Abstracts Archive - Page 2402 of 2425 - ACR Meeting Abstracts

Abstract Number: 303 • 2012 ACR/ARHP Annual Meeting
Ancestral Group Differences in Pediatric SLE Early Disease Severity: An Analysis of the Carranet Registry
Jennifer M.P. Woo¹, Alice DC Hoftman¹, Emily von Scheven², Deborah K. McCurdy³, Ornella J. Rullo¹ and CARRA Registry Investigators⁴, ¹Pediatric Rheumatology, Mattel Children's Hospital, University of California, Los Angeles, Los Angeles, CA, ²Pediatric Rheumatology, University of California, San Francisco, San Francisco, CA, ³Pediatric Rheumatology, UCLA Division of Pediatric Rheumatology, Los Angeles, CA, ⁴Durham, NC
Background/Purpose: Ancestral background may contribute to increased disease morbidity in patients with pediatric lupus systemic erythematosus (pSLE) of non-European descent; however, there exists a paucity…
Abstract Number: 304 • 2012 ACR/ARHP Annual Meeting
Burden of Childhood Central Nervous System Vasculitis: Identifying High Risk Factors for Poor Cognitive Outcome
Peter J. Gowdie¹, Marinka Twilt¹, Pascal N. Tyrrell¹, Robyn Westmacott², Tania Cellucci¹, Shehla Sheikh¹, Nick Blancette¹ and Susanne M. Benseler¹, ¹Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ²Psychology, The Hospital for Sick Children, Toronto, ON, Canada
Background/Purpose: Childhood primary angiitis of the CNS (cPACNS) is an increasingly recognized, reversible cause of severe neurological and psychiatric deficit such as stroke, refractory seizures…
Abstract Number: 305 • 2012 ACR/ARHP Annual Meeting
Clinicopathologic Correlates for Activity and Damage of Lupus Nephritis in Childhood-Onset Systemic Lupus Erythematosus
Ravi Nunna¹, Rina Mina¹, Michael Bennett², Shannen Nelson³, Jessica Hummel⁴, Prasad Devarajan², David Witte³ and Hermine Brunner⁵, ¹Rheumatology, Cincinnati Children's Hospital Medical Center/University of Cincinnati, Cincinnati, OH, ²Nephrology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, ³Rheumatology, Cincinnati Children's Hospital, Cincinnati, OH, ⁴Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁵Cincinnati Children's Hospital, Cincinnati, OH
Background/Purpose: High AI activity (AI), tubulointerstitial (TI), and chronicity index (CI) scores from renal biopsy may predict poor renal outcomes in lupus nephritis (LN)…
Abstract Number: 306 • 2012 ACR/ARHP Annual Meeting
Children with Probable SLE by ACR Criteria May Need More Aggressive Lupus Treatment Early in the Disease Course
Anjali Patwardhan¹, Igor Dvorchik² and Charles H. Spencer³, ¹Pediatric Rheumatology, Nationwide Childrens Hospital, Columbus, OH, ²Biostatistics Division, Nationwide Children's Hospital,, Columbus, OH, ³Rheumatology, Nationwide Childrens Hospital, Columbus, OH
Background/Purpose: This research explores whether delay of the childhood-onset SLE (cSLE) diagnosis until 4/11 ACR criteria are met affects patient outcome negatively Methods: Institutional Review…
Abstract Number: 307 • 2012 ACR/ARHP Annual Meeting
Risk Factors for Poor Outcomes in Hospitalized Patients with Pediatric Systemic Lupus Erythematosus
Mary Beth F. Son¹, Victor M. Johnson², Mindy S. Lo³ and Karen H. Costenbader⁴, ¹Division of Rheumatology and Immunology, University Children's Medical Institute, Singapore, Singapore, ²Department of Anesthesiology, Perioperative and Pain Medicine, Children's Hospital Boston, Boston, MA, ³Division of Immunology, Boston Children's Hospital, Boston, MA, ⁴Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Disparities in care among adults with SLE are well documented. We investigated associations of demographic factors and volume of annual inpatient hospital admissions with…
Abstract Number: 308 • 2012 ACR/ARHP Annual Meeting
Next-Generation Sequencing of Urinary Microrna in Human Lupus Nephritis
Beatrice Goilav¹, Iddo Z. Ben-Dov², Irene Blanco³, Olivier Loudig⁴, Dawn M. Wahezi⁵ and Chaim Putterman⁶, ¹Division of Nephrology, Children's Hospital at Montefiore, Bronx, NY, ²Laboratory of RNA Molecular Biology, The Rockefeller University, New York, NY, ³Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ⁴Epidemiology, Albert Einstein College of Medicine, Bronx, NY, ⁵Pediatric Rheumatology, Children's Hospital Montefiore, Bronx, NY, ⁶Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY
Background/Purpose: Lupus nephritis (LN) is a common manifestation of SLE associated with significant morbidity and mortality. microRNAs (miRs) are small non-coding RNAs that regulate translation…
Abstract Number: 268 • 2012 ACR/ARHP Annual Meeting
Knee Osteoarthritis and Serum Uric Acid Concentration: The Third National Health and Examination Survey
Tony Ning¹, Carl Pieper², Virginia B. Kraus³, William E. Kraus⁴ and Kim M. Huffman⁴, ¹Rheumatology, Duke University Medical Center, Durham, NC, ²Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, ³Medicine/Rheumatology, Duke University Medical Center, Durham, NC, ⁴Medicine, Duke University Medical Center, Durham, NC
Background/Purpose: Osteoarthritis (OA) is a disease that is thought to be the result of many factors, which includes inflammatory causes. A recent study examined the…
Abstract Number: 270 • 2012 ACR/ARHP Annual Meeting
Use of Drug Combinations in Patients with Osteoarthritis: A Population-Based Cohort Study
Daniel Prieto-Alhambra¹ and Rosa Morros², ¹Internal Medicine; Primary Care; NDORMS Dept; MRC Lifecourse Epidemiology Unit, URFOA-IMIM, Parc de Salut Mar; Idiap Jordi Gol; University of Oxford; University of Southampton, Barcelona, Spain, ²Primary Care, IDIAP Jordi Gol; Institut Català de la Salut, Spain
TITLE: "Use of drug combinations in patients with osteoarthritis: a population-based cohort study."Background/Purpose: Patients affected with osteoarthritis (OA) use different drugs in search for relief.…
Abstract Number: 271 • 2012 ACR/ARHP Annual Meeting
Bone Marrow Lesions in Knees with Osteoarthritis: Can Parameters From Dynamic Contrast Enhancement Predict Change in Bone Marrow Lesion Volume or Knee Pain Change?
Andrew D. Gait¹, Timothy F. Cootes¹, Elizabeth J. Marjanovic¹, Matthew J. Parkes², Charles E. Hutchinson³ and David T. Felson⁴, ¹Imaging Sciences, School of Cancer & Enabling Sciences, University of Manchester, Manchester, United Kingdom, ²Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom, ³Warwick Medical School, University of Warwick, Coventry, United Kingdom, ⁴ARC Epidemiology Unit, University of Manchester, Manchester, United Kingdom
Background/Purpose: Dynamic contrast enhancement is a powerful tool for highlighting features of a medical image which may not otherwise be seen on "static" scans. While…
Abstract Number: 272 • 2012 ACR/ARHP Annual Meeting
Interim Safety Analysis of a Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy Study of Apremilast (CC10004) in Subjects with Erosive Hand Osteoarthritis
Juergen Rech¹, Wolfgang Ochs², Wolfgang Spieler³, Herbert Kellner⁴, Ulf Müller-Ladner⁵, Mathias Grunke⁶, Matthias Schneider⁷ and Georg Schett⁸, ¹Department of Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen, Germany, ²Rheumatologist in private practice, Bayreuth, Germany, ³Rheumatology Specialty Practice, Zerbst, Germany, ⁴Centre for Inflammatory Joint Diseases, Munich, Germany, ⁵Abt. f. Rheumatologie u. klinische Immunologie, Osteologie, Physikalische Therapie, Kerckhoff-Klinik GmbH, Bad Nauheim, Germany, ⁶Division of Rheumatology, Medizinische Klinik und Poliklinik IV, University of Munich, Munich, Germany, ⁷Department of Endocrinology, Diabetes and Rheumatology, Heinrich-Heine-University, Duesseldorf, Germany, ⁸Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany
Background/Purpose: Apremilast is a small molecule,specific phospodiesterase4 inhibitor under investigation for a number of inflammatory conditions, including psoriasis and psoriatic arthritis. We report results of…
Abstract Number: 273 • 2012 ACR/ARHP Annual Meeting
The Prevalence of Periarticular Lesions On Magnetic Resonance Imaging and Its Relation to Knee Pain in the Community Residents in Korea
In Je Kim¹, Kyeong Min Son², DH Kim³, Yeong Wook Song⁴, Ali Guermazi⁵ and Hyun Ah Kim⁶, ¹Internal Medicine, Hallym University Kangdong Sacred Heart hospital, Seoul, South Korea, ²Division of Rheumatology, Department of Internal Medicine, Hallym university Chunchun sacred heart hospital, Chunchun, South Korea, ³Preventive Medicine, Chunchon, South Korea, ⁴Division of Rheumatology, Department of Internal Medicine, Seoul National University, Seoul, South Korea, ⁵Boston University, Boston, MA, ⁶Department of internal medicine, Hallym University Sacred Heart Hospital, Kyunggi, South Korea
Background/Purpose: The purpose of this study was to investigate the prevalence of periarticular lesions detected by magnetic resonance imaging (MRI) and its association with…
Abstract Number: 274 • 2012 ACR/ARHP Annual Meeting
Childhood Onset Angiitis of the Central Nervous System: What Outcomes Can We Expect?
Lena Das¹, Sook Fun Hoh², Terrence Thomas³ and Thaschawee Arkachaisri⁴, ¹Pediatric Rheumatology, KK Women's and Children's Hospital, Singapore, Singapore, ²Nursing, KK Women's and Children's Hospital, Singapore, Singapore, ³Pediatric Neurology, KK Women's and Children's Hospital, Singapore, Singapore, ⁴Rheumatology & Immunology, KK Women's and Children's Hospital and Duke-NUS Graduate Medical School, Singapore, Singapore
Background/Purpose: Imaging findings in large-medium vessel Childhood Onset Primary and Secondary Angiitis of the Central Nervous System (cPACNS & cSACNS) are well described, however, structural…
Abstract Number: 275 • 2012 ACR/ARHP Annual Meeting
Pediatric Rheumatology Practitioners Experience with Biologics in Juvenile Dermatomyositis: Survey Results
Anjali Patwardhan¹, Kelly A. Rouster-Stevens², Harry L. Gewanter³, Grant D. Syverson⁴, Renee F. Modica⁵, Kara M. Schmidt⁶ and Charles H. Spencer⁷, ¹Pediatric Rheumatology, Nationwide Childrens Hospital, Columbus, OH, ²Pediatric Rheumatologist, Emory-Children's Center, Atlanta,, GA, ³Pediatric & Adolescent HP, Pediatric & Adolescent HP, Midlothian, VA, ⁴Pediatric Rheumatology, Medical College of Wisconsin, Wauwatosa, WI, ⁵Pediatric Rheumatology, University of Florida, Gainesville, FL, ⁶Pediatric Rheumatology, Univ of Louisville, Louisville, KY, ⁷Rheumatology, Nationwide Childrens Hospital, Columbus, OH
Background/Purpose: Biologic therapy is increasingly prescribed in rheumatologic disorders. Juvenile dermatomyositis (JDM), the most common inflammatory myopathy in children, can be challenging to manage in…
Abstract Number: 276 • 2012 ACR/ARHP Annual Meeting
Development of a Longitudinal, Propective Cohort of Young Adults with Childhood-Onset Systemic Lupus Erythematosus
Aimee Hersh¹, Erica F. Lawson², Emily von Scheven³, Edward H. Yelin⁴ and John F. Bohnsack⁵, ¹Pediatrics, University of Utah, Salt Lake City, UT, ²Pediatric Rheumatology, UC San Francisco, San Francisco, CA, ³Pediatric Rheumatology, University of California, San Francisco, San Francisco, CA, ⁴Medicine, UC San Francisco, San Francisco, CA, ⁵Dept of Pediatriacs, University of Utah, Salt Lake City, UT
Background/Purpose: Data on the adult outcomes of childhood-onset systemic lupus erythematosus (cSLE ) are lacking, and a feasible methodology is needed to obtain long-term follow-up…
Abstract Number: 277 • 2012 ACR/ARHP Annual Meeting
Dyslipidemia in Juvenile Dermatomyositis: The Role of Disease Activity
Katia T. Kozu¹, Clovis Artur Silva², Eloisa Bonfa³, Adriana M. Sallum⁴, Rosa M.R. Pereira⁵, Vilma S. Viana⁶, Eduardo F. Borba⁷ and Lucia M. A. Campos⁴, ¹Pediatric Rheumatology Unit, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²Paediatric Rheumatology International Trials Organization (PRINTO), Istituto Giannina Gaslini, Genova, Italy, ³Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁴Pediatric Rheumatology Unit, Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, ⁵Rheumatology, University of São Paulo, São Paulo, Brazil, ⁶Rheumatology Division, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, ⁷Rheumatology Division, University of Sao Paulo, Sao Paulo, Brazil
Background/Purpose: Dyslipidemia has been infrequently investigated in pediatric population with autoimmune rheumatic diseases. However, lipid abnormalities in these diseases may occur due to multiple risk…

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