Loma Linda University, Loma Linda, CA, ³UCLA, Los Angeles, CA, ⁴Cedars-Sinai Medical Center, Los Angeles, CA, ⁵Cousins Center for PNI, UCLA, Los Angeles, CA
Background/Purpose: Disability and impairments in role functioning are common obstacles for many patients with RA. A combination of disease-related and psychosocial factors may contribute to…
Abstract Number: 2670 • 2012 ACR/ARHP Annual Meeting
Genome-Wide Association Study On the Severity of Joint Destruction in Autoantibody Positive Rheumatoid Arthritis Identifies a Role for Sperm Associated Antigen 16
Rachel Knevel¹, Kerstin Klein², Klaartje Somers³, Caroline Ospelt⁴, Jeanine J. Houwing-Duistermaat⁵, Jessica van Nies⁶, Diederik P.C. de Rooy⁶, Laura de Bock⁷, Joris Schonkeren⁸, Gerrie Stoeken-Rijsbergen⁶, Jenna Kiridly⁹, Luis Rodriguez-Rodriguez⁹, Quinta Helmer⁵, Piet Sinissen³, Tom W. J. Huizinga¹, René E.M. Toes¹, Steffen Gay¹⁰, Peter K. Gregersen¹¹, Veerle Somers⁷ and Annette H.M. van der Helm - van Mil⁸, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Center of Experimental Rheumatology, University Hospital Zurich and Zurich Center of Integrative Human Physiology (ZIHP),, Zurich, Switzerland, ³Hasselt University, Biomedical Research Institute, Diepenbeek, Belgium, ⁴Center of Experimental Rheumatology, University Hospital Zurich and Zurich Center of Integrative Human Physiology (ZIHP), Switzerland, Zurich, Switzerland, ⁵Department of Medical Statistics and Bioinformatics, Leiden, Netherlands, ⁶Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁷Hasselt University, Biomedical Research Institute, Belgium, ⁸Leiden University Medical Center, Leiden, Netherlands, ⁹Feinstein Institute for Medical Research and North Shore–Long Island Jewish Health System, Manhasset, New York, ¹⁰Center of Experimental Rheumatology, University Hospital Zurich, Zurich, Switzerland, ¹¹Genomics and Human Genetics, Feinstein Institute for Medical Research, Manhasset, NY
Background/Purpose: Recent genome-wide association studies (GWAs) have identified >30 SNPs predisposing to Rheumatoid Arthritis (RA). These variants are helpful in unraveling the pathogenesis of RA.…
Abstract Number: 2658 • 2012 ACR/ARHP Annual Meeting
Correlation Between Mefv Genotype and Interleukin (IL)1β secretion and Role of the nlr Family Pyrin Domain Containing 3 (Nlrp3) Inflammasome in Patients with Familial Mediterranean Fever (FMF)
Alessia Omenetti¹, Sonia Carta², Delfino Laura², Alberto Martini³, Anna Rubartelli⁴ and Marco Gattorno¹, ¹Pediatrics II Unit G Gaslini Institute, Genoa, Italy, ²Cell Biology, lST-San Martino, Genoa, Italy, ³Pediatric Rheumatology Collaborative Study Group [PRSCG], Cincinnati, OH, ⁴lST-San Martino, Genoa, Italy, Genoa, Italy
Background/Purpose: Familial Mediterranean Fever (FMF) is an autoinflammatory disease due to mutations of MEFV gene which encodes for Pyrin. FMF does not behave as a…
Abstract Number: 2659 • 2012 ACR/ARHP Annual Meeting
An Expanded Repertoire of Anti-Citrullinated Peptide Antibodies Is Associated with Interstitial Lung Disease in Rheumatoid Arthritis
Jon T. Giles¹, Sonye Danoff², Jeremy Sokolove³, Robert Winchester⁴, Dimitrios A. Pappas⁵, Catriona Cramb⁶, Geoffrey Connors⁷, Stanley S. Siegelman⁸, William H. Robinson⁹ and Joan M. Bathon⁵, ¹Medicine, Columbia University, New York, NY, ²Medicine/Pulmonary, Johns Hopkins School of Medicine, Baltimore, MD, ³Medicine, VA Palo Alto Health Care System and Stanford University, Palo Alto, CA, ⁴Dept of Medicine & Pathology, Columbia University, New York, NY, ⁵Columbia University, New York, NY, ⁶VA Palo Alto Heatlh Care System and Stanford University, Palo Alto, CA, ⁷Division of Pulmonary and Critical Care Medicine, Yale University, New Haven, CT, ⁸Department of Radiology, Johns Hopkins University, Baltimore, MD, ⁹Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA
Background/Purpose: Interstitial lung disease (ILD) is an outcome with high morbidity and mortality in rheumatoid arthritis (RA). Citrullinated proteins are observed in these lung tissues;…
Abstract Number: 2660 • 2012 ACR/ARHP Annual Meeting
Progressive Radiographic Joint Damage in Established Rheumatoid Arthritis: Common and Strongly Associated with Seropositivity
Siri Lillegraven¹, Nancy A. Shadick², Zarif Jabbar-Lopez³, Anna Potapov³, Michelle A. Frits⁴, Christine K. Iannaccone⁴, Espen A. Haavardsholm¹, Tore K. Kvien⁵, Michael Weinblatt² and Daniel H. Solomon⁶, ¹Diakonhjemmet Hospital, Oslo, Norway, ²Brigham and Women's Hospital, Boston, MA, ³Harvard School of Public Health, Boston, MA, ⁴Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ⁵Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁶Division of Rheumatology, Brigham and Women's Hospital, Boston, MA
Background/Purpose: During the last decade, rheumatoid arthritis (RA) research has mainly focused on early disease, as it has become apparent that early and aggressive treatment…
Abstract Number: 2661 • 2012 ACR/ARHP Annual Meeting
Disease Activity Score 28-Joint Count: Are Erythrocyte Sedimentation Rate and C-Reactive Protein Versions Comparable?
Roy Fleischmann¹, Désirée van der Heijde², Andrew S. Koenig³, Ronald Pedersen³, Annette Szumski⁴, Lisa Marshall⁵ and Eustratios Bananis⁴, ¹Southwestern Medical Center at Dallas, University of Texas, Dallas, TX, ²Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Specialty Care, Pfizer Inc, Collegeville, PA, ⁴Specialty Care, Pfizer Inc., Collegeville, PA, ⁵Pfizer Inc., Collegeville, PA
Background/Purpose: Frequently DAS28-CRP is utilized instead of DAS28-ESR to assess rheumatoid arthritis (RA) disease activity; however, values for remission and low disease activity (LDA) for…
Abstract Number: 2633 • 2012 ACR/ARHP Annual Meeting
Independence At Home: Real or Perceived
Hazel L. Breland, Health Professions, Division of Occupational Therapy, Medical University of South Carolina, Charleston, SC
Background/Purpose: Rheumatic conditions are more prevalent among women than men and increase with age. Over 4 million African Americans affected are by rheumatic conditions and…
Abstract Number: 2634 • 2012 ACR/ARHP Annual Meeting
Physical Disability, Perceived Dependence and Depression in Older Women with Osteoarthriti
Kisoo Park¹, Monique A. Gignac² and E. M. Badley³, ¹Preventive Medicine and Institute of health science, Gyeongsang National University, Jinju, South Korea, ²Divison of Health Care & Outcomes Research, Arthritis Community Research and Evaluation Unit , Toronto Western Research Institute and University of Toronto, Toronto, ON, Canada, ³Division of Health Care and Outcomes Research,Toronto Western Research Institute; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada
Background/Purpose: Older women with osteoarthritis (OA) often report difficulty with tasks and needing to rely on others for assistance. In addition, depressed mood has been…
Abstract Number: 2635 • 2012 ACR/ARHP Annual Meeting
Exploring the Influence of Patient Perceptions On Medication Escalation in Daily Practice
Jos Hendrikx¹, Wietske Kievit², Jaap Fransen² and Piet L.C.M. van Riel², ¹Rheumatology (470), Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ²Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
Background/Purpose: In rheumatoid arthritis (RA), patients' and physicians' perceptions of disease can differ and patients who are satisfied with their health do not tend to…
Abstract Number: 2636 • 2012 ACR/ARHP Annual Meeting
Understanding Why Treat-to-Target Strategies Are Difficult to Follow
Liana Fraenkel¹, Meaghan Cunningham² and Paul Falzer³, ¹Medicine, Section of Rheumatology, Yale University School of Medicine, Veterans Affairs Connecticut Healthcare System, New Haven, CT, ²Medicine, Yale University School of Medicine, New Haven, CT, ³Medicine, VA Connecticut Healthcare System, New Haven, CT
Background/Purpose: Treat-to-target (T2T) refers to a set of decision strategies widely advocated for the optimal management of rheumatoid arthritis (RA). Despite considerable evidence that this…
Abstract Number: 2637 • 2012 ACR/ARHP Annual Meeting
Cost-Effectiveness and Cost-Utility Analysis of Treat-to-Target Versus Usual Care in Early Rheumatoid Arthritis: Results of the Dutch Rheumatoid Arthritis Monitoring Registry
Marloes Vermeer¹, Wietske Kievit², Ina H. Kuper³, Annemarie Braakman-Jansen⁴, Hein J. Bernelot Moens⁵, Theo R. Zijlstra⁶, Alfons A. den Broeder⁷, Piet L.C.M. van Riel², Jaap Fransen² and Mart A.F.J. van de Laar¹, ¹University of Twente & Medisch Spectrum Twente, Enschede, Netherlands, ²Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ³Medisch Spectrum Twente, Enschede, Netherlands, ⁴Psychology & Communication, University of Twente, Enschede, Netherlands, ⁵Ziekenhuisgroep Twente, Hengelo, Netherlands, ⁶Isala Klinieken, Zwolle, Netherlands, ⁷Rheumatology, Maartenskliniek, Nijmegen, Netherlands
Cost-Effectiveness and Cost-Utility Analysis of Treat-to-Target Versus Usual Care in Early Rheumatoid Arthritis: Results of the Dutch Rheumatoid Arthritis Monitoring RegistryBackground/Purpose: Treat-to-target (T2T) has proven…
Abstract Number: 2638 • 2012 ACR/ARHP Annual Meeting
Biologic Switching Among Patients with Rheumatoid Arthritis in the United States, 2004-2011
Ozgur Tunceli¹, Jeffrey R. Curtis², Tatia C. Woodward³, Siting Zhou¹, Yen-Wen Chen⁴ and Ancilla W. Fernandes³, ¹HealthCore, Inc., Wilmington, DE, ²Rheumatology & Immunology, Univ of Alabama-Birmingham, Birmingham, AL, ³MedImmune, LLC, Gaithersburg, MD, ⁴HealthCore, Inc, Wilmington, DE
Background/Purpose: While studies have assessed the efficacy of switching among biologic disease-modifying antirheumatic drugs (bDMARD), there is a lack of knowledge regarding the patterns of…

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