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  • Abstract Number: 0429 • ACR Convergence 2024

    Exploring the Impact of Autoimmune Rheumatic Diseases on Human Milk Macronutrient Composition

    Rashmi Dhital1, Kerri Bertrand2, Essi Heinonen3 and Christina Chambers4, 1UC San Diego, Brentwood, TN, 2UC San Diego, San Diego, CA, 3UC San Diego, La Jolla, CA; Karolinska Institutet, Stockholm, Sweden, San Diego, CA, 4University of California, San Diego, La Jolla, CA

    Background/Purpose: Systemic inflammation in autoimmune rheumatic diseases (ARDs) may alter human milk composition, akin to changes observed in other inflammatory states, indirectly impacting infant health,…
  • Abstract Number: 0389 • ACR Convergence 2024

    Histopathological Features of Liver Tissue Biopsies in SJIA Patients with and Without Clinical Macrophage Activation Syndrome

    Esraa Eloseily1, Lara Berklite2, Jennifer Picarsic1, grant schulert1, Rachel Sheridan1 and Alexei Grom1, 1Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Cincinnati Children's Hospital Medical Center, Cincinnti, OH

    Background/Purpose: Systemic Juvenile Idiopathic Arthritis (SJIA) can present with or without Macrophage Activation Syndrome (MAS), a severe, potentially life-threatening complication. Liver tissue injury is commonly…
  • Abstract Number: 0423 • ACR Convergence 2024

    Higher Risk of Preterm Delivery in Women with Rheumatoid Arthritis: A Matched Comparative Analysis of the GR2 Prospective Cohort and the French National Perinatal Surveys

    Sabrina Hamroun1, Grégoire Martin De Frémont2, Nathalie Costedoat-chalumeau3, Marion couderc4, René-Marc Flipo5, Laure Gossec6, Christophe Richez7, Rakiba Belkhir8, Aline Frazier9, Valerie Devauchelle10, Hubert Marotte11, Jérémie Sellam12, Elisabeth Gervais13, Alban Deroux14, Cedric Lukas15, Emmanuelle Dernis16, Emmanuel Chatelus17, Véronique Le Guern18, Gaëlle Guettrot-Imbert19, Nathalie Lelong20, Camille Le Ray20, Raphaele Seror21 and Anna Molto22, and ENP 2021 and GR2 Study Groups, 1Cochin University Hospital, Paris, Ile-de-France, France, 2Le Kremlin-Bicêtre University Hospital, Le Kremlin-Bicêtre, Guyana, 3University Paris Cité, Paris, France, 4CHU de Clermont-Ferrand, Clermont-Ferrand, 5CHU Lille, Lille, Nord-Pas-de-Calais, France, 6Sorbonne Université, Paris, France, 7Pellegrin Hospital, Rheumatology, Referral Center for Rare Systemic Autoimmune and Autoinflammatory Diseases, Bordeaux, France, 8Service de Rhumatologie, Hôpital Bicêtre, AP-HP, Le Kremlin-Bicêtre, France, 9Lariboisière University Hospital, Paris, France, 10UBO, Brest, France, 11Université Jean Monnet, CHU Saint-Etienne, Mines Saint-Etienne, INSERM SAINBIOSE 1059, Saint-Etienne, France, 12Saint-Antoine Hospital - AP-HP, Paris, Ile-de-France, France, 13University hospital, Poitiers, France, 14Clinique Universitaire de Médecine Interne, Department of Internal Medicine, Grenoble University Hospital, Grenoble, France, 15Rheumatology department, CHU Montpellier, Montpellier, France, 16CH LE MANS, LE MANS, Pays de la Loire, France, 17Rheumatology department strasbourg, Strasbourg, France, 18APHP, Hôpital Cochin, Paris, 19Cochin Hospital, Paris, France, 20University of Paris, INSERM Obstetrical, Perinatal and Pediatric Epidemiology Research Team, Paris, France, 21Service de Rhumatologie, Hôpital Bicêtre, AP-HP, le Kremlin Bicetre, Ile-de-France, France, 22Groupe Hospitalier Cochin, AP-HP, Paris, France

    Background/Purpose: Rheumatoid arthritis (RA) regularly affects women of childbearing age1. A higher obstetric morbidity in women with RA is suggested in the literature in several…
  • Abstract Number: 0394 • ACR Convergence 2024

    Unveiling Major Challenges and Unmet Needs in the Therapeutic Approach to Systemic Juvenile Idiopathic Arthritis: The Patient Perspective

    Francesco Baldo1, Luciana Peixoto2, Remco Erkens3, Greta Rogani3, Claudia Bracaglia4, Dirk Foell5, Marco Gattorno6, Marija Jelusic7, Sebastiaan Vastert3, Rashmi Sinha2 and Francesca Minoia8, and on behalf of the PReS MAS/sJIA Working Party and the Systemic JIA Foundation, 1Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy, 2Systemic JIA Foundation, Cincinnati, OH, 3University Medical Center Utrecht, Utrecht, Netherlands, 4IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy, 5University Hospital Muenster, Muenster, Germany, 6IRCCS Giannina Gaslini, Genoa, Italy, 7University of Zagreb School of Medicine, University Hospital Centre Zagreb, Zagreb, Zagreb, Croatia, 8Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Milan, Italy

    Background/Purpose: Despite continuous improvements in the therapeutic options for children with systemic juvenile idiopathic arthritis (sJIA), access to medications significantly differs among centres and countries.…
  • Abstract Number: 0464 • ACR Convergence 2024

    Increases in Paraoxonase-1 Activity over Time Associates with Reduced Risk of Incident Inflammatory Arthritis in an Anti-Citrullinated Protein Antibody-Positive Population

    Amir Razmjou1, Rong Guo2, David Elashoff3, Kevin Deane4, Jill Norris5, Marie Feser6, Jennifer Wang1, Ani Shahbazian2 and christina Charles-Schoeman7, 1UCLA, Los Angeles, CA, 2UCLA, Los Angeles, 3UCLA Department of Medicine Statistics Core, Los Angeles, 4University of Colorado Denver Anschutz Medical Campus, Aurora, CO, 5Colorado School of Public Health, Denver, CO, 6Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, 7UCLA Medical Center, Santa Monica, CA

    Background/Purpose: Rheumatoid arthritis (RA) has a well described pre-clinical state, with a continuum of genetic and environmental risk factors leading to the development of systemic…
  • Abstract Number: 0469 • ACR Convergence 2024

    SCORE2 Is Superior to SCORE in Predicting the Presence of Carotid Plaques and Intima-media Thickness in Rheumatoid Arthritis Patients: A Cross-sectional Study with Carotid Ultrasound

    Cristina Campos Fernández1, Jorge Juan Fragío Gil2, Roxana González Mazario3, Pablo Martínez Calabuig4, Laura Salvador Maicas5, Mireia Lucía Sanmartín Martínez6, Iván Jesús Lorente Betanzos6, Clara Molina Almela6, juan José Lerma Garrido7, Amalia Rueda3 and Jose A Román-Ivorra8, 1Escuela de Doctorado, Universidad Católica de Valencia San Vicente Mártir, Valencia, Spain, 2Hospital General Universitario, Valencia, Comunidad Valenciana, Spain, 3Hospital General de Valencia, Valencia, Comunidad Valenciana, Spain, 4HOSPITAL GENERAL UNIVERSITARIO VALENCIA SPAIN, Ontinyent, Comunidad Valenciana, Spain, 5Consorcio Hospital General Universitario de Valencia, Castellón de la Plana, Comunidad Valenciana, Spain, 6Consorcio Hospital General Universitario de Valencia, Valencia, Comunidad Valenciana, Spain, 7Hospital General Universitario Valencia, Valencia, Comunidad Valenciana, Spain, 8Hospital Universitari i Politècnic la Fe, Valencia, Comunidad Valenciana, Spain

    Background/Purpose: Rheumatoid arthritis (RA) escalates the risk of premature mortality, predominantly through cardiovascular diseases. Although SCORE and its updated version, SCORE2, are employed to assess…
  • Abstract Number: 0468 • ACR Convergence 2024

    Plasma Calprotectin Assessed in Multiple Biological Treatment Strategies for Early Rheumatoid Arthritis over 48 Weeks

    David Stevens1, Lene Sundbakk2, Amirhossein Kazemi2, Marte Heiberg3, Tuulikki Sokka-Isler4, Bjorn Gudbjornsson5, Kristina Lend6, Anna Rudin7, Michael Nurmohamed8, Jon Lampa9, Merete Hetland10, Mikkel Ostergaard11, Ronald Van Vollenhoven12, Tillmann Uhlig2, Espen Haavardsholm2 and Hilde Hammer3, 1St. Olavs hospital, Trondheim, Norway, 2Diakonhjemmet Hospital, Oslo, Norway, 3Diakonhjemmet Hospital, Oslo, Oslo, Norway, 4University of Eastern Finland, Faculty of Health Sciences, Jyvaskyla, Finland, 5Landspitali University Hospital and University of Iceland, Reykjavik, Iceland, 6Amsterdam UMC, Karolinska Institute, Stockholm, Sweden, 7Institute of Medicine, University of Gothenburg, Gothenburg, Sweden, 8Amsterdam University Medical Centers, Amsterdam, Netherlands, 9Karolinska University Hospital, Hässelby, Sweden, 10Rigshospitalet Glostrup and University of Copenhagen, Glostrup, Denmark, 11Department of Clinical Medicine, University of Copenhagen and Center for Rheumatology, Copenhagen Center for Arthritis Research, Glostrup, Denmark, 12Department of Rheumatology and Clinical Immunology, Amsterdam University Medical Centers, Amsterdam, Netherlands

    Background/Purpose: Plasma calprotectin is a sensitive biomarker of inflammation in patients with rheumatoid arthritis (RA) and reflects activation of granulocytes and macrophages. Calprotectin has not…
  • Abstract Number: 2495 • ACR Convergence 2024

    Diffuse Alveolar Hemorrhage in Patient with ANCA-associated Vasculitis AndInterstitial Lung Disease

    Elif Ediboglu1, Samuel Falde1, Misbah Baqir1, Rodrigo Cartin-Ceba2 and Ulrich Specks1, 1Mayo Clinic, Rochester, MN, 2Mayo Clinic, Scottsdale, AZ

    Background/Purpose: The association of interstitial lung disease (ILD) and microscopic polyangiitis (MPA) is increasingly recognized. The implications of ILD as it relates to clinical outcomes…
  • Abstract Number: 0388 • ACR Convergence 2024

    The Association Between Body Composition and Disease and Treatment Outcomes in Patients with Juvenile Idiopathic Arthritis: Results from the CAPRI Registry

    Samantha Morin1, KAREN BEATTIE2, Roxana Bolaria3, Tania Cellucci4, Gaelle Chedeville5, Amieleena Chhabra6, Paul Dancey7, Tommy Gerschman8, Liane Heale9, Julie Herrington2, Adam Huber10, Mehul Jariwala11, Jean-Philippe Proulx-Gauthier12, Dax Rumsey13, Heinrike Schmeling14, Jaime Guzman15 and Michelle Batthish4, and CAPRI Registry Investigators, 1McMaster University, Hamilton, Canada, 2McMaster University, Hamilton, ON, Canada, 3Victoria Arthritis Center, Victoria, BC, Canada, 4McMaster Children's Hospital, Hamilton, ON, Canada, 5The Montreal Children's Hospital, Montreal, QC, Canada, 6University of British Columbia, Penticton, BC, Canada, 7Memorial University, St. John's, Canada, 8University of British Columbia - Vancouver, North Vancouver, BC, Canada, 9McMaster University, Oakville, ON, Canada, 10IWK Health Centre, Halifax, NS, Canada, 11Jim Pattison Children's Hospital, Saskatoon, Canada, 12CHU de Quebec - Universite Laval, Quebec, QC, Canada, 13University of Alberta, Edmonton, AB, Canada, 14University of Calgary, Calgary, AB, Canada, 15University of British Columbia and BC Children's Hospital, Vancouver, BC, Canada

    Background/Purpose: Recent evidence has linked abnormal body weight, underweight or obesity, with poor disease outcomes in adults with inflammatory arthritis. Yet, little is known about…
  • Abstract Number: 0391 • ACR Convergence 2024

    Using Machine Learning to Predict Inactive Disease in Juvenile Idiopathic Arthritis

    Mei-Sing Ong1, Marc Natter2, Laura Schanberg3 and Yukiko Kimura4, and CARRA Registry Investigators, 1Harvard Medical School & Harvard Pilgrim Healthcare Institute, Boston, MA, 2Boston Children's Hospital, Boston, MA, 3Duke University Medical Center, DURHAM, NC, 4Hackensack Meridian School of Medicine, New York, NY

    Background/Purpose: Optimizing treatment of JIA continues to be a challenge. Biologic DMARD (bDMARD) therapies have significantly improved outcomes but is costly, may be more difficult…
  • Abstract Number: 2517 • ACR Convergence 2024

    Skin Microbiome Shows Differences Between Pathergy Positive and Negative Patients with Behçet’s Syndrome

    Betul Sarac1, Ayse Kalkanci2, Esra Kilic2, Elif Ayca Sahin2, Yesim Ozguler3 and Gulen Hatemi3, 1Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Istanbul, Turkey, 2Gazi University, Faculty of Medicine, Department of Medical Microbiology, Ankara, Turkey, 3Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey

    Background/Purpose: Gut, oral and genital mucosa microbiome studies in Behçet’s syndrome have shown heterogeneous results including reduced bacterial diversity and decrease in butyrate-producing bacteria. A…
  • Abstract Number: 0474 • ACR Convergence 2024

    Association Between Rheumatoid Arthritis and Survival After Cancer: A Systematic Literature Review and Meta-analysis

    Joshua Hsieh1, Avneet Kaur2, Hemant Khandelia3, Teresa Jewell4, Aman Singh5, Lauren Barkley6, Ishan Bansal7, Simmi Oberoi8 and Namrata Singh9, 1Lakeside High School, Seattle, WA, 2SUNY Upstate, Buffalo, NY, 3AIIMS, New Delhi, Delhi, India, 4University of Washington, Seattle, WA, 5Rajindra Hospital, Patiala, Punjab, India, 6Brandeis University, Boston, MA, 7Yale University, New Haven, CT, 8Rajindra Hospital, New Delhi, India, 9University of Washington, Bellevue, WA

    Background/Purpose: Increasing evidence suggests that inflammation, a hallmark of rheumatoid arthritis (RA), is associated with an elevated risk of cancer and can influence cancer outcomes.…
  • Abstract Number: 0445 • ACR Convergence 2024

    Evaluating Clinical Reasoning in Randomized Surveys of Lupus Nephritis and Preeclampsia Pregnancy Case Workups: A Clinical Conundrum

    Liya Stolyar1, Sadaf Sediqi2, Richard Lafayette3, Maurice Druzin4, Saadiya Hawa5, Amanda Moyer6, Yashaar Chaichian2 and Julia Simard2, 1Palo Alto VA Medical Center/Stanford, Stanford, CA, 2Stanford School of Medicine, Stanford, CA, 3Stanford, Stanford, CA, 4Stanford University School of Medicine, Stanford, CA, 5Weiss Memorial Hospital, Chicago, IL, 6Stanford University, San Bruno, CA

    Background/Purpose: Systemic lupus erythematosus (SLE) pregnancy is associated with a heightened risk of adverse pregnancy outcomes, including preeclampsia. Distinguishing preeclampsia from lupus nephritis (LN) presents…
  • Abstract Number: 0478 • ACR Convergence 2024

    Skin Sodium in Patients with Rheumatoid Arthritis: Association with Blood Pressure and Disease Activity

    Carolina Ramirez, Annette Oeser, Rachelle Crescenzi, C. Michael Stein and Michelle Ormseth, Vanderbilt University Medical Center, Nashville, TN

    Background/Purpose: Sodium is stored in tissues such as the skin where it may contribute to development and progression of autoimmune diseases and hypertension through activation…
  • Abstract Number: 2501 • ACR Convergence 2024

    Long-term Remission off Therapy (LTROT) Is Possible in Non-infectious Aortitis with DMARDs with Low Risk of Secondary Adrenal Insufficiency

    Rohit Vijjhalwar1, Vithushanan Ketheeswaranathan2, Aman More2, Rajinder Andev3 and Shirish Dubey4, 1University of Oxford, Staines, United Kingdom, 2Medical Sciences Division, University of Oxford, Oxford, United Kingdom, 3Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom, 4Oxford University Hospitals NHS FT, Oxford, United Kingdom

    Background/Purpose: Non-infectious Aortitis is a rare form of large vessel vasculitis which has a high risk of complications1. There is limited data on the management…
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