Abstracts Archive - Page 2395 of 2605 - ACR Meeting Abstracts

Abstract Number: 501 • 2013 ACR/ARHP Annual Meeting
A Randomized Placebo-Controlled Phase 2 Study To Evaluate Efficacy, Safety and Tolerability Of Two Secukinumab Loading Dose Regimens In Subjects With Active Rheumatoid Arthritis Despite Treatment With Methotrexate
Silvano Adami¹, André Beaulieu², Proton Rahman³, Bruno Seriolo⁴, Janet S. Lee⁵, Gerhard Krammer⁶, Brian Porter⁵, Anuradha Thulasiraman⁶ and Hanno B. Richards⁷, ¹Rheumatology Department, University of Verona, Verona, Italy, ²Faculty of Medicine, Laval University, Quebec, QC, Canada, ³Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, ⁴Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genoa, Italy, ⁵Novartis Pharma AG, East Hanover, NJ, ⁶Novartis Pharma AG, Basel, Switzerland, ⁷Clinical Immunology / Dermatology, Novartis Pharma AG, Basel, Switzerland
A Randomized Placebo-Controlled Phase 2 Study to Evaluate Efficacy, Safety and Tolerability of Two Secukinumab Loading Dose Regimens in Subjects with Active Rheumatoid Arthritis Despite…
Abstract Number: 502 • 2013 ACR/ARHP Annual Meeting
Early Introduction Of Biologic Treatment Is An Important Predictor Of Sustained Favorable Outcome Including Clinical Remission In Early Arthritis But Not Of Sustained Favorable Outcome On Structure and Function Only: Results From The Espoir Cohort
Cécile Gaujoux-Viala¹, Laure Gossec², Maxime Dougados³, Francis Guillemin⁴ and Bruno Fautrel⁵, ¹EA 2415, Montpellier I University, Nîmes University Hospital, Rheumatology Department, Nîmes, France, ²Rheumatology, Paris 6 – Pierre et Marie Curie University; AP-HP, Rheumatology, Pitié-Salpêtrière Hospital, - GRC-UPMC 08 – EEMOIS, Paris, France, ³Rheumatology B Department, Paris-Descartes University, APHP, Cochin Hospital, Paris, France, ⁴CHU Nancy, Clinical Epidemiology and Evaluation, Université de Lorraine, Paris Descartes University, APEMAC, EA 4360, Nancy, France, ⁵Paris 6 – Pierre et Marie Curie University; AP-HP, Rheumatology, Pitié-Salpêtrière Hospital, - GRC-UPMC 08 – EEMOIS, Paris, France
Background/Purpose: The relevant elements to evaluate health states in RA should include remission, good functional ability and structural stability [1]. The concept of favorable outcome…
Abstract Number: 503 • 2013 ACR/ARHP Annual Meeting
Sjögren’s Syndrome In American Ethnic and Racial Minorities
Ann Igoe¹, Christopher J. Lessard^2,3, Juan-Manuel Anaya⁴, Astrid Rasmussen², Kiely Grundahl⁵, Biji T. Kurien^6,7,8, Jacen S Maier-Moore⁹, Lida Radfar¹⁰, John A. Ice², Glen D. Houston¹¹, David M. Lewis¹², Donald U. Stone¹³, Kimberly S. Hefner¹⁴, Kathy L. Sivils^2,3 and R. Hal Scofield^6,8,15, ¹Arthritis & Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ³Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁴Center for Autoimmune Diseases Research (CREA), Universidad del Rosario., Bogota, Colombia, ⁵Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, oklahoma CIty, OK, ⁶Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁷U.S. Department of Veterans Affairs Medical Center, Oklahoma City, OK, ⁸College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁹Medicine; Arthritis & Clinical Immunology, University of Oklahoma Health Sciences Center, Oklahoma Medical Research Foundation, Department of Veterans Affairs, Oklahoma City, OK 73104, Oklahoma City, OK, ¹⁰College of Dentristry, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ¹¹Collage of Denistry, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ¹²College of Dentistry, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ¹³Department of Ophthalmology, Dean McGee Eye Institute, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ¹⁴Hefner Eye Care and Optical Center, Oklahoma City, OK, ¹⁵US Department of Veterans Affairs Medical Center, Oklahoma City, OK
Background/Purpose: Examine the racial and ethnic make-up of a large cohort of Sjögren’s syndrome (SS) gathered in the USA compared to the make-up found among…
Abstract Number: 504 • 2013 ACR/ARHP Annual Meeting
Raynaud’s Phenomenon and African American Race Are Independently Associated With Non-Hodgkin’s Lymphoma In Sjogrens Syndrome Patients: Findings From a United States National Study
Bella Mehta¹, Neville Jadeja², Marjan Mujib³ and Petros V. Efthimiou⁴, ¹Internal Medicine, Westchester Medical Center at New York Medical College, valhalla, NY, ²Internal Medicine, Jacobi Medical Center, New York, NY, ³Internal Medicine, New York Medical College, Valhalla, NY, ⁴Medicine/Rheumatology, LM&MHC/Weill Cornell MC, New York, NY
Background/Purpose: , Higher incidence of lymphoma in sjogrens syndrome has been reported since more than 5 decades now. Non Hodgkin's Lymphoma (NHL) ranks as the…
Abstract Number: 505 • 2013 ACR/ARHP Annual Meeting
Damage Accrual In a Single Centre Cohort Of Patients With Primary Sjögren’s Syndrome Followed Up For Over 10 Years
Chiara Baldini¹, Francesco Ferro¹, Pasquale Pepe², Nicoletta Luciano¹, Francesca Sernissi¹, Carlotta Cacciatore¹, Daniela Martini¹, Antonio Tavoni³, Marta Mosca⁴ and Stefano Bombardieri¹, ¹University of Pisa, Rheumatology Unit, Pisa, Italy, ²Institute of Clinical Physiology, National Research Council, Pisa, Italy, ³University of Pisa, Immunoallergology Unit, Pisa, Italy, ⁴Rheumatology Unit, University of Pisa, Pisa, Italy
Background/Purpose: 1) To describe the progression and cumulative prevalence of damage accrued over the time in a single center cohort of patients with primary Sjögren’s…
Abstract Number: 506 • 2013 ACR/ARHP Annual Meeting
Hospitalization In Patients With Primary Sjögren’s Syndrome
Yemil Atisha-Fregoso¹, Yahaira Rivera² and Gabriela Hernandez-Molina², ¹Internal Medicine, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ²Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubirán, Mexico City, Mexico
Background/Purpose: There is scant information on the frequency, main causes and associated risk factors of hospitalization in patients with primary Sjögren syndrome (PSS).We aimed to…
Abstract Number: 507 • 2013 ACR/ARHP Annual Meeting
Level Of Agreement Of The AECG 2002 and ACR 2012 Classification Criteria For Sjögren’s Syndrome In The Brittany Cohort: Clues To Understand Discrepancies
Divi Cornec¹, Alain Saraux², Jacques-Olivier Pers³, Sandrine Jousse-Joulin⁴, Yves Renaudineau³, Beatrice Cochener⁵, Thierry Marhadour⁶ and Valerie Devauchelle-Pensec⁷, ¹Department of rheumatology, Brest Occidentale University, Brest, France, ²Department of rheumatology and unit of immunology (EA 2216), CHU Brest et Université Bretagne Occidentale, Brest, France, ³Unit of immunology, EA 2216, Brest Occidentale University, Brest, France, ⁴Rheumatology, Brest university medical school, EA 2216, UBO and CHU de la Cavale Blanche,, Brest, France, ⁵Department of ophtalmology, Brest Occidentale University, Brest, France, ⁶Rheumatology, CHU de la Cavale Blanche, Brest, France, ⁷Department of rheumatology and unit of immunology (EA2216), Brest Occidentale university, Brest, France
Background/Purpose: New classification criteria for primary Sjögren’s syndrome (pSS) have been proposed in 2012 and approved by the ACR. They differ substantially from the currently…
Abstract Number: 508 • 2013 ACR/ARHP Annual Meeting
Is Ultrasonography Of Salivary Gland a Validate Tool In Sjögren Syndrome? Study 1: Interobserver Reliability Between International Group Of Experts
Sandrine Jousse-Joulin¹, Vera Milic², Elke Theander³, Malin V. Jonsson⁴, Wan-Fai Ng⁵, Chiara Baldini⁶, Marina Carotti⁷, Alan N. Baer⁸, Joel Fradin⁹, Pascale Rachele¹⁰, Hendrika Bootsma¹¹, Jacqueline Brown¹², Nicoletta Luciano⁶, S Bombardieri¹³, Roland Jonsson¹⁴, Salvatore De Vita¹⁵, Alojzija Hocevar¹⁶, Matija Tomsic^17,18, Alain Saraux¹⁹, Emmanuel Nowak²⁰, Alessandro Ciapetti Sr.²¹, Arjan Vissink²², John Rout²³, Thomas Mandl²⁴, Simon J. Bowman²⁵ and Valerie Devauchelle-Pensec²⁶, ¹Rheumatology, Brest university medical school, EA 2216, UBO and CHU de la Cavale Blanche,, Brest, France, ²rheumatology, belgrade university, belgrade, Serbia, ³Section of Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, ⁴Department of Clinical Dentistry - Section for Oral and Maxillofacial Radiology, University of Bergen, Bergen, Norway, ⁵Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom, ⁶University of Pisa, Rheumatology Unit, Pisa, Italy, ⁷Rheumatology and radiology, Ospedali Riuniti, Ancona, Italy, ⁸Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁹Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, ¹⁰radiology, university of Pisa, Pisa, Italy, ¹¹Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, Groningen, Netherlands, ¹²dental division, Tower Wing Guy's hospital, london, United Kingdom, ¹³Department of Clinical and Experimental Medicine, Department of Rheumatology, University of Pisa, Pisa, Pisa, Italy, ¹⁴Broegelmann Research Laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway, ¹⁵Rheumatology, DSMB, University Hospital Santa Maria della Misericordia, Udine, Italy, ¹⁶Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia, ¹⁷Department of Rheumatology, BioRx.si, University Medical Centre Ljubjana, Ljubljana, Slovenia, ¹⁸Faculty of Medicine, Unversity Ljubljana, Ljubljana, Slovenia, ¹⁹Department of rheumatology and unit of immunology (EA 2216), CHU Brest et Université Bretagne Occidentale, Brest, France, ²⁰CIC, CHU Brest, Brest, France, ²¹Department of Rheumatology, Politechnic University of the Marche, Ancona, Ancona, Italy, ²²Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, ²³Birmingham Dental Hospital, Birmingham, United Kingdom, ²⁴Dept of Rheumatology, Skåne University Hospital Malmo, Lund University, Sweden, Malmö, Sweden, ²⁵Department of Rheumatology, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom, ²⁶Department of rheumatology and unit of immunology (EA2216), Brest Occidentale university, Brest, France
Background/Purpose: Ultrasonography (US) of salivary glands is a relatively new test to diagnose primary Sjögren syndrome (pSS)1-6. In 2012, an international group of interest was…
Abstract Number: 509 • 2013 ACR/ARHP Annual Meeting
A Novel Screening Tool Indicative Of Primary Sjogren’s Syndrome Versus Sicca Symptoms
Gerard Dumancas¹, Michael Brown², Indra Adrianto¹, Christopher J. Lessard¹, Jennifer A. Kelly¹, Kiely Grundahl³, Astrid Rasmussen¹, R. Hal Scofield⁴, Courtney Montgomery⁵ and Kathy L. Sivils^1,6, ¹Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ³Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, oklahoma CIty, OK, ⁴US Department of Veterans Affairs Medical Center, Oklahoma City, OK, ⁵Arthritis & Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁶Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK
Background/Purpose: Sjogren's syndrome (SS) is a chronic, progressive disease characterized by dry eyes and dry mouth resulting from lymphocytic infiltration of the lacrimal and salivary…
Abstract Number: 510 • 2013 ACR/ARHP Annual Meeting
Multicentric Analysis Of Inter and Intra Observer Reliabilities For Histopathological Abnormalities In Salivary Gland Biopsy In Primary Sjögren Syndrome
Sebastian Costa¹, Isabelle Quintin Roue², Agnes Lesourd², Sandrine Jousse-Joulin³, Pascale Marcorelles⁴, Eric Hachulla⁵, Vincent Goeb⁶, Marie-Christine Copin⁷, Jean-Marie Berthelot⁸, Jacques-Olivier Pers⁹, Olivier Vittecoq¹⁰, Emmanuel Nowak¹¹, Alain Saraux¹² and Valerie Devauchelle-Pensec¹³, ¹anatomopathological department, Brest university hospital, Brest, France, ²anatomopathological department, Morvan hospital, Brest, France, ³Rheumatology, Brest university medical school, EA 2216, UBO and CHU de la Cavale Blanche,, Brest, France, ⁴anatomopathological department, Brest university hospital, CHU Morvan, Brest, France, ⁵Internal Medicine, Lille CEDEX, France, ⁶Rheumatology, Amiens University Hospital, Amiens, France, ⁷anatomopathological department, Lille university, Lille, France, ⁸Rheumatology Unit, Nantes University Hospital, Nantes, France, ⁹Unit of immunology, EA 2216, Brest Occidentale University, Brest, France, ¹⁰Rheumatology, Rouen University Hospital & Inserm905, University of Rouen, Rouen Cedex, France, ¹¹CIC, CHU Brest, Brest, France, ¹²Department of rheumatology and unit of immunology (EA 2216), Université Brest Occidentale, Brest, France, ¹³Department of rheumatology and unit of immunology (EA2216), Brest Occidentale university, Brest, France
Background/Purpose: : Histopathologic evaluation of minor labial salivary gland (MLSG) is a major goal for the classification of patients with a primary Sjögren syndrome (pSS)…
Abstract Number: 511 • 2013 ACR/ARHP Annual Meeting
Salivary Gland Lymphocyte Pattern Associated With Response To Belimumab In Primary sjogren’ssyndrome: Results Of The Beliss Study
Raphaèle Seror¹, Thierry Lazure², Frederic Desmoulins³, Stephan Pavy⁴, Corinne Miceli-Richard⁵, Gabriel Baron⁶, Philippe Ravaud⁷ and Xavier Mariette⁸, ¹Rheumatology, Université Paris Sud, Le Kremlin Bicêtre, France, ²Pathology, INSERM U1012 - Université Paris XI, Le Kremlin Bicêtre, France, ³Rheumatology, Université Paris-Sud, Le Kremlin Bicêtre, Le Kremlin Bicetre, France, ⁴Rheumatology, Hopital Bicetre, Paris, France, ⁵Rheumatology Department, Université Paris-Sud 11, Bicêtre Hospital,, Kremlin Bicêtre, France, ⁶Hotel Dieu University Hospital Paris, Epidemiology, Paris, France, ⁷Epidemiology, Hopital Hotel Dieu, Paris Descartes University, Paris, France, ⁸Rheumatology Service, Bicêtre University Hospital, Le Kremlin Bicetre, France
Background/Purpose: To address the change in labial salivary gland (LSG) inflammation after Belimumab (biological treatment inhibiting soluble BAFF/BLyS) therapy in pSS patients and identify predictor…
Abstract Number: 512 • 2013 ACR/ARHP Annual Meeting
The Significance Of Ectopic Germinal Center In Minor Salivary Gland Of Patients With Sjögren’s Syndrome
Kyung-Eun Lee¹, Dong-Jin Park¹, Jeong-Won Lee², Ji-Hyoun Kang², Lihui Wen¹, Tae-Jong Kim³, Yong-Wook Park¹ and Shin-Seok Lee⁴, ¹Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, ²Chonnam National University Medical School, Gwangju, South Korea, ³Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, South Korea, ⁴Dept of Int Med/Rheumatology, Chonnam National University Medical School, Gwangju, South Korea
Background/Purpose: To investigate whether the presence of germinal center (GC) in minor salivary glands of patients with Sjögren’s syndrome (SS) is associated with different clinical…
Abstract Number: 513 • 2013 ACR/ARHP Annual Meeting
Diagnostic Value Of Labial Minor Salivary Gland Biopsy For Primary Sjögren’s Syndrome
Raquel Altoe¹, Valeria Valim², Maria Carmem S. Santos³, Erica V. Serrano¹ and Samira T. Miyamoto⁴, ¹Reumatologia, Universidade Federal do Espírito Santo, Vitória, Brazil, ²Clínica Médica - Reumatologia, Universidade Federal do Espírito Santo, Vitória, Brazil, ³Farmacologia, Universidade de Vila Velha, Vitória, Brazil, ⁴Educação Integrada em Saúde - Reumatologia, Universidade Federal do Espírito Santo, Vitoria, Brazil
Background/Purpose: The presence of lymphocytic infiltrate with ≥ 1 focus score/4mm2 in minor salivary gland is a useful tool for the diagnosis of Sjögren's syndrome…
Abstract Number: 514 • 2013 ACR/ARHP Annual Meeting
EULAR Sjögren’s Syndrome Patient Reported Index (ESSPRI) Is Increased In Sjögren’s Syndrome Patient With Fibromyalgia
Valeria Valim¹, Samira T. Miyamoto², Mauricio Paganotti³, Erica V. Serrano⁴ and Raquel Altoe⁴, ¹Clínica Médica - Reumatologia, Universidade Federal do Espírito Santo, Vitória, Brazil, ²Educação Integrada em Saúde - Reumatologia, Universidade Federal do Espírito Santo, Vitoria, Brazil, ³Farmacologia, Universidade de Vila Velha, Vitória, Brazil, ⁴Reumatologia, Universidade Federal do Espírito Santo, Vitória, Brazil
Background/Purpose: The EULAR Sjögren’s Syndrome Patient Reported Index(ESSPRI) is a patient-reported index designed to assess the severity of patients’ symptoms such as dryness, pain and…
Abstract Number: 515 • 2013 ACR/ARHP Annual Meeting
Does Multiplex Flow Immunoassay Underdetect SSA and SSB Antibodies? An Evaluation Of The Sjogren’s International Collaborative Clinical Alliance (SICCA) Cohort
Alan N. Baer¹, Laura Gutierrez², Mara McAdams DeMarco³, Mi Y. Lam⁴, Livia Casciola-Rosen⁵, Stephen Shiboski⁶, Caroline Shiboski⁴ and Lindsey A. Criswell⁷, ¹Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ²Center Tower Ste 5300, Johns Hopkins University, Baltimore, MD, ³Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, ⁴Orofacial Sciences, University of California San Francisco, San Francisco, CA, ⁵Division of Rheumatology, Johns Hopkins University, Baltimore, MD, ⁶University of California, San Francisco, San Francisco, CA, ⁷Department of Medicine, University of California, San Francisco, Rosalind Russell Medical Research Center for Arthritis, San Francisco, CA
Background/Purpose: Multiplex flow immunoassays (MFIA) are used by clinical laboratories to test for antibodies to extractable nuclear antigens. The use of blended Ro52 and…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].